Katherine J. Wert, PhD

Affiliations: 
Whitehead Massachusetts Institute of Technology, Cambridge, MA, United States 
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"Katherine Wert"
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Stephen H. Tsang grad student 2013 Columbia
 (Gene Therapy Provides Long-term Visual Function in a Pre-clinical Model of Retinitis Pigmentosa.)
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Publications

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Yee T, Wert KJ. (2023) Human retina-in-a-dish: Unlocking the potential to study mechanisms of inherited retinal disease. Molecular Therapy. Methods & Clinical Development. 30: 573-575
Kong Y, Liu PK, Li Y, et al. (2023) HIF2α activation and mitochondrial deficit due to iron chelation cause retinal atrophy. Embo Molecular Medicine. e16525
Rowe AA, Chen X, Nettesheim ER, et al. (2022) Long-term progression of retinal degeneration in a preclinical model of CLN7 Batten disease as a baseline for testing clinical therapeutics. Ebiomedicine. 85: 104314
Yee T, Wert KJ. (2022) Base and Prime Editing in the Retina-From Preclinical Research toward Human Clinical Trials. International Journal of Molecular Sciences. 23
Rowe AA, Patel PD, Gordillo R, et al. (2021) Replenishment of TCA cycle intermediates provides photoreceptor resilience against neurodegeneration during progression of retinitis pigmentosa. Jci Insight
Tang PH, Chemudupati T, Wert KJ, et al. (2020) Phenotypic variance in Calpain-5 retinal degeneration. American Journal of Ophthalmology Case Reports. 18: 100627
Wert KJ, Velez G, Kanchustambham VL, et al. (2020) Metabolite therapy guided by liquid biopsy proteomics delays retinal neurodegeneration. Ebiomedicine. 52: 102636
Wert KJ, Koch SF, Velez G, et al. (2019) CAPN5 genetic inactivation phenotype supports therapeutic inhibition trials. Human Mutation
Wert KJ, Bakall B, Bassuk AG, et al. (2019) Insights into Retinal Development Using Live Imaging in Female Carriers of Choroideremia. Ophthalmic Surgery, Lasers & Imaging Retina. 50: e158-e162
Wert KJ, Mahajan VB. (2019) In Vivo Expression of Mutant Calpains in the Eye Using Lentivirus. Methods in Molecular Biology (Clifton, N.J.). 1915: 233-247
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