Thomas E. Nielsen
Affiliations: | Novo Nordisk A/S, Denmark |
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| Flagstad T, Pedersen MT, Jakobsen TH, et al. (2021) Solid-phase synthesis and biological evaluation of piperazine-based novel bacterial topoisomerase inhibitors. Bioorganic & Medicinal Chemistry Letters. 57: 128499 |
| Wu P, Givskov M, Nielsen TE. (2019) Reactivity and Synthetic Applications of Multicomponent Petasis Reactions. Chemical Reviews |
| Wu P, Nielsen TE. (2018) Petasis three-component reactions for the synthesis of diverse heterocyclic scaffolds. Drug Discovery Today. Technologies. 29: 27-33 |
| Bang C, Jensen J, Cohrt E, et al. (2017) Solid-Phase Synthesis of Hydroxamic Acids and Identification of HDAC Inhibitors Using a Chemi-luminescence-based Assay. Acs Combinatorial Science |
| Ishoey M, Petersen RG, Petersen MÅ, et al. (2017) Diastereoselective synthesis of novel heterocyclic scaffolds through tandem Petasis 3-component/intramolecular Diels-Alder and ROM-RCM reactions. Chemical Communications (Cambridge, England) |
| Wu P, Nielsen TE. (2017) Scaffold Diversity from N-Acyliminium Ions. Chemical Reviews |
| Hansen CL, Ohm RG, Olsen LB, et al. (2016) Catalytic Enantioselective Synthesis of Tetrahydocarbazoles and Exocyclic Pictet-Spengler-Type Reactions. Organic Letters. 18: 5990-5993 |
| Wu P, Petersen MÅ, Cohrt AE, et al. (2016) A metal-catalyzed enyne-cyclization step for the synthesis of bi- and tricyclic scaffolds amenable to molecular library production. Organic & Biomolecular Chemistry |
| Wu P, Clausen MH, Nielsen TE. (2015) Allosteric small-molecule kinase inhibitors. Pharmacology & Therapeutics |
| Wu P, Nielsen TE, Clausen MH. (2015) Small-molecule kinase inhibitors: an analysis of FDA-approved drugs. Drug Discovery Today |