Ellen Welch
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Publications
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Luban J, Sattler R, Mühlberger E, et al. (2020) The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines. Virus Research. 198246 |
Luban J, Sattler R, Mühlberger E, et al. (2020) The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines. Biorxiv : the Preprint Server For Biology |
Baiazitov RY, Friesen W, Johnson B, et al. (2020) Chemical modifications of G418 (geneticin): Synthesis of novel readthrough aminoglycosides results in an improved in vitro safety window but no improvements in vivo. Carbohydrate Research. 495: 108058 |
Kramerova I, Kumagai-Cresse C, Ermolova N, et al. (2019) Spp1 (osteopontin) promotes TGFβ processing in fibroblasts of dystrophin deficient muscles through matrix metalloproteinases. Human Molecular Genetics |
Ng MY, Zhang H, Weil A, et al. (2018) New Assay Measuring Direct Interaction of Nonsense Suppressors with the Eukaryotic Protein Synthesis Machinery. Acs Medicinal Chemistry Letters. 9: 1285-1291 |
Friesen WJ, Johnson B, Sierra J, et al. (2018) The minor gentamicin complex component, X2, is a potent premature stop codon readthrough molecule with therapeutic potential. Plos One. 13: e0206158 |
Friesen WJ, Trotta CR, Tomizawa Y, et al. (2017) The nucleoside analog clitocine is a potent and efficacious readthrough agent. Rna (New York, N.Y.) |
Roy B, Friesen WJ, Tomizawa Y, et al. (2016) Ataluren stimulates ribosomal selection of near-cognate tRNAs to promote nonsense suppression. Proceedings of the National Academy of Sciences of the United States of America |
Moosajee M, Tracey-White D, Smart M, et al. (2016) Functional rescue of REP1 following treatment with PTC124 and novel derivative PTC-414 in human choroideremia fibroblasts and the nonsense-mediated zebrafish model. Human Molecular Genetics |
Woll MG, Qi H, Turpoff A, et al. (2016) Discovery and optimization of small molecule splicing modifiers of survival motor neuron 2 (SMN2) as a treatment for spinal muscular atrophy. Journal of Medicinal Chemistry |