kun ping lu
Affiliations: | Medicine | Harvard Medical School, Boston, MA, United States |
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| Wang R, Lu KP, Zhou XZ. (2023) Function and regulation of cis P-tau in the pathogenesis and treatment of conventional and nonconventional tauopathies. Journal of Neurochemistry |
| Qiu C, Albayram O, Kondo A, et al. (2021) Cis P-tau underlies vascular contribution to cognitive impairment and dementia and can be effectively targeted by immunotherapy in mice. Science Translational Medicine. 13 |
| Pinch BJ, Doctor ZM, Nabet B, et al. (2020) Identification of a potent and selective covalent Pin1 inhibitor. Nature Chemical Biology |
| Chen D, Mei Y, Kim N, et al. (2020) Melatonin Directly Binds and Inhibits Death-Associated Protein Kinase 1 Function in Alzheimer's Disease. Journal of Pineal Research. e12665 |
| Luo ML, Zheng F, Chen W, et al. (2020) Inactivation of the prolyl isomerase Pin1 sensitizes BRCA1-proficient breast cancer to PARP inhibition. Cancer Research |
| Albayram O, MacIver B, Mathai J, et al. (2019) Traumatic Brain Injury-related voiding dysfunction in mice is caused by damage to rostral pathways, altering inputs to the reflex pathways. Scientific Reports. 9: 8646 |
| Chen L, Xu X, Wen X, et al. (2019) Targeting PIN1 exerts potent antitumor activity in pancreatic ductal carcinoma via inhibiting tumor metastasis. Cancer Science |
| Zhang Z, Yu W, Zheng M, et al. (2019) Pin1 inhibition potently suppresses gastric cancer growth and blocks PI3K/AKT and Wnt/β-catenin oncogenic pathways. Molecular Carcinogenesis |
| Pinch B, Doctor Z, Browne CM, et al. (2019) Abstract 2757: Discovery and characterization of covalent Pin1 inhibitors targeted to an active site cysteine Cancer Research. 79: 2757-2757 |
| Goldstein L, Minaeva O, Fisher AM, et al. (2019) P2-206: CONTRIBUTION OF FOCAL MICROVASCULAR DISRUPTION TO NEUROINFLAMMATION AND TAU PATHOLOGY IN A MOUSE MODEL OF IMPACT CONCUSSION AND CHRONIC TRAUMATIC ENCEPHALOPATHY Alzheimer's & Dementia. 15: P655-P656 |