Thomas E. Mahan
Affiliations: | Washington University in St. Louis, School of Medicine |
Area:
Alzheimer disease, Down syndromeGoogle:
"Thomas Mahan"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| David M. Holtzman | grad student | 2014-2021 | Washington University in St. Louis, School of Medicine |
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Publications
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| Mahan TE, Wang C, Bao X, et al. (2022) Selective reduction of astrocyte apoE3 and apoE4 strongly reduces Aβ accumulation and plaque-related pathology in a mouse model of amyloidosis. Molecular Neurodegeneration. 17: 13 |
| Lall D, Lorenzini I, Mota TA, et al. (2021) C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation. Neuron |
| Huynh TV, Wang C, Tran AC, et al. (2019) Lack of hepatic apoE does not influence early Aβ deposition: observations from a new APOE knock-in model. Molecular Neurodegeneration. 14: 37 |
| Holth JK, Fritschi SK, Wang C, et al. (2019) The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans. Science (New York, N.Y.) |
| Lessard CB, Malnik SL, Zhou Y, et al. (2018) High-affinity interactions and signal transduction between Aβ oligomers and TREM2. Embo Molecular Medicine |
| Ulrich JD, Ulland TK, Mahan TE, et al. (2018) ApoE facilitates the microglial response to amyloid plaque pathology. The Journal of Experimental Medicine |
| Huynh TV, Liao F, Francis CM, et al. (2017) Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis. Neuron. 96: 1013-1023.e4 |
| Holth JK, Mahan TE, Robinson GO, et al. (2017) Altered sleep and EEG power in the P301S Tau transgenic mouse model. Annals of Clinical and Translational Neurology. 4: 180-190 |
| Wang Y, Ulland TK, Ulrich JD, et al. (2016) TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques. The Journal of Experimental Medicine |
| Yamada K, Patel TK, Hochgräfe K, et al. (2015) Analysis of in vivo turnover of tau in a mouse model of tauopathy. Molecular Neurodegeneration. 10: 55 |