Ashley E. Frakes

Affiliations: 
Ohio State University, Columbus, Columbus, OH 
Area:
ALS, microglia
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"Ashley Frakes"
Mean distance: 22.43 (cluster 19)
 

Parents

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Brian K. Kaspar grad student Ohio State
Andrew Dillin post-doc UC Berkeley (Cell Biology Tree)
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Publications

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Metcalf MG, Monshietehadi S, Sahay A, et al. (2024) Cell non-autonomous control of autophagy and metabolism by glial cells. Iscience. 27: 109354
Gildea HK, Frankino PA, Tronnes SU, et al. (2022) Glia of coordinate a protective organismal heat shock response independent of the neuronal thermosensory circuit. Science Advances. 8: eabq3970
Ward CP, Peng L, Yuen S, et al. (2022) Aging alters the metabolic flux signature of the ER-unfolded protein response in vivo in mice. Aging Cell. e13558
Ward CP, Peng L, Yuen S, et al. (2022) ER Unfolded Protein Response in Liver In Vivo Is Characterized by Reduced, Not Increased, De Novo Lipogenesis and Cholesterol Synthesis Rates with Uptake of Fatty Acids from Adipose Tissue: Integrated Gene Expression, Translation Rates and Metabolic Fluxes. International Journal of Molecular Sciences. 23
Bar-Ziv R, Frakes AE, Higuchi-Sanabria R, et al. (2020) Measurements of Physiological Stress Responses in C. Elegans. Journal of Visualized Experiments : Jove
Frakes AE, Metcalf MG, Tronnes SU, et al. (2020) Four glial cells regulate ER stress resistance and longevity via neuropeptide signaling in . Science (New York, N.Y.). 367: 436-440
Frakes AE, Dillin A. (2017) The UPR(ER): Sensor and Coordinator of Organismal Homeostasis. Molecular Cell. 66: 761-771
Frakes AE, Braun L, Ferraiuolo L, et al. (2017) Additive amelioration of ALS by co-targeting independent pathogenic mechanisms. Annals of Clinical and Translational Neurology. 4: 76-86
Ferraiuolo L, Meyer K, Sherwood TW, et al. (2016) Oligodendrocytes contribute to motor neuron death in ALS via SOD1-dependent mechanism. Proceedings of the National Academy of Sciences of the United States of America
Ahmed SS, Schattgen SA, Frakes AE, et al. (2016) rAAV gene therapy in a Canavan's disease mouse model reveals immune impairments and an extended pathology beyond the central nervous system. Molecular Therapy : the Journal of the American Society of Gene Therapy
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