| Year |
Citation |
Score |
| 2016 |
Griebel G, Pichat P, Boulay D, Naimoli V, Potestio L, Featherstone R, Sahni S, Defex H, Desvignes C, Slowinski F, Vigé X, Bergis OE, Sher R, Kosley R, Kongsamut S, ... ... Varty GB, et al. The mGluR2 positive allosteric modulator, SAR218645, improves memory and attention deficits in translational models of cognitive symptoms associated with schizophrenia. Scientific Reports. 6: 35320. PMID 27734956 DOI: 10.1038/Srep35320 |
0.665 |
|
| 2014 |
Hodgson RA, Mullins D, Lu SX, Guzzi M, Zhang X, Bleickardt CJ, Scott JD, Miller MW, Stamford AW, Parker EM, Varty GB. Characterization of a novel vasopressin V1b receptor antagonist, V1B-30N, in animal models of anxiety-like and depression-like behavior. European Journal of Pharmacology. 730: 157-63. PMID 24602808 DOI: 10.1016/j.ejphar.2014.02.027 |
0.303 |
|
| 2012 |
Griebel G, Pichat P, Pruniaux MP, Beeské S, Lopez-Grancha M, Genet E, Terranova JP, Castro A, Sánchez JA, Black M, Varty GB, Weiner I, Arad M, Barak S, De Levie A, et al. SAR110894, a potent histamine H₃-receptor antagonist, displays procognitive effects in rodents. Pharmacology, Biochemistry, and Behavior. 102: 203-14. PMID 22542742 DOI: 10.1016/J.Pbb.2012.04.004 |
0.339 |
|
| 2011 |
Lu SX, Higgins GA, Hodgson RA, Hyde LA, Del Vecchio RA, Guthrie DH, Kazdoba T, McCool MF, Morgan CA, Bercovici A, Ho GD, Tulshian D, Parker EM, Hunter JC, Varty GB. The anxiolytic-like profile of the nociceptin receptor agonist, endo-8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octane-3-carboxamide (SCH 655842): comparison of efficacy and side effects across rodent species. European Journal of Pharmacology. 661: 63-71. PMID 21545797 DOI: 10.1016/j.ejphar.2011.04.034 |
0.346 |
|
| 2011 |
Black MD, Stevens RJ, Rogacki N, Featherstone RE, Senyah Y, Giardino O, Borowsky B, Stemmelin J, Cohen C, Pichat P, Arad M, Barak S, De Levie A, Weiner I, Griebel G, ... Varty GB, et al. AVE1625, a cannabinoid CB1 receptor antagonist, as a co-treatment with antipsychotics for schizophrenia: improvement in cognitive function and reduction of antipsychotic-side effects in rodents. Psychopharmacology. 215: 149-63. PMID 21181124 DOI: 10.1007/S00213-010-2124-0 |
0.401 |
|
| 2011 |
Rogacki N, Lopez-Grancha M, Naimoli V, Potestio L, Stevens RJ, Pichat P, Bergis OE, Cohen C, Varty GB, Griebel G. The neurokinin NK2 antagonist, saredutant, ameliorates stress-induced conditions without impairing cognition. Pharmacology, Biochemistry, and Behavior. 98: 405-11. PMID 21115031 DOI: 10.1016/J.Pbb.2010.11.017 |
0.661 |
|
| 2010 |
Xiao D, Wang C, Palani A, Tsui HC, Reichard G, Paliwal S, Shih NY, Aslanian R, Duffy R, Lachowicz J, Varty G, Morgan C, Liu F, Nomeir A. Discovery of a series of potent, orally active α,α-disubstituted piperidine NK(1) antagonists. Bioorganic & Medicinal Chemistry Letters. 20: 6313-5. PMID 20846861 DOI: 10.1016/J.Bmcl.2010.08.059 |
0.307 |
|
| 2009 |
Yang SW, Ho G, Tulshian D, Greenlee WJ, Tan Z, Zhang H, Smith-Torhan A, Fawzi A, Anthes J, Lu S, Varty G, Fernandez X, McLeod RL, Hey J. Identification of 3-substituted N-benzhydryl-nortropane analogs as nociceptin receptor ligands for the management of cough and anxiety. Bioorganic & Medicinal Chemistry Letters. 19: 2482-6. PMID 19332374 DOI: 10.1016/J.Bmcl.2009.03.057 |
0.304 |
|
| 2009 |
