Junying Yuan, Ph.D
Affiliations: | Harvard Medical School, Boston, MA, United States |
Area:
Mechanisms of Programmed Cell DeathWebsite:
http://cellbio.med.harvard.edu/people/faculty/yuanGoogle:
"Junying Yuan"Bio:
Mean distance: 15.32 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentor| H. Robert Horvitz | grad student | 1983-1991 | Harvard & MIT | |
| (Genetic and molecular studies of ced-3 and ced-4 : two genes that control programmed cell death in the nematode C. elegans.) | ||||
Children
Sign in to add trainee| Lauren Mifflin | grad student | 2016- | Harvard Medical School |
| Dimitry Ofengeim | post-doc | Harvard Medical School |
BETA: Related publications
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Publications
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| Guo R, Liu J, Min X, et al. (2024) Reduction of DHHC5-mediated beclin 1 S-palmitoylation underlies autophagy decline in aging. Nature Structural & Molecular Biology |
| Yuan J, Ofengeim D. (2023) A guide to cell death pathways. Nature Reviews. Molecular Cell Biology |
| Zhang T, Xu D, Liu J, et al. (2023) Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation. Nature Cell Biology |
| Zhang T, Xu D, Trefts E, et al. (2023) Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1. Science (New York, N.Y.). 380: 1372-1380 |
| Li W, Yuan J. (2023) Targeting RIPK1 kinase for modulating inflammation in human diseases. Frontiers in Immunology. 14: 1159743 |
| Li Y, Zou C, Chen C, et al. (2023) Myeloid-derived MIF drives RIPK1-mediated cerebromicrovascular endothelial cell death to exacerbate ischemic brain injury. Proceedings of the National Academy of Sciences of the United States of America. 120: e2219091120 |
| Dong K, Wei R, Jin T, et al. (2022) HOIP modulates the stability of GPx4 by linear ubiquitination. Proceedings of the National Academy of Sciences of the United States of America. 119: e2214227119 |
| Wu G, Li D, Liang W, et al. (2022) PP6 negatively modulates LUBAC-mediated M1-ubiquitination of RIPK1 and c-FLIP to promote TNFα-mediated cell death. Cell Death & Disease. 13: 773 |
| Li W, Shan B, Zou C, et al. (2022) Nuclear RIPK1 promotes chromatin remodeling to mediate inflammatory response. Cell Research |
| Xu D, Zou C, Yuan J. (2021) Genetic Regulation of RIPK1 and Necroptosis. Annual Review of Genetics. 55: 235-263 |