Year |
Citation |
Score |
2024 |
Toivainen S, Xu L, Gobbo F, Della Valle A, Coppola A, Heilig M, Domi E. Different mechanisms underlie compulsive alcohol self-administration in male and female rats. Biology of Sex Differences. 15: 17. PMID 38368341 DOI: 10.1186/s13293-024-00592-5 |
0.329 |
|
2024 |
Petrella M, Borruto AM, Curti L, Domi A, Domi E, Xu L, Barbier E, Ilari A, Heilig M, Weiss F, Mannaioni G, Masi A, Ciccocioppo R. Pharmacological blockage of NOP receptors decreases ventral tegmental area dopamine neuronal activity through GABA receptor-mediated mechanism. Neuropharmacology. 248: 109866. PMID 38364970 DOI: 10.1016/j.neuropharm.2024.109866 |
0.651 |
|
2024 |
Rosas-Vidal LE, Naskar S, Mayo LM, Perini I, Altemus M, Engelbrektsson H, Jagasia P, Heilig M, Patel S. PREFRONTAL CORRELATES OF FEAR GENERALIZATION DURING ENDOCANNABINOID DEPLETION. Biorxiv : the Preprint Server For Biology. PMID 38352388 DOI: 10.1101/2024.01.30.577847 |
0.516 |
|
2023 |
Heilig M. Stress-related neuropeptide systems as targets for treatment of alcohol addiction: A clinical perspective. Journal of Internal Medicine. 293: 559-573. PMID 37052145 DOI: 10.1111/joim.13636 |
0.403 |
|
2023 |
Perini I, Mayo LM, Capusan AJ, Paul ER, Yngve A, Kampe R, Gauffin E, Mazurka R, Ghafouri B, Stensson N, Asratian A, Hamilton JP, Kastbom Å, Gustafsson PA, Heilig M. Resilience to substance use disorder following childhood maltreatment: association with peripheral biomarkers of endocannabinoid function and neural indices of emotion regulation. Molecular Psychiatry. PMID 37041416 DOI: 10.1038/s41380-023-02033-y |
0.524 |
|
2023 |
Domi E, Xu L, Toivainen S, Wiskerke J, Coppola A, Holm L, Augier E, Petrella M, Heilig M. Activation of GABA receptors in central amygdala attenuates activity of PKCδ + neurons and suppresses punishment-resistant alcohol self-administration in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 36739350 DOI: 10.1038/s41386-023-01543-1 |
0.354 |
|
2022 |
Lee MR, Rio D, Kwako L, George DT, Heilig M, Momenan R. Corticotropin-Releasing Factor receptor 1 (CRF1) antagonism in patients with alcohol use disorder and high anxiety levels: effect on neural response during Trier Social Stress Test video feedback. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 36564531 DOI: 10.1038/s41386-022-01521-z |
0.33 |
|
2022 |
MacKillop J, Agabio R, Feldstein Ewing SW, Heilig M, Kelly JF, Leggio L, Lingford-Hughes A, Palmer AA, Parry CD, Ray L, Rehm J. Hazardous drinking and alcohol use disorders. Nature Reviews. Disease Primers. 8: 80. PMID 36550121 DOI: 10.1038/s41572-022-00406-1 |
0.328 |
|
2021 |
Perini I, Kroll S, Mayo LM, Heilig M. Social Acts and Anticipation of Social Feedback. Current Topics in Behavioral Neurosciences. PMID 34784025 DOI: 10.1007/7854_2021_274 |
0.484 |
|
2021 |
Mayo LM, Rabinak CA, Hill MN, Heilig M. Targeting the Endocannabinoid System in the Treatment of Posttraumatic Stress Disorder: A Promising Case of Preclinical-Clinical Translation? Biological Psychiatry. PMID 34598785 DOI: 10.1016/j.biopsych.2021.07.019 |
0.542 |
|
2021 |
Kroll SL, Mayo LM, Asratian A, Yngve A, Perini I, Heilig M. Negative self-evaluation induced by acute stress indexed using facial EMG. Psychoneuroendocrinology. 133: 105402. PMID 34530295 DOI: 10.1016/j.psyneuen.2021.105402 |
0.531 |
|
2021 |
Domi E, Xu L, Toivainen S, Nordeman A, Gobbo F, Venniro M, Shaham Y, Messing RO, Visser E, van den Oever MC, Holm L, Barbier E, Augier E, Heilig M. A neural substrate of compulsive alcohol use. Science Advances. 7. PMID 34407947 DOI: 10.1126/sciadv.abg9045 |
0.379 |
|
2021 |
Capusan AJ, Gustafsson PA, Kuja-Halkola R, Igelström K, Mayo LM, Heilig M. Correction: Re-examining the link between childhood maltreatment and substance use disorder: a prospective, genetically informative study. Molecular Psychiatry. PMID 33931734 DOI: 10.1038/s41380-021-01115-z |
0.488 |
|
2021 |
Perini I, Gustafsson PA, Igelström K, Jasiunaite-Jokubaviciene B, Kämpe R, Mayo LM, Molander J, Olausson H, Zetterqvist M, Heilig M. Altered relationship between subjective perception and central representation of touch hedonics in adolescents with autism-spectrum disorder. Translational Psychiatry. 11: 224. PMID 33866324 DOI: 10.1038/s41398-021-01341-7 |
0.499 |
|
2021 |
Capusan AJ, Gustafsson PA, Kuja-Halkola R, Igelström K, Mayo L, Heilig M. Re-examining the link between childhood maltreatment and substance use disorder: a prospective, genetically informative study. Molecular Psychiatry. PMID 33824431 DOI: 10.1038/s41380-021-01071-8 |
0.487 |
|
2021 |
Domi E, Domi A, Adermark L, Heilig M, Augier E. Neurobiology of alcohol seeking behavior. Journal of Neurochemistry. PMID 33704789 DOI: 10.1111/jnc.15343 |
0.388 |
|
2021 |
Barchiesi R, Chanthongdee K, Domi E, Gobbo F, Coppola A, Asratian A, Toivainen S, Holm L, Augier G, Xu L, Augier E, Heilig M, Barbier E. Stress-induced escalation of alcohol self-administration, anxiety-like behavior, and elevated amygdala Avp expression in a susceptible subpopulation of rats. Addiction Biology. e13009. PMID 33565224 DOI: 10.1111/adb.13009 |
0.373 |
|
2021 |
Peng SY, Shi Z, Zhou DS, Wang XY, Li XX, Liu XL, Wang WD, Lin GN, Pan BX, Voon V, Grace AA, Heilig M, Wong ML, Yuan TF. Reduced motor cortex GABAR function following chronic alcohol exposure. Molecular Psychiatry. PMID 33432190 DOI: 10.1038/s41380-020-01009-6 |
0.32 |
|
2020 |
Mayo LM, Perini I, Gustafsson PA, Hamilton JP, Kämpe R, Heilig M, Zetterqvist M. Psychophysiological and Neural Support for Enhanced Emotional Reactivity in Female Adolescents With Nonsuicidal Self-injury. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. PMID 33541848 DOI: 10.1016/j.bpsc.2020.11.004 |
0.481 |
|
2020 |
Barbier E, Barchiesi R, Domi A, Chanthongdee K, Domi E, Augier G, Augier E, Xu L, Adermark L, Heilig M. Downregulation of Synaptotagmin 1 in the Prelimbic Cortex Drives Alcohol-Associated Behaviors in Rats. Biological Psychiatry. PMID 33160605 DOI: 10.1016/j.biopsych.2020.08.027 |
0.368 |
|
2020 |
Domi E, Xu L, Pätz M, Nordeman A, Augier G, Holm L, Toivainen S, Augier E, Hansson AC, Heilig M. Nicotine increases alcohol self-administration in male rats via a mu-opioid mechanism within the mesolimbic pathway. British Journal of Pharmacology. PMID 32697329 DOI: 10.1111/Bph.15210 |
0.454 |
|
2020 |
Schwandt ML, Diazgranados N, Umhau JC, Kwako LE, George DT, Heilig M. PPARγ activation by pioglitazone does not suppress cravings for alcohol, and is associated with a risk of myopathy in treatment seeking alcohol dependent patients: a randomized controlled proof of principle study. Psychopharmacology. PMID 32445052 DOI: 10.1007/S00213-020-05540-W |
0.467 |
|
2020 |
Ray LA, Grodin EN, Leggio L, Bechtholt AJ, Becker H, Feldstein Ewing SW, Jentsch JD, King AC, Mason BJ, O'Malley S, MacKillop J, Heilig M, Koob GF. The future of translational research on alcohol use disorder. Addiction Biology. e12903. PMID 32286721 DOI: 10.1111/Adb.12903 |
0.56 |
|
2020 |
Best LM, Williams B, Le Foll B, Mansouri E, Bazinet RP, Lin L, De Luca V, Lagzdins D, Rusjan P, Tyndale RF, Wilson AA, Hendershot CS, Heilig M, Houle S, Tong J, et al. Lower brain fatty acid amide hydrolase in treatment-seeking patients with alcohol use disorder: a positron emission tomography study with [C-11]CURB. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31910433 DOI: 10.1038/S41386-020-0606-2 |
0.428 |
|
2020 |
Blokhin I, Van Booven D, Mayfield D, Argemi J, Bataller R, Barbier E, Heilig M, Wahlestedt C. Genome-Wide Effects of Alcohol Use Disorder on Long Non-Coding RNAs and Splicing in Brain and Liver Biological Psychiatry. 87: S178-S179. DOI: 10.1016/J.Biopsych.2020.02.469 |
0.338 |
|
2019 |
Perini I, Kämpe R, Arlestig T, Karlsson H, Löfberg A, Pietrzak M, Zangen A, Heilig M. Repetitive transcranial magnetic stimulation targeting the insular cortex for reduction of heavy drinking in treatment-seeking alcohol-dependent subjects: a randomized controlled trial. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31711065 DOI: 10.1038/S41386-019-0565-7 |
0.428 |
|
2019 |
Muench C, Charlet K, Balderston NL, Grillon C, Heilig M, Cortes CR, Momenan R, Lohoff FW. Fear conditioning and extinction in alcohol dependence: Evidence for abnormal amygdala reactivity. Addiction Biology. e12835. PMID 31702089 DOI: 10.1111/Adb.12835 |
0.346 |
|
2019 |
Ljungvall H, Persson A, Åsenlöf P, Heilig M, Ekselius L. Reliability of the Addiction Severity Index self-report form (ASI-SR): a self-administered questionnaire based on the Addiction Severity Index composite score domains. Nordic Journal of Psychiatry. 1-7. PMID 31696752 DOI: 10.1080/08039488.2019.1666300 |
0.301 |
|
2019 |
Domi E, Caputi FF, Romualdi P, Domi A, Scuppa G, Candeletti S, Atkins A, Heilig M, Demopulos G, Gaitanaris G, Ciccocioppo R, Ubaldi M. Activation of PPARγ attenuates the expression of physical and affective nicotine withdrawal symptoms through mechanisms involving amygdala and hippocampus neurotransmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31685649 DOI: 10.1523/Jneurosci.1922-19.2019 |
0.55 |
|
2019 |
Heilig M, Augier E, Pfarr S, Sommer WH. Developing neuroscience-based treatments for alcohol addiction: A matter of choice? Translational Psychiatry. 9: 255. PMID 31594920 DOI: 10.1038/S41398-019-0591-6 |
0.461 |
|
2019 |
Mayo LM, Asratian A, Lindé J, Morena M, Haataja R, Hammar V, Augier G, Hill MN, Heilig M. Elevated Anandamide, Enhanced Recall of Fear Extinction, and Attenuated Stress Responses Following Inhibition of Fatty Acid Amide Hydrolase: A Randomized, Controlled Experimental Medicine Trial. Biological Psychiatry. PMID 31590924 DOI: 10.1016/J.Biopsych.2019.07.034 |
0.567 |
|
2019 |
Perini I, Gustafsson PA, Hamilton JP, Kämpe R, Mayo LM, Heilig M, Zetterqvist M. Brain-based Classification of Negative Social Bias in Adolescents With Nonsuicidal Self-injury: Findings From Simulated Online Social Interaction. Eclinicalmedicine. 13: 81-90. PMID 31517265 DOI: 10.1016/J.Eclinm.2019.06.016 |
0.548 |
|
2019 |
Carvalho AF, Heilig M, Perez A, Probst C, Rehm J. Alcohol use disorders. Lancet (London, England). 394: 781-792. PMID 31478502 DOI: 10.1016/S0140-6736(19)31775-1 |
0.424 |
|
2019 |
Rehm J, Heilig M, Gual A. ICD-11 for Alcohol Use Disorders: Not a Convincing Answer to the Challenges. Alcoholism, Clinical and Experimental Research. PMID 31424579 DOI: 10.1111/Acer.14182 |
0.416 |
|
2019 |
Johnstone AL, Andrade NS, Barbier E, Khomtchouk BB, Rienas CA, Lowe K, Van Booven DJ, Domi E, Esanov R, Vilca S, Tapocik JD, Rodriguez K, Maryanski D, Keogh MC, Meinhardt MW, ... ... Heilig M, et al. Dysregulation of the histone demethylase KDM6B in alcohol dependence is associated with epigenetic regulation of inflammatory signaling pathways. Addiction Biology. e12816. PMID 31373129 DOI: 10.1111/Adb.12816 |
0.447 |
|
2019 |
Nelson BS, Fulenwider HD, Nennig SE, Smith BM, Sequeira MK, Chimberoff SH, Richie CT, Cheng K, Rice KC, Harvey BK, Heilig M, Schank JR. Escalated Alcohol Self-Administration and Sensitivity to Yohimbine-Induced Reinstatement in Alcohol Preferring Rats: Potential Role of Neurokinin-1 Receptors in the Amygdala. Neuroscience. PMID 31242442 DOI: 10.1016/J.Neuroscience.2019.06.023 |
0.496 |
|
2019 |
Mayo LM, Heilig M. In the face of stress: Interpreting individual differences in stress-induced facial expressions. Neurobiology of Stress. 10: 100166. PMID 31193535 DOI: 10.1016/J.Ynstr.2019.100166 |
0.561 |
|
2019 |
Ree A, Morrison I, Olausson H, Sailer U, Heilig M, Mayo LM. Using Facial Electromyography to Assess Facial Muscle Reactions to Experienced and Observed Affective Touch in Humans. Journal of Visualized Experiments : Jove. PMID 30933066 DOI: 10.3791/59228 |
0.544 |
|
2019 |
Mayo L, Linde J, Asratian A, Morena M, Hill M, Heilig M. S31. Beneficial Effects of FAAH Inhibition on Fear- and Stress-Related Behaviors in Healthy Humans Biological Psychiatry. 85: S308. DOI: 10.1016/J.Biopsych.2019.03.782 |
0.566 |
|
2019 |
Perini I, Gustafsson P, Hamilton P, Kämpe R, Mayo L, Zetterqvist M, Heilig M. T57. Social Interaction Processing in Adolescents With Non-Suicidal Self-Injury (NSSI) Behavior Biological Psychiatry. 85: S150-S151. DOI: 10.1016/J.Biopsych.2019.03.380 |
0.527 |
|
2019 |
Harel M, Barnea-Ygael N, Shalev H, Besser I, Salti M, Kampe R, Heilig M, Zangen A. O7. Deep Transcranial Magnetic Stimulation Over the Medial Prefrontal and Anterior Cingulate Cortices Alters Brain Connectivity and Reduces Relapse to Alcohol Use Biological Psychiatry. 85: S108. DOI: 10.1016/J.Biopsych.2019.03.272 |
0.352 |
|
2018 |
Mayo LM, Heilig M. A Hippocampal Signature of Posttraumatic Stress Disorder Vulnerability. Biological Psychiatry. 84: 78-79. PMID 31178061 DOI: 10.1016/J.Biopsych.2018.04.015 |
0.548 |
|
2018 |
Grodin EN, Sussman L, Sundby K, Brennan GM, Diazgranados N, Heilig M, Momenan R. Neural Correlates of Compulsive Alcohol Seeking in Heavy Drinkers. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. PMID 30143454 DOI: 10.1016/J.Bpsc.2018.06.009 |
0.471 |
|
2018 |
Mayo LM, Asratian A, Lindé J, Holm L, Nätt D, Augier G, Stensson N, Vecchiarelli HA, Balsevich G, Aukema RJ, Ghafouri B, Spagnolo PA, Lee FS, Hill MN, Heilig M. Protective effects of elevated anandamide on stress and fear-related behaviors: translational evidence from humans and mice. Molecular Psychiatry. PMID 30120421 DOI: 10.1038/S41380-018-0215-1 |
0.59 |
|
2018 |
Mayo LM, Lindé J, Olausson H, Heilig M, Morrison I. Putting a good face on touch: Facial expression reflects the affective valence of caress-like touch across modalities. Biological Psychology. PMID 30003943 DOI: 10.1016/J.Biopsycho.2018.07.001 |
0.542 |
|
2018 |
Augier E, Barbier E, Dulman RS, Licheri V, Augier G, Domi E, Barchiesi R, Farris S, Nätt D, Mayfield RD, Adermark L, Heilig M. A molecular mechanism for choosing alcohol over an alternative reward. Science (New York, N.Y.). 360: 1321-1326. PMID 29930131 DOI: 10.1126/Science.Aao1157 |
0.488 |
|
2018 |
Sequeira MK, Nelson BS, Fulenwider HD, King CE, Nennig SE, Bohannon JB, Cheng K, Rice KC, Heilig M, Schank JR. The neurokinin-1 receptor mediates escalated alcohol intake induced by multiple drinking models. Neuropharmacology. 137: 194-201. PMID 29758386 DOI: 10.1016/J.Neuropharm.2018.05.005 |
0.508 |
|
2018 |
Lee MR, Tapocik JD, Ghareeb M, Schwandt ML, Dias AA, Le AN, Cobbina E, Farinelli LA, Bouhlal S, Farokhnia M, Heilig M, Akhlaghi F, Leggio L. The novel ghrelin receptor inverse agonist PF-5190457 administered with alcohol: preclinical safety experiments and a phase 1b human laboratory study. Molecular Psychiatry. PMID 29728704 DOI: 10.1038/S41380-018-0064-Y |
0.481 |
|
2018 |
Lee JS, Sorcher JL, Rosen AD, Damadzic R, Sun H, Schwandt M, Heilig M, Kelly J, Mauro KL, Luo A, Rosoff D, Muench C, Jung J, Kaminsky ZA, Lohoff FW. Genetic Association and Expression Analyses of the Phosphatidylinositol-4-Phosphate 5-Kinase (PIP5K1C) Gene in Alcohol Use Disorder - Relevance for Pain Signaling and Alcohol Use. Alcoholism, Clinical and Experimental Research. PMID 29667742 DOI: 10.1111/Acer.13751 |
0.37 |
|
2018 |
