Robert Signer
Affiliations: | University of California, San Diego, La Jolla, CA | ||
| 2009-2015 | Children's Research Institute | University of Texas Southwestern Medical Center at Dallas, Dallas, TX, United States |
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Parents
Sign in to add mentor| Sean J. Morrison | post-doc | 2009-2015 | University of Texas Southwestern Medical Center at Dallas |
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Publications
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| Chua BA, Lennan CJ, Sunshine MJ, et al. (2023) Hematopoietic stem cells preferentially traffic misfolded proteins to aggresomes and depend on aggrephagy to maintain protein homeostasis. Cell Stem Cell |
| Kruta M, Sunshine MJ, Chua BA, et al. (2021) Hsf1 promotes hematopoietic stem cell fitness and proteostasis in response to ex vivo culture stress and aging. Cell Stem Cell |
| Magee JA, Signer RAJ. (2021) Developmental Stage-Specific Changes in Protein Synthesis Differentially Sensitize Hematopoietic Stem Cells and Erythroid Progenitors to Impaired Ribosome Biogenesis. Stem Cell Reports. 16: 20-28 |
| Lam K, Signer RAJ. (2020) ERADicating stem cells from their niche. Nature Cell Biology |
| Chua BA, Signer RAJ. (2020) Hematopoietic stem cell regulation by the proteostasis network. Current Opinion in Hematology |
| Chua BA, Van Der Werf I, Jamieson C, et al. (2020) Post-Transcriptional Regulation of Homeostatic, Stressed, and Malignant Stem Cells. Cell Stem Cell. 26: 138-159 |
| Hidalgo San Jose L, Sunshine MJ, Dillingham CH, et al. (2020) Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal. Cell Reports. 30: 69-80.e6 |
| Hidalgo San Jose L, Signer RAJ. (2019) Cell-type-specific quantification of protein synthesis in vivo. Nature Protocols |
| Signer R. (2019) Proteostasis and Myeloid Stem Cell Production Blood. 134 |
| Signer R, Kruta M, Sunshine MJ, et al. (2019) 2002 - Ex Vivo Activation Of Heat Shock Factor 1 (Hsf1) Promotes Sustained Hematopoietic Stem Cell Self-Renewal Experimental Hematology. 76 |