Christopher Patzke
Affiliations: | 2020- | Department of Biological Sciences | University of Notre Dame, Notre Dame, IN, United States |
Area:
Neuroscience, Synapse, Cell BiologyGoogle:
"Christopher Patzke"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Fritz G. Rathjen | grad student | Max Delbruck Center for Molecular Medicine, Berlin | |
| Thomas C. Sudhof | post-doc | 2012-2020 | Stanford University Medical School |
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Publications
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| Dai J, Patzke C, Liakath-Ali K, et al. (2021) GluD1 is a signal transduction device disguised as an ionotropic receptor. Nature. 595: 261-265 |
| Patzke C, Dai J, Brockmann MM, et al. (2021) Cannabinoid receptor activation acutely increases synaptic vesicle numbers by activating synapsins in human synapses. Molecular Psychiatry |
| Mencacci NE, Brockmann MM, Dai J, et al. (2021) Bi-allelic variants in TSPOAP1, encoding the active zone protein RIMBP1, cause autosomal recessive dystonia. The Journal of Clinical Investigation |
| Patzke C, Brockmann MM, Dai J, et al. (2019) Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses. Cell. 179: 498-513.e22 |
| Zhang Z, Marro SG, Zhang Y, et al. (2018) The fragile X mutation impairs homeostatic plasticity in human neurons by blocking synaptic retinoic acid signaling. Science Translational Medicine. 10 |
| Patzke C, Südhof TC. (2016) The conditional KO approach: Cre/Lox technology in human neurons. Rare Diseases (Austin, Tex.). 4: e1131884 |
| Patzke C, Acuna C, Giam LR, et al. (2016) Conditional deletion of L1CAM in human neurons impairs both axonal and dendritic arborization and action potential generation. The Journal of Experimental Medicine. 213: 499-515 |
| Yi F, Danko T, Botelho SC, et al. (2016) Autism-associated SHANK3 haploinsufficiency causes Ih channelopathy in human neurons. Science (New York, N.Y.). 352: aaf2669 |
| Patzke C, Han Y, Covy J, et al. (2015) Analysis of conditional heterozygous STXBP1 mutations in human neurons. The Journal of Clinical Investigation. 125: 3560-71 |
| Zhang Y, Pak C, Han Y, et al. (2013) Rapid single-step induction of functional neurons from human pluripotent stem cells. Neuron. 78: 785-98 |