Year |
Citation |
Score |
2021 |
Mathiharan YK, Glaaser IW, Zhao Y, Robertson MJ, Skiniotis G, Slesinger PA. Structural insights into GIRK2 channel modulation by cholesterol and PIP. Cell Reports. 36: 109619. PMID 34433062 DOI: 10.1016/j.celrep.2021.109619 |
0.41 |
|
2021 |
Zhao Y, Gameiro-Ros I, Glaaser IW, Slesinger PA. Advances in Targeting GIRK Channels in Disease. Trends in Pharmacological Sciences. 42: 203-215. PMID 33468322 DOI: 10.1016/j.tips.2020.12.002 |
0.367 |
|
2020 |
Zhao Y, Ung PM, Zahoránszky-Kőhalmi G, Zakharov AV, Martinez NJ, Simeonov A, Glaaser IW, Rai G, Schlessinger A, Marugan JJ, Slesinger PA. Identification of a G-Protein-Independent Activator of GIRK Channels. Cell Reports. 31: 107770. PMID 32553165 DOI: 10.1016/J.Celrep.2020.107770 |
0.46 |
|
2020 |
Glaaser IW, Mathiharan YK, Zhao Y, Skiniotis G, Slesinger PA. CRYO-EM Structures of the GIRK2 Channel Reveal Mechanisms for Lipid Modulation Biophysical Journal. 118: 497a-498a. DOI: 10.1016/J.Bpj.2019.11.2749 |
0.523 |
|
2017 |
Lacin E, Aryal P, Glaaser IW, Bodhinathan K, Tsai E, Marsh N, Tucker SJ, Sansom MSP, Slesinger PA. Dynamic role of the tether helix in PIP2-dependent gating of a G protein-gated potassium channel. The Journal of General Physiology. PMID 28720589 DOI: 10.1085/Jgp.201711801 |
0.515 |
|
2017 |
Glaaser IW, Slesinger PA. Dual activation of neuronal G protein-gated inwardly rectifying potassium (GIRK) channels by cholesterol and alcohol. Scientific Reports. 7: 4592. PMID 28676630 DOI: 10.1038/S41598-017-04681-X |
0.4 |
|
2017 |
Glaaser IW, Slesinger PA. Small Molecule Modulation of Brain GIRK Channels Biophysical Journal. 112: 182a-183a. DOI: 10.1016/J.Bpj.2016.11.1012 |
0.45 |
|
2015 |
Glaaser IW, Slesinger PA. Structural Insights into GIRK Channel Function. International Review of Neurobiology. 123: 117-60. PMID 26422984 DOI: 10.1016/Bs.Irn.2015.05.014 |
0.524 |
|
2015 |
Glaaser IW, Marsh NO, Choe S, Slesinger PA. Alcohol Inhibition of a Chemically-Activated GIRK2 Channel Biophysical Journal. 108: 367a. DOI: 10.1016/J.Bpj.2014.11.2013 |
0.352 |
|
2012 |
Glaaser IW, Osteen JD, Puckerin A, Sampson KJ, Jin X, Kass RS. Perturbation of sodium channel structure by an inherited Long QT Syndrome mutation. Nature Communications. 3: 706. PMID 22426227 DOI: 10.1038/Ncomms1717 |
0.746 |
|
2011 |
Glaaser IW, Osteen JD, Puckerin A, Kass RS. Mapping the Structure of the Cardiac Voltage-Gated Sodium Channel (Nav1.5) C-Terminus: Implications of An Lqt3 Mutant Biophysical Journal. 100: 15a. DOI: 10.1016/J.Bpj.2010.12.293 |
0.717 |
|
2008 |
Holland KD, Kearney JA, Glauser TA, Buck G, Keddache M, Blankston JR, Glaaser IW, Kass RS, Meisler MH. Mutation of sodium channel SCN3A in a patient with cryptogenic pediatric partial epilepsy. Neuroscience Letters. 433: 65-70. PMID 18242854 DOI: 10.1016/J.Neulet.2007.12.064 |
0.668 |
|
2007 |
Bankston JR, Sampson KJ, Kateriya S, Glaaser IW, Malito DL, Chung WK, Kass RS. A novel LQT-3 mutation disrupts an inactivation gate complex with distinct rate-dependent phenotypic consequences. Channels (Austin, Tex.). 1: 273-80. PMID 18708744 DOI: 10.4161/Chan.4956 |
0.748 |
|
2007 |
Kass RS, Cormier JW, Glaaser IW. The Cardiac Sodium-Channel Carboxy Terminus: Predicted and Detected Structure Provide a Novel Target For Antiarrhythmic Drugs Development New Arrhythmia Technologies. 36-47. DOI: 10.1002/9780470988725.ch4 |
0.717 |
|
2006 |
Glaaser IW, Bankston JR, Liu H, Tateyama M, Kass RS. A carboxyl-terminal hydrophobic interface is critical to sodium channel function. Relevance to inherited disorders. The Journal of Biological Chemistry. 281: 24015-23. PMID 16798729 DOI: 10.1074/Jbc.M605473200 |
0.764 |
|
2006 |
Glaaser IW, Clancy CE. Cardiac Na+ channels as therapeutic targets for antiarrhythmic agents. Handbook of Experimental Pharmacology. 99-121. PMID 16610342 DOI: 10.1007/3-540-29715-4_4 |
0.604 |
|
2005 |
Lam AD, Chikina MD, McNulty MM, Glaaser IW, Hanck DA. Role of Domain IV/S4 outermost arginines in gating of T-type calcium channels. Pflã¼Gers Archiv : European Journal of Physiology. 451: 349-61. PMID 16133267 DOI: 10.1007/S00424-005-1407-5 |
0.474 |
|
2004 |
Sunami A, Tracey A, Glaaser IW, Lipkind GM, Hanck DA, Fozzard HA. Accessibility of mid-segment domain IV S6 residues of the voltage-gated Na+ channel to methanethiosulfonate reagents. The Journal of Physiology. 561: 403-13. PMID 15579536 DOI: 10.1113/jphysiol.2004.067579 |
0.518 |
|
2004 |
Sandtner W, Szendroedi J, Zarrabi T, Zebedin E, Hilber K, Glaaser I, Fozzard HA, Dudley SC, Todt H. Lidocaine: A foot in the door of the inner vestibule prevents ultra-slow inactivation of a voltage-gated sodium channel Molecular Pharmacology. 66: 648-657. PMID 15322257 DOI: 10.1124/Mol.66.3 |
0.541 |
|
2004 |
Motoike HK, Liu H, Glaaser IW, Yang AS, Tateyama M, Kass RS. The Na+ channel inactivation gate is a molecular complex: a novel role of the COOH-terminal domain. The Journal of General Physiology. 123: 155-65. PMID 14744988 DOI: 10.1085/Jgp.200308929 |
0.731 |
|
2003 |
Glaaser IW, Kass RS, Clancy CE. Mechanisms of genetic arrhythmias: from DNA to ECG. Progress in Cardiovascular Diseases. 46: 259-70. PMID 14685943 DOI: 10.1016/S0033-0620(03)00073-2 |
0.591 |
|
2003 |
Bai CX, Glaaser IW, Sawanobori T, Sunami A. Involvement of local anesthetic binding sites on IVS6 of sodium channels in fast and slow inactivation. Neuroscience Letters. 337: 41-5. PMID 12524167 DOI: 10.1016/S0304-3940(02)01288-0 |
0.424 |
|
2002 |
Hilber K, Sandtner W, Kudlacek O, Schreiner B, Glaaser I, Schütz W, Fozzard HA, Dudley SC, Todt H. Interaction between fast and ultra-slow inactivation in the voltage-gated sodium channel. Does the inactivation gate stabilize the channel structure? Journal of Biological Chemistry. 277: 37105-37115. PMID 12138168 DOI: 10.1074/jbc.M205661200 |
0.534 |
|
2001 |
Hilber K, Sandtner W, Kudlacek O, Glaaser IW, Weisz E, Kyle JW, French RJ, Fozzard HA, Dudley SC, Todt H. The selectivity filter of the voltage-gated sodium channel is involved in channel activation. The Journal of Biological Chemistry. 276: 27831-9. PMID 11382756 DOI: 10.1074/jbc.M101933200 |
0.504 |
|
2001 |
Sunami A, Glaaser IW, Fozzard HA. Structural and gating changes of the sodium channel induced by mutation of a residue in the upper third of IVS6, creating an external access path for local anesthetics. Molecular Pharmacology. 59: 684-91. PMID 11259611 |
0.401 |
|
2000 |
Sunami A, Glaaser IW, Fozzard HA. A critical residue for isoform difference in tetrodotoxin affinity is a molecular determinant of the external access path for local anesthetics in the cardiac sodium channel. Proceedings of the National Academy of Sciences of the United States of America. 97: 2326-31. PMID 10681444 DOI: 10.1073/pnas.030438797 |
0.521 |
|
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