Domi E, Barbier E, Augier E, Augier G, Gehlert D, Barchiesi R, Thorsell A, Holm L, Heilig M. Preclinical evaluation of the kappa-opioid receptor antagonist CERC-501 as a candidate therapeutic for alcohol use disorders. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 43: 1805-1812. PMID 29463912 DOI: 10.1038/S41386-018-0015-Y |
0.505 |
|
2018 |
Stojakovic A, Walczak M, Cieślak PE, Trenk A, Sköld J, Zajdel J, Mirrasekhian E, Karlsson C, Thorsell A, Heilig M, Parkitna JR, Błasiak T, Engblom D. Several behavioral traits relevant for alcoholism are controlled by ɣ2 subunit containing GABAreceptors on dopamine neurons in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29463910 DOI: 10.1038/S41386-018-0022-Z |
0.463 |
|
2018 |
Van Hedger K, Keedy SK, Mayo LM, Heilig M, de Wit H. Neural responses to cues paired with methamphetamine in healthy volunteers. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29463908 DOI: 10.1038/S41386-017-0005-5 |
0.631 |
|
2018 |
Zallar LJ, Tunstall BJ, Richie CT, Zhang YJ, You ZB, Gardner EL, Heilig M, Pickel J, Koob GF, Vendruscolo LF, Harvey BK, Leggio L. Development and initial characterization of a novel ghrelin receptor CRISPR/Cas9 knockout wistar rat model. International Journal of Obesity (2005). PMID 29453460 DOI: 10.1038/S41366-018-0013-5 |
0.58 |
|
2018 |
Cortes CR, Grodin EN, Mann CL, Mathur K, Kerich M, Zhu X, Schwandt M, Diazgranados N, George DT, Momenan R, Heilig M. Insula Sensitivity to Unfairness in Alcohol Use Disorder. Alcohol and Alcoholism (Oxford, Oxfordshire). PMID 29309499 DOI: 10.1093/Alcalc/Agx115 |
0.402 |
|
2018 |
Heilig M, Wahlestedt C, Barbier E, Johnstone A. 10. Epigenetic Enzymes as Novel Therapeutic Targets in Alcohol Addiction Biological Psychiatry. 83: S4. DOI: 10.1016/J.Biopsych.2018.02.027 |
0.396 |
|
2017 |
Malik S, Jacobs M, Cho SS, Boileau I, Blumberger D, Heilig M, Wilson A, Daskalakis ZJ, Strafella AP, Zangen A, Le Foll B. Deep TMS of the insula using the H-coil modulates dopamine release: a crossover [(11)C] PHNO-PET pilot trial in healthy humans. Brain Imaging and Behavior. PMID 29170944 DOI: 10.1007/S11682-017-9800-1 |
0.322 |
|
2017 |
Lindell SG, Schwandt ML, Suomi SJ, Rice KC, Heilig M, Barr CS. Intermittent Access to Ethanol Induces Escalated Alcohol Consumption in Primates. Journal of Addictive Behaviors, Therapy & Rehabilitation. 6. PMID 29082267 DOI: 10.4172/2324-9005.1000163 |
0.371 |
|
2017 |
Baker M, Lindell SG, Driscoll CA, Zhou Z, Yuan Q, Schwandt ML, Miller-Crews I, Simpson EA, Paukner A, Ferrari PF, Sindhu RK, Razaqyar M, Sommer WH, Lopez JF, Thompson RC, ... ... Heilig M, et al. Early rearing history influences oxytocin receptor epigenetic regulation in rhesus macaques. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078292 DOI: 10.1073/Pnas.1706206114 |
0.338 |
|
2017 |
Schank JR, Heilig M. Substance P and the Neurokinin-1 Receptor: The New CRF. International Review of Neurobiology. 136: 151-175. PMID 29056150 DOI: 10.1016/Bs.Irn.2017.06.008 |
0.399 |
|
2017 |
Barbier E, Heilig M. mTORC and ProSAPiP1: How Alcohol Changes Synapses of Reward Circuitry. Neuron. 96: 6-8. PMID 28957677 DOI: 10.1016/J.Neuron.2017.09.016 |
0.429 |
|
2017 |
Nennig SE, Fulenwider HD, Chimberoff SH, Smith BM, Eskew JE, Sequeira MK, Karlsson C, Liang C, Chen J, Heilig M, Schank JR. Selective Lesioning of Nuclear Factor kB Activated Cells in the Nucleus Accumbens Shell Attenuates Alcohol Place Preference. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28901327 DOI: 10.1038/Npp.2017.214 |
0.462 |
|
2017 |
Aoun EG, Jimenez VA, Vendruscolo LF, Walter NAR, Barbier E, Ferrulli A, Haass-Koffler CL, Darakjian P, Lee MR, Addolorato G, Heilig M, Hitzemann R, Koob GF, Grant KA, Leggio L. A relationship between the aldosterone-mineralocorticoid receptor pathway and alcohol drinking: preliminary translational findings across rats, monkeys and humans. Molecular Psychiatry. PMID 28461696 DOI: 10.1038/Mp.2017.97 |
0.66 |
|
2017 |
Augier E, Dulman RS, Damadzic R, Pilling A, Hamilton JP, Heilig M. The GABAB Positive Allosteric Modulator, ADX71441 Attenuates Alcohol Self-Administration and Relapse to Alcohol Seeking in Rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28294133 DOI: 10.1038/Npp.2017.53 |
0.535 |
|
2017 |
Badiani A, Berridge KC, Heilig M, Nutt DJ, Robinson TE. Addiction research and theory: a commentary on the Surgeon General's Report on alcohol, drugs, and health. Addiction Biology. PMID 28224686 DOI: 10.1111/Adb.12497 |
0.357 |
|
2017 |
Augier E, Dulman RS, Singley E, Heilig M. A Method for Evaluating the Reinforcing Properties of Ethanol in Rats without Water Deprivation, Saccharin Fading or Extended Access Training. Journal of Visualized Experiments : Jove. PMID 28190044 DOI: 10.3791/53305 |
0.388 |
|
2017 |
Persson A, Back SE, Killeen TK, Brady KT, Schwandt ML, Heilig M, Magnusson Å. Concurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure (COPE): A Pilot Study in Alcohol-dependent Women. Journal of Addiction Medicine. PMID 28079572 DOI: 10.1097/Adm.0000000000000286 |
0.322 |
|
2017 |
Gehlert DR, Rorick-Kehn L, Thorsell A, Paterson B, Heilig M. Evaluation of CERC-501, a selective kappa opioid antagonist in preclinical models of alcoholism Drug and Alcohol Dependence. 171: e70. DOI: 10.1016/J.Drugalcdep.2016.08.202 |
0.405 |
|
2017 |
Grodin E, Sussman L, Sundby K, Brennan G, Heilig M, Momenan R. 196. The Neural Correlates of Compulsive Alcohol Seeking Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.209 |
0.426 |
|
2017 |
Aziz AMA, Brothers S, Sartor G, Heilig M, Wahlestedt C, Thorsell A. The Nociceptin/Orphanin FQ receptor agonist SR-8993 as a candidate therapeutic for alcohol use disorders: Validation in rat models Alcohol. 60: 233. DOI: 10.1016/J.ALCOHOL.2017.02.313 |
0.348 |
|
2017 |
Domi E, Gehlert D, Barbier E, Augier E, Augier G, Malm H, Aziz A, Thorsell A, Heilig M. The novel kappa opioid receptor antagonist CERC-501 attenuates alcohol seeking and withdrawal anxiety Alcohol. 60: 230. DOI: 10.1016/J.Alcohol.2017.02.299 |
0.446 |
|
2017 |
Schwandt ML, Heilig M, George DT, Hommer D, Ramchandani VA. Childhood trauma in alcohol dependence: Vulnerability and relative resilience Alcohol. 60: 213. DOI: 10.1016/J.Alcohol.2017.02.226 |
0.431 |
|
2017 |
Barbier E, Johnstone A, Khomtchouk B, Tapocik J, Pitcairn C, Rehman F, Augier E, Borich A, Schank J, Rienas C, Van Booven D, Sun H, Nätt D, Wahlestedt C, Heilig M. Epigenetic enzymes as a novel class of targets for disease-modifying pharmacotherapies in alcohol addiction Alcohol. 60: 209. DOI: 10.1016/J.Alcohol.2017.02.211 |
0.373 |
|
2016 |
Domi E, Uhrig S, Soverchia L, Spanagel R, Hansson AC, Barbier E, Heilig M, Ciccocioppo R, Ubaldi M. Genetic deletion of neuronal PPARγ enhances the emotional response to acute stress and exacerbates anxiety: An effect reversed by rescue of amygdala PPARγ function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 27810934 DOI: 10.1523/Jneurosci.4127-15.2016 |
0.532 |
|
2016 |
Spagnolo PA, Ramchandani VA, Schwandt ML, Kwako LE, George DT, Mayo LM, Hillard CJ, Heilig M. FAAH Gene Variation Moderates Stress Response and Symptom Severity in Patients with Posttraumatic Stress Disorder and Comorbid Alcohol Dependence. Alcoholism, Clinical and Experimental Research. PMID 27716956 DOI: 10.1111/Acer.13210 |
0.618 |
|
2016 |
Heilig M, Barbier E, Johnstone AL, Tapocik J, Meinhardt MW, Pfarr S, Wahlestedt CR, Sommer WH. Reprogramming of mPFC transcriptome and function in alcohol dependence. Genes, Brain, and Behavior. PMID 27657733 DOI: 10.1111/Gbb.12344 |
0.461 |
|
2016 |
Karlsson C, Rehman F, Damadzic R, Atkins AL, Schank JR, Gehlert DR, Steensland P, Thorsell A, Heilig M. Erratum to: The melanin-concentrating hormone-1 receptor modulates alcohol-induced reward and DARPP-32 phosphorylation. Psychopharmacology. PMID 27650828 DOI: 10.1007/S00213-016-4434-3 |
0.458 |
|
2016 |
Epstein DH, Kennedy AP, Furnari M, Heilig M, Shaham Y, Phillips KA, Preston KL. Effect of the CRF1-receptor antagonist pexacerfont on stress-induced eating and food craving. Psychopharmacology. PMID 27595147 DOI: 10.1007/S00213-016-4424-5 |
0.337 |
|
2016 |
Karlsson C, Aziz AM, Rehman F, Pitcairn C, Barchiesi R, Barbier E, Wendel Hansen M, Gehlert D, Steensland P, Heilig M, Thorsell A. Melanin-Concentrating Hormone and Its MCH-1 Receptor: Relationship Between Effects on Alcohol and Caloric Intake. Alcoholism, Clinical and Experimental Research. PMID 27579857 DOI: 10.1111/Acer.13181 |
0.436 |
|
2016 |
Barbier E, Johnstone AL, Khomtchouk BB, Tapocik JD, Pitcairn C, Rehman F, Augier E, Borich A, Schank JR, Rienas CA, Van Booven DJ, Sun H, Nätt D, Wahlestedt C, Heilig M. Dependence-induced increase of alcohol self-administration and compulsive drinking mediated by the histone methyltransferase PRDM2. Molecular Psychiatry. PMID 27573876 DOI: 10.1038/Mp.2016.131 |
0.488 |
|
2016 |
Aziz AM, Brothers S, Sartor G, Holm L, Heilig M, Wahlestedt C, Thorsell A. The nociceptin/orphanin FQ receptor agonist SR-8993 as a candidate therapeutic for alcohol use disorders: validation in rat models. Psychopharmacology. PMID 27515665 DOI: 10.1016/J.Alcohol.2017.02.313 |
0.514 |
|
2016 |
Driscoll CA, Lindell SG, Schwandt ML, Suomi SJ, Higley JD, Heilig M, Barr CS. OPRM1 genotype interacts with serotonin system dysfunction to predict alcohol-heightened aggression in primates. Addiction Biology. PMID 27484010 DOI: 10.1111/Adb.12428 |
0.45 |
|
2016 |
Augier E, Dulman RS, Rauffenbart C, Augier G, Cross AJ, Heilig M. The mGluR2 Positive Allosteric Modulator, AZD8529 and Cue-Induced Relapse to Alcohol Seeking in Rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27339394 DOI: 10.1038/Npp.2016.107 |
0.814 |
|
2016 |
Karlsson C, Schank JR, Rehman F, Stojakovic A, Björk K, Barbier E, Solomon M, Tapocik J, Engblom D, Thorsell A, Heilig M. Proinflammatory signaling regulates voluntary alcohol intake and stress-induced consumption after exposure to social defeat stress in mice. Addiction Biology. PMID 27273552 DOI: 10.1111/Adb.12416 |
0.442 |
|
2016 |
Heilig M, Sommer WH, Spanagel R. The Need for Treatment Responsive Translational Biomarkers in Alcoholism Research. Current Topics in Behavioral Neurosciences. PMID 27240677 DOI: 10.1007/7854_2015_5006 |
0.438 |
|
2016 |
Sells JR, Waters AJ, Schwandt ML, Kwako LE, Heilig M, George DT, Ramchandani VA. Characterization of comorbid PTSD in treatment-seeking alcohol dependent inpatients: Severity and personality trait differences. Drug and Alcohol Dependence. PMID 27114205 DOI: 10.1016/J.Drugalcdep.2016.03.016 |
0.4 |
|
2016 |
Schwandt ML, Cortes CR, Kwako LE, George DT, Momenan R, Sinha R, Grigoriadis DE, Leggio L, Heilig M. The CRF1 Antagonist Verucerfont in Anxious Alcohol Dependent Women: Translation of Neuroendocrine, but not of Anti-Craving Effects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27109623 DOI: 10.1038/Npp.2016.61 |
0.51 |
|
2016 |
Gowin JL, Vatsalya V, Westman JG, Schwandt ML, Bartlett S, Heilig M, Momenan R, Ramchandani VA. The Effect of Varenicline on the Neural Processing of Fearful Faces and the Subjective Effects of Alcohol in Heavy Drinkers. Alcoholism, Clinical and Experimental Research. PMID 27062270 DOI: 10.1111/Acer.13046 |
0.442 |
|
2016 |
Karlsson C, Rehman F, Damdazic R, Atkins AL, Schank JR, Gehlert DR, Steensland P, Thorsell A, Heilig M. The melanin-concentrating hormone-1 receptor modulates alcohol-induced reward and DARPP-32 phosphorylation. Psychopharmacology. PMID 27044354 DOI: 10.1007/s00213-016-4285-y |
0.351 |
|
2016 |
Caruso V, Sreedharan S, Carlini VP, Jacobsson JA, Haitina T, Hammer J, Stephansson O, Crona F, Sommer WH, Risérus U, Lannfelt L, Marcus C, Heilig M, de Barioglio SR, Fredriksson R, et al. mRNA GPR162 changes are associated with decreased food intake in rat, and its human genetic variants with impairments in glucose homeostasis in two Swedish cohorts. Gene. PMID 26827797 DOI: 10.1016/J.Gene.2016.01.044 |
0.318 |
|
2016 |
Heilig M, Leggio L. What the alcohol doctor ordered from the neuroscientist: Theragnostic biomarkers for personalized treatments. Progress in Brain Research. 224: 401-18. PMID 26822368 DOI: 10.1016/Bs.Pbr.2015.07.023 |
0.432 |
|
2015 |
Herman MA, Varodayan FP, Oleata CS, Luu G, Kirson D, Heilig M, Ciccocioppo R, Roberto M. Glutamatergic transmission in the central nucleus of the amygdala is selectively altered in Marchigian Sardinian alcohol-preferring rats: Alcohol and CRF effects. Neuropharmacology. 102: 21-31. PMID 26519902 DOI: 10.1016/J.Neuropharm.2015.10.027 |
0.576 |
|
2015 |
Ayanwuyi LO, Stopponi S, Ubaldi M, Cippitelli A, Nasuti C, Damadzic R, Heilig M, Schank J, Cheng K, Rice KC, Ciccocioppo R. Neurokinin 1 receptor blockade in the medial amygdala attenuates alcohol drinking in rats with innate anxiety but not in wistar rats. British Journal of Pharmacology. PMID 26275374 DOI: 10.1111/Bph.13280 |
0.611 |
|
2015 |
Vatsalya V, Gowin JL, Schwandt ML, Momenan R, Coe MA, Cooke ME, Hommer DW, Bartlett S, Heilig M, Ramchandani VA. Effects of Varenicline on Neural Correlates of Alcohol Salience in Heavy Drinkers. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). PMID 26209857 DOI: 10.1093/Ijnp/Pyv068 |
0.456 |
|
2015 |
Schank JR, Nelson BS, Damadzic R, Tapocik JD, Yao M, King CE, Rowe KE, Cheng K, Rice KC, Heilig M. Neurokinin-1 receptor antagonism attenuates neuronal activity triggered by stress-induced reinstatement of alcohol seeking. Neuropharmacology. 99: 106-114. PMID 26188146 DOI: 10.1016/J.Neuropharm.2015.07.009 |
0.37 |
|
2015 |
Suchankova P, Yan J, Schwandt ML, Stangl BL, Caparelli EC, Momenan R, Jerlhag E, Engel JA, Hodgkinson CA, Egli M, Lopez MF, Becker HC, Goldman D, Heilig M, Ramchandani VA, et al. The glucagon-like peptide-1 receptor as a potential treatment target in alcohol use disorder: evidence from human genetic association studies and a mouse model of alcohol dependence. Translational Psychiatry. 5: e583. PMID 26080318 DOI: 10.1038/Tp.2015.68 |
0.484 |
|
2015 |
Robinson JE, Vardy E, DiBerto JF, Chefer VI, White KL, Fish EW, Chen M, Gigante E, Krouse MC, Sun H, Thorsell A, Roth BL, Heilig M, Malanga CJ. Receptor Reserve Moderates Mesolimbic Responses to Opioids in a Humanized Mouse Model of the OPRM1 A118G Polymorphism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 2614-22. PMID 25881115 DOI: 10.1038/Npp.2015.109 |
0.654 |
|
2015 |
Barbier E, Tapocik JD, Juergens N, Pitcairn C, Borich A, Schank JR, Sun H, Schuebel K, Zhou Z, Yuan Q, Vendruscolo LF, Goldman D, Heilig M. DNA methylation in the medial prefrontal cortex regulates alcohol-induced behavior and plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 6153-64. PMID 25878287 DOI: 10.1523/Jneurosci.4571-14.2015 |
0.447 |
|
2015 |
Spagnolo PA, Colloca L, Heilig M. The role of expectation in the therapeutic outcomes of alcohol and drug addiction treatments. Alcohol and Alcoholism (Oxford, Oxfordshire). 50: 282-5. PMID 25761920 DOI: 10.1093/Alcalc/Agv015 |
0.385 |
|
2015 |
de Guglielmo G, Melis M, De Luca MA, Kallupi M, Li HW, Niswender K, Giordano A, Senzacqua M, Somaini L, Cippitelli A, Gaitanaris G, Demopulos G, Damadzic R, Tapocik J, Heilig M, et al. PPARc activation attenuates opioid consumption and modulates mesolimbic dopamine transmission. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1052. PMID 25668637 DOI: 10.1038/Npp.2014.305 |