Bleickardt CJ, Mullins DE, Macsweeney CP, Werner BJ, Pond AJ, Guzzi MF, Martin FD, Varty GB, Hodgson RA. Characterization of the V1a antagonist, JNJ-17308616, in rodent models of anxiety-like behavior. Psychopharmacology. 202: 711-8. PMID 18923820 DOI: 10.1007/s00213-008-1354-x |
0.334 |
|
| 2009 |
Black MD, Varty GB, Arad M, Barak S, De Levie A, Boulay D, Pichat P, Griebel G, Weiner I. Procognitive and antipsychotic efficacy of glycine transport 1 inhibitors (GlyT1) in acute and neurodevelopmental models of schizophrenia: latent inhibition studies in the rat. Psychopharmacology. 202: 385-96. PMID 18709358 DOI: 10.1007/S00213-008-1289-2 |
0.338 |
|
| 2008 |
Varty GB, Hodgson RA, Pond AJ, Grzelak ME, Parker EM, Hunter JC. The effects of adenosine A2A receptor antagonists on haloperidol-induced movement disorders in primates. Psychopharmacology. 200: 393-401. PMID 18594798 DOI: 10.1007/s00213-008-1214-8 |
0.333 |
|
| 2008 |
Varty GB, Lu SX, Morgan CA, Cohen-Williams ME, Hodgson RA, Smith-Torhan A, Zhang H, Fawzi AB, Graziano MP, Ho GD, Matasi J, Tulshian D, Coffin VL, Carey GJ. The anxiolytic-like effects of the novel, orally active nociceptin opioid receptor agonist 8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol (SCH 221510). The Journal of Pharmacology and Experimental Therapeutics. 326: 672-82. PMID 18492950 DOI: 10.1124/Jpet.108.136937 |
0.337 |
|
| 2006 |
Varty GB, Powell SB, Lehmann-Masten V, Buell MR, Geyer MA. Isolation rearing of mice induces deficits in prepulse inhibition of the startle response. Behavioural Brain Research. 169: 162-7. PMID 16406103 DOI: 10.1016/J.Bbr.2005.11.025 |
0.644 |
|
| 2005 |
Varty GB, Hyde LA, Hodgson RA, Lu SX, McCool MF, Kazdoba TM, Del Vecchio RA, Guthrie DH, Pond AJ, Grzelak ME, Xu X, Korfmacher WA, Tulshian D, Parker EM, Higgins GA. Characterization of the nociceptin receptor (ORL-1) agonist, Ro64-6198, in tests of anxiety across multiple species. Psychopharmacology. 182: 132-43. PMID 16025321 DOI: 10.1007/s00213-005-0041-4 |
0.359 |
|
| 2004 |
Tagat JR, McCombie SW, Nazareno D, Labroli MA, Xiao Y, Steensma RW, Strizki JM, Baroudy BM, Cox K, Lachowicz J, Varty G, Watkins R. Piperazine-based CCR5 antagonists as HIV-1 inhibitors. IV. Discovery of 1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]- 4-[4-[2-methoxy-1(R)-4-(trifluoromethyl)phenyl]ethyl-3(S)-methyl-1-piperazinyl]- 4-methylpiperidine (Sch-417690/Sch-D), a potent, highly selective, and orally bioavailable CCR5 antagonist. Journal of Medicinal Chemistry. 47: 2405-8. PMID 15115380 DOI: 10.1021/Jm0304515 |
0.358 |
|
| 2002 |
Varty GB, Cohen-Williams ME, Morgan CA, Pylak U, Duffy RA, Lachowicz JE, Carey GJ, Coffin VL. The gerbil elevated plus-maze II: anxiolytic-like effects of selective neurokinin NK1 receptor antagonists. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 27: 371-9. PMID 12225694 DOI: 10.1016/S0893-133X(02)00313-5 |
0.306 |
|
| 2000 |
Varty GB, Paulus MP, Braff DL, Geyer MA. Environmental enrichment and isolation rearing in the rat: effects on locomotor behavior and startle response plasticity. Biological Psychiatry. 47: 864-73. PMID 10807959 DOI: 10.1016/S0006-3223(99)00269-3 |
0.421 |
|
| 2000 |
Paulus MP, Varty GB, Geyer MA. The genetic liability to stress and postweaning isolation have a competitive influence on behavioral organization in rats. Physiology & Behavior. 68: 389-94. PMID 10716550 DOI: 10.1016/S0031-9384(99)00193-6 |
0.405 |
|
| 2000 |
