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Tianbo Li

Affiliations: 
Yale University School of Medicine, New Haven, CT 
Area:
ion channels
Google:
"Tianbo Li"
Mean distance: 106866
 
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Li T, Yang Y, Canessa CM. (2014) A method for activation of endogenous acid-sensing ion channel 1a (ASIC1a) in the nervous system with high spatial and temporal precision. The Journal of Biological Chemistry. 289: 15441-8
Li T, Yang Y, Canessa CM. (2012) Impact of recovery from desensitization on acid-sensing ion channel-1a (ASIC1a) current and response to high frequency stimulation. The Journal of Biological Chemistry. 287: 40680-9
Li T, Yang Y, Canessa CM. (2011) Outlines of the pore in open and closed conformations describe the gating mechanism of ASIC1. Nature Communications. 2: 399
Li T, Yang Y, Canessa CM. (2011) Asp433 in the closing gate of ASIC1 determines stability of the open state without changing properties of the selectivity filter or Ca2+ block. The Journal of General Physiology. 137: 289-97
Li T, Yang Y, Canessa C. (2011) D433 Does Not Determine Ion Selectivity in ASIC1 Biophysical Journal. 100: 25a
Li T, Yang Y, Canessa CM. (2010) Asn415 in the beta11-beta12 linker decreases proton-dependent desensitization of ASIC1. The Journal of Biological Chemistry. 285: 31285-91
Li T, Yang Y, Canessa CM. (2010) Leu85 in the beta1-beta2 linker of ASIC1 slows activation and decreases the apparent proton affinity by stabilizing a closed conformation. The Journal of Biological Chemistry. 285: 22706-12
Li T, Yang Y, Canessa CM. (2010) Two residues in the extracellular domain convert a nonfunctional ASIC1 into a proton-activated channel. American Journal of Physiology. Cell Physiology. 299: C66-73
Li T, Canessa CM. (2010) The β1-β2 Linker in the Extracellular Domain of ASIC1 Determines Desensitization of ASIC1 Biophysical Journal. 98: 702a
Li T, Yang Y, Canessa CM. (2009) Interaction of the aromatics Tyr-72/Trp-288 in the interface of the extracellular and transmembrane domains is essential for proton gating of acid-sensing ion channels. The Journal of Biological Chemistry. 284: 4689-94
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