0.543 |
|
2015 |
Bilbao A, Robinson JE, Heilig M, Malanga CJ, Spanagel R, Sommer WH, Thorsell A. A pharmacogenetic determinant of mu-opioid receptor antagonist effects on alcohol reward and consumption: evidence from humanized mice. Biological Psychiatry. 77: 850-8. PMID 25442002 DOI: 10.1016/J.Biopsych.2014.08.021 |
0.689 |
|
2015 |
Kwako LE, Spagnolo PA, Schwandt ML, Thorsell A, George DT, Momenan R, Rio DE, Huestis M, Anizan S, Concheiro M, Sinha R, Heilig M. The corticotropin releasing hormone-1 (CRH1) receptor antagonist pexacerfont in alcohol dependence: a randomized controlled experimental medicine study. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1053-63. PMID 25409596 DOI: 10.1038/Npp.2014.306 |
0.506 |
|
2015 |
Schmeichel BE, Barbier E, Misra KK, Contet C, Schlosburg JE, Grigoriadis D, Williams JP, Karlsson C, Pitcairn C, Heilig M, Koob GF, Vendruscolo LF. Hypocretin receptor 2 antagonism dose-dependently reduces escalated heroin self-administration in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1123-9. PMID 25367502 DOI: 10.1038/Npp.2014.293 |
0.785 |
|
2015 |
Senatorov VV, Damadzic R, Mann CL, Schwandt ML, George DT, Hommer DW, Heilig M, Momenan R. Reduced anterior insula, enlarged amygdala in alcoholism and associated depleted von Economo neurons. Brain : a Journal of Neurology. 138: 69-79. PMID 25367022 DOI: 10.1093/Brain/Awu305 |
0.445 |
|
2015 |
de Guglielmo G, Melis M, De Luca MA, Kallupi M, Li HW, Niswender K, Giordano A, Senzacqua M, Somaini L, Cippitelli A, Gaitanaris G, Demopulos G, Damadzic R, Tapocik J, Heilig M, et al. PPARγ activation attenuates opioid consumption and modulates mesolimbic dopamine transmission. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 927-37. PMID 25311134 DOI: 10.1038/npp.2014.268 |
0.485 |
|
2015 |
Cippitelli A, Ayanwuyi LO, Barbier E, Domi E, Lerma-Cabrera JM, Carvajal F, Scuppa G, Li H, Ubaldi M, Heilig M, Roberto M, Ciccocioppo R. Polymorphism in the corticotropin-releasing factor receptor 1 (CRF1-R) gene plays a role in shaping the high anxious phenotype of Marchigian Sardinian alcohol-preferring (msP) rats. Psychopharmacology. 232: 1083-93. PMID 25260340 DOI: 10.1007/S00213-014-3743-7 |
0.621 |
|
2015 |
Kwako LE, George DT, Schwandt ML, Spagnolo PA, Momenan R, Hommer DW, Diamond CA, Sinha R, Shaham Y, Heilig M. The neurokinin-1 receptor antagonist aprepitant in co-morbid alcohol dependence and posttraumatic stress disorder: a human experimental study. Psychopharmacology. 232: 295-304. PMID 25030801 DOI: 10.1007/S00213-014-3665-4 |
0.467 |
|
2015 |
Kwako LE, Schwandt ML, Sells JR, Ramchandani VA, Hommer DW, George DT, Sinha R, Heilig M. Methods for inducing alcohol craving in individuals with co-morbid alcohol dependence and posttraumatic stress disorder: behavioral and physiological outcomes. Addiction Biology. 20: 733-46. PMID 24806358 DOI: 10.1111/Adb.12150 |
0.472 |
|
2015 |
Suchankova P, Yan, J, Schwandt ML, Stangl BL, Caparelli EC, Momenan R, Hodgkinson CA, Goldman D, Heilig M, Ramchandani VA, Nilsson S, von der Pahlen B, Santtila P, Sandnabba K, et al. SY15-3THE ROLE OF THE GUT-BRAIN-AXIS IN SUBSTANCE USE DISORDERS: EVIDENCE FROM HUMAN GENETIC STUDIES Alcohol and Alcoholism. 50: i18.1-i18. DOI: 10.1093/Alcalc/Agv076.63 |
0.39 |
|
2015 |
Schank JR, Nelson BS, Damadzic R, Tapocik JD, Yao M, King CE, Rowe KE, Cheng K, Rice KC, Heilig M. Neurokinin-1 receptor antagonism attenuates neuronal activity triggered by stress-induced reinstatement of alcohol seeking Neuropharmacology. 99: 106-114. DOI: 10.1016/j.neuropharm.2015.07.009 |
0.331 |
|
2014 |
Spagnolo PA, Ramchandani VA, Schwandt ML, Zhang L, Blaine SK, Usala JM, Diamond KA, Phillips MJ, George DT, Momenan R, Heilig M. Effects of naltrexone on neural and subjective response to alcohol in treatment-seeking alcohol-dependent patients. Alcoholism, Clinical and Experimental Research. 38: 3024-32. PMID 25581657 DOI: 10.1111/Acer.12581 |
0.789 |
|
2014 |
Ciccocioppo R, Stopponi S, Economidou D, Kuriyama M, Kinoshita H, Heilig M, Roberto M, Weiss F, Teshima K. Chronic treatment with novel brain-penetrating selective NOP receptor agonist MT-7716 reduces alcohol drinking and seeking in the rat. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2601-10. PMID 24863033 DOI: 10.1038/Npp.2014.113 |
0.758 |
|
2014 |
Heilig M, Schank JR. Kappa-opioid receptor antagonism: a mechanism for treatment of relief drinking? Biological Psychiatry. 75: 750-1. PMID 24780009 DOI: 10.1016/J.Biopsych.2014.03.004 |
0.497 |
|
2014 |
Umhau JC, Schwandt M, Solomon MG, Yuan P, Nugent A, Zarate CA, Drevets WC, Hall SD, George DT, Heilig M. Cerebrospinal fluid monocyte chemoattractant protein-1 in alcoholics: support for a neuroinflammatory model of chronic alcoholism. Alcoholism, Clinical and Experimental Research. 38: 1301-6. PMID 24689518 DOI: 10.1111/Acer.12367 |
0.425 |
|
2014 |
Tapocik JD, Barbier E, Flanigan M, Solomon M, Pincus A, Pilling A, Sun H, Schank JR, King C, Heilig M. microRNA-206 in rat medial prefrontal cortex regulates BDNF expression and alcohol drinking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 4581-8. PMID 24672003 DOI: 10.1523/Jneurosci.0445-14.2014 |
0.354 |
|
2014 |
Spanagel R, Noori HR, Heilig M. Stress and alcohol interactions: animal studies and clinical significance. Trends in Neurosciences. 37: 219-27. PMID 24636458 DOI: 10.1016/J.Tins.2014.02.006 |
0.471 |
|
2014 |
Yong W, Spence JP, Eskay R, Fitz SD, Damadzic R, Lai D, Foroud T, Carr LG, Shekhar A, Chester JA, Heilig M, Liang T. Alcohol-preferring rats show decreased corticotropin-releasing hormone-2 receptor expression and differences in HPA activation compared to alcohol-nonpreferring rats. Alcoholism, Clinical and Experimental Research. 38: 1275-83. PMID 24611993 DOI: 10.1111/Acer.12379 |
0.476 |
|
2014 |
Huang MC, Schwandt ML, Chester JA, Kirchhoff AM, Kao CF, Liang T, Tapocik JD, Ramchandani VA, George DT, Hodgkinson CA, Goldman D, Heilig M. FKBP5 moderates alcohol withdrawal severity: human genetic association and functional validation in knockout mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2029-38. PMID 24603855 DOI: 10.1038/Npp.2014.55 |
0.42 |
|
2014 |
Heilig M. Acamprosate: an alcoholism treatment that may not be what we thought. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 781-2. PMID 24518272 DOI: 10.1038/Npp.2013.272 |
0.459 |
|
2014 |
Ciccocioppo R, de Guglielmo G, Hansson AC, Ubaldi M, Kallupi M, Cruz MT, Oleata CS, Heilig M, Roberto M. Restraint stress alters nociceptin/orphanin FQ and CRF systems in the rat central amygdala: significance for anxiety-like behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 363-72. PMID 24403138 DOI: 10.1523/Jneurosci.2400-13.2014 |
0.549 |
|
2014 |
Lee MR, Cacic K, Demers CH, Haroon M, Heishman S, Hommer DW, Epstein DH, Ross TJ, Stein EA, Heilig M, Salmeron BJ. Gender differences in neural-behavioral response to self-observation during a novel fMRI social stress task. Neuropsychologia. 53: 257-63. PMID 24316200 DOI: 10.1016/J.Neuropsychologia.2013.11.022 |
0.316 |
|
2014 |
Schank JR, King CE, Sun H, Cheng K, Rice KC, Heilig M, Weinshenker D, Schroeder JP. The role of the neurokinin-1 receptor in stress-induced reinstatement of alcohol and cocaine seeking. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1093-101. PMID 24173499 DOI: 10.1038/Npp.2013.309 |
0.473 |
|
2014 |
Cippitelli A, Damadzic R, Hamelink C, Brunnquell M, Thorsell A, Heilig M, Eskay RL. Binge-like ethanol consumption increases corticosterone levels and neurodegneration whereas occupancy of type II glucocorticoid receptors with mifepristone is neuroprotective. Addiction Biology. 19: 27-36. PMID 22500955 DOI: 10.1111/J.1369-1600.2012.00451.X |
0.391 |
|
2013 |
Patnaik S, Marugan JJ, Liu K, Zheng W, Southall N, Dehdashti SJ, Thorsell A, Heilig M, Bell L, Zook M, Eskay B, Brimacombe KR, Austin CP. Structure-activity relationship of imidazopyridinium analogues as antagonists of neuropeptide s receptor. Journal of Medicinal Chemistry. 56: 9045-56. PMID 24171469 DOI: 10.1021/Jm400904M |
0.306 |
|
2013 |
Zhou Z, Karlsson C, Liang T, Xiong W, Kimura M, Tapocik JD, Yuan Q, Barbier E, Feng A, Flanigan M, Augier E, Enoch MA, Hodgkinson CA, Shen PH, Lovinger DM, ... ... Heilig M, et al. Loss of metabotropic glutamate receptor 2 escalates alcohol consumption. Proceedings of the National Academy of Sciences of the United States of America. 110: 16963-8. PMID 24082084 DOI: 10.1073/Pnas.1309839110 |
0.487 |
|
2013 |
Björk K, Tronci V, Thorsell A, Tanda G, Hirth N, Heilig M, Hansson AC, Sommer WH. β-Arrestin 2 knockout mice exhibit sensitized dopamine release and increased reward in response to a low dose of alcohol. Psychopharmacology. 230: 439-49. PMID 23779257 DOI: 10.1007/S00213-013-3166-X |
0.468 |
|
2013 |
Thorsell A, Tapocik JD, Liu K, Zook M, Bell L, Flanigan M, Patnaik S, Marugan J, Damadzic R, Dehdashti SJ, Schwandt ML, Southall N, Austin CP, Eskay R, Ciccocioppo R, ... ... Heilig M, et al. A novel brain penetrant NPS receptor antagonist, NCGC00185684, blocks alcohol-induced ERK-phosphorylation in the central amygdala and decreases operant alcohol self-administration in rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 10132-42. PMID 23761908 DOI: 10.1523/Jneurosci.4742-12.2013 |
0.659 |
|
2013 |
Ayanwuyi LO, Carvajal F, Lerma-Cabrera JM, Domi E, Björk K, Ubaldi M, Heilig M, Roberto M, Ciccocioppo R, Cippitelli A. Role of a genetic polymorphism in the corticotropin-releasing factor receptor 1 gene in alcohol drinking and seeking behaviors of marchigian sardinian alcohol-preferring rats. Frontiers in Psychiatry. 4: 23. PMID 23630503 DOI: 10.3389/Fpsyt.2013.00023 |
0.658 |
|
2013 |
Stopponi S, de Guglielmo G, Somaini L, Cippitelli A, Cannella N, Kallupi M, Ubaldi M, Heilig M, Demopulos G, Gaitanaris G, Ciccocioppo R. Activation of PPARγ by pioglitazone potentiates the effects of naltrexone on alcohol drinking and relapse in msP rats. Alcoholism, Clinical and Experimental Research. 37: 1351-60. PMID 23550625 DOI: 10.1111/Acer.12091 |
0.655 |
|
2013 |
Schank JR, Tapocik JD, Barbier E, Damadzic R, Eskay RL, Sun H, Rowe KE, King CE, Yao M, Flanigan ME, Solomon MG, Karlsson C, Cheng K, Rice KC, Heilig M. Tacr1 gene variation and neurokinin 1 receptor expression is associated with antagonist efficacy in genetically selected alcohol-preferring rats. Biological Psychiatry. 73: 774-81. PMID 23419547 DOI: 10.1016/J.Biopsych.2012.12.027 |
0.5 |
|
2013 |
Mayo LM, Fraser D, Childs E, Momenan R, Hommer DW, de Wit H, Heilig M. Conditioned preference to a methamphetamine-associated contextual cue in humans. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 921-9. PMID 23416857 DOI: 10.1038/Npp.2013.3 |
0.634 |
|
2013 |
Meinhardt MW, Hansson AC, Perreau-Lenz S, Bauder-Wenz C, Stählin O, Heilig M, Harper C, Drescher KU, Spanagel R, Sommer WH. Rescue of infralimbic mGluR2 deficit restores control over drug-seeking behavior in alcohol dependence. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2794-806. PMID 23407939 DOI: 10.1523/Jneurosci.4062-12.2013 |
0.497 |
|
2013 |
Barbier E, Vendruscolo LF, Schlosburg JE, Edwards S, Juergens N, Park PE, Misra KK, Cheng K, Rice KC, Schank J, Schulteis G, Koob GF, Heilig M. The NK1 receptor antagonist L822429 reduces heroin reinforcement. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 976-84. PMID 23303056 DOI: 10.1038/Npp.2012.261 |
0.792 |
|
2013 |
Zorrilla EP, Heilig M, de Wit H, Shaham Y. Behavioral, biological, and chemical perspectives on targeting CRF(1) receptor antagonists to treat alcoholism. Drug and Alcohol Dependence. 128: 175-86. PMID 23294766 DOI: 10.1016/J.Drugalcdep.2012.12.017 |
0.746 |
|
2013 |
Schwandt ML, Heilig M, Hommer DW, George DT, Ramchandani VA. Childhood trauma exposure and alcohol dependence severity in adulthood: mediation by emotional abuse severity and neuroticism. Alcoholism, Clinical and Experimental Research. 37: 984-92. PMID 23278300 DOI: 10.1111/Acer.12053 |
0.404 |
|
2013 |
Herman MA, Kallupi M, Luu G, Oleata CS, Heilig M, Koob GF, Ciccocioppo R, Roberto M. Enhanced GABAergic transmission in the central nucleus of the amygdala of genetically selected Marchigian Sardinian rats: alcohol and CRF effects. Neuropharmacology. 67: 337-48. PMID 23220399 DOI: 10.1016/J.Neuropharm.2012.11.026 |
0.704 |
|
2013 |
Hirvonen J, Zanotti-Fregonara P, Umhau JC, George DT, Rallis-Frutos D, Lyoo CH, Li CT, Hines CS, Sun H, Terry GE, Morse C, Zoghbi SS, Pike VW, Innis RB, Heilig M. Reduced cannabinoid CB1 receptor binding in alcohol dependence measured with positron emission tomography. Molecular Psychiatry. 18: 916-21. PMID 22776901 DOI: 10.1038/Mp.2012.100 |
0.475 |
|
2013 |
Tapocik JD, Solomon M, Flanigan M, Meinhardt M, Barbier E, Schank JR, Schwandt M, Sommer WH, Heilig M. Coordinated dysregulation of mRNAs and microRNAs in the rat medial prefrontal cortex following a history of alcohol dependence. The Pharmacogenomics Journal. 13: 286-96. PMID 22614244 DOI: 10.1038/Tpj.2012.17 |
0.406 |
|
2013 |
Walsh SL, Heilig M, Nuzzo PA, Henderson P, Lofwall MR. Effects of the NK1 antagonist, aprepitant, on response to oral and intranasal oxycodone in prescription opioid abusers. Addiction Biology. 18: 332-43. PMID 22260216 DOI: 10.1111/J.1369-1600.2011.00419.X |
0.311 |
|
2013 |
Bartlett S, Heilig M. Translational approaches to medication development. Current Topics in Behavioral Neurosciences. 13: 543-82. PMID 21590390 DOI: 10.1007/978-3-642-28720-6_132 |
0.388 |
|
2013 |
Mayo LM, Momenan R, Heilig M, Harriet dW. C.21 - CHARACTERIZATION OF RESPONSES TO A CONDITIONED DRUG CUE IN HEALTHY, NON-DEPENDENT HUMANS Behavioural Pharmacology. 24: e36. DOI: 10.1097/01.Fbp.0000434805.81334.B3 |
0.551 |
|
2012 |
Schank JR, Ryabinin AE, Giardino WJ, Ciccocioppo R, Heilig M. Stress-related neuropeptides and addictive behaviors: beyond the usual suspects. Neuron. 76: 192-208. PMID 23040815 DOI: 10.1016/J.Neuron.2012.09.026 |
0.547 |
|
2012 |
Karlsson C, Zook M, Ciccocioppo R, Gehlert DR, Thorsell A, Heilig M, Cippitelli A. Melanin-concentrating hormone receptor 1 (MCH1-R) antagonism: reduced appetite for calories and suppression of addictive-like behaviors. Pharmacology, Biochemistry, and Behavior. 102: 400-6. PMID 22705492 DOI: 10.1016/J.Pbb.2012.06.010 |
0.561 |
|
2012 |
Vendruscolo LF, Barbier E, Schlosburg JE, Misra KK, Whitfield TW, Logrip ML, Rivier C, Repunte-Canonigo V, Zorrilla EP, Sanna PP, Heilig M, Koob GF. Corticosteroid-dependent plasticity mediates compulsive alcohol drinking in rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 7563-71. PMID 22649234 DOI: 10.1523/Jneurosci.0069-12.2012 |
0.829 |
|
2012 |
Schank JR, Goldstein AL, Rowe KE, King CE, Marusich JA, Wiley JL, Carroll FI, Thorsell A, Heilig M. The kappa opioid receptor antagonist JDTic attenuates alcohol seeking and withdrawal anxiety. Addiction Biology. 17: 634-47. PMID 22515275 DOI: 10.1111/J.1369-1600.2012.00455.X |
0.527 |
|
2012 |
