Adam L. Orr, Ph.D.
Affiliations: | 2008 | Emory University, Atlanta, GA |
Area:
Neuroscience BiologyGoogle:
"Adam Orr"Mean distance: 19430.2
Parents
Sign in to add mentor| Xiao-Jiang Li | grad student | 2008 | Emory | |
| (Pathogenic mechanisms of Huntington's disease: Soluble mutant huntingtin impairs mitochondrial transport directly.) | ||||
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Publications
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| Orr AL, Kim C, Jimenez-Morales D, et al. (2019) Neuronal Apolipoprotein E4 Expression Results in Proteome-Wide Alterations and Compromises Bioenergetic Capacity by Disrupting Mitochondrial Function. Journal of Alzheimer's Disease : Jad |
| Wong HS, Monternier PA, Orr AL, et al. (2018) Plate-Based Measurement of Superoxide and Hydrogen Peroxide Production by Isolated Mitochondria. Methods in Molecular Biology (Clifton, N.J.). 1782: 287-299 |
| Pathak D, Berthet A, Bendor JT, et al. (2017) Loss of α-Synuclein Does Not Affect Mitochondrial Bioenergetics in Rodent Neurons. Eneuro. 4 |
| Brand MD, Goncalves RL, Orr AL, et al. (2016) Suppressors of Superoxide-H2O2 Production at Site IQ of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury. Cell Metabolism |
| Orr AL, Vargas L, Turk CN, et al. (2015) Suppressors of superoxide production from mitochondrial complex III. Nature Chemical Biology. 11: 834-6 |
| Orr AL, Ashok D, Sarantos MR, et al. (2014) Novel inhibitors of mitochondrial sn-glycerol 3-phosphate dehydrogenase. Plos One. 9: e89938 |
| Brand MD, Quinlan CL, Goncalves RL, et al. (2014) Characterization and suppression of mitochondrial production of superoxide and hydrogen peroxide under near-physiological conditions Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1837: e57 |
| Orr AL, Ashok D, Sarantos MR, et al. (2013) Inhibitors of ROS production by the ubiquinone-binding site of mitochondrial complex I identified by chemical screening. Free Radical Biology & Medicine. 65: 1047-59 |
| Brand MD, Orr AL, Perevoshchikova IV, et al. (2013) The role of mitochondrial function and cellular bioenergetics in ageing and disease. The British Journal of Dermatology. 169: 1-8 |
| Orr AL, Quinlan CL, Perevoshchikova IV, et al. (2012) A refined analysis of superoxide production by mitochondrial sn-glycerol 3-phosphate dehydrogenase. The Journal of Biological Chemistry. 287: 42921-35 |