Mehdi Jorfi, Ph.D.
Affiliations: | Neurology | Harvard University, Cambridge, MA, United States |
Area:
Neurobiological Engineering, Alzheimer's diseaseWebsite:
https://www.jorfilab.com/Google:
"Mehdi Jorfi"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Christoph Weder | grad student | 2011-2014 | University of Fribourg (Chemistry Tree) |
| Paula T. Hammond | post-doc | (Chemistry Tree) | |
| Rudolph E. Tanzi | post-doc | ||
| Mehmet Toner | post-doc | (E-Tree) |
Collaborators
Sign in to add collaborator| Jeffrey R. Capadona | collaborator | (Chemistry Tree) | |
| Doo Yeon Kim | collaborator | Harvard Medical School - Massachusetts General Hospital |
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Publications
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| Ko EC, Spitz S, Pramotton FM, et al. (2023) Accelerating the in vitro emulation of Alzheimer's disease-associated phenotypes using a novel 3D blood-brain barrier neurosphere co-culture model. Frontiers in Bioengineering and Biotechnology. 11: 1251195 |
| Jorfi M, Park J, Hall CK, et al. (2023) Infiltrating CD8 T cells exacerbate Alzheimer's disease pathology in a 3D human neuroimmune axis model. Nature Neuroscience |
| Jorfi M, Maaser-Hecker A, Tanzi RE. (2023) The neuroimmune axis of Alzheimer's disease. Genome Medicine. 15: 6 |
| Ning S, Jorfi M, Patel SR, et al. (2022) Neurotechnological Approaches to the Diagnosis and Treatment of Alzheimer's Disease. Frontiers in Neuroscience. 16: 854992 |
| Lotlikar MS, Tarantino MB, Jorfi M, et al. (2022) Microfluidic separation of axonal and somal compartments of neural progenitor cells differentiated in a 3D matrix. Star Protocols. 3: 101028 |
| Kim JJ, Jorfi M, Tanzi RE, et al. (2021) Patterning of interconnected human brain spheroids. Lab On a Chip |
| McAlpine CS, Park J, Griciuc A, et al. (2021) Astrocytic interleukin-3 programs microglia and limits Alzheimer's disease. Nature |
| Bhattacharyya R, Black SE, Lotlikar MS, et al. (2021) Axonal generation of amyloid-β from palmitoylated APP in mitochondria-associated endoplasmic reticulum membranes. Cell Reports. 35: 109134 |
| von Maydell D, Jorfi M. (2021) A Synergistic Engineering Approach to Build Human Brain Spheroids. Methods in Molecular Biology (Clifton, N.J.). 2258: 151-169 |
| von Maydell D, Jorfi M. (2019) The interplay between microglial states and major risk factors in Alzheimer's disease through the eyes of single-cell RNA-sequencing: beyond black and white. Journal of Neurophysiology |