Litten RZ, Egli M, Heilig M, Cui C, Fertig JB, Ryan ML, Falk DE, Moss H, Huebner R, Noronha A. Medications development to treat alcohol dependence: a vision for the next decade. Addiction Biology. 17: 513-27. PMID 22458728 DOI: 10.1111/J.1369-1600.2012.00454.X |
0.377 |
|
2012 |
Huang MC, Schwandt ML, Ramchandani VA, George DT, Heilig M. Impact of multiple types of childhood trauma exposure on risk of psychiatric comorbidity among alcoholic inpatients. Alcoholism, Clinical and Experimental Research. 36: 1099-107. PMID 22420670 DOI: 10.1111/J.1530-0277.2011.01695.X |
0.355 |
|
2012 |
Karlsson RM, Adermark L, Molander A, Perreau-Lenz S, Singley E, Solomon M, Holmes A, Tanaka K, Lovinger DM, Spanagel R, Heilig M. Reduced alcohol intake and reward associated with impaired endocannabinoid signaling in mice with a deletion of the glutamate transporter GLAST. Neuropharmacology. 63: 181-9. PMID 22342743 DOI: 10.1016/J.Neuropharm.2012.01.027 |
0.469 |
|
2012 |
Spinelli S, Schwandt ML, Lindell SG, Heilig M, Suomi SJ, Higley JD, Goldman D, Barr CS. The serotonin transporter gene linked polymorphic region is associated with the behavioral response to repeated stress exposure in infant rhesus macaques. Development and Psychopathology. 24: 157-65. PMID 22293001 DOI: 10.1017/S0954579411000745 |
0.306 |
|
2012 |
Molander A, Vengeliene V, Heilig M, Wurst W, Deussing JM, Spanagel R. Brain-specific inactivation of the Crhr1 gene inhibits post-dependent and stress-induced alcohol intake, but does not affect relapse-like drinking. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1047-56. PMID 22113086 DOI: 10.1038/Npp.2011.297 |
0.503 |
|
2012 |
Cippitelli A, Damadzic R, Singley E, Thorsell A, Ciccocioppo R, Eskay RL, Heilig M. Pharmacological blockade of corticotropin-releasing hormone receptor 1 (CRH1R) reduces voluntary consumption of high alcohol concentrations in non-dependent Wistar rats. Pharmacology, Biochemistry, and Behavior. 100: 522-9. PMID 22036774 DOI: 10.1016/J.Pbb.2011.10.016 |
0.658 |
|
2012 |
Chen CH, Walker J, Momenan R, Rawlings R, Heilig M, Hommer DW. Relationship between liver function and brain shrinkage in patients with alcohol dependence. Alcoholism, Clinical and Experimental Research. 36: 625-32. PMID 21995416 DOI: 10.1111/J.1530-0277.2011.01662.X |
0.399 |
|
2012 |
Robinson JE, Fish EW, Krouse MC, Thorsell A, Heilig M, Malanga CJ. Potentiation of brain stimulation reward by morphine: effects of neurokinin-1 receptor antagonism. Psychopharmacology. 220: 215-24. PMID 21909635 DOI: 10.1007/S00213-011-2469-Z |
0.583 |
|
2012 |
Snell LD, Ramchandani VA, Saba L, Herion D, Heilig M, George DT, Pridzun L, Helander A, Schwandt ML, Phillips MJ, Hoffman PL, Tabakoff B. The biometric measurement of alcohol consumption. Alcoholism, Clinical and Experimental Research. 36: 332-41. PMID 21895709 DOI: 10.1111/J.1530-0277.2011.01605.X |
0.4 |
|
2012 |
Magnusson Å, Lundholm C, Göransson M, Copeland W, Heilig M, Pedersen NL. Familial influence and childhood trauma in female alcoholism. Psychological Medicine. 42: 381-9. PMID 21798111 DOI: 10.1017/S0033291711001310 |
0.389 |
|
2011 |
Heilig M, Goldman D, Berrettini W, O'Brien CP. Pharmacogenetic approaches to the treatment of alcohol addiction. Nature Reviews. Neuroscience. 12: 670-84. PMID 22011682 DOI: 10.1038/Nrn3110 |
0.395 |
|
2011 |
Sinha R, Shaham Y, Heilig M. Translational and reverse translational research on the role of stress in drug craving and relapse. Psychopharmacology. 218: 69-82. PMID 21494792 DOI: 10.1007/S00213-011-2263-Y |
0.356 |
|
2011 |
Schwandt ML, Lindell SG, Higley JD, Suomi SJ, Heilig M, Barr CS. OPRM1 gene variation influences hypothalamic-pituitary-adrenal axis function in response to a variety of stressors in rhesus macaques. Psychoneuroendocrinology. 36: 1303-11. PMID 21459516 DOI: 10.1016/J.Psyneuen.2011.03.002 |
0.363 |
|
2011 |
Rinker JA, Hutchison MA, Chen SA, Thorsell A, Heilig M, Riley AL. Exposure to nicotine during periadolescence or early adulthood alters aversive and physiological effects induced by ethanol. Pharmacology, Biochemistry, and Behavior. 99: 7-16. PMID 21420998 DOI: 10.1016/J.Pbb.2011.03.009 |
0.6 |
|
2011 |
Schank JR, Pickens CL, Rowe KE, Cheng K, Thorsell A, Rice KC, Shaham Y, Heilig M. Stress-induced reinstatement of alcohol-seeking in rats is selectively suppressed by the neurokinin 1 (NK1) antagonist L822429. Psychopharmacology. 218: 111-9. PMID 21340476 DOI: 10.1007/S00213-011-2201-Z |
0.51 |
|
2011 |
Umhau JC, Schwandt ML, Usala J, Geyer C, Singley E, George DT, Heilig M. Pharmacologically induced alcohol craving in treatment seeking alcoholics correlates with alcoholism severity, but is insensitive to acamprosate. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 1178-86. PMID 21289601 DOI: 10.1038/Npp.2010.253 |
0.481 |
|
2011 |
Stopponi S, Somaini L, Cippitelli A, Cannella N, Braconi S, Kallupi M, Ruggeri B, Heilig M, Demopulos G, Gaitanaris G, Massi M, Ciccocioppo R. Activation of nuclear PPARγ receptors by the antidiabetic agent pioglitazone suppresses alcohol drinking and relapse to alcohol seeking. Biological Psychiatry. 69: 642-9. PMID 21276964 DOI: 10.1016/J.Biopsych.2010.12.010 |
0.661 |
|
2011 |
Hansson AC, Rimondini R, Heilig M, Mathé AA, Sommer WH. Dissociation of antidepressant-like activity of escitalopram and nortriptyline on behaviour and hippocampal BDNF expression in female rats. Journal of Psychopharmacology (Oxford, England). 25: 1378-87. PMID 21262856 DOI: 10.1177/0269881110393049 |
0.302 |
|
2011 |
Copeland WE, Magnusson A, Göransson M, Heilig MA. Genetic moderators and psychiatric mediators of the link between sexual abuse and alcohol dependence. Drug and Alcohol Dependence. 115: 183-9. PMID 21193270 DOI: 10.1016/j.drugalcdep.2010.10.024 |
0.306 |
|
2011 |
Cippitelli A, Rezvani AH, Robinson JE, Eisenberg L, Levin ED, Bonaventure P, Motley ST, Lovenberg TW, Heilig M, Thorsell A. The novel, selective, brain-penetrant neuropeptide Y Y2 receptor antagonist, JNJ-31020028, tested in animal models of alcohol consumption, relapse, and anxiety. Alcohol (Fayetteville, N.Y.). 45: 567-76. PMID 21145691 DOI: 10.1016/J.Alcohol.2010.09.003 |
0.586 |
|
2011 |
Breese GR, Sinha R, Heilig M. Chronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapse. Pharmacology & Therapeutics. 129: 149-71. PMID 20951730 DOI: 10.1016/J.Pharmthera.2010.09.007 |
0.482 |
|
2011 |
Heilig M, Warren KR, Kunos G, Silverman PB, Hewitt BG. Addiction research centres and the nurturing of creativity: the National Institute on Alcohol Abuse and Alcoholism. Addiction (Abingdon, England). 106: 1052-60. PMID 20569230 DOI: 10.1111/J.1360-0443.2010.02995.X |
0.433 |
|
2011 |
Ramchandani VA, Umhau J, Pavon FJ, Ruiz-Velasco V, Margas W, Sun H, Damadzic R, Eskay R, Schoor M, Thorsell A, Schwandt ML, Sommer WH, George DT, Parsons LH, Herscovitch P, ... ... Heilig M, et al. A genetic determinant of the striatal dopamine response to alcohol in men. Molecular Psychiatry. 16: 809-17. PMID 20479755 DOI: 10.1038/Mp.2010.56 |
0.672 |
|
2010 |
Kallupi M, Cannella N, Economidou D, Ubaldi M, Ruggeri B, Weiss F, Massi M, Marugan J, Heilig M, Bonnavion P, de Lecea L, Ciccocioppo R. Neuropeptide S facilitates cue-induced relapse to cocaine seeking through activation of the hypothalamic hypocretin system. Proceedings of the National Academy of Sciences of the United States of America. 107: 19567-72. PMID 20974945 DOI: 10.1073/Pnas.1004100107 |
0.662 |
|
2010 |
Umhau JC, Momenan R, Schwandt ML, Singley E, Lifshitz M, Doty L, Adams LJ, Vengeliene V, Spanagel R, Zhang Y, Shen J, George DT, Hommer D, Heilig M. Effect of acamprosate on magnetic resonance spectroscopy measures of central glutamate in detoxified alcohol-dependent individuals: a randomized controlled experimental medicine study. Archives of General Psychiatry. 67: 1069-77. PMID 20921123 DOI: 10.1001/Archgenpsychiatry.2010.125 |
0.437 |
|
2010 |
Cippitelli A, Zook M, Bell L, Damadzic R, Eskay RL, Schwandt M, Heilig M. Reversibility of object recognition but not spatial memory impairment following binge-like alcohol exposure in rats. Neurobiology of Learning and Memory. 94: 538-46. PMID 20849966 DOI: 10.1016/J.Nlm.2010.09.006 |
0.359 |
|
2010 |
Cippitelli A, Karlsson C, Shaw JL, Thorsell A, Gehlert DR, Heilig M. Suppression of alcohol self-administration and reinstatement of alcohol seeking by melanin-concentrating hormone receptor 1 (MCH1-R) antagonism in Wistar rats. Psychopharmacology. 211: 367-75. PMID 20628734 DOI: 10.1007/S00213-010-1891-Y |
0.52 |
|
2010 |
Björk K, Terasmaa A, Sun H, Thorsell A, Sommer WH, Heilig M. Ethanol-induced activation of AKT and DARPP-32 in the mouse striatum mediated by opioid receptors. Addiction Biology. 15: 299-303. PMID 20456289 DOI: 10.1111/J.1369-1600.2010.00212.X |
0.313 |
|
2010 |
Lindell SG, Schwandt ML, Sun H, Sparenborg JD, Björk K, Kasckow JW, Sommer WH, Goldman D, Higley JD, Suomi SJ, Heilig M, Barr CS. Functional NPY variation as a factor in stress resilience and alcohol consumption in rhesus macaques. Archives of General Psychiatry. 67: 423-31. PMID 20368518 DOI: 10.1001/Archgenpsychiatry.2010.23 |
0.469 |
|
2010 |
Hansson AC, Nixon K, Rimondini R, Damadzic R, Sommer WH, Eskay R, Crews FT, Heilig M. Long-term suppression of forebrain neurogenesis and loss of neuronal progenitor cells following prolonged alcohol dependence in rats. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 13: 583-93. PMID 20334723 DOI: 10.1017/S1461145710000246 |
0.444 |
|
2010 |
Magnusson A, Göransson M, Heilig M. Early onset alcohol dependence with high density of family history is not "male limited". Alcohol (Fayetteville, N.Y.). 44: 131-9. PMID 20193873 DOI: 10.1016/J.Alcohol.2010.01.001 |
0.424 |
|
2010 |
Heilig M, Egli M, Crabbe JC, Becker HC. Acute withdrawal, protracted abstinence and negative affect in alcoholism: are they linked? Addiction Biology. 15: 169-84. PMID 20148778 DOI: 10.1111/J.1369-1600.2009.00194.X |
0.48 |
|
2010 |
Leeman RF, Heilig M, Cunningham CL, Stephens DN, Duka T, O'Malley SS. Ethanol consumption: how should we measure it? Achieving consilience between human and animal phenotypes. Addiction Biology. 15: 109-24. PMID 20148775 DOI: 10.1111/J.1369-1600.2009.00192.X |
0.418 |
|
2010 |
Cippitelli A, Damadzic R, Frankola K, Goldstein A, Thorsell A, Singley E, Eskay RL, Heilig M. Alcohol-induced neurodegeneration, suppression of transforming growth factor-beta, and cognitive impairment in rats: prevention by group II metabotropic glutamate receptor activation. Biological Psychiatry. 67: 823-30. PMID 20132926 DOI: 10.1016/J.Biopsych.2009.12.018 |
0.4 |
|
2010 |
Schwandt ML, Lindell SG, Chen S, Higley JD, Suomi SJ, Heilig M, Barr CS. Alcohol response and consumption in adolescent rhesus macaques: life history and genetic influences. Alcohol (Fayetteville, N.Y.). 44: 67-80. PMID 20113875 DOI: 10.1016/J.Alcohol.2009.09.034 |
0.615 |
|
2010 |
Thorsell A, Schank JR, Singley E, Hunt SP, Heilig M. Neurokinin-1 receptors (NK1R:s), alcohol consumption, and alcohol reward in mice. Psychopharmacology. 209: 103-11. PMID 20112009 DOI: 10.1007/S00213-010-1775-1 |
0.485 |
|
2010 |
Cippitelli A, Damadzic R, Hansson AC, Singley E, Sommer WH, Eskay R, Thorsell A, Heilig M. Neuropeptide Y (NPY) suppresses yohimbine-induced reinstatement of alcohol seeking. Psychopharmacology. 208: 417-26. PMID 20012021 DOI: 10.1007/S00213-009-1741-Y |
0.498 |
|
2010 |
Heilig M, Thorsell A, Sommer WH, Hansson AC, Ramchandani VA, George DT, Hommer D, Barr CS. Translating the neuroscience of alcoholism into clinical treatments: from blocking the buzz to curing the blues. Neuroscience and Biobehavioral Reviews. 35: 334-44. PMID 19941895 DOI: 10.1016/J.Neubiorev.2009.11.018 |
0.499 |
|
2010 |
George DT, Herion DW, Jones CL, Phillips MJ, Hersh J, Hill D, Heilig M, Ramchandani VA, Geyer C, Spero DE, Singley ED, O'Malley SS, Bishai R, Rawlings RR, Kunos G. Rimonabant (SR141716) has no effect on alcohol self-administration or endocrine measures in nontreatment-seeking heavy alcohol drinkers. Psychopharmacology. 208: 37-44. PMID 19902183 DOI: 10.1007/S00213-009-1704-3 |
0.473 |
|
2010 |
Barr CS, Chen SA, Schwandt ML, Lindell SG, Sun H, Suomi SJ, Heilig M. Suppression of alcohol preference by naltrexone in the rhesus macaque: a critical role of genetic variation at the micro-opioid receptor gene locus. Biological Psychiatry. 67: 78-80. PMID 19748082 DOI: 10.1016/J.Biopsych.2009.07.026 |
0.601 |
|
2009 |
Ciccocioppo R, Gehlert DR, Ryabinin A, Kaur S, Cippitelli A, Thorsell A, Lê AD, Hipskind PA, Hamdouchi C, Lu J, Hembre EJ, Cramer J, Song M, McKinzie D, Morin M, ... ... Heilig M, et al. Stress-related neuropeptides and alcoholism: CRH, NPY, and beyond. Alcohol (Fayetteville, N.Y.). 43: 491-8. PMID 19913192 DOI: 10.1016/J.Alcohol.2009.08.003 |
0.655 |
|
2009 |
Pickens CL, Adams-Deutsch T, Nair SG, Navarre BM, Heilig M, Shaham Y. Effect of pharmacological manipulations of neuropeptide Y and corticotropin-releasing factor neurotransmission on incubation of conditioned fear. Neuroscience. 164: 1398-406. PMID 19800945 DOI: 10.1016/J.Neuroscience.2009.09.079 |
0.323 |
|
2009 |
Barr CS, Dvoskin RL, Gupte M, Sommer W, Sun H, Schwandt ML, Lindell SG, Kasckow JW, Suomi SJ, Goldman D, Higley JD, Heilig M. Functional CRH variation increases stress-induced alcohol consumption in primates. Proceedings of the National Academy of Sciences of the United States of America. 106: 14593-8. PMID 19706546 DOI: 10.1073/Pnas.0902863106 |
0.433 |
|
2009 |
Jerlhag E, Egecioglu E, Landgren S, Salomé N, Heilig M, Moechars D, Datta R, Perrissoud D, Dickson SL, Engel JA. Requirement of central ghrelin signaling for alcohol reward. Proceedings of the National Academy of Sciences of the United States of America. 106: 11318-23. PMID 19564604 DOI: 10.1073/Pnas.0812809106 |
0.453 |
|
2009 |
Cannella N, Economidou D, Kallupi M, Stopponi S, Heilig M, Massi M, Ciccocioppo R. Persistent increase of alcohol-seeking evoked by neuropeptide S: an effect mediated by the hypothalamic hypocretin system. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2125-34. PMID 19322167 DOI: 10.1038/Npp.2009.37 |
0.581 |
|
2009 |
Momenan R, Kerich M, Van K, Zhang Y, Hommer D, Heilig M. Relationship Between Cerebral Glutamate and the Brain Volume in Alcoholic Subjects Neuroimage. 47: S154. DOI: 10.1016/S1053-8119(09)71606-4 |
0.37 |
|
2008 |
Barr CS, Dvoskin RL, Yuan Q, Lipsky RH, Gupte M, Hu X, Zhou Z, Schwandt ML, Lindell SG, McKee M, Becker ML, Kling MA, Gold PW, Higley D, Heilig M, et al. CRH haplotype as a factor influencing cerebrospinal fluid levels of corticotropin-releasing hormone, hypothalamic-pituitary-adrenal axis activity, temperament, and alcohol consumption in rhesus macaques. Archives of General Psychiatry. 65: 934-44. PMID 18678798 DOI: 10.1001/Archpsyc.65.8.934 |
0.439 |
|
2008 |
Schwandt ML, Higley JD, Suomi SJ, Heilig M, Barr CS. Rapid tolerance and locomotor sensitization in ethanol-naïve adolescent rhesus macaques. Alcoholism, Clinical and Experimental Research. 32: 1217-28. PMID 18482160 DOI: 10.1111/J.1530-0277.2008.00676.X |
0.31 |
|
2008 |
