Ellen Welch

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"Ellen Welch"
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Luban J, Sattler R, Mühlberger E, et al. (2020) The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines. Virus Research. 198246
Luban J, Sattler R, Mühlberger E, et al. (2020) The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines. Biorxiv : the Preprint Server For Biology
Baiazitov RY, Friesen W, Johnson B, et al. (2020) Chemical modifications of G418 (geneticin): Synthesis of novel readthrough aminoglycosides results in an improved in vitro safety window but no improvements in vivo. Carbohydrate Research. 495: 108058
Kramerova I, Kumagai-Cresse C, Ermolova N, et al. (2019) Spp1 (osteopontin) promotes TGFβ processing in fibroblasts of dystrophin deficient muscles through matrix metalloproteinases. Human Molecular Genetics
Ng MY, Zhang H, Weil A, et al. (2018) New Assay Measuring Direct Interaction of Nonsense Suppressors with the Eukaryotic Protein Synthesis Machinery. Acs Medicinal Chemistry Letters. 9: 1285-1291
Friesen WJ, Johnson B, Sierra J, et al. (2018) The minor gentamicin complex component, X2, is a potent premature stop codon readthrough molecule with therapeutic potential. Plos One. 13: e0206158
Friesen WJ, Trotta CR, Tomizawa Y, et al. (2017) The nucleoside analog clitocine is a potent and efficacious readthrough agent. Rna (New York, N.Y.)
Roy B, Friesen WJ, Tomizawa Y, et al. (2016) Ataluren stimulates ribosomal selection of near-cognate tRNAs to promote nonsense suppression. Proceedings of the National Academy of Sciences of the United States of America
Moosajee M, Tracey-White D, Smart M, et al. (2016) Functional rescue of REP1 following treatment with PTC124 and novel derivative PTC-414 in human choroideremia fibroblasts and the nonsense-mediated zebrafish model. Human Molecular Genetics
Woll MG, Qi H, Turpoff A, et al. (2016) Discovery and optimization of small molecule splicing modifiers of survival motor neuron 2 (SMN2) as a treatment for spinal muscular atrophy. Journal of Medicinal Chemistry
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