Liyin Huang
Affiliations: | Duke University, Durham, NC |
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| Kahsai AW, Shah KS, Shim PJ, et al. (2023) Signal transduction at GPCRs: Allosteric activation of the ERK MAPK by β-arrestin. Proceedings of the National Academy of Sciences of the United States of America. 120: e2303794120 |
| Asher WB, Terry DS, Gregorio GGA, et al. (2022) GPCR-mediated β-arrestin activation deconvoluted with single-molecule precision. Cell |
| Zang Y, Kahsai AW, Pakharukova N, et al. (2021) The GPCR-β-arrestin complex allosterically activates C-Raf by binding its amino-terminus. The Journal of Biological Chemistry. 101369 |
| Nguyen AH, Thomsen ARB, Cahill TJ, et al. (2019) Structure of an endosomal signaling GPCR-G protein-β-arrestin megacomplex. Nature Structural & Molecular Biology |
| Liu X, Masoudi A, Kahsai AW, et al. (2019) Mechanism of βAR regulation by an intracellular positive allosteric modulator. Science (New York, N.Y.). 364: 1283-1287 |
| Liu X, Masoudi A, Kahsai AW, et al. (2019) Mechanism of beta2AR regulation by an intracellular positive allosteric modulator. Science. 364: 1283-1287 |
| Ahn S, Pani B, Kahsai AW, et al. (2018) Small Molecule Positive Allosteric Modulators of the β-Adrenoceptor Isolated from DNA Encoded Libraries. Molecular Pharmacology |
| Rein LA, Wisler JW, Kim J, et al. (2017) β-Arrestin2 mediates progression of murine primary myelofibrosis. Jci Insight. 2 |
| Cahill TJ, Thomsen AR, Tarrasch JT, et al. (2017) Distinct conformations of GPCR-β-arrestin complexes mediate desensitization, signaling, and endocytosis. Proceedings of the National Academy of Sciences of the United States of America |
| Thomsen AR, Plouffe B, Cahill TJ, et al. (2016) GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling. Cell |