Frances Wiseman, MRes, PhD

Affiliations: 
2018- UCL Institute of Neurology, Queen Square, London, England, United Kingdom 
Area:
Ageing, Neuroscience, Down Syndrome, Alzheimer’s disease, Genetics
Website:
https://iris.ucl.ac.uk/iris/browse/profile?upi=FWISE73
Google:
"Frances Wiseman"
Bio:

Appointments
01-NOV-2018 – 31-OCT-2022, Alzheimer's Research UK Senior Fellow
Academic Background
2007, PhD, Doctor of Philosophy – Biomedical Sciences, University of Edinburgh
2003, MRes, Master of Research – Cell and Molecular Biology, University of Edinburgh
2002, BA, Bachelor of Arts – Biological Sciences, University of Oxford

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Publications

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Wu Y, Mumford P, Noy S, et al. (2023) Cathepsin B abundance, activity and microglial localisation in Alzheimer's disease-Down syndrome and early onset Alzheimer's disease; the role of elevated cystatin B. Acta Neuropathologica Communications. 11: 132
Mumford P, Tosh J, Anderle S, et al. (2022) Genetic mapping of APP and amyloid-β biology modulation by trisomy 21. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Farrell C, Mumford P, Wiseman FK. (2022) Rodent Modeling of Alzheimer's Disease in Down Syndrome: and Approaches. Frontiers in Neuroscience. 16: 909669
Cannavo C, Cleverley K, Maduro C, et al. (2022) Endosomal structure and APP biology are not altered in a preclinical mouse cellular model of Down syndrome. Plos One. 17: e0262558
Wu Y, West NR, Bhattacharyya A, et al. (2022) Cell models for Down syndrome-Alzheimer's disease research. Neuronal Signaling. 6: NS20210054
Wu Y, Whittaker HT, Noy S, et al. (2021) The effects of Cstb duplication on APP/amyloid-β pathology and cathepsin B activity in a mouse model. Plos One. 16: e0242236
Tosh JL, Rhymes ER, Mumford P, et al. (2021) Publisher Correction: Genetic dissection of down syndrome‑associated alterations in APP/amyloid‑β biology using mouse models. Scientific Reports. 11: 14966
Tosh JL, Rhymes ER, Mumford P, et al. (2021) Genetic dissection of down syndrome-associated alterations in APP/amyloid-β biology using mouse models. Scientific Reports. 11: 5736
Cannavo C, Tosh J, Fisher EMC, et al. (2020) Using mouse models to understand Alzheimer's disease mechanisms in the context of trisomy of chromosome 21. Progress in Brain Research. 251: 181-208
Wiseman FK. (2020) Understanding trisomy 21–associated alterations in APP/Amyloid‐β biology using mouse models Alzheimer's & Dementia. 16
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