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Henry M. Furneaux

Affiliations: 
Molecular Biology & Biochemistry University of Connecticut Health Center, Farmington, CT, United States 
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"Henry Furneaux"
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Cross-listing: Chemistry Tree

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Parents

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Jerard Hurwitz post-doc Memorial Sloan Kettering Cancer Center (Chemistry Tree)

Children

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David W. Salzman grad student 2004-2009 University of Connecticut Health Center

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Publications

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Felice KM, Salzman DW, Shubert-Coleman J, et al. (2009) The 5' terminal uracil of let-7a is critical for the recruitment of mRNA to Argonaute2. The Biochemical Journal. 422: 329-41
Salzman DW, Shubert-Coleman J, Furneaux H. (2007) P68 RNA helicase unwinds the human let-7 microRNA precursor duplex and is required for let-7-directed silencing of gene expression. The Journal of Biological Chemistry. 282: 32773-9
Abdelmohsen K, Pullmann R, Lal A, et al. (2007) Phosphorylation of HuR by Chk2 regulates SIRT1 expression. Molecular Cell. 25: 543-57
Sengupta S, Jang BC, Wu MT, et al. (2003) The RNA-binding protein HuR regulates the expression of cyclooxygenase-2. The Journal of Biological Chemistry. 278: 25227-33
Giles KM, Daly JM, Beveridge DJ, et al. (2003) The 3'-untranslated region of p21WAF1 mRNA is a composite cis-acting sequence bound by RNA-binding proteins from breast cancer cells, including HuR and poly(C)-binding protein. The Journal of Biological Chemistry. 278: 2937-46
Yeap BB, Voon DC, Vivian JP, et al. (2002) Novel binding of HuR and poly(C)-binding protein to a conserved UC-rich motif within the 3'-untranslated region of the androgen receptor messenger RNA. The Journal of Biological Chemistry. 277: 27183-92
Cuadrado A, Navarro-Yubero C, Furneaux H, et al. (2002) HuD binds to three AU-rich sequences in the 3'-UTR of neuroserpin mRNA and promotes the accumulation of neuroserpin mRNA and protein. Nucleic Acids Research. 30: 2202-11
Mobarak CD, Anderson KD, Morin M, et al. (2000) The RNA-binding protein HuD is required for GAP-43 mRNA stability, GAP-43 gene expression, and PKC-dependent neurite outgrowth in PC12 cells. Molecular Biology of the Cell. 11: 3191-203
Zhao Z, Chang FC, Furneaux HM. (2000) The identification of an endonuclease that cleaves within an HuR binding site in mRNA Nucleic Acids Research. 28: 2695-2701
Rodriguez-Pascual F, Hausding M, Ihrig-Biedert I, et al. (2000) Complex contribution of the 3'-untranslated region to the expressional regulation of the human inducible nitric-oxide synthase gene. Involvement of the RNA-binding protein HuR. The Journal of Biological Chemistry. 275: 26040-9
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