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Lionel Muller Igaz

Affiliations: 
School of Medicine, University of Buenos Aires, Argentina, Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina 
Area:
memory, neurodegeneration, TDP-43 pathophysiology
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"Lionel Muller Igaz"
Mean distance: 15.89 (cluster 24)
 		SNBCP
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Parents

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Jorge Horacio Medina grad student 2001-2006 School of Medicine, University of Buenos Aires, Argentina
Virginia Man-Yee Lee post-doc 2006-2010 Penn
John Q. Trojanowski post-doc 2006-2010 Penn

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Publications

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Gonzalez MC, Villar ME, Igaz LM, et al. (2015) Dorsal medial prefrontal cortex contributes to conditioned taste aversion memory consolidation and retrieval. Neurobiology of Learning and Memory
Igaz LM, Kwong LK, Lee EB, et al. (2011) Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice. The Journal of Clinical Investigation. 121: 726-38
Igaz LM, Kwong LK, Chen-Plotkin A, et al. (2009) Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies. The Journal of Biological Chemistry. 284: 8516-24
Igaz LM, Kwong LK, Xu Y, et al. (2008) Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis. The American Journal of Pathology. 173: 182-94
Winton MJ, Igaz LM, Wong MM, et al. (2008) Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation. The Journal of Biological Chemistry. 283: 13302-9
Geser F, Winton MJ, Kwong LK, et al. (2008) Pathological TDP-43 in parkinsonism-dementia complex and amyotrophic lateral sclerosis of Guam. Acta Neuropathologica. 115: 133-45
Neumann M, Igaz LM, Kwong LK, et al. (2007) Absence of heterogeneous nuclear ribonucleoproteins and survival motor neuron protein in TDP-43 positive inclusions in frontotemporal lobar degeneration. Acta Neuropathologica. 113: 543-8
Bekinschtein P, Cammarota M, Igaz LM, et al. (2007) Persistence of long-term memory storage requires a late protein synthesis- and BDNF- dependent phase in the hippocampus. Neuron. 53: 261-77
Bekinschtein P, Katche C, Slipczuk LN, et al. (2007) mTOR signaling in the hippocampus is necessary for memory formation. Neurobiology of Learning and Memory. 87: 303-7
Igaz LM, Winograd M, Cammarota M, et al. (2006) Early activation of extracellular signal-regulated kinase signaling pathway in the hippocampus is required for short-term memory formation of a fear-motivated learning. Cellular and Molecular Neurobiology. 26: 989-1002
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