Melissa K. McCoy
Affiliations: | 2002-2007 | Physiology | HHMI/UT Southwestern Medical Center |
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Parents
Sign in to add mentor| Malu G Tansey | grad student | 2002-2007 | HHMI/UT Southwestern Medical Center |
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Publications
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| McCoy MK, Ruhn KA, Blesch A, et al. (2011) TNF: a key neuroinflammatory mediator of neurotoxicity and neurodegeneration in models of Parkinson's disease. Advances in Experimental Medicine and Biology. 691: 539-40 |
| McCoy MK, Tansey MG. (2008) TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease. Journal of Neuroinflammation. 5: 45 |
| Lee JK, McCoy MK, Harms AS, et al. (2008) Regulator of G-protein signaling 10 promotes dopaminergic neuron survival via regulation of the microglial inflammatory response. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 8517-28 |
| McCoy MK, Ruhn KA, Martinez TN, et al. (2008) Intranigral lentiviral delivery of dominant-negative TNF attenuates neurodegeneration and behavioral deficits in hemiparkinsonian rats. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1572-9 |
| Tran TA, McCoy MK, Sporn MB, et al. (2008) The synthetic triterpenoid CDDO-methyl ester modulates microglial activities, inhibits TNF production, and provides dopaminergic neuroprotection. Journal of Neuroinflammation. 5: 14 |
| McCoy MK, Martinez TN, Ruhn KA, et al. (2008) Autologous transplants of Adipose-Derived Adult Stromal (ADAS) cells afford dopaminergic neuroprotection in a model of Parkinson's disease. Experimental Neurology. 210: 14-29 |
| Tansey MG, Frank-Cannon TC, McCoy MK, et al. (2008) Neuroinflammation in Parkinson's disease: is there sufficient evidence for mechanism-based interventional therapy? Frontiers in Bioscience : a Journal and Virtual Library. 13: 709-17 |
| Tansey MG, McCoy MK, Frank-Cannon TC. (2007) Neuroinflammatory mechanisms in Parkinson's disease: potential environmental triggers, pathways, and targets for early therapeutic intervention. Experimental Neurology. 208: 1-25 |
| McCoy MK, Martinez TN, Ruhn KA, et al. (2006) Blocking soluble tumor necrosis factor signaling with dominant-negative tumor necrosis factor inhibitor attenuates loss of dopaminergic neurons in models of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 9365-75 |