Jeffrey P MacKeigan
Affiliations: | Michigan State University, East Lansing, MI |
Area:
cancer biology, cancer genomics, target identification, rare diseaseWebsite:
mackeiganlab.orgGoogle:
"Jeffrey MacKeigan"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Jenny P-Y Ting | grad student | 1998-2002 | UNC School of Medicine |
| John Blenis | post-doc | 2003-2004 | Harvard Medical School |
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Publications
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| McPhail DK, Alzahrani MAM, Martin KR, et al. (2024) Loss of Tuberous Sclerosis Complex 2 confers inflammation via dysregulation of Nuclear factor kappa-light-chain-enhancer of activated B cells. Research Square |
| Vaughan RM, Dickson BM, Martin KR, et al. (2023) Molecular dynamics simulations provide insights into ULK-101 potency and selectivity toward autophagic kinases ULK1/2. Biorxiv : the Preprint Server For Biology |
| Martin KR, Celano SL, Sheldon RD, et al. (2023) Quantitative Analysis of Autophagy in Single Cells: Differential Response to Amino Acid and Glucose Starvation. Biorxiv : the Preprint Server For Biology |
| Chacon-Barahona JA, MacKeigan JP, Lanning NJ. (2023) Unique Metabolic Contexts Sensitize Cancer Cells and Discriminate between Glycolytic Tumor Types. Cancers. 15 |
| Giannikou K, Martin KR, Abdel-Azim AG, et al. (2023) Spectrum of germline and somatic mitochondrial DNA variants in Tuberous Sclerosis Complex. Frontiers in Genetics. 13: 917993 |
| Vaughan RM, Kordich JJ, Chan CY, et al. (2022) Chemical Biology Screening Identifies a Vulnerability to Checkpoint Kinase Inhibitors in TSC2-Deficient Renal Angiomyolipomas. Frontiers in Oncology. 12: 852859 |
| Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, et al. (2021) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382 |
| Celano SL, Yco LP, Kortus MG, et al. (2019) Identification of Kinases Responsible for p53-Dependent Autophagy. Iscience. 15: 109-118 |
| Guillaume JD, Celano SL, Martin KR, et al. (2019) Determining the Impact of Metabolic Nutrients on Autophagy. Methods in Molecular Biology (Clifton, N.J.). 1862: 151-162 |
| Martin KR, Celano SL, Solitro AR, et al. (2018) A Potent and Selective ULK1 Inhibitor Suppresses Autophagy and Sensitizes Cancer Cells to Nutrient Stress. Iscience. 8: 74-84 |