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Anthony Y.H. Lu, PhD

Affiliations: 
Chemical Biology Rutgers University, New Brunswick, New Brunswick, NJ, United States 
Area:
drug metabolism, P450 cytochromes, drug discovery
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"Anthony Lu"
Mean distance: 18.23 (cluster 58)
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Parents

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Minor J. Coon post-doc University of Michigan

Children

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Alexandru D.P. Papoiu post-doc 2001-2002 Rutgers, New Brunswick

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Publications

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Khojasteh SC, Prabhu S, Kenny JR, et al. (2011) Chemical inhibitors of cytochrome P450 isoforms in human liver microsomes: a re-evaluation of P450 isoform selectivity. European Journal of Drug Metabolism and Pharmacokinetics. 36: 1-16
Shou M, Lu AY. (2009) Antibodies as a probe in cytochrome P450 research. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 925-31
Ma Q, Lu AY. (2008) The challenges of dealing with promiscuous drug-metabolizing enzymes, receptors and transporters. Current Drug Metabolism. 9: 374-83
Ma Q, Lu AY. (2007) CYP1A induction and human risk assessment: an evolving tale of in vitro and in vivo studies. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 1009-16
Tang W, Wang RW, Lu AY. (2005) Utility of recombinant cytochrome p450 enzymes: a drug metabolism perspective. Current Drug Metabolism. 6: 503-17
Tang C, Lin JH, Lu AY. (2005) Metabolism-based drug-drug interactions: what determines individual variability in cytochrome P450 induction? Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 603-13
He XY, Shen J, Ding X, et al. (2004) Identification of critical amino acid residues of human CYP2A13 for the metabolic activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco-specific carcinogen. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 1516-21
Lu AY, Wang RW, Lin JH. (2003) Cytochrome P450 in vitro reaction phenotyping: a re-evaluation of approaches used for P450 isoform identification. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 31: 345-50
Lu AY. (1998) The 1996 Bernard B. Brodie lecture: A journey in cytochrome P450 and drug metabolism research. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 26: 1168-73
Lin JH, Lu AY. (1998) Inhibition and induction of cytochrome P450 and the clinical implications. Clinical Pharmacokinetics. 35: 361-90
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