Hansson AC, Rimondini R, Neznanova O, Sommer WH, Heilig M. Neuroplasticity in brain reward circuitry following a history of ethanol dependence. The European Journal of Neuroscience. 27: 1912-22. PMID 18412612 DOI: 10.1111/J.1460-9568.2008.06159.X |
0.306 |
|
2008 |
Economidou D, Hansson AC, Weiss F, Terasmaa A, Sommer WH, Cippitelli A, Fedeli A, Martin-Fardon R, Massi M, Ciccocioppo R, Heilig M. Dysregulation of nociceptin/orphanin FQ activity in the amygdala is linked to excessive alcohol drinking in the rat. Biological Psychiatry. 64: 211-8. PMID 18367152 DOI: 10.1016/J.Biopsych.2008.02.004 |
0.756 |
|
2008 |
George DT, Gilman J, Hersh J, Thorsell A, Herion D, Geyer C, Peng X, Kielbasa W, Rawlings R, Brandt JE, Gehlert DR, Tauscher JT, Hunt SP, Hommer D, Heilig M. Neurokinin 1 receptor antagonism as a possible therapy for alcoholism. Science (New York, N.Y.). 319: 1536-9. PMID 18276852 DOI: 10.1126/Science.1153813 |
0.498 |
|
2008 |
Huang J, Young B, Pletcher MT, Heilig M, Wahlestedt C. Association between the nociceptin receptor gene (OPRL1) single nucleotide polymorphisms and alcohol dependence. Addiction Biology. 13: 88-94. PMID 18269382 DOI: 10.1111/J.1369-1600.2007.00089.X |
0.412 |
|
2008 |
Karlsson RM, Choe JS, Cameron HA, Thorsell A, Crawley JN, Holmes A, Heilig M. The neuropeptide Y Y1 receptor subtype is necessary for the anxiolytic-like effects of neuropeptide Y, but not the antidepressant-like effects of fluoxetine, in mice. Psychopharmacology. 195: 547-57. PMID 17891380 DOI: 10.1007/S00213-007-0945-2 |
0.32 |
|
2008 |
Kakko J, von Wachenfeldt J, Svanborg KD, Lidström J, Barr CS, Heilig M. Mood and neuroendocrine response to a chemical stressor, metyrapone, in buprenorphine-maintained heroin dependence. Biological Psychiatry. 63: 172-7. PMID 17850768 DOI: 10.1016/J.Biopsych.2007.05.001 |
0.311 |
|
2008 |
Rimondini R, Sommer WH, Dall'Olio R, Heilig M. Long-lasting tolerance to alcohol following a history of dependence. Addiction Biology. 13: 26-30. PMID 17850416 DOI: 10.1111/J.1369-1600.2007.00079.X |
0.479 |
|
2008 |
Sommer WH, Rimondini R, Hansson AC, Hipskind PA, Gehlert DR, Barr CS, Heilig MA. Upregulation of voluntary alcohol intake, behavioral sensitivity to stress, and amygdala crhr1 expression following a history of dependence. Biological Psychiatry. 63: 139-45. PMID 17585886 DOI: 10.1016/j.biopsych.2007.01.010 |
0.396 |
|
2007 |
Spinelli S, Schwandt ML, Lindell SG, Newman TK, Heilig M, Suomi SJ, Higley JD, Goldman D, Barr CS. Association between the recombinant human serotonin transporter linked promoter region polymorphism and behavior in rhesus macaques during a separation paradigm. Development and Psychopathology. 19: 977-87. PMID 17931429 DOI: 10.1017/S095457940700048X |
0.303 |
|
2007 |
Heilig M, Koob GF. A key role for corticotropin-releasing factor in alcohol dependence. Trends in Neurosciences. 30: 399-406. PMID 17629579 DOI: 10.1016/J.Tins.2007.06.006 |
0.675 |
|
2007 |
Thorsell A, Johnson J, Heilig M. Effect of the adenosine A2a receptor antagonist 3,7-dimethyl-propargylxanthine on anxiety-like and depression-like behavior and alcohol consumption in Wistar Rats. Alcoholism, Clinical and Experimental Research. 31: 1302-7. PMID 17550371 DOI: 10.1111/J.1530-0277.2007.00425.X |
0.478 |
|
2007 |
Hansson AC, Cippitelli A, Sommer WH, Ciccocioppo R, Heilig M. Region-specific down-regulation of Crhr1 gene expression in alcohol-preferring msP rats following ad lib access to alcohol. Addiction Biology. 12: 30-4. PMID 17407495 DOI: 10.1111/J.1369-1600.2007.00050.X |
0.651 |
|
2007 |
Magnusson A, Göransson M, Heilig M. Hazardous alcohol users during pregnancy: psychiatric health and personality traits. Drug and Alcohol Dependence. 89: 275-81. PMID 17363194 DOI: 10.1016/J.Drugalcdep.2007.01.015 |
0.421 |
|
2007 |
Gehlert DR, Cippitelli A, Thorsell A, Lê AD, Hipskind PA, Hamdouchi C, Lu J, Hembre EJ, Cramer J, Song M, McKinzie D, Morin M, Ciccocioppo R, Heilig M. 3-(4-Chloro-2-morpholin-4-yl-thiazol-5-yl)-8-(1-ethylpropyl)-2,6-dimethyl-imidazo[1,2-b]pyridazine: a novel brain-penetrant, orally available corticotropin-releasing factor receptor 1 antagonist with efficacy in animal models of alcoholism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2718-26. PMID 17344409 DOI: 10.1523/Jneurosci.4985-06.2007 |
0.646 |
|
2007 |
Barr CS, Schwandt M, Lindell SG, Chen SA, Goldman D, Suomi SJ, Higley JD, Heilig M. Association of a functional polymorphism in the mu-opioid receptor gene with alcohol response and consumption in male rhesus macaques. Archives of General Psychiatry. 64: 369-76. PMID 17339526 DOI: 10.1001/Archpsyc.64.3.369 |
0.636 |
|
2007 |
Ciccocioppo R, Economidou D, Rimondini R, Sommer W, Massi M, Heilig M. Buprenorphine reduces alcohol drinking through activation of the nociceptin/orphanin FQ-NOP receptor system. Biological Psychiatry. 61: 4-12. PMID 16533497 DOI: 10.1016/J.Biopsych.2006.01.006 |
0.626 |
|
2007 |
Hansson AC, Bermúdez-Silva FJ, Malinen H, Hyytiä P, Sanchez-Vera I, Rimondini R, Rodriguez de Fonseca F, Kunos G, Sommer WH, Heilig M. Genetic impairment of frontocortical endocannabinoid degradation and high alcohol preference. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 117-26. PMID 16482090 DOI: 10.1038/Sj.Npp.1301034 |
0.511 |
|
2007 |
Ciccocioppo R, Heilig M. Reply Biological Psychiatry. 62: 702. DOI: 10.1016/j.biopsych.2007.02.013 |
0.35 |
|
2006 |
Hansson AC, Cippitelli A, Sommer WH, Fedeli A, Björk K, Soverchia L, Terasmaa A, Massi M, Heilig M, Ciccocioppo R. Variation at the rat Crhr1 locus and sensitivity to relapse into alcohol seeking induced by environmental stress. Proceedings of the National Academy of Sciences of the United States of America. 103: 15236-41. PMID 17015825 DOI: 10.1073/Pnas.0604419103 |
0.657 |
|
2006 |
Göransson M, Magnusson A, Heilig M. Identifying hazardous alcohol consumption during pregnancy: implementing a research-based model in real life. Acta Obstetricia Et Gynecologica Scandinavica. 85: 657-62. PMID 16752255 DOI: 10.1080/00016340600589677 |
0.371 |
|
2006 |
Heilig M, Egli M. Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms. Pharmacology & Therapeutics. 111: 855-76. PMID 16545872 DOI: 10.1016/J.Pharmthera.2006.02.001 |
0.46 |
|
2005 |
Spanagel R, Heilig M. Addiction and its brain science. Addiction (Abingdon, England). 100: 1813-22. PMID 16367982 DOI: 10.1111/J.1360-0443.2005.01260.X |
0.324 |
|
2005 |
Magnusson A, Göransson M, Heilig M. Unexpectedly high prevalence of alcohol use among pregnant Swedish women: failed detection by antenatal care and simple tools that improve detection. Journal of Studies On Alcohol. 66: 157-64. PMID 15957666 DOI: 10.15288/Jsa.2005.66.157 |
0.397 |
|
2005 |
Mottagui-Tabar S, Prince JA, Wahlestedt C, Zhu G, Goldman D, Heilig M. A novel single nucleotide polymorphism of the neuropeptide Y (NPY) gene associated with alcohol dependence. Alcoholism, Clinical and Experimental Research. 29: 702-7. PMID 15897713 DOI: 10.1097/01.Alc.0000164365.04961.B1 |
0.432 |
|
2005 |
Cippitelli A, Bilbao A, Hansson AC, del Arco I, Sommer W, Heilig M, Massi M, Bermúdez-Silva FJ, Navarro M, Ciccocioppo R, de Fonseca FR. Cannabinoid CB1 receptor antagonism reduces conditioned reinstatement of ethanol-seeking behavior in rats. The European Journal of Neuroscience. 21: 2243-51. PMID 15869521 DOI: 10.1111/J.1460-9568.2005.04056.X |
0.608 |
|
2005 |
Karlsson RM, Holmes A, Heilig M, Crawley JN. Anxiolytic-like actions of centrally-administered neuropeptide Y, but not galanin, in C57BL/6J mice. Pharmacology, Biochemistry, and Behavior. 80: 427-36. PMID 15740785 DOI: 10.1016/J.Pbb.2004.12.009 |
0.336 |
|
2005 |
Rimondini R, Thorsell A, Heilig M. Suppression of ethanol self-administration by the neuropeptide Y (NPY) Y2 receptor antagonist BIIE0246: evidence for sensitization in rats with a history of dependence. Neuroscience Letters. 375: 129-33. PMID 15670655 DOI: 10.1016/J.Neulet.2004.10.084 |
0.391 |
|
2005 |
Bart G, Kreek MJ, Ott J, LaForge KS, Proudnikov D, Pollak L, Heilig M. Increased attributable risk related to a functional mu-opioid receptor gene polymorphism in association with alcohol dependence in central Sweden. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 417-22. PMID 15525999 DOI: 10.1038/Sj.Npp.1300598 |
0.459 |
|
2005 |
Heilig M, Egli M. Models for alcohol dependence: A clinical perspective Drug Discovery Today: Disease Models. 2: 313-318. DOI: 10.1016/J.Ddmod.2005.11.004 |
0.451 |
|
2004 |
Heilig M, Sommer W. Functional genomics strategies to identify susceptibility genes and treatment targets in alcohol dependence. Neurotoxicity Research. 6: 363-72. PMID 15545019 DOI: 10.1007/Bf03033310 |
0.402 |
|
2004 |
Heilig M. The NPY system in stress, anxiety and depression. Neuropeptides. 38: 213-24. PMID 15337373 DOI: 10.1016/J.Npep.2004.05.002 |
0.366 |
|
2004 |
Kalisch R, Salomé N, Platzer S, Wigger A, Czisch M, Sommer W, Singewald N, Heilig M, Berthele A, Holsboer F, Landgraf R, Auer DP. High trait anxiety and hyporeactivity to stress of the dorsomedial prefrontal cortex: a combined phMRI and Fos study in rats. Neuroimage. 23: 382-91. PMID 15325386 DOI: 10.1016/J.Neuroimage.2004.06.012 |
0.355 |
|
2004 |
Göransson M, Faxelid E, Heilig M. Beliefs and reality: detection and prevention of high alcohol consumption in Swedish antenatal clinics. Acta Obstetricia Et Gynecologica Scandinavica. 83: 796-800. PMID 15315589 DOI: 10.1111/J.0001-6349.2004.00461.X |
0.327 |
|
2004 |
Mottagui-Tabar S, McCarthy S, Reinemund J, Andersson B, Wahlestedt C, Heilig M. Analysis of 5-hydroxytryptamine 2c receptor gene promoter variants as alcohol-dependence risk factors. Alcohol and Alcoholism (Oxford, Oxfordshire). 39: 380-5. PMID 15304380 DOI: 10.1093/Alcalc/Agh086 |
0.436 |
|
2004 |
Arlinde C, Sommer W, Björk K, Reimers M, Hyytiä P, Kiianmaa K, Heilig M. A cluster of differentially expressed signal transduction genes identified by microarray analysis in a rat genetic model of alcoholism. The Pharmacogenomics Journal. 4: 208-18. PMID 15052257 DOI: 10.1038/Sj.Tpj.6500243 |
0.424 |
|
2004 |
Ciccocioppo R, Economidou D, Fedeli A, Angeletti S, Weiss F, Heilig M, Massi M. Attenuation of ethanol self-administration and of conditioned reinstatement of alcohol-seeking behaviour by the antiopioid peptide nociceptin/orphanin FQ in alcohol-preferring rats. Psychopharmacology. 172: 170-8. PMID 14624331 DOI: 10.1007/S00213-003-1645-1 |
0.782 |
|
2004 |
Caberlotto L, Rimondini R, Hansson A, Eriksson S, Heilig M. Corticotropin-releasing hormone (CRH) mRNA expression in rat central amygdala in cannabinoid tolerance and withdrawal: evidence for an allostatic shift? Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 15-22. PMID 12968131 DOI: 10.1038/Sj.Npp.1300296 |
0.373 |
|
2004 |
Ciccocioppo R, Cippitelli A, Soverchia L, Ubaldi M, Heilig M, Sommer W, Arlinde C, Hansson A, Hyytia P, Fonseca Fd, Massi M. P13 FUNCTIONAL GENOMICS FOR TARGET GENE IDENTIFICATION IN ANIMAL MODELS OF ALCOHOL ABUSE: THE ROLE OF THE CANNABINOID CB1 RECEPTOR SYSTEM Behavioural Pharmacology. 15: A11-A12. DOI: 10.1097/00008877-200409000-00053 |
0.585 |
|
2004 |
Heilig M, Thorsell A, Rimondini R. CENTRAL NPY-Y2 RECEPTORS AS A TREATMENT TARGET FOR ALCOHOLISM. Alcoholism: Clinical & Experimental Research. 28: 77A. DOI: 10.1097/00000374-200408002-00423 |
0.437 |
|
2004 |
Sommer W, Arlinde C, Rimondini R, Heilig M. CANDIDATE TREATMENT TARGETS FOR ALCOHOLISM: LEADS FROM FUNCTIONAL GENOMICS APPROACHES. Alcoholism: Clinical & Experimental Research. 28: 54A. DOI: 10.1097/00000374-200408002-00282 |
0.367 |
|
2004 |
Fedeli A, Hansson A, Heilig M, Economidou D, Massi M, Ciccocioppo R. THE NOCICEPTIN/ORPHANIN FQ SYSTEM IS DIFFERENTIALLY REGULATED IN GENETICALLY SELECTED ALCOHOL PREFERRING MSP COMPARED TO WISTAR RATS. Alcoholism: Clinical & Experimental Research. 28: 17A. DOI: 10.1097/00000374-200408002-00064 |
0.603 |
|
2003 |
Göransson M, Magnusson A, Bergman H, Rydberg U, Heilig M. Fetus at risk: prevalence of alcohol consumption during pregnancy estimated with a simple screening method in Swedish antenatal clinics. Addiction (Abingdon, England). 98: 1513-20. PMID 14616177 DOI: 10.1046/J.1360-0443.2003.00498.X |
0.392 |
|
2003 |
Holmes A, Heilig M, Rupniak NM, Steckler T, Griebel G. Neuropeptide systems as novel therapeutic targets for depression and anxiety disorders. Trends in Pharmacological Sciences. 24: 580-8. PMID 14607081 DOI: 10.1016/J.Tips.2003.09.011 |
0.332 |
|
2003 |
Rimondini R, Sommer W, Heilig M. A temporal threshold for induction of persistent alcohol preference: behavioral evidence in a rat model of intermittent intoxication. Journal of Studies On Alcohol. 64: 445-9. PMID 12921185 DOI: 10.15288/Jsa.2003.64.445 |
0.476 |
|
2003 |
Kela J, Salmi P, Rimondini-Giorgini R, Heilig M, Wahlestedt C. Behavioural analysis of melanin-concentrating hormone in rats: evidence for orexigenic and anxiolytic properties. Regulatory Peptides. 114: 109-14. PMID 12832098 DOI: 10.1016/S0167-0115(03)00114-9 |
0.339 |
|
2003 |
Rimondini R, Agren G, Börjesson S, Sommer W, Heilig M. Persistent behavioral and autonomic supersensitivity to stress following prenatal stress exposure in rats. Behavioural Brain Research. 140: 75-80. PMID 12644280 DOI: 10.1016/S0166-4328(02)00273-5 |
0.324 |
|
2003 |
Pandey SC, Carr LG, Heilig M, Ilveskoski E, Thiele TE. Neuropeptide y and alcoholism: genetic, molecular, and pharmacological evidence. Alcoholism, Clinical and Experimental Research. 27: 149-54. PMID 12605064 DOI: 10.1097/01.Alc.0000052706.21367.0E |
0.477 |
|
2003 |
Zhu G, Pollak L, Mottagui-Tabar S, Wahlestedt C, Taubman J, Virkkunen M, Goldman D, Heilig M. NPY Leu7Pro and alcohol dependence in Finnish and Swedish populations. Alcoholism, Clinical and Experimental Research. 27: 19-24. PMID 12544000 DOI: 10.1111/J.1530-0277.2003.Tb02715.X |
0.445 |
|
2002 |
Heilig M, Forslund K, Asberg M, Rydberg U. The dual-diagnosis concept used by Swedish social workers: limited validity upon examination using a structured diagnostic approach. European Psychiatry : the Journal of the Association of European Psychiatrists. 17: 363-5. PMID 12457747 DOI: 10.1016/S0924-9338(02)00690-9 |
0.36 |
|
2002 |
Thorsell A, Rimondini R, Heilig M. Blockade of central neuropeptide Y (NPY) Y2 receptors reduces ethanol self-administration in rats. Neuroscience Letters. 332: 1-4. PMID 12377370 DOI: 10.1016/S0304-3940(02)00904-7 |
0.395 |
|
2002 |
Thorsell A, Heilig M. Diverse functions of neuropeptide Y revealed using genetically modified animals. Neuropeptides. 36: 182-93. PMID 12359508 DOI: 10.1054/Npep.2002.0897 |
0.428 |
|
2002 |
Heilig M, Thorsell A. Brain neuropeptide Y (NPY) in stress and alcohol dependence. Reviews in the Neurosciences. 13: 85-94. PMID 12013027 DOI: 10.1515/Revneuro.2002.13.1.85 |
0.464 |
|
2002 |
Möller C, Sommer W, Thorsell A, Rimondini R, Heilig M. Anxiogenic-like action of centrally administered glucagon-like peptide-1 in a punished drinking test. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 26: 119-22. PMID 11853101 DOI: 10.1016/S0278-5846(01)00223-8 |
0.345 |
|
2002 |
