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Ludovic Renault

Affiliations: 
2016- NeCEN Leiden University, Leiden, Netherlands 
Website:
http://necen.nl
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Parents

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Pascale Marchot grad student 2002-2005 Aix Marseille 2
 (Approche structurale de l'inhibition de l'acétylcholinestérase par des anticorps monoclonaux)
Henning Stahlberg post-doc 2006-2009 UC Davis (Physics Tree)
Howard S. Young research scientist 2009-2012 University of Alberta (Chemistry Tree)

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Publications

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Frigola J, He J, Kinkelin K, et al. (2017) Cdt1 stabilizes an open MCM ring for helicase loading. Nature Communications. 8: 15720
Zhou JC, Janska A, Goswami P, et al. (2017) CMG-Pol epsilon dynamics suggests a mechanism for the establishment of leading-strand synthesis in the eukaryotic replisome. Proceedings of the National Academy of Sciences of the United States of America
Swuec P, Renault L, Borg A, et al. (2016) The FA Core Complex Contains a Homo-dimeric Catalytic Module for the Symmetric Mono-ubiquitination of FANCI-FANCD2. Cell Reports
Vázquez-Fernández E, Vos MR, Afanasyev P, et al. (2016) The Structural Architecture of an Infectious Mammalian Prion Using Electron Cryomicroscopy. Plos Pathogens. 12: e1005835
Abid Ali F, Renault L, Gannon J, et al. (2016) Cryo-EM structures of the eukaryotic replicative helicase bound to a translocation substrate. Nature Communications. 7: 10708
Maskell DP, Renault L, Serrao E, et al. (2015) Structural basis for retroviral integration into nucleosomes. Nature. 523: 366-9
Pike AC, Gomathinayagam S, Swuec P, et al. (2015) Human RECQ1 helicase-driven DNA unwinding, annealing, and branch migration: insights from DNA complex structures. Proceedings of the National Academy of Sciences of the United States of America. 112: 4286-91
Bourne Y, Renault L, Marchot P. (2015) Crystal structure of snake venom acetylcholinesterase in complex with inhibitory antibody fragment Fab410 bound at the peripheral site: evidence for open and closed states of a back door channel. The Journal of Biological Chemistry. 290: 1522-35
Costa A, Renault L, Swuec P, et al. (2014) DNA binding polarity, dimerization, and ATPase ring remodeling in the CMG helicase of the eukaryotic replisome. Elife. 3: e03273
Simon AC, Zhou JC, Perera RL, et al. (2014) A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome. Nature. 510: 293-7
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