Alessio Caruso

Affiliations: 
2016-2021 Chemistry Princeton University, Princeton, NJ 
 2021- Chemistry and Chemical Biology Harvard University, Cambridge, MA, United States 
Area:
chemistry, biochemistry, enzymology, structural biology
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"Alessio Caruso"
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Parents

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Catherine L. Drennan research assistant 2014-2015 MIT (Chemistry Tree)
Mohammad R. Seyedsayamdost grad student 2016-2021 Princeton (Chemistry Tree)
Daniel E. Kahne post-doc 2021- Harvard (Chemistry Tree)
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Publications

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Bushin LB, Covington BC, Clark KA, et al. (2022) Bicyclostreptins are radical SAM enzyme-modified peptides with unique cyclization motifs. Nature Chemical Biology
Caruso A, Seyedsayamdost MR. (2021) Radical SAM Enzyme QmpB Installs Two 9-Membered Ring Sactionine Macrocycles during Biogenesis of a Ribosomal Peptide Natural Product. The Journal of Organic Chemistry
Balo AR, Caruso A, Tao L, et al. (2021) Trapping a cross-linked lysine-tryptophan radical in the catalytic cycle of the radical SAM enzyme SuiB. Proceedings of the National Academy of Sciences of the United States of America. 118
Caruso A, Martinie RJ, Bushin LB, et al. (2019) Macrocyclization via an Arginine-Tyrosine Crosslink Broadens the Reaction Scope of Radical -Adenosylmethionine Enzymes. Journal of the American Chemical Society
Bowman SEJ, Backman LRF, Bjork RE, et al. (2019) Solution structure and biochemical characterization of a spare part protein that restores activity to an oxygen-damaged glycyl radical enzyme. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry
Caruso A, Bushin LB, Clark KA, et al. (2018) A Radical Approach to Enzymatic β-Thioether Bond Formation. Journal of the American Chemical Society
Schramma KR, Forneris CC, Caruso A, et al. (2018) Mechanistic Investigations of Lysine-Tryptophan Cross-Link Formation Catalyzed by Streptococcal Radical S-Adenosylmethionine Enzymes. Biochemistry. 57: 461-468
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