Thorsell A, Caberlotto L, Rimondini R, Heilig M. Leptin suppression of hypothalamic NPY expression and feeding, but not amygdala NPY expression and experimental anxiety. Pharmacology, Biochemistry, and Behavior. 71: 425-30. PMID 11830177 DOI: 10.1016/S0091-3057(01)00678-5 |
0.334 |
|
2002 |
Rimondini R, Arlinde C, Sommer W, Heilig M. Long-lasting increase in voluntary ethanol consumption and transcriptional regulation in the rat brain after intermittent exposure to alcohol. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 27-35. PMID 11772933 DOI: 10.1096/Fj.01-0593Com |
0.445 |
|
2002 |
Heilig M, Sommer W, Rimondini R, Arlinde C. From phenotype to genes and back: a functional genomics approach to alcohol dependence European Psychiatry. 17: 33-34. DOI: 10.1016/S0924-9338(02)80150-X |
0.375 |
|
2001 |
Caberlotto L, Thorsell A, Rimondini R, Sommer W, Hyytiä P, Heilig M. Differential expression of NPY and its receptors in alcohol-preferring AA and alcohol-avoiding ANA rats. Alcoholism, Clinical and Experimental Research. 25: 1564-9. PMID 11707630 DOI: 10.1111/J.1530-0277.2001.Tb02162.X |
0.495 |
|
2001 |
Sommer W, Arlinde C, Caberlotto L, Thorsell A, Hyytia P, Heilig M. Differential expression of diacylglycerol kinase iota and L18A mRNAs in the brains of alcohol-preferring AA and alcohol-avoiding ANA rats. Molecular Psychiatry. 6: 103-8; 5. PMID 11244494 DOI: 10.1038/Sj.Mp.4000823 |
0.432 |
|
2001 |
Sommer W, Möller C, Wiklund L, Thorsell A, Rimondini R, Nissbrandt H, Heilig M. Local 5,7-dihydroxytryptamine lesions of rat amygdala: release of punished drinking, unaffected plus-maze behavior and ethanol consumption. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 24: 430-40. PMID 11182538 DOI: 10.1016/S0893-133X(00)00210-4 |
0.385 |
|
2000 |
Thorsell A, Michalkiewicz M, Dumont Y, Quirion R, Caberlotto L, Rimondini R, Mathé AA, Heilig M. Behavioral insensitivity to restraint stress, absent fear suppression of behavior and impaired spatial learning in transgenic rats with hippocampal neuropeptide Y overexpression. Proceedings of the National Academy of Sciences of the United States of America. 97: 12852-7. PMID 11058155 DOI: 10.1073/Pnas.220232997 |
0.349 |
|
2000 |
Borràs E, Coutelle C, Rosell A, Fernández-Muixi F, Broch M, Crosas B, Hjelmqvist L, Lorenzo A, Gutiérrez C, Santos M, Szczepanek M, Heilig M, Quattrocchi P, Farrés J, Vidal F, et al. Genetic polymorphism of alcohol dehydrogenase in europeans: the ADH2*2 allele decreases the risk for alcoholism and is associated with ADH3*1. Hepatology (Baltimore, Md.). 31: 984-9. PMID 10733556 DOI: 10.1053/He.2000.5978 |
0.302 |
|
1999 |
Thorsell A, Carlsson K, Ekman R, Heilig M. Behavioral and endocrine adaptation, and up-regulation of NPY expression in rat amygdala following repeated restraint stress. Neuroreport. 10: 3003-7. PMID 10549813 DOI: 10.1097/00001756-199909290-00024 |
0.353 |
|
1999 |
Möller C, Sommer W, Thorsell A, Heilig M. Anxiogenic-like action of galanin after intra-amygdala administration in the rat. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 21: 507-12. PMID 10481834 DOI: 10.1016/S0893-133X(98)00102-X |
0.363 |
|
1998 |
Thorsell A, Svensson P, Wiklund L, Sommer W, Ekman R, Heilig M. Suppressed neuropeptide Y (NPY) mRNA in rat amygdala following restraint stress. Regulatory Peptides. 75: 247-54. PMID 9802416 DOI: 10.1016/S0167-0115(98)00075-5 |
0.324 |
|
1998 |
Ekman A, Nissbrandt H, Heilig M, Dijkstra D, Eriksson E. Central administration of dopamine D3 receptor antisense to rat: effects on locomotion, dopamine release and [3H]spiperone binding. Naunyn-Schmiedeberg's Archives of Pharmacology. 358: 342-50. PMID 9774222 DOI: 10.1007/Pl00005263 |
0.306 |
|
1997 |
Möller C, Wiklund L, Sommer W, Thorsell A, Heilig M. Decreased experimental anxiety and voluntary ethanol consumption in rats following central but not basolateral amygdala lesions. Brain Research. 760: 94-101. PMID 9237523 DOI: 10.1016/S0006-8993(97)00308-9 |
0.344 |
|
1997 |
Möller C, Wiklund L, Thorsell A, Hyytiä P, Heilig M. Decreased measures of experimental anxiety in rats bred for high alcohol preference. Alcoholism, Clinical and Experimental Research. 21: 656-60. PMID 9194920 DOI: 10.1111/J.1530-0277.1997.Tb03818.X |
0.44 |
|
1995 |
Heilig M. Antisense inhibition of neuropeptide Y (NPY)-Y1 receptor expression blocks the anxiolytic-like action of NPY in amygdala and paradoxically increases feeding. Regulatory Peptides. 59: 201-5. PMID 8584755 DOI: 10.1016/0167-0115(95)00103-I |
0.364 |
|
1995 |
Georgieva J, Heilig M, Nylander I, Herrera-Marschitz M, Terenius L. In vivo antisense inhibition of prodynorphin expression in rat striatum: dose-dependence and sequence specificity Neuroscience Letters. 192: 69-71. DOI: 10.1016/0304-3940(95)11592-K |
0.315 |
|
1994 |
Heilig M, Koob GF, Ekman R, Britton KT. Corticotropin-releasing factor and neuropeptide Y: role in emotional integration. Trends in Neurosciences. 17: 80-5. PMID 7512773 DOI: 10.1016/0166-2236(94)90079-5 |
0.553 |
|
1993 |
Pich EM, Koob GF, Heilig M, Menzaghi F, Vale W, Weiss F. Corticotropin-releasing factor release from the mediobasal hypothalamus of the rat as measured by microdialysis. Neuroscience. 55: 695-707. PMID 8413932 DOI: 10.1016/0306-4522(93)90435-I |
0.668 |
|
1993 |
Wahlestedt C, Pich EM, Koob GF, Yee F, Heilig M. Modulation of anxiety and neuropeptide Y-Y1 receptors by antisense oligodeoxynucleotides. Science (New York, N.Y.). 259: 528-31. PMID 8380941 DOI: 10.1126/Science.8380941 |
0.581 |
|
1993 |
Heilig M, McLeod S, Brot M, Heinrichs SC, Menzaghi F, Koob GF, Britton KT. Anxiolytic-like action of neuropeptide Y: mediation by Y1 receptors in amygdala, and dissociation from food intake effects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 8: 357-63. PMID 8099792 DOI: 10.1038/Npp.1993.35 |
0.709 |
|
1993 |
Bing O, Möller C, Engel JA, Söderpalm B, Heilig M. Anxiolytic-like action of centrally administered galanin. Neuroscience Letters. 164: 17-20. PMID 7512244 DOI: 10.1016/0304-3940(93)90846-D |
0.386 |
|
1992 |
Heilig M, McLeod S, Koob GK, Britton KT. Anxiolytic-like effect of neuropeptide Y (NPY), but not other peptides in an operant conflict test. Regulatory Peptides. 41: 61-9. PMID 1360689 DOI: 10.1016/0167-0115(92)90514-U |
0.316 |
|
1991 |
Heilig M, Edvinsson L, Wahlestedt C. Effects of intracerebroventricular D-myo-inositol-1,2,6-trisphosphate (PP56), a proposed neuropeptide Y (NPY) antagonist, on locomotor activity, food intake, central effects of NPY and NPY-receptor binding. European Journal of Pharmacology. 209: 27-32. PMID 1667639 DOI: 10.1016/0014-2999(91)90006-C |
0.348 |
|
1990 |
Wahlestedt C, Blendy JA, Kellar KJ, Heilig M, Widerlöv E, Ekman R. Electroconvulsive shocks increase the concentration of neocortical and hippocampal neuropeptide Y (NPY)-like immunoreactivity in the rat. Brain Research. 507: 65-8. PMID 2302581 DOI: 10.1016/0006-8993(90)90523-E |
0.312 |
|
1990 |
Wahlestedt C, Grundemar L, HÃ¥kanson R, Heilig M, Shen GH, Zukowska-Grojec Z, Reis DJ. Neuropeptide Y receptor subtypes, Y1 and Y2. Annals of the New York Academy of Sciences. 611: 7-26. PMID 2174225 DOI: 10.1111/J.1749-6632.1990.Tb48918.X |
0.321 |
|
1989 |
Heilig M, Söderpalm B, Engel JA, Widerlöv E. Centrally administered neuropeptide Y (NPY) produces anxiolytic-like effects in animal anxiety models. Psychopharmacology. 98: 524-9. PMID 2570434 DOI: 10.1007/Bf00441953 |
0.359 |
|
1989 |
Heilig M, Vecsei L, Widerlöv E. Opposite effects of centrally administered neuropeptide Y (NPY) on locomotor activity of spontaneously hypertensive (SH) and normal rats. Acta Physiologica Scandinavica. 137: 243-8. PMID 2559586 DOI: 10.1111/J.1748-1716.1989.Tb08745.X |
0.322 |
|
1989 |
Wahlestedt C, Ekman R, Heilig M, Widerlöv E. Effects of psychoactive drugs on delta sleep-inducing peptide concentrations in rat brain. European Journal of Pharmacology. 159: 285-9. PMID 2522052 DOI: 10.1016/0014-2999(89)90159-3 |
0.306 |
|
1988 |
Heilig M, Wahlestedt C, Ekman R, Widerlöv E. Antidepressant drugs increase the concentration of neuropeptide Y (NPY)-like immunoreactivity in the rat brain. European Journal of Pharmacology. 147: 465-7. PMID 2967771 DOI: 10.1016/0014-2999(88)90182-3 |
0.303 |
|
1988 |
Heilig M, Wahlestedt C, Widerlöv E. Neuropeptide Y (NPY)-induced suppression of activity in the rat: evidence for NPY receptor heterogeneity and for interaction with alpha-adrenoceptors. European Journal of Pharmacology. 157: 205-13. PMID 2852114 DOI: 10.1016/0014-2999(88)90384-6 |
0.328 |
|
1988 |
Widerlöv E, Heilig M, Ekman R, Wahlestedt C. Possible relationship between neuropeptide Y (NPY) and major depression – evidence from human and animal studies Nordisk Psykiatrisk Tidsskrift. 42: 131-137. DOI: 10.3109/08039488809103218 |
0.3 |
|
1987 |
Heilig M, Murison R. Intracerebroventricular neuropeptide Y protects against stress-induced gastric erosion in the rat. European Journal of Pharmacology. 137: 127-9. PMID 3609132 DOI: 10.1016/0014-2999(87)90191-9 |
0.313 |
|
1987 |
Heilig M, Murison R. Intracerebroventricular neuropeptide Y suppresses open field and home cage activity in the rat. Regulatory Peptides. 19: 221-31. PMID 3432602 DOI: 10.1016/0167-0115(87)90278-3 |
0.32 |
|
1987 |
Wahlestedt C, Skagerberg G, Ekman R, Heilig M, Sundler F, HÃ¥kanson R. Neuropeptide Y (NPY) in the area of the hypothalamic paraventricular nucleus activates the pituitary-adrenocortical axis in the rat. Brain Research. 417: 33-8. PMID 3040184 DOI: 10.1016/0006-8993(87)90176-4 |
0.32 |
|
Low-probability matches (unlikely to be authored by this person) |
2010 |
Stephens DN, Duka T, Crombag HS, Cunningham CL, Heilig M, Crabbe JC. Reward sensitivity: issues of measurement, and achieving consilience between human and animal phenotypes. Addiction Biology. 15: 145-68. PMID 20148777 DOI: 10.1111/J.1369-1600.2009.00193.X |
0.299 |
|
2017 |
Kalafateli AL, Vallöf D, Jörnulf JW, Heilig M, Jerlhag E. A cannabinoid receptor antagonist attenuates ghrelin-induced activation of the mesolimbic dopamine system in mice. Physiology & Behavior. 184: 211-219. PMID 29221808 DOI: 10.1016/J.Physbeh.2017.12.005 |
0.299 |
|
1990 |
Heilig M, Vècséi L, Wahlestedt C, Alling C, Widerlöv E. Effects of centrally administered neuropeptide Y (NPY) and NPY13-36 on the brain monoaminergic systems of the rat. Journal of Neural Transmission. General Section. 79: 193-208. PMID 2297403 DOI: 10.1007/Bf01245130 |
0.298 |
|
2019 |
Heilig M, Augier E. S.03.02 Molecular mechanisms of choosing alcohol over natural reward European Neuropsychopharmacology. 29: S7. DOI: 10.1016/j.euroneuro.2018.11.921 |
0.297 |
|
2010 |
McCoy JG, Marugan JJ, Liu K, Zheng W, Southall N, Huang W, Heilig M, Austin CP. Selective Modulation of Gq/Gs pathways by Naphtho Pyrano Pyrimidines as antagonists of the Neuropeptide S Receptor. Acs Chemical Neuroscience. 1: 559-574. PMID 21116448 DOI: 10.1021/Cn100040H |
0.297 |
|
1989 |
Vécsei L, Alling C, Heilig M, Widerlöv E. Effects of cysteamine and pantethine on open-field behavior, hypothalamic catecholamine concentrations, and somatostatin-induced barrel rotation in rats. Pharmacology, Biochemistry, and Behavior. 32: 629-35. PMID 2568000 DOI: 10.1016/0091-3057(89)90009-9 |
0.297 |
|
2021 |
Heilig M. Startrek: The Next Generation of Alcohol Researchers. A Perspective from Markus Heilig, 2019 Recipient of the ESBRA Manfred Lautenschläger-European Alcohol Research Award. Alcohol and Alcoholism (Oxford, Oxfordshire). PMID 33417665 DOI: 10.1093/alcalc/agaa140 |
0.296 |
|
2004 |
Bart G, Heilig M, LaForge KS, Pollak L, Leal SM, Ott J, Kreek MJ. Substantial attributable risk related to a functional mu-opioid receptor gene polymorphism in association with heroin addiction in central Sweden. Molecular Psychiatry. 9: 547-9. PMID 15037869 DOI: 10.1038/Sj.Mp.4001504 |
0.295 |
|
2009 |
Neznanova O, Björk K, Rimondini R, Hansson AC, Hyytiä P, Heilig M, Sommer WH. Acute ethanol challenge inhibits glycogen synthase kinase-3beta in the rat prefrontal cortex. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 12: 275-80. PMID 19007447 DOI: 10.1017/S1461145708009620 |
0.294 |
|
2021 |
Karlsson H, Persson E, Perini I, Yngve A, Heilig M, Tinghög G. Acute effects of alcohol on social and personal decision making. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34750564 DOI: 10.1038/s41386-021-01218-9 |
0.294 |
|
2009 |
Wahlberg K, Ghatan PH, Modell S, Nygren A, Ingvar M, Asberg M, Heilig M. Suppressed neuroendocrine stress response in depressed women on job-stress-related long-term sick leave: a stable marker potentially suggestive of preexisting vulnerability. Biological Psychiatry. 65: 742-7. PMID 19058782 DOI: 10.1016/J.Biopsych.2008.10.035 |
0.292 |
|
2006 |
Thorsell A, Karlsson RM, Heilig M. NPY in alcoholism and psychiatric disorders. Exs. 183-92. PMID 16383007 DOI: 10.1007/3-7643-7417-9_14 |
0.29 |
|
1998 |
Bing O, Heilig M, Kakoulidis P, Sundblad C, Wiklund L, Eriksson E. High doses of testosterone increase anticonflict behaviour in rat. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 8: 321-3. PMID 9928924 DOI: 10.1016/S0924-977X(97)00095-3 |
0.289 |
|
2010 |
Skinbjerg M, Liow JS, Seneca N, Hong J, Lu S, Thorsell A, Heilig M, Pike VW, Halldin C, Sibley DR, Innis RB. D2 dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine: a PET study in a receptor internalization-deficient mouse model. Neuroimage. 50: 1402-7. PMID 20097293 DOI: 10.1016/J.Neuroimage.2010.01.055 |
0.288 |
|
2022 |
Sommer WH, Canals S, Bifone A, Heilig M, Hyytiä P. From a systems view to spotting a hidden island: A narrative review implicating insula function in alcoholism. Neuropharmacology. 209: 108989. PMID 35217032 DOI: 10.1016/j.neuropharm.2022.108989 |
0.288 |
|
2003 |
Kakko J, Svanborg KD, Kreek MJ, Heilig M. 1-year retention and social function after buprenorphine-assisted relapse prevention treatment for heroin dependence in Sweden: a randomised, placebo-controlled trial. Lancet. 361: 662-8. PMID 12606177 DOI: 10.1016/S0140-6736(03)12600-1 |
0.286 |
|
2011 |
Mahmoud S, Thorsell A, Sommer WH, Heilig M, Holgate JK, Bartlett SE, Ruiz-Velasco V. Pharmacological consequence of the A118G μ opioid receptor polymorphism on morphine- and fentanyl-mediated modulation of Ca²⺠channels in humanized mouse sensory neurons. Anesthesiology. 115: 1054-62. PMID 21926562 DOI: 10.1097/Aln.0B013E318231Fc11 |
0.286 |
|
2019 |
Persson E, Asutay E, Heilig M, Löfberg A, Pedersen N, Västfjäll D, Tinghög G. Variation in the μ-Opioid Receptor Gene ( OPRM1) Does Not Moderate Social-Rejection Sensitivity in Humans. Psychological Science. 956797619849894. PMID 31180793 DOI: 10.1177/0956797619849894 |
0.285 |
|
1993 |
Heilig M, Engel JA, Söderpalm B. C-fos antisense in the nucleus accumbens blocks the locomotor stimulant action of cocaine. European Journal of Pharmacology. 236: 339-40. PMID 8319761 DOI: 10.1016/0014-2999(93)90610-T |
0.284 |
|
2010 |
Sommer WH, Lidström J, Sun H, Passer D, Eskay R, Parker SC, Witt SH, Zimmermann US, Nieratschker V, Rietschel M, Margulies EH, Palkovits M, Laucht M, Heilig M. Human NPY promoter variation rs16147:T>C as a moderator of prefrontal NPY gene expression and negative affect. Human Mutation. 31: E1594-608. PMID 20648632 DOI: 10.1002/Humu.21299 |
