Robert Tamayev, Ph.D.

Affiliations: 
2013 Yeshiva University, New York, NY, United States 
Area:
Philosophy of Science
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Luciano D'Adamio grad student 2013 Yeshiva University
 (A novel mouse model of dementia implicates beta-secretase, Thr668 of APP, and Tau in the pathogenesis of Alzheimer's Disease.)
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Publications

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Lombino F, Biundo F, Tamayev R, et al. (2013) An intracellular threonine of amyloid-β precursor protein mediates synaptic plasticity deficits and memory loss. Plos One. 8: e57120
Tamayev R, Akpan N, Arancio O, et al. (2012) Caspase-9 mediates synaptic plasticity and memory deficits of Danish dementia knock-in mice: caspase-9 inhibition provides therapeutic protection. Molecular Neurodegeneration. 7: 60
Matrone C, Luvisetto S, La Rosa LR, et al. (2012) Tyr682 in the Aβ-precursor protein intracellular domain regulates synaptic connectivity, cholinergic function, and cognitive performance. Aging Cell. 11: 1084-93
Tamayev R, D'Adamio L. (2012) Inhibition of γ-secretase worsens memory deficits in a genetically congruous mouse model of Danish dementia. Molecular Neurodegeneration. 7: 19
Tamayev R, D'Adamio L. (2012) Memory deficits of British dementia knock-in mice are prevented by Aβ-precursor protein haploinsufficiency. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5481-5
Tamayev R, Matsuda S, Arancio O, et al. (2012) β- but not γ-secretase proteolysis of APP causes synaptic and memory deficits in a mouse model of dementia. Embo Molecular Medicine. 4: 171-9
Tamayev R, Matsuda S, D’Adamio L. (2012) β - but not γ-secretase proteolysis of APP causes synaptic and memory deficits in a mouse model of dementia Molecular Neurodegeneration. 7: 1-2
Matsuda S, Tamayev R, D'Adamio L. (2011) Increased AβPP processing in familial Danish dementia patients. Journal of Alzheimer's Disease : Jad. 27: 385-91
Tamayev R, Matsuda S, Giliberto L, et al. (2011) APP heterozygosity averts memory deficit in knockin mice expressing the Danish dementia BRI2 mutant. The Embo Journal. 30: 2501-9
Barbagallo AP, Weldon R, Tamayev R, et al. (2010) Tyr(682) in the intracellular domain of APP regulates amyloidogenic APP processing in vivo. Plos One. 5: e15503
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