Derek S. Tan, PhD
Affiliations: | 2002- | Chemical Biology | Memorial Sloan Kettering Cancer Center, Rockville Centre, NY, United States |
Area:
organic synthesis, chemical biologyWebsite:
http://www.mskcc.org/tanGoogle:
"Derek Tan"Mean distance: 7.32 | S | N | B | C | P |
Parents
Sign in to add mentor| Dale Gene Drueckhammer | research assistant | 1993-1995 | Stanford | |
| (Undergraduate) | ||||
| David A. Oare | research assistant | 1995-1995 | Genentech, Inc. | |
| (Summer intern) | ||||
| Stuart L. Schreiber | grad student | 1995-2000 | Harvard | |
| (Diversity-oriented synthesis targeted to chemical genetics) | ||||
| Samuel J. Danishefsky | post-doc | 2000-2002 | Memorial Sloan Kettering Cancer Center | |
| (Total synthesis of guanacastepene) | ||||
Children
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BETA: Related publications
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Publications
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| Leus IV, Adamiak J, Chandar B, et al. (2023) Functional Diversity of Gram-Negative Permeability Barriers Reflected in Antibacterial Activities and Intracellular Accumulation of Antibiotics. Antimicrobial Agents and Chemotherapy. e0137722 |
| Gardner TJ, Lee JP, Bourne CM, et al. (2021) Engineering CAR-T cells to activate small-molecule drugs in situ. Nature Chemical Biology |
| Kinarivala N, Standke LC, Guney T, et al. (2020) Gram-scale preparation of the antibiotic lead compound salicyl-AMS, a potent inhibitor of bacterial salicylate adenylation enzymes. Methods in Enzymology. 638: 69-87 |
| Xu Y, Tan DS. (2019) Total Synthesis of the Bacterial Diisonitrile Chalkophore SF2768. Organic Letters |
| Minuesa G, Albanese SK, Xie W, et al. (2019) Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia. Nature Communications. 10: 2691 |
| Lux MC, Boby ML, Brooks JL, et al. (2019) Synthesis of bicyclic ethers by a palladium-catalyzed oxidative cyclization-redox relay-π-allyl-Pd cyclization cascade reaction. Chemical Communications (Cambridge, England) |
| Ji C, Sharma I, Pratihar D, et al. (2019) Designed Small-Molecule Inhibitors of the Anthranilyl-CoA Synthetase PqsA Block Quinolone Biosynthesis in Pseudomonas aeruginosa. Acs Chemical Biology |
| Lux MC, Standke LC, Tan DS. (2019) Targeting adenylate-forming enzymes with designed sulfonyladenosine inhibitors. The Journal of Antibiotics |
| Evans CE, Si Y, Matarlo JS, et al. (2019) Structure-Based Design, Synthesis, and Biological Evaluation of Non-Acyl Sulfamate Inhibitors of the Adenylate-Forming Enzyme MenE. Biochemistry |
| Kearney SE, Zahoránszky-Kőhalmi G, Brimacombe KR, et al. (2018) Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space. Acs Central Science. 4: 1727-1741 |