Donard S. Dwyer

Affiliations: 
Louisiana State University Health Sciences Center - Shreveport 
Area:
Pharmacology, Neuroscience Biology
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"Donard Dwyer"
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Publications

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Kasap M, Dwyer DS. (2020) Clozapine, nimodipine and endosulfan differentially suppress behavioral defects caused by gain-of-function mutations in a two-pore domain K channel (UNC-58). Neuroscience Research
Kasap M, Aamodt EJ, Sagrera CE, et al. (2019) Novel pharmacological modulation of dystonic phenotypes caused by a gain-of-function mutation in the Na+ leak-current channel. Behavioural Pharmacology
Tian X, Richard A, El-Saadi MW, et al. (2019) Dosage sensitivity intolerance of VIPR2 microduplication is disease causative to manifest schizophrenia-like phenotypes in a novel BAC transgenic mouse model. Molecular Psychiatry
Dwyer DS, Aamodt E, Cohen B, et al. (2014) Drug elucidation: invertebrate genetics sheds new light on the molecular targets of CNS drugs. Frontiers in Pharmacology. 5: 177
Dwyer DS, Aamodt EJ. (2013) Insulin/IGF-1 signaling, including class II/III PI3Ks, β-arrestin and SGK-1, is required in C. elegans to maintain pharyngeal muscle performance during starvation. Plos One. 8: e63851
Weeks KR, Dwyer DS, Aamodt EJ. (2011) Clozapine and lithium require Caenorhabditis elegans β-arrestin and serum- and glucocorticoid-inducible kinase to affect Daf-16 (FOXO) localization. Journal of Neuroscience Research. 89: 1658-65
Weeks KR, Dwyer DS, Aamodt EJ. (2010) Antipsychotic drugs activate the C. elegans akt pathway via the DAF-2 insulin/IGF-1 receptor. Acs Chemical Neuroscience. 1: 463-73
Williams B, Dwyer DS. (2009) Structure-based discovery of low molecular weight compounds that stimulate neurite outgrowth and substitute for nerve growth factor. Journal of Neurochemistry. 110: 1876-84
Donohoe DR, Jarvis RA, Weeks K, et al. (2009) Behavioral adaptation in C. elegans produced by antipsychotic drugs requires serotonin and is associated with calcium signaling and calcineurin inhibition. Neuroscience Research. 64: 280-9
Dwyer DS, Weeks K, Aamodt EJ. (2008) Drug discovery based on genetic and metabolic findings in schizophrenia. Expert Review of Clinical Pharmacology. 1: 773-89
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