David N Hauser

Affiliations: 
Sanford Burnham Prebys Medical Discovery Insitute 
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"David Hauser"
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Parents

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Teresa Hastings research assistant 2008
Mark R. Cookson grad student 2010-2015
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Publications

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Mazza MC, Beilina A, Roosen DA, et al. (2021) Generation of iPSC line from a Parkinson patient with PARK7 mutation and CRISPR-edited Gibco human episomal iPSC line to mimic PARK7 mutation. Stem Cell Research. 55: 102506
Klein MO, Battagello DS, Cardoso AR, et al. (2018) Dopamine: Functions, Signaling, and Association with Neurological Diseases. Cellular and Molecular Neurobiology
Langston RG, Rudenko IN, Kumaran R, et al. (2018) Differences in Stability, Activity and Mutation Effects Between Human and Mouse Leucine-Rich Repeat Kinase 2. Neurochemical Research
Pellegrini L, Hauser DN, Li Y, et al. (2018) Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice. Human Molecular Genetics
Hauser DN, Mamais A, Conti MM, et al. (2017) Hexokinases link DJ-1 to the PINK1/parkin pathway. Molecular Neurodegeneration. 12: 70
Hauser DN, Primiani CT, Cookson MR. (2016) The effects of variants in the PARK2 (parkin), PINK1, and PARK7 (DJ-1) genes along with evidence for their pathogenicity. Current Protein & Peptide Science
Hauser DN, Primiani CT, Langston RG, et al. (2015) The Polg Mutator Phenotype Does Not Cause Dopaminergic Neurodegeneration in DJ-1-Deficient Mice. Eneuro. 2
Mamais A, Chia R, Beilina A, et al. (2014) Arsenite stress down-regulates phosphorylation and 14-3-3 binding of leucine-rich repeat kinase 2 (LRRK2), promoting self-association and cellular redistribution. The Journal of Biological Chemistry. 289: 21386-400
Prahlad J, Hauser DN, Milkovic NM, et al. (2014) Use of cysteine-reactive cross-linkers to probe conformational flexibility of human DJ-1 demonstrates that Glu18 mutations are dimers. Journal of Neurochemistry. 130: 839-53
Hauser DN, Dillman AA, Ding J, et al. (2014) Post-translational decrease in respiratory chain proteins in the Polg mutator mouse brain. Plos One. 9: e94646
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