Laura L. Dugan

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 
Area:
Biochemistry, Neuroscience Biology
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"Laura Dugan"
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Publications

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Ruden JB, Quick KL, Gonzales ER, et al. (2019) Reduction of Leukocyte Microvascular Adherence and Preservation of Blood-Brain Barrier Function by Superoxide-Lowering Therapies in a Piglet Model of Neonatal Asphyxia. Frontiers in Neurology. 10: 447
Hardt JI, Perlmutter JS, Smith CJ, et al. (2018) Pharmacokinetics and Toxicology of the Neuroprotective e,e,e-Methanofullerene(60)-63-tris Malonic Acid [C] in Mice and Primates. European Journal of Drug Metabolism and Pharmacokinetics
Dugan LL, Tian L, Quick KL, et al. (2014) Carboxyfullerene neuroprotection postinjury in Parkinsonian nonhuman primates. Annals of Neurology. 76: 393-402
Chu W, Chepetan A, Zhou D, et al. (2014) Development of a PET radiotracer for non-invasive imaging of the reactive oxygen species, superoxide, in vivo. Organic & Biomolecular Chemistry. 12: 4421-31
Dugan LL, You YH, Ali SS, et al. (2013) AMPK dysregulation promotes diabetes-related reduction of superoxide and mitochondrial function. The Journal of Clinical Investigation. 123: 4888-99
Canzoniero LM, Granzotto A, Turetsky DM, et al. (2013) nNOS(+) striatal neurons, a subpopulation spared in Huntington's Disease, possess functional NMDA receptors but fail to generate mitochondrial ROS in response to an excitotoxic challenge. Frontiers in Physiology. 4: 112
Ali SS, Hsiao M, Zhao HW, et al. (2012) Hypoxia-adaptation involves mitochondrial metabolic depression and decreased ROS leakage. Plos One. 7: e36801
Pamenter ME, Ali SS, Tang Q, et al. (2012) An in vitro ischemic penumbral mimic perfusate increases NADPH oxidase-mediated superoxide production in cultured hippocampal neurons. Brain Research. 1452: 165-72
Hall DJ, Han SH, Chepetan A, et al. (2012) Dynamic optical imaging of metabolic and NADPH oxidase-derived superoxide in live mouse brain using fluorescence lifetime unmixing. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 23-32
Ali SS, Young JW, Wallace CK, et al. (2011) Initial evidence linking synaptic superoxide production with poor short-term memory in aged mice. Brain Research. 1368: 65-70
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