0.283 |
|
2021 |
Van Booven D, Mengying Li, Sunil Rao J, Blokhin IO, Dayne Mayfield R, Barbier E, Heilig M, Wahlestedt C. Alcohol use disorder causes global changes in splicing in the human brain. Translational Psychiatry. 11: 2. PMID 33414398 DOI: 10.1038/s41398-020-01163-z |
0.282 |
|
1996 |
Thorsell A, Blomqvist AG, Heilig M. Cationic lipid-mediated delivery and expression of prepro-neuropeptide Y cDNA after intraventricular administration in rat: feasibility and limitations. Regulatory Peptides. 61: 205-11. PMID 8701037 DOI: 10.1016/0167-0115(95)00161-1 |
0.281 |
|
2010 |
Spinelli S, Chefer S, Carson RE, Jagoda E, Lang L, Heilig M, Barr CS, Suomi SJ, Higley JD, Stein EA. Effects of early-life stress on serotonin(1A) receptors in juvenile Rhesus monkeys measured by positron emission tomography. Biological Psychiatry. 67: 1146-53. PMID 20172506 DOI: 10.1016/J.Biopsych.2009.12.030 |
0.281 |
|
1997 |
Svenningsson P, Georgieva J, Kontny E, Heilig M, Fredholm BB. Involvement of a c-fos-dependent mechanism in caffeine-induced expression of the preprotachykinin A and neurotensin/neuromedin N genes in rat striatum. The European Journal of Neuroscience. 9: 2135-41. PMID 9421173 DOI: 10.1111/J.1460-9568.1997.Tb01380.X |
0.279 |
|
2006 |
Rydmark I, Wahlberg K, Ghatan PH, Modell S, Nygren A, Ingvar M, Asberg M, Heilig M. Neuroendocrine, cognitive and structural imaging characteristics of women on longterm sickleave with job stress-induced depression. Biological Psychiatry. 60: 867-73. PMID 16934773 DOI: 10.1016/J.Biopsych.2006.04.029 |
0.279 |
|
1997 |
Heilig M. [When does alcohol trigger violence? "Emotional blindness" and impulsiveness are important links]. Lã¤Kartidningen. 94: 841-4. PMID 9102510 |
0.277 |
|
2008 |
Barr CS, Schwandt ML, Lindell SG, Higley JD, Maestripieri D, Goldman D, Suomi SJ, Heilig M. Variation at the mu-opioid receptor gene (OPRM1) influences attachment behavior in infant primates. Proceedings of the National Academy of Sciences of the United States of America. 105: 5277-81. PMID 18378897 DOI: 10.1073/Pnas.0710225105 |
0.276 |
|
1996 |
Bing O, Heilig M, Kakaoulidis P, Sundblad C, Eriksson E. Anticonflict effect of high doses of testosterone in male wistar rats European Neuropsychopharmacology. 6: 77-78. DOI: 10.1016/0924-977X(96)87657-7 |
0.274 |
|
2016 |
Heilig M, Epstein DH, Nader MA, Shaham Y. Time to connect: bringing social context into addiction neuroscience. Nature Reviews. Neuroscience. PMID 27277868 DOI: 10.1038/Nrn.2016.67 |
0.274 |
|
2019 |
Spagnolo PA, Kimes A, Schwandt ML, Shokri-Kojori E, Thada S, Phillips KA, Diazgranados N, Preston KL, Herscovitch P, Tomasi D, Ramchandani VA, Heilig M. Striatal Dopamine Release in Response to Morphine: A [C]-Raclopride Positron Emission Tomography Study in Healthy Men. Biological Psychiatry. PMID 31097294 DOI: 10.1016/J.Biopsych.2019.03.965 |
0.273 |
|
2010 |
Schwandt ML, Lindell SG, Sjöberg RL, Chisholm KL, Higley JD, Suomi SJ, Heilig M, Barr CS. Gene-environment interactions and response to social intrusion in male and female rhesus macaques. Biological Psychiatry. 67: 323-30. PMID 20015482 DOI: 10.1016/J.Biopsych.2009.10.016 |
0.272 |
|
2018 |
Schroeder JR, Phillips KA, Epstein DH, Jobes ML, Furnari MA, Kennedy AP, Heilig M, Preston KL. Assessment of pioglitazone and proinflammatory cytokines during buprenorphine taper in patients with opioid use disorder. Psychopharmacology. PMID 30079432 DOI: 10.1007/S00213-018-4986-5 |
0.271 |
|
2016 |
Bernardi RE, Zohsel K, Hirth N, Treutlein J, Heilig M, Laucht M, Spanagel R, Sommer WH. A gene-by-sex interaction for nicotine reward: evidence from humanized mice and epidemiology. Translational Psychiatry. 6. PMID 27459726 DOI: 10.1038/Tp.2016.132 |
0.27 |
|
2007 |
Kakko J, Grönbladh L, Svanborg KD, von Wachenfeldt J, Rück C, Rawlings B, Nilsson LH, Heilig M. A stepped care strategy using buprenorphine and methadone versus conventional methadone maintenance in heroin dependence: a randomized controlled trial. The American Journal of Psychiatry. 164: 797-803. PMID 17475739 DOI: 10.1176/Ajp.2007.164.5.797 |
0.27 |
|
2009 |
Skinbjerg M, Ariano MA, Thorsell A, Heilig M, Halldin C, Innis RB, Sibley DR. Arrestin3 mediates D(2) dopamine receptor internalization. Synapse (New York, N.Y.). 63: 621-4. PMID 19309759 DOI: 10.1002/Syn.20636 |
0.269 |
|
2004 |
Heilig M, Zachrisson O, Thorsell A, Ehnvall A, Mottagui-Tabar S, Sjögren M, Asberg M, Ekman R, Wahlestedt C, Agren H. Decreased cerebrospinal fluid neuropeptide Y (NPY) in patients with treatment refractory unipolar major depression: preliminary evidence for association with preproNPY gene polymorphism. Journal of Psychiatric Research. 38: 113-21. PMID 14757324 DOI: 10.1016/S0022-3956(03)00101-8 |
0.267 |
|
2019 |
Boehme R, Hauser S, Gerling GJ, Heilig M, Olausson H. Distinction of self-produced touch and social touch at cortical and spinal cord levels. Proceedings of the National Academy of Sciences of the United States of America. PMID 30670645 DOI: 10.1073/Pnas.1816278116 |
0.267 |
|
2018 |
Hamilton JP, Sacchet MD, Hjørnevik T, Chin FT, Shen B, Kämpe R, Park JH, Knutson BD, Williams LM, Borg N, Zaharchuk G, Camacho MC, Mackey S, Heilig M, Drevets WC, et al. Striatal dopamine deficits predict reductions in striatal functional connectivity in major depression: a concurrent C-raclopride positron emission tomography and functional magnetic resonance imaging investigation. Translational Psychiatry. 8: 264. PMID 30504860 DOI: 10.1038/S41398-018-0316-2 |
0.264 |
|
2004 |
Heilig M. Brain neuropeptide Y (NPY) system: a candidate target for treatment of anxiety, depression and alcohol dependence Drugs of the Future. 29: 137. DOI: 10.1358/DOF.2004.029.02.850944 |
0.263 |
|
2006 |
Björk K, Saarikoski ST, Arlinde C, Kovanen L, Osei-Hyiaman D, Ubaldi M, Reimers M, Hyytiä P, Heilig M, Sommer WH. Glutathione-S-transferase expression in the brain: possible role in ethanol preference and longevity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1826-35. PMID 16940154 DOI: 10.1096/fj.06-5896com |
0.263 |
|
2021 |
Harel M, Perini I, Kämpe R, Alyagon U, Shalev H, Besser I, Sommer WH, Heilig M, Zangen A. Repetitive Transcranial Magnetic Stimulation in Alcohol Dependence: A Randomized, Double-Blind, Sham-Controlled Proof-of-Concept Trial Targeting the Medial Prefrontal and Anterior Cingulate Cortices. Biological Psychiatry. PMID 35067356 DOI: 10.1016/j.biopsych.2021.11.020 |
0.263 |
|
2023 |
Selim MK, Harel M, De Santis S, Perini I, Sommer WH, Heilig M, Zangen A, Canals S. Repetitive deep TMS in alcohol dependent patients halts progression of white matter changes in early abstinence. Psychiatry and Clinical Neurosciences. PMID 38085120 DOI: 10.1111/pcn.13624 |
0.262 |
|
2001 |
Thorsell A, Gruber SH, Mathé AA, Heilig M. Neuropeptide Y (NPY) mRNA in rat brain tissue: effects of decapitation and high-energy microwave irradiation on post mortem stability. Neuropeptides. 35: 168-73. PMID 11884207 DOI: 10.1054/Npep.2001.0860 |
0.262 |
|
2018 |
Epstein DH, Heilig M, Shaham Y. Science-Based Actions Can Help Address the Opioid Crisis. Trends in Pharmacological Sciences. 39: 911-916. PMID 30343726 DOI: 10.1016/J.Tips.2018.06.002 |
0.26 |
|
2000 |
Sommer W, Hebb MO, Heilig M. Pharmacokinetic properties of oligonucleotides in brain. Methods in Enzymology. 314: 261-75. PMID 10565019 DOI: 10.1016/S0076-6879(99)14109-0 |
0.26 |
|
2001 |
Wicks S, Hammar J, Heilig M, Wisén O. Factors Affecting the Short-Term Prognosis of Alcohol Dependent Patients Undergoing Inpatient Detoxification. Substance Abuse : Official Publication of the Association For Medical Education and Research in Substance Abuse. 22: 235-245. PMID 12466683 DOI: 10.1080/08897070109511465 |
0.257 |
|
2008 |
Karlsson RM, Tanaka K, Heilig M, Holmes A. Loss of glial glutamate and aspartate transporter (excitatory amino acid transporter 1) causes locomotor hyperactivity and exaggerated responses to psychotomimetics: rescue by haloperidol and metabotropic glutamate 2/3 agonist. Biological Psychiatry. 64: 810-4. PMID 18550032 DOI: 10.1016/J.Biopsych.2008.05.001 |
0.257 |
|
2012 |
Heilig M. Our focus on the pharmacogenetics of CRF 1 antagonists is simply because they are in clinical development Nature Reviews Neuroscience. 13: 70. DOI: 10.1038/Nrn3110-C2 |
0.256 |
|
2009 |
Karlsson RM, Tanaka K, Saksida LM, Bussey TJ, Heilig M, Holmes A. Assessment of glutamate transporter GLAST (EAAT1)-deficient mice for phenotypes relevant to the negative and executive/cognitive symptoms of schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1578-89. PMID 19078949 DOI: 10.1038/Npp.2008.215 |
0.255 |
|
2018 |
Perini I, Gustafsson PA, Hamilton JP, Kämpe R, Zetterqvist M, Heilig M. The salience of self, not social pain, is encoded by dorsal anterior cingulate and insula. Scientific Reports. 8: 6165. PMID 29670166 DOI: 10.1038/S41598-018-24658-8 |
0.255 |
|
1987 |
HÃ¥kanson R, Beding B, Ekman R, Heilig M, Wahlestedt C, Sundler F. Multiple tachykinin pools in sensory nerve fibres in the rabbit iris. Neuroscience. 21: 943-50. PMID 2442656 DOI: 10.1016/0306-4522(87)90049-2 |
0.252 |
|
2004 |
Sommer W, Arlinde C, Rimondini R, Hansson AC, Hyytiä P, deFonseca FR, Heilig M. S.20.01 Candidate genes for substance dependence:Evidence from expression profiling studies European Neuropsychopharmacology. 14. DOI: 10.1016/S0924-977X(04)80061-0 |
0.251 |
|
2005 |
Sommer W, Arlinde C, Heilig M. The search for candidate genes of alcoholism: evidence from expression profiling studies. Addiction Biology. 10: 71-9. PMID 15849021 DOI: 10.1080/13556210412331327821 |
0.25 |
|
2022 |
Lasserre AM, Imtiaz S, Roerecke M, Heilig M, Probst C, Rehm J. Socioeconomic status, alcohol use disorders, and depression: a population-based study. Journal of Affective Disorders. PMID 34986374 DOI: 10.1016/j.jad.2021.12.132 |
0.249 |
|
1998 |
Sommer W, Cui X, Erdmann B, Wiklund L, Bricca G, Heilig M, Fuxe K. The spread and uptake pattern of intracerebrally administered oligonucleotides in nerve and glial cell populations of the rat brain. Antisense & Nucleic Acid Drug Development. 8: 75-85. PMID 9593045 DOI: 10.1089/Oli.1.1998.8.75 |
0.247 |
|
2020 |
Boehme R, Frost Karlsson M, Heilig M, Olausson H, Capusan AJ. Sharpened self-other distinction in attention deficit hyperactivity disorder. Neuroimage. Clinical. 27: 102317. PMID 32599550 DOI: 10.1016/J.Nicl.2020.102317 |
0.246 |
|
2010 |
Blom ES, Wang Y, Skoglund L, Hansson AC, Ubaldi M, Lourdusamy A, Sommer WH, Mielke M, Hyman BT, Heilig M, Lannfelt L, Nilsson LN, Ingelsson M. Increased mRNA Levels of TCF7L2 and MYC of the Wnt Pathway in Tg-ArcSwe Mice and Alzheimer's Disease Brain. International Journal of Alzheimer's Disease. 2011: 936580. PMID 21234373 DOI: 10.4061/2011/936580 |
0.245 |
|
2004 |
Holmes A, Griebel G, Heilig M, Steckler T. Response to Roesler et al.: Neuropeptides and stress-related disorders – multiple targets and converging concepts Trends in Pharmacological Sciences. 25: 242-243. DOI: 10.1016/J.Tips.2004.03.006 |
0.241 |
|
2000 |
Blennow K, Bogdanovic N, Heilig M, Grenfeldt B, Karlsson I, Davidsson P. Reduction of the synaptic protein rab3a in the thalamus and connecting brain regions in post-mortem schizophrenic brains. Journal of Neural Transmission (Vienna, Austria : 1996). 107: 1085-97. PMID 11041284 DOI: 10.1007/S007020070054 |
0.24 |
|
1995 |
Bing O, Grundemar L, Ny L, Möller C, Heilig M. Modulation of carbon monoxide production and enhanced spatial learning by tin protoporphyrin. Neuroreport. 6: 1369-72. PMID 7488726 DOI: 10.1097/00001756-199507100-00002 |
0.239 |
|
1996 |
Ekman A, Nissbrandt H, Heilig M, Eriksson E. Behavioural and biochemical effects of dopamine D3 antisense administration European Neuropsychopharmacology. 6: 140-141. DOI: 10.1016/0924-977X(96)87953-3 |
0.236 |
|
1996 |
Erlinge D, Heilig M, Edvinsson L. Tyrphostin inhibition of ATP-stimulated DNA synthesis, cell proliferation and fos-protein expression in vascular smooth muscle cells. British Journal of Pharmacology. 118: 1028-34. PMID 8799578 DOI: 10.1111/J.1476-5381.1996.Tb15502.X |
0.236 |
|
2019 |
Filipčić I, Šimunović Filipčić I, Milovac Ž, Sučić S, Gajšak T, Ivezić E, Bašić S, Bajić Ž, Heilig M. Efficacy of repetitive transcranial magnetic stimulation using a figure-8-coil or an H1-Coil in treatment of major depressive disorder; A randomized clinical trial. Journal of Psychiatric Research. 114: 113-119. PMID 31059991 DOI: 10.1016/J.Jpsychires.2019.04.020 |
0.23 |
|
2006 |
Blom ES, Sommer WH, Hansson AC, Heilig M, Ubaldi M, Lourdusamy AA, Lannfelt L, Ingelsson M, Nilsson LNG. P1-030: Analysis of gene expression in brains of tg-APP-ArcSwe mice, a model for Alzheimer’s disease Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.405 |
0.222 |
|
1996 |
Ekman R, Juhasz P, Heilig M, Agren H, Costello CE. Novel neuropeptide Y processing in human cerebrospinal fluid from depressed patients. Peptides. 17: 1107-11. PMID 8959743 DOI: 10.1016/S0196-9781(96)00168-4 |
0.221 |
|
2008 |
Blom ES, Wang Y, Hansson A, Sommer W, Hyman BT, Heilig M, Lannfelt L, Nisson LNG, Ingelsson M. P3-205: Upregulation of genes in the Wnt pathway in tg-ArcSwe mice and Alzheimer's disease brain Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1772 |
0.219 |
|
2008 |
Kakko J, Heilig M, Sarman I. Buprenorphine and methadone treatment of opiate dependence during pregnancy: comparison of fetal growth and neonatal outcomes in two consecutive case series. Drug and Alcohol Dependence. 96: 69-78. PMID 18355989 DOI: 10.1016/J.Drugalcdep.2008.01.025 |
0.218 |
|
1996 |
Nilsson C, Karlsson G, Blennow K, Heilig M, Ekman R. Differences in the neuropeptide Y-like immunoreactivity of the plasma and platelets of human volunteers and depressed patients. Peptides. 17: 359-62. PMID 8735959 DOI: 10.1016/0196-9781(96)00013-7 |
0.218 |
|
2003 |
Heilig M. Maintenance buprenorphine for opioid users The Lancet. 361: 1907-1908. DOI: 10.1016/S0140-6736(03)13514-3 |
0.216 |
|
2005 |
Reimers M, Heilig M, Sommer WH. Gene discovery in neuropharmacological and behavioral studies using Affymetrix microarray data. Methods (San Diego, Calif.). 37: 219-28. PMID 16308151 DOI: 10.1016/J.Ymeth.2005.09.002 |
0.215 |
|
2018 |
Spagnolo PA, Wang H, Srivanitchapoom P, Schwandt M, Heilig M, Hallett M. Lack of Target Engagement Following Low-Frequency Deep Transcranial Magnetic Stimulation of the Anterior Insula. Neuromodulation : Journal of the International Neuromodulation Society. PMID 30370983 DOI: 10.1111/Ner.12875 |
0.21 |
|
2015 |
Heilig M, Carlezon WA. Circumspectives: Cannabis and Psychiatric Illness: Blunt Thoughts. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26555278 DOI: 10.1038/Npp.2015.321 |
0.21 |
|
2002 |
Rimondini R, Sommer W, Heilig M. Effects of tiagabine and diazepam on operant ethanol self-administration in the rat. Journal of Studies On Alcohol. 63: 100-6. PMID 11925051 |
0.209 |
|
2004 |
Rodr??guez de Fonseca F, Bilbao A, Cippitelli A, del Arco I, Javier Berm??dez-Silva F, Cicoccioppo R, Heilig M, Hansson A, Hyytia P. CANDIDATE GENES FROM TARGALC MICROARRAY STUDIES: THE CANNABINOID SYSTEM. Alcoholism: Clinical & Experimental Research. 28: 57A. DOI: 10.1097/00000374-200408002-00302 |
