Alexandre Gaspar-Maia

Affiliations: 
Mayo Clinic, Rochester, MN, United States 
Area:
Epigenomics
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"Alexandre Gaspar-Maia"
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Parents

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Miguel R. Santos grad student 2004-2010 UCSF
Emily Bernstein post-doc 2010-2017 Mount Sinai School of Medicine (Chemistry Tree)

Children

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Wazim Mohammed Ismail post-doc 2020- Mayo Clinic
John W. Moore-Weiss post-doc 2021- Mayo Clinic (Physics Tree)
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Publications

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Mohammed Ismail W, Mazzone A, Ghiraldini FG, et al. (2023) MacroH2A histone variants modulate enhancer activity to repress oncogenic programs and cellular reprogramming. Communications Biology. 6: 215
Binder M, Carr RM, Lasho TL, et al. (2022) Oncogenic gene expression and epigenetic remodeling of cis-regulatory elements in ASXL1-mutant chronic myelomonocytic leukemia. Nature Communications. 13: 1434
Fang C, Wang Z, Han C, et al. (2020) Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation. Genome Biology. 21: 247
Safgren SL, Olson RLO, Vrabel AM, et al. (2020) The transcription factor GLI1 cooperates with the chromatin remodeler SMARCA2 to regulate chromatin accessibility at distal DNA regulatory elements. The Journal of Biological Chemistry
Sun Z, Filipescu D, Andrade J, et al. (2018) Transcription-associated histone pruning demarcates macroH2A chromatin domains. Nature Structural & Molecular Biology. 25: 958-970
Chung CY, Sun Z, Mullokandov G, et al. (2016) Cbx8 Acts Non-canonically with Wdr5 to Promote Mammary Tumorigenesis. Cell Reports
Vardabasso C, Gaspar-Maia A, Hasson D, et al. (2015) Histone Variant H2A.Z.2 Mediates Proliferation and Drug Sensitivity of Malignant Melanoma. Molecular Cell. 59: 75-88
Vardabasso C, Gaspar-Maia A, Punzeler S, et al. (2015) Abstract A12: Histone variant H2A.Z.2 mediates proliferation and drug sensitivity of malignant melanoma Cancer Research. 75
Gaspar-Maia A, Qadeer ZA, Hasson D, et al. (2013) MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency. Nature Communications. 4: 1565
Chung C, Gaspar-Maia A, Mullokandov G, et al. (2013) Abstract A021: Loss-of-function screen for breast tumor initiating cells reveals PRC1 dependence Molecular Cancer Research. 11
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