Sascha R.A. Alles, Ph.D.
Affiliations: | 2019- | Department of Anesthesiology and Critical Care Medicine | University of New Mexico School of Medicine |
Area:
Chronic pain, nociception, ion channelsWebsite:
www.alleslab.comGoogle:
"Sascha Alles"Bio:
Dr. Alles completed his undergraduate degree in Biochemistry at Imperial College London (2010) and his PhD in Neuroscience at the University of Alberta (2016). His PhD with Professor Peter Smith focused on the spinal electrophysiological mechanisms of the gabapentinoid drugs for neuropathic pain. He then went on to complete Postdoctoral Fellowships at the University of British Columbia with Professor Terry Snutch (2017) and at University College London with Professor John Wood (2019). His work focused on understanding chronic pain mechanisms and ion channel biology, which facilitated unique insights into novel therapeutics for treating pain, such as those impacting the ion channel Nav1.7. Dr. Alles joined the faculty at the Department of Anesthesiology & Critical Care Medicine at the University of New Mexico Health Sciences Center in 2019.
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Parents
Sign in to add mentor| Peter A. Smith | grad student | 2011-2016 | University of Alberta |
| Terry P. Snutch | post-doc | 2016-2017 | UBC |
| John N. Wood | post-doc | 2017-2019 | University College London |
Children
Sign in to add trainee| Aleyah Goins | research assistant | 2019-2021 | University of New Mexico School of Medicine |
Collaborators
Sign in to add collaborator| Karin Westlund High | collaborator | 2019- | University of New Mexico School of Medicine |
| Michael Blake Hoppa | collaborator | 2020- | Dartmouth |
| Rajesh Khanna | collaborator | 2020- | University of Arizona |
| Aubin Moutal | collaborator | 2020- | University of Arizona |
| Ian Winship | collaborator | 2014-2016 | University of Alberta |
| Glen Baker | collaborator | 2015-2017 | University of Alberta |
| Brian A. Macvicar | collaborator | 2016-2017 | UBC |
| Marco Beato | collaborator | 2018-2019 | UCL |
Publications
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| Ehsanian R, Koshkin E, Goins AE, et al. (2021) Pre- and Post-Interventional Changes in Physiological Profiles in a Patient Presenting With Opioid Withdrawal After Intrathecal Drug Delivery System Failure Related to Assumed Catheter Microfracture Cureus. 13: e14835 |
| Garcia-Caballero A, Zhang FX, Hodgkinson V, et al. (2018) T-type calcium channels functionally interact with spectrin (α/β) and ankyrin B. Molecular Brain. 11: 24 |
| Cain SM, Bohnet B, LeDue J, et al. (2017) In vivo imaging reveals that pregabalin inhibits cortical spreading depression and propagation to subcortical brain structures. Proceedings of the National Academy of Sciences of the United States of America |
| Alles SR, Bandet MV, Eppler K, et al. (2016) Acute anti-allodynic action of gabapentin in dorsal horn and primary somatosensory cortex: Correlation of behavioural and physiological data. Neuropharmacology |
| Alles SR, Smith PA. (2016) The Anti-Allodynic Gabapentinoids: Myths, Paradoxes, and Acute Effects. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry |