Jason D. Tucker, Ph.D.

Affiliations: 
2014 Biology University of North Carolina, Charlotte, Charlotte, NC, United States 
Area:
Genetics, Neuroscience Biology, Molecular Biology
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"Jason Tucker"
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Qi-Long Lu grad student 2014 UNC Charlotte
 (Polymer mediated delivery of oligonucleotide and trans genes toward more efficient and specific therapies for dystrophinopathies and dystroglycanopathies.)
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Publications

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Cataldi MP, Vannoy CH, Blaeser A, et al. (2023) Improved efficacy of FKRP AAV gene therapy by combination with ribitol treatment for LGMD2I. Molecular Therapy : the Journal of the American Society of Gene Therapy
Tucker JD, Doddapaneni R, Lu PJ, et al. (2022) Ribitol alters multiple metabolic pathways of central carbon metabolism with enhanced glycolysis: A metabolomics and transcriptomics profiling of breast cancer. Plos One. 17: e0278711
Wu B, Drains M, Shah SN, et al. (2022) Ribitol dose-dependently enhances matriglycan expression and improves muscle function with prolonged life span in limb girdle muscular dystrophy 2I mouse model. Plos One. 17: e0278482
Lu PJ, Tucker JD, Branch EK, et al. (2020) Ribitol enhances matriglycan of α-dystroglycan in breast cancer cells without affecting cell growth. Scientific Reports. 10: 4935
Wang M, Wu B, Tucker JD, et al. (2020) Triazine-cored polymeric vectors for antisense oligonucleotide delivery in vitro and in vivo. Journal of Nanobiotechnology. 18: 34
Tucker JD, Lu PJ, Xiao X, et al. (2018) Overexpression of Mutant FKRP Restores Functional Glycosylation and Improves Dystrophic Phenotype in FKRP Mutant Mice. Molecular Therapy. Nucleic Acids. 11: 216-227
Wang M, Wu B, Tucker JD, et al. (2017) A combinatorial library of triazine-cored polymeric vectors for pDNA delivery in vitro and in vivo. Journal of Materials Chemistry. B. 5: 3907-3918
Wang M, Wu B, Lu P, et al. (2017) Evaluation of Amphiphilic Peptide Modified Antisense Morpholino Oligonucleotides In Vitro and in Dystrophic mdx Mice. Polymers. 9
Wang M, Wu B, Tucker JD, et al. (2017) Tween 85-Modified Low Molecular Weight PEI Enhances Exon-Skipping of Antisense Morpholino Oligomer In Vitro and in mdx Mice. Molecular Therapy. Nucleic Acids. 9: 120-131
Wang M, Wu B, Tucker JD, et al. (2016) Poly(ester amine) Composed of Polyethylenimine and Pluronic Enhance Delivery of Antisense Oligonucleotides In Vitro and in Dystrophic mdx Mice. Molecular Therapy. Nucleic Acids. 5: e341
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