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Jing Fan, Ph.D

Affiliations: 
Psychiatry University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
NMDA receptors, Huntington's disease, excitotoxicity, cell death/survival signaling
Google:
"Jing Fan"
Bio:

I received my B.S. in 2003, at Peking University, School of Life Sciences. Then I had one year training in Lab of Molecular Virology, Inst. of Microbiology, Chinese Academy of Sciences, as a research assistant. I did my Ph.D in Dr. Lynn Raymond's lab at UBC (Neurosceince program), Canada, and graduated in 2011.

Mean distance: 15.72 (cluster 11)
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Lynn Raymond grad student 2004-2012 UBC

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Publications

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Gladding CM, Fan J, Zhang LY, et al. (2014) Alterations in STriatal-Enriched protein tyrosine Phosphatase expression, activation, and downstream signaling in early and late stages of the YAC128 Huntington's disease mouse model. Journal of Neurochemistry. 130: 145-59
Park KH, Lu G, Fan J, et al. (2012) Decreasing Levels of the cdk5 Activators, p25 and p35, Reduces Excitotoxicity in Striatal Neurons. Journal of Huntington's Disease. 1
Milnerwood AJ, Kaufman AM, Sepers MD, et al. (2012) Mitigation of augmented extrasynaptic NMDAR signaling and apoptosis in cortico-striatal co-cultures from Huntington's disease mice. Neurobiology of Disease. 48: 40-51
Fan J, Gladding CM, Wang L, et al. (2012) P38 MAPK is involved in enhanced NMDA receptor-dependent excitotoxicity in YAC transgenic mouse model of Huntington disease. Neurobiology of Disease. 45: 999-1009
Fan J, Vasuta OC, Zhang LY, et al. (2010) N-methyl-D-aspartate receptor subunit- and neuronal-type dependence of excitotoxic signaling through post-synaptic density 95. Journal of Neurochemistry. 115: 1045-56
McConoughey SJ, Basso M, Niatsetskaya ZV, et al. (2010) Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease. Embo Molecular Medicine. 2: 349-70
Fan J, Cowan CM, Zhang LY, et al. (2009) Interaction of postsynaptic density protein-95 with NMDA receptors influences excitotoxicity in the yeast artificial chromosome mouse model of Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 10928-38
Cowan CM, Fan MM, Fan J, et al. (2008) Polyglutamine-modulated striatal calpain activity in YAC transgenic huntington disease mouse model: impact on NMDA receptor function and toxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12725-35
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