Mika Scheinin

Affiliations: 
Duke University, Durham, NC 
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"Mika Scheinin"
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Pakkanen SA, Raekallio MR, Mykkänen AK, et al. (2014) Detomidine and the combination of detomidine and MK-467, a peripheral alpha-2 adrenoceptor antagonist, as premedication in horses anaesthetized with isoflurane. Veterinary Anaesthesia and Analgesia
Young S, Vainio M, Scheinin M, et al. (2010) Antinociceptive synergism of MD-354 and clonidine. Part II. The alpha-adrenoceptor component. Basic & Clinical Pharmacology & Toxicology. 107: 690-7
Rozwandowicz-Jansen A, Laurila J, Martikkala E, et al. (2010) Homogeneous GTP binding assay employing QRET technology. Journal of Biomolecular Screening. 15: 261-7
Gentili F, Cardinaletti C, Vesprini C, et al. (2008) Alpha2-adrenoreceptors profile modulation. 4. From antagonist to agonist behavior. Journal of Medicinal Chemistry. 51: 4289-99
Fagerholm V, Scheinin M, Haaparanta M. (2008) alpha2A-adrenoceptor antagonism increases insulin secretion and synergistically augments the insulinotropic effect of glibenclamide in mice. British Journal of Pharmacology. 154: 1287-96
Huhtinen A, Scheinin M. (2008) Expression and characterization of the human alpha 2B-adrenoceptor in a vascular smooth muscle cell line. European Journal of Pharmacology. 587: 48-56
Kurnik D, Muszkat M, Sofowora GG, et al. (2007) Ethnic and genetic determinants of cardiovascular response to the selective alpha 2-adrenoceptor agonist dexmedetomidine. Hypertension (Dallas, Tex. : 1979). 51: 406-11
Laurila JM, Xhaard H, Ruuskanen JO, et al. (2007) The second extracellular loop of alpha2A-adrenoceptors contributes to the binding of yohimbine analogues. British Journal of Pharmacology. 151: 1293-304
Snapir A, Posti J, Kentala E, et al. (2006) Effects of low and high plasma concentrations of dexmedetomidine on myocardial perfusion and cardiac function in healthy male subjects. Anesthesiology. 105: 902-10; quiz 1069-70
Ozdoğan UK, Lähdesmäki J, Scheinin M. (2006) The analgesic efficacy of partial opioid agonists is increased in mice with targeted inactivation of the alpha2A-adrenoceptor gene. European Journal of Pharmacology. 529: 105-13
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