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Leslie Hough

Affiliations: 
Chemistry King's College London, London, UK 
Area:
carbohydrate chemistry
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"Leslie Hough"
Bio:

Leslie Hough was born in 1925 in Lancashire. He graduated in 1946 from the University of Manchester with an Honors degree in Chemistry. He commenced research on carbohydrates with Professor (later Sir Edmund) E. L. Hirst and Dr. (later Professor) J.K.N. Jones, took the M.Sc. in 1947 and completed his Ph.D. in 1949. Collaboration with Jones continued when Dr. Hough joined the academic staff at the University of Bristol in 1950. As a Fulbright Scholar he took sabbatical leave in 1952 to study at Purdue University with Professor Roy L. Whistler. When J.K.N. Jones became the Chown Research Professor at Queens University, Ontario, in 1954, Dr. Hough directed the carbohydrate research at Bristol on glycoproteins, carbon-14 tracer studies and the interplay between conformation and reactivity. Research on sucrose commenced in 1956 with the support of the International Sugar Research Foundation (now W.R.S.O.) and continued with Tate and Lyle.
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Parents

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Edmund Langley Hirst grad student 1949 University of Manchester
J. Ken N. (John Kenyon Netherton) Jones grad student 1949 University of Manchester
Roy L. Whistler research scientist 1952 Purdue

Children

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Jack B Pridham grad student 1956 University of Bristol
Philip D. Bragg grad student 1958 University of Bristol
Anthony C. Richardson grad student 1956-1959 University of Bristol
Bruce Coxon grad student 1960 University of Bristol
Laurance David Hall grad student 1963 University of Bristol

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Publications

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Hough L, McCarthy KC, Richardson AC. (2010) The preparation and reactions of 2‐halogenoethyl β‐L‐arabinopyranosides Recueil Des Travaux Chimiques Des Pays-Bas. 110: 450-458
Hough L, Richardson AC. (2008) The Monosaccharides: Pentoses, Hexoses, Heptoses and Higher Sugars Rodd's Chemistry of Carbon Compounds: a Modern Comprehensive Treatise: Second Edition. 1: 67-595
Hough L, Richardson AC. (2008) Penta-, Hexa- and Higher Polyhydric Alcohols Rodd's Chemistry of Carbon Compounds: a Modern Comprehensive Treatise: Second Edition. 1: 1-66
Machinami T, Fujimoto T, Takatsuka A, et al. (2002) Design and synthesis of new sweeteners Pure and Applied Chemistry. 74: 1219-1225
Machinami T, Iibuchi N, Nomura T, et al. (2002) Synthesis of aminoacyl sugar derivatives and their taste characteristics. I. 2,3-Di-O-aminoacyl derivatives of alkyl D-glucopyranosides Journal of Carbohydrate Chemistry. 21: 131-142
Ali MA, Hough L, Richardson AC. (1992) Thio and epidithio derivatives of methyl β-lactoside Carbohydrate Research. 216: 271-287
Aamlid KH, Hough L, Richardson AC. (1990) Synthesis of 1-deoxy-6-epicastanospermine and 1-deoxy-6,8a-diepicastanospermine Carbohydrate Research. 202: 117-129
Garcia RC, Hough L, Richardson AC. (1990) Syntheses of hepta-, hexa-, and penta-pivalates of trehalose by selective pivaloylation Carbohydrate Research. 200: 307-317
Bullock C, Hough L, Richardson AC. (1990) A novel route to 1,4-anhydro derivatives of β-d-galactopyranose Carbohydrate Research. 197: 131-138
Hendry D, Hough L, Richardson AC. (1988) Enantiospecific synthesis of polhydroxylated indolizidines related to castanospermine:1 (6R,7S,8aR)-6,7-dihydroxyindolizidine and (6R,7R,8S,8aR)-6,7,8-trihydroxyindolizidine Tetrahedron. 44: 6153-6168
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