Digvijay Singh

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
Biophysics, optics, single-molecule, fluorescence, Electron microscopy, Electron tomography, Molecular Biology, Biochemistry, CRISPR
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"Digvijay Singh"
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Parents

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Elizabeth Villa grad student 2018- UCSD (Chemistry Tree)
Taekjip Ha grad student 2012-2018 (Physics Tree)
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Publications

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Akey CW, Singh D, Ouch C, et al. (2021) Comprehensive structure and functional adaptations of the yeast nuclear pore complex. Cell
Dai L, Singh D, Lu S, et al. (2021) A viral genome packaging ring-ATPase is a flexibly coordinated pentamer. Nature Communications. 12: 6548
Poddar A, Azam MS, Kayikcioglu T, et al. (2021) Effects of individual base-pairs on in vivo target search and destruction kinetics of bacterial small RNA. Nature Communications. 12: 874
Lu S, Ye Q, Singh D, et al. (2021) The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein. Nature Communications. 12: 502
Wang Y, Mallon J, Wang H, et al. (2021) Real-time observation of Cas9 postcatalytic domain motions. Proceedings of the National Academy of Sciences of the United States of America. 118
Yu H, Lu S, Gasior K, et al. (2020) HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells. Science (New York, N.Y.)
Lu S, Ye Q, Singh D, et al. (2020) The SARS-CoV-2 Nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein. Biorxiv : the Preprint Server For Biology
Wagner FR, Watanabe R, Schampers R, et al. (2020) Preparing samples from whole cells using focused-ion-beam milling for cryo-electron tomography. Nature Protocols
Okafor IC, Singh D, Wang Y, et al. (2019) Single molecule analysis of effects of non-canonical guide RNAs and specificity-enhancing mutations on Cas9-induced DNA unwinding. Nucleic Acids Research
Singh D, Mallon J, Poddar A, et al. (2018) Real-time observation of DNA target interrogation and product release by the RNA-guided endonuclease CRISPR Cpf1 (Cas12a). Proceedings of the National Academy of Sciences of the United States of America
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