0.205 |
|
2024 |
Pietrzak M, Yngve A, Hamilton JP, Asratian A, Gauffin E, Löfberg A, Gustavson S, Persson E, Capusan AJ, Leggio L, Perini I, Tinghög G, Heilig M, Boehme R. Ghrelin decreases sensitivity to negative feedback and increases prediction-error related caudate activity in humans, a randomized controlled trial. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 38409282 DOI: 10.1038/s41386-024-01821-6 |
0.202 |
|
2007 |
Sommer WH, Rimondini R, Marquitz M, Lidström J, Siems WE, Bader M, Heilig M. Plasticity and impact of the central renin-angiotensin system during development of ethanol dependence. Journal of Molecular Medicine (Berlin, Germany). 85: 1089-97. PMID 17823780 DOI: 10.1007/s00109-007-0255-5 |
0.201 |
|
2007 |
Heilig M. Imagen: implications for addiction science and science policy. Addiction (Abingdon, England). 102: 1699-700. PMID 17935578 DOI: 10.1111/J.1360-0443.2007.02004.X |
0.201 |
|
2013 |
Umhau JC, George DT, Heaney RP, Lewis MD, Ursano RJ, Heilig M, Hibbeln JR, Schwandt ML. Low vitamin D status and suicide: a case-control study of active duty military service members. Plos One. 8: e51543. PMID 23308099 DOI: 10.1371/Journal.Pone.0051543 |
0.2 |
|
1994 |
Möller C, Bing O, Heilig M. c-fos expression in the amygdala: in vivo antisense modulation and role in anxiety. Cellular and Molecular Neurobiology. 14: 415-23. PMID 7621504 |
0.194 |
|
2015 |
Heilig M, Carlezon WA. Circumspectives: The Replacements. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1813-4. PMID 26068571 DOI: 10.1038/Npp.2015.82 |
0.192 |
|
1985 |
Heilig M. Cholecystokinin (CCK) in the nervous system (Ellis Horwood health science series) Regulatory Peptides. 11: 185-186. DOI: 10.1016/0167-0115(85)90080-1 |
0.19 |
|
2013 |
Umhau JC, George DT, Heaney RP, Lewis MD, Ursano RJ, Heilig M, Hibbeln JR, Schwandt ML. Correction: Low Vitamin D Status and Suicide: A Case-Control Study of Active Duty Military Service Members Plos One. 8. DOI: 10.1371/Annotation/9Af84Cbe-5576-4C4B-871C-F7Ab0C64B9Fd |
0.186 |
|
2007 |
Heilig M. Dr. Heilig Replies American Journal of Psychiatry. 164: 1757-1758. PMID 22688229 DOI: 10.1176/Appi.Ajp.2007.07071058R |
0.186 |
|
2008 |
Björk K, Rimondini R, Hansson AC, Terasmaa A, Hyytiä P, Heilig M, Sommer WH. Modulation of voluntary ethanol consumption by beta-arrestin 2. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 2552-60. PMID 18367649 DOI: 10.1096/fj.07-102442 |
0.184 |
|
2014 |
Augier E, Flanigan M, Dulman RS, Pincus A, Schank JR, Rice KC, Kejun C, Heilig M, Tapocik JD. Wistar rats acquire and maintain self-administration of 20 % ethanol without water deprivation, saccharin/sucrose fading, or extended access training. Psychopharmacology. 231: 4561-8. PMID 24858375 DOI: 10.1007/S00213-014-3605-3 |
0.181 |
|
1996 |
Heilig M, MÃ¥nsson JE, Blennow K. Cerebrospinal fluid monoamine metabolites and atmospheric pressure. Biological Psychiatry. 39: 299-301. PMID 8645778 DOI: 10.1016/0006-3223(95)00475-0 |
0.179 |
|
2011 |
Heilig M. A welcome change that stops short of being fully satisfying. Addiction (Abingdon, England). 106: 874-5; discussion 89. PMID 21477231 DOI: 10.1111/J.1360-0443.2010.03233.X |
0.178 |
|
1995 |
Heilig M, Ekman R. Chronic parenteral antidepressant treatment in rats: unaltered levels and processing of neuropeptide Y (NPY) and corticotropin-releasing hormone (CRH). Neurochemistry International. 26: 351-5. PMID 7633328 |
0.178 |
|
2008 |
Heilig M. Triggering addiction Scientist. 22: 30-35. |
0.177 |
|
1996 |
Blennow K, Davidsson P, Gottfries CG, Ekman R, Heilig M. Synaptic degeneration in thalamus in schizophrenia. Lancet. 348: 692-3. PMID 8782788 DOI: 10.1016/S0140-6736(05)65124-0 |
0.173 |
|
2011 |
Sreedharan S, Almén MS, Carlini VP, Haitina T, Stephansson O, Sommer WH, Heilig M, de Barioglio SR, Fredriksson R, Schiöth HB. The G protein coupled receptor Gpr153 shares common evolutionary origin with Gpr162 and is highly expressed in central regions including the thalamus, cerebellum and the arcuate nucleus. The Febs Journal. 278: 4881-94. PMID 21981325 DOI: 10.1111/j.1742-4658.2011.08388.x |
0.172 |
|
2001 |
Smiałowska M, Bajkowska M, Heilig M, Obuchowicz E, Turchan J, Maj M, Przewłocki R. Pharmacological studies on the monoaminergic influence on the synthesis and expression of neuropeptide Y and corticotropin releasing factor in rat brain amygdala. Neuropeptides. 35: 82-91. PMID 11384203 DOI: 10.1054/npep.2001.0849 |
0.172 |
|
2020 |
Venniro M, Banks ML, Heilig M, Epstein DH, Shaham Y. Improving translation of animal models of addiction and relapse by reverse translation. Nature Reviews. Neuroscience. PMID 33024318 DOI: 10.1038/s41583-020-0378-z |
0.172 |
|
2003 |
Heilig M, Forslund K, Åsberg M, Rydberg U. El concepto de diagnóstico dual utilizado por los trabajadores sociales suecos tiene validez limitada en un examen que utiliza un enfoque diagnóstico estructurado European Psychiatry (Ed. EspañOla). 10: 123-126. DOI: 10.1017/s1134066500006676 |
0.164 |
|
2022 |
Heilig M, Barbier E. Cycles of addiction and loneliness. Neuron. 110: 4035-4037. PMID 36549267 DOI: 10.1016/j.neuron.2022.12.002 |
0.159 |
|
2021 |
Heilig M, MacKillop J, Martinez D, Rehm J, Leggio L, Vanderschuren LJMJ. Addiction as a brain disease revised: why it still matters, and the need for consilience. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 33619327 DOI: 10.1038/s41386-020-00950-y |
0.148 |
|
1995 |
Nissbrandt H, Ekman A, Eriksson E, Heilig M. Dopamine D3 receptor antisense influences dopamine synthesis in rat brain. Neuroreport. 6: 573-6. PMID 7766866 |
0.147 |
|
2022 |
Løseth GE, Eikemo M, Trøstheim M, Meier IM, Bjørnstad H, Asratian A, Pazmandi C, Tangen VW, Heilig M, Leknes S. Stress recovery with social support: A dyadic stress and support task. Psychoneuroendocrinology. 146: 105949. PMID 36240542 DOI: 10.1016/j.psyneuen.2022.105949 |
0.144 |
|
1990 |
Heilig M, Widerlöv E. Neuropeptide Y: an overview of central distribution, functional aspects, and possible involvement in neuropsychiatric illnesses. Acta Psychiatrica Scandinavica. 82: 95-114. PMID 2173355 |
0.143 |
|
1995 |
Heilig M, Widerlöv E. Neurobiology and clinical aspects of neuropeptide Y. Critical Reviews in Neurobiology. 9: 115-36. PMID 8581979 |
0.135 |
|
2021 |
Klawonn AM, Fritz M, Castany S, Pignatelli M, Canal C, Similä F, Tejeda HA, Levinsson J, Jaarola M, Jakobsson J, Hidalgo J, Heilig M, Bonci A, Engblom D. Microglial activation elicits a negative affective state through prostaglandin-mediated modulation of striatal neurons. Immunity. PMID 33476547 DOI: 10.1016/j.immuni.2020.12.016 |
0.133 |
|
2023 |
Pietrzak M, Yngve A, Hamilton JP, Kämpe R, Boehme R, Asratian A, Gauffin E, Löfberg A, Gustavson S, Persson E, Capusan AJ, Leggio L, Perini I, Tinghög G, Heilig M. A randomized controlled experimental medicine study of ghrelin in value-based decision making. The Journal of Clinical Investigation. PMID 37040196 DOI: 10.1172/JCI168260 |
0.13 |
|
2017 |
Bejerot S, Landén M, Heilig M, Anckarsäter H, Waern M. Lakartidningen. 114. PMID 29292910 |
0.12 |
|
2022 |
Skoglund C, Leknes S, Heilig M. The partial µ-opioid agonist buprenorphine in autism spectrum disorder: a case report. Journal of Medical Case Reports. 16: 152. PMID 35422015 DOI: 10.1186/s13256-022-03384-w |
0.119 |
|
1999 |
Thorsell A, Fox E, Heilig M. Lipid mediated gene delivery in the adult rat brain: quantitative analysis of expression. Neurochemistry International. 35: 65-71. PMID 10403431 DOI: 10.1016/S0197-0186(99)00034-0 |
0.119 |
|
2002 |
Heilig M. [Documented effect of methadone, but not naltrexone]. Lã¤Kartidningen. 99: 551-2. PMID 11881232 |
0.117 |
|
2022 |
Löfberg A, Gustafsson PA, Gauffin E, Perini I, Heilig M, Capusan AJ. Assessing Childhood Maltreatment Exposure in Patients Without and With a Diagnosis of Substance Use Disorder. Journal of Addiction Medicine. 17: 263-270. PMID 37267165 DOI: 10.1097/ADM.0000000000001091 |
0.113 |
|
2022 |
Löfberg A, Gustafsson PA, Gauffin E, Perini I, Heilig M, Capusan AJ. Assessing Childhood Maltreatment Exposure in Patients Without and With a Diagnosis of Substance Use Disorder. Journal of Addiction Medicine. 17: 263-270. PMID 37267165 DOI: 10.1097/ADM.0000000000001091 |
0.113 |
|
2002 |
Heilig M. [Surprising conclusion by the SBU concerning the benefits of naltrexone in the treatment of heroin dependence]. Lã¤Kartidningen. 99: 200-4. PMID 11838078 |
0.108 |
|
2023 |
Paul ER, Östman L, Heilig M, Mayberg HS, Hamilton JP. Towards a multilevel model of major depression: genes, immuno-metabolic function, and cortico-striatal signaling. Translational Psychiatry. 13: 171. PMID 37208333 DOI: 10.1038/s41398-023-02466-7 |
0.106 |
|
2011 |
Copeland WE, Sun H, Costello EJ, Angold A, Heilig MA, Barr CS. Child μ-opioid receptor gene variant influences parent-child relations. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 1165-70. PMID 21326192 DOI: 10.1038/Npp.2010.251 |
0.103 |
|
1995 |
Gottfries CG, Frederiksen SO, Heilig M. Neuropeptides and Alzheimer's disease. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 5: 491-500. PMID 8998402 |
0.103 |
|
2021 |
Bäckryd E, Heilig M, Hoffmann M. Opioid availability statistics from the International Narcotics Control Board do not reflect the medical use of opioids: comparison with sales data from Scandinavia. Scandinavian Journal of Pain. PMID 34315195 DOI: 10.1515/sjpain-2021-0023 |
0.102 |
|
2017 |
Bäckryd E, Heilig M, Hoffmann M. Lakartidningen. 114. PMID 28485763 |
0.102 |
|
2024 |
Sangchooli A, Zare-Bidoky M, Fathi Jouzdani A, Schacht J, Bjork JM, Claus ED, Prisciandaro JJ, Wilson SJ, Wüstenberg T, Potvin S, Ahmadi P, Bach P, Baldacchino A, Beck A, Brady KT, ... ... Heilig M, et al. Parameter Space and Potential for Biomarker Development in 25 Years of fMRI Drug Cue Reactivity: A Systematic Review. Jama Psychiatry. PMID 38324323 DOI: 10.1001/jamapsychiatry.2023.5483 |
0.1 |
|
2001 |
Heilig M, Nilsson LH, Grönbladh L, Thulin SO, Sternebring B. [Use of a new drug in the treatment of heroin addicts should not be obstructed by political dogmatism]. Lã¤Kartidningen. 98: 3956-8. PMID 11586837 |
0.099 |
|
1995 |
Heilig M, Sjögren M, Blennow K, Ekman R, Wallin A. Cerebrospinal fluid neuropeptides in Alzheimer's disease and vascular dementia. Biological Psychiatry. 38: 210-6. PMID 8547442 DOI: 10.1016/0006-3223(94)00239-Y |
0.099 |
|
1999 |
Sommer W, Heilig M. [Antisense oligonucleotides are clinically tested. They inhibit the expression of disease-related genes]. Lã¤Kartidningen. 96: 348-54. PMID 10024826 |
0.095 |
|
2013 |
Heilig M. [Opioid dependence: New national guidelines must allow maintenance treatment]. Lã¤Kartidningen. 110: 1908-9. PMID 24340431 |
0.094 |
|
2022 |
Paul ER, Schwieler L, Erhardt S, Boda S, Trepci A, Kämpe R, Asratian A, Holm L, Yngve A, Dantzer R, Heilig M, Hamilton JP, Samuelsson M. Peripheral and central kynurenine pathway abnormalities in major depression. Brain, Behavior, and Immunity. 101: 136-145. PMID 34999196 DOI: 10.1016/j.bbi.2022.01.002 |
0.092 |
|
2002 |
Heilig M, Oreland L, Ekman R, Akerstedt T, Nygren A. [The brain behind stress and fatigue depression]. Lã¤Kartidningen. 99: 2515-8. PMID 12092052 |
0.086 |
|
2008 |
Heilig M, Gunne L. [New guidelines against unfair treatment of narcotic addicts necessary]. Lã¤Kartidningen. 105: 3093-4. PMID 19031975 |
0.084 |
|
2001 |
Heilig M. [A welcomed SBU report shows efficient methods against abuse. But certain parts are already out of date]. Lã¤Kartidningen. 98: 3903-4. PMID 11586828 |
0.084 |
|
2010 |
Liu K, Southall N, Titus SA, Inglese J, Eskay RL, Shinn P, Austin CP, Heilig MA, Zheng W. A multiplex calcium assay for identification of GPCR agonists and antagonists. Assay and Drug Development Technologies. 8: 367-79. PMID 20230302 DOI: 10.1089/Adt.2009.0245 |
0.083 |
|
2023 |
Hansen JL, Heilig M, Kalso E, Stubhaug A, Knutsson D, Sandin P, Dorling P, Beck C, Grip ET, Blakeman KH, Arendt-Nielsen L. Problematic opioid use among osteoarthritis patients with chronic post-operative pain after joint replacement: analyses from the BISCUITS study. Scandinavian Journal of Pain. PMID 36799711 DOI: 10.1515/sjpain-2022-0137 |
0.082 |
|
2021 |
Heilig M, MacKillop J, Martinez D, Rehm J, Leggio L, Vanderschuren LJMJ. Response to "Addiction is a social disease: just as tenable as calling it a brain disease". Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34108632 DOI: 10.1038/s41386-021-01037-y |
0.081 |
|
1997 |
Grewal IS, Heilig M, Miller A, Sercarz EE. Environmental regulation of T-cell function in mice: group housing of males affects accessory cell function. Immunology. 90: 165-8. PMID 9135542 DOI: 10.1046/J.1365-2567.1997.00190.X |
0.077 |
|
1999 |
Heilig M. [Substance dependence is easier to prevent than to treat. But is early identification of individuals at risk and aimed prevention ethically justified?]. Lã¤Kartidningen. 96: 1796-801. PMID 10319639 |
0.076 |
|
2003 |
Heilig M, Kakko J. [Reduced drug craving and better social function with buprenorphine therapy. Combination therapy as an alternative to methadone therapy in heroin addiction]. Lã¤Kartidningen. 100: 2526-7. PMID 12959012 |
0.075 |
|
1995 |
Georgieva J, Nylander I, Heilig M, Herrera-Marschitz M, Terenius L. IN VIVO ANTISENSE INHIBITION OF PRODYNORPHIN GENE EXPRESSION Analgesia. 1: 433-437. DOI: 10.3727/107156995819563339 |
0.065 |
|
1994 |
Heilig M. [Neuropeptides affect emotional life. New discoveries on the function of the peptide system]. Lã¤Kartidningen. 91: 2585-9. PMID 8046978 |
0.065 |
|
2003 |
Heilig M. [Ecstasy is a dangerous drug the society chooses to ignore]. Lã¤Kartidningen. 100: 688-90. PMID 12674555 |
0.063 |
|
2020 |
Persson E, Heilig M, Tinghög G, Capusan AJ. Using quantitative trait in adults with ADHD to test predictions of dual-process theory. Scientific Reports. 10: 20076. PMID 33208789 DOI: 10.1038/s41598-020-76923-4 |
0.063 |
|
2014 |
Heilig M, Bäuml D, Fürll M. [Potential involvement of selenium in the occurrence of milk fever in cattle]. TieräRztliche Praxis. Ausgabe G, Grosstiere/Nutztiere. 42: 261-70. PMID 25327148 |
0.063 |
|
2022 |
Bäckryd E, Heilig M, Hoffmann M. Comment on Häuser et al.: Medical use of opioids in Europe-Methodological concerns about data from the International Narcotics Control Board. European Journal of Pain (London, England). PMID 35108428 DOI: 10.1002/ejp.1919 |
0.06 |
|
2015 |
Schroeder C, Faust U, Sturm M, Hackmann K, Grundmann K, Harmuth F, Bosse K, Kehrer M, Benkert T, Klink B, Mackenroth L, Betcheva-Krajcir E, Wimberger P, Kast K, Heilig M, et al. HBOC multi-gene panel testing: comparison of two sequencing centers. Breast Cancer Research and Treatment. 152: 129-36. PMID 26022348 DOI: 10.1007/s10549-015-3429-9 |
0.056 |
|
2014 |
Chlond B, Weiss C, Heilig M, Vortisch P. Hybrid modeling approach of car uses in Germany on basis of empirical data with different granularities Transportation Research Record. 67-74. DOI: 10.3141/2412-08 |
0.056 |
|
2010 |
Heilig M, Zander D, Olson D, Mishra B, Hort N, Klaus G, Buehrig-Polaczek A, Gröbner J, Schmid-Fetzer R. Influence of cerium on stress corