Vicki L. Coffin
Affiliations: | Ross University School of Medicine |
Area:
Adenosine, dopamine, dopamine D1 receptors, NK1 antagonist, muscarinic M2 antagonist, caffeine, adenosine antagonistGoogle:
"Vicki Coffin"Mean distance: 18.34 (cluster 19) | S | N | B | C | P |
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Publications
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| Varty GB, Lu SX, Morgan CA, et al. (2008) The anxiolytic-like effects of the novel, orally active nociceptin opioid receptor agonist 8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol (SCH 221510). The Journal of Pharmacology and Experimental Therapeutics. 326: 672-82 |
| Shue HJ, Chen X, Schwerdt JH, et al. (2006) Cyclic urea derivatives as potent NK1 selective antagonists. Part II: Effects of fluoro and benzylic methyl substitutions. Bioorganic & Medicinal Chemistry Letters. 16: 1065-9 |
| Shue HJ, Chen X, Shih NY, et al. (2005) Cyclic urea derivatives as potent NK1 selective antagonists. Bioorganic & Medicinal Chemistry Letters. 15: 3896-9 |
| Wang Y, Chackalamannil S, Hu Z, et al. (2002) Improving the oral efficacy of CNS drug candidates: discovery of highly orally efficacious piperidinyl piperidine M2 muscarinic receptor antagonists. Journal of Medicinal Chemistry. 45: 5415-8 |
| Boyle CD, Vice SF, Campion J, et al. (2002) Enhancement of pharmacokinetic properties and in vivo efficacy of benzylidene ketal M(2) muscarinic receptor antagonists via benzamide modification. Bioorganic & Medicinal Chemistry Letters. 12: 3479-82 |
| Varty GB, Cohen-Williams ME, Morgan CA, et al. (2002) The gerbil elevated plus-maze II: anxiolytic-like effects of selective neurokinin NK1 receptor antagonists. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 27: 371-9 |
| Varty GB, Morgan CA, Cohen-Williams ME, et al. (2002) The gerbil elevated plus-maze I: behavioral characterization and pharmacological validation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 27: 357-70 |
| Carey GJ, Billard W, Binch H, et al. (2001) SCH 57790, a selective muscarinic M(2) receptor antagonist, releases acetylcholine and produces cognitive enhancement in laboratory animals. European Journal of Pharmacology. 431: 189-200 |
| Boyle CD, Chackalamannil S, Clader JW, et al. (2001) Metabolic stabilization of benzylidene ketal M(2) muscarinic receptor antagonists via halonaphthoic acid substitution. Bioorganic & Medicinal Chemistry Letters. 11: 2311-4 |
| Greenlee W, Clader J, Asberom T, et al. (2001) Muscarinic agonists and antagonists in the treatment of Alzheimer's disease. Farmaco (Societã Chimica Italiana : 1989). 56: 247-50 |