Haile CN, Carey G, Varty GB, Coffin VL. The dopamine D(1) receptor agonist SKF-82958 serves as a discriminative stimulus in the rat. European Journal of Pharmacology. 388: 125-31. PMID 10666503 DOI: 10.1016/S0014-2999(99)00864-X |
0.367 |
|
| 1999 |
Ralph RJ, Varty GB, Kelly MA, Wang YM, Caron MG, Rubinstein M, Grandy DK, Low MJ, Geyer MA. The dopamine D2, but not D3 or D4, receptor subtype is essential for the disruption of prepulse inhibition produced by amphetamine in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 4627-33. PMID 10341260 DOI: 10.1523/Jneurosci.19-11-04627.1999 |
0.715 |
|
| 1999 |
Varty GB, Braff DL, Geyer MA. Is there a critical developmental 'window' for isolation rearing-induced changes in prepulse inhibition of the acoustic startle response? Behavioural Brain Research. 100: 177-83. PMID 10212065 DOI: 10.1016/S0166-4328(98)00129-6 |
0.436 |
|
| 1999 |
Varty GB, Bakshi VP, Geyer MA. M100907, a serotonin 5-HT2A receptor antagonist and putative antipsychotic, blocks dizocilpine-induced prepulse inhibition deficits in Sprague-Dawley and Wistar rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 20: 311-21. PMID 10088132 DOI: 10.1016/S0893-133X(98)00072-4 |
0.695 |
|
| 1999 |
Geyer MA, Krebs-Thomson K, Varty GB. The effects of M100907 in pharmacological and developmental animal models of prepulse inhibition deficits in schizophrenia Neuropsychopharmacology. 21: S134-S142. DOI: 10.1016/S0893-133X(99)00123-2 |
0.451 |
|
| 1998 |
Varty GB, Geyer MA. Effects of isolation rearing on startle reactivity, habituation, and prepulse inhibition in male Lewis, Sprague-Dawley, and Fischer F344 rats. Behavioral Neuroscience. 112: 1450-7. PMID 9926827 DOI: 10.1037//0735-7044.112.6.1450 |
0.42 |
|
| 1998 |
Varty GB, Higgins GA. Dopamine agonist-induced hypothermia and disruption of prepulse inhibition: evidence for a role of D3 receptors? Behavioural Pharmacology. 9: 445-55. PMID 9832930 |
0.4 |
|
| 1998 |
Varty GB, Hauger RL, Geyer MA. Aging effects on the startle response and startle plasticity in Fischer F344 rats. Neurobiology of Aging. 19: 243-51. PMID 9661999 DOI: 10.1016/S0197-4580(98)00053-0 |
0.378 |
|
| 1998 |
Swerdlow NR, Varty GB, Geyer MA. Discrepant findings of clozapine effects on prepulse inhibition of startle: is it the route or the rat? Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 18: 50-6. PMID 9408918 DOI: 10.1016/S0893-133X(97)00110-3 |
0.462 |
|
| 1998 |
Ralph R, Varty G, Kelly M, Grandy D, Low M, Geyer M. 130. Effect of d-amphetamine on prepulse inhibition in dopamine D2 and D4 receptor knockout mice Biological Psychiatry. 43: S39. DOI: 10.1016/S0006-3223(98)90578-9 |
0.702 |
|
| 1998 |
Varty G, Paulus M, Braff D, Geyer M. 46. Social enrichment and isolation rearing in the rat: A behavioral comparison Biological Psychiatry. 43: S14. DOI: 10.1016/S0006-3223(98)90494-2 |
0.361 |
|
| 1997 |
Varty GB, Higgins GA. Investigations into the nature of a 7-OH-DPAT discriminative cue: comparison with D-amphetamine. European Journal of Pharmacology. 339: 101-7. PMID 9473122 DOI: 10.1016/S0014-2999(97)01388-5 |
0.378 |
|
| 1995 |
Varty GB, Higgins GA. Examination of drug-induced and isolation-induced disruptions of prepulse inhibition as models to screen antipsychotic drugs. Psychopharmacology. 122: 15-26. PMID 8711060 DOI: 10.1007/BF02246437 |
0.342 |
|
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