Wayne Bowen, Ph.D.

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Liu CZ, Mottinelli M, Nicholson HE, et al. (2021) Identification and characterization of MAM03055A: a novel bivalent sigma-2 receptor/TMEM97 ligand with cytotoxic activity. European Journal of Pharmacology. 174263
Nicholson HE, Alsharif WF, Comeau AB, et al. (2018) Divergent Cytotoxic and Metabolically Stimulative Functions of Sigma-2 Receptors: Structure-activity Relationships of 6-acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79) Derivatives. The Journal of Pharmacology and Experimental Therapeutics
Maeda DY, Williams W, Kim WE, et al. (2002) N-arylalkylpiperidines as high-affinity sigma-1 and sigma-2 receptor ligands: phenylpropylamines as potential leads for selective sigma-2 agents. Bioorganic & Medicinal Chemistry Letters. 12: 497-500
Maeda DY, Williams W, Bowen WD, et al. (2000) A sigma-1 receptor selective analogue of BD1008. A potential substitute for (+)-opioids in sigma receptor binding assays. Bioorganic & Medicinal Chemistry Letters. 10: 17-8
Kedjouar B, Daunes S, Vilner BJ, et al. (1999) Structural similitudes between cytotoxic antiestrogen-binding site (AEBS) ligands and cytotoxic sigma receptor ligands. Evidence for a relationship between cytotoxicity and affinity for AEBS or sigma-2 receptor but not for sigma-1 receptor. Biochemical Pharmacology. 58: 1927-39
Helsley S, Filipink RA, Bowen WD, et al. (1998) The effects of sigma, PCP, and opiate receptor ligands in rats trained with ibogaine as a discriminative stimulus. Pharmacology, Biochemistry, and Behavior. 59: 495-503
John CS, Lim BB, Geyer BC, et al. (1997) 99mTc-labeled sigma-receptor-binding complex: synthesis, characterization, and specific binding to human ductal breast carcinoma (T47D) cells. Bioconjugate Chemistry. 8: 304-9
Chien CC, Carroll FI, Brown GP, et al. (1997) Synthesis and characterization of [125I]3'-(-)-iodopentazocine, a selective sigma 1 receptor ligand. European Journal of Pharmacology. 321: 361-8
Matsumoto RR, Bowen WD, Walker JM, et al. (1996) Dissociation of the motor effects of (+)-pentazocine from binding to sigma 1 sites. European Journal of Pharmacology. 301: 31-40
Matsumoto RR, Bowen WD, Tom MA, et al. (1995) Characterization of two novel σ receptor ligands: antidystonic effects in rats suggest σ receptor antagonism European Journal of Pharmacology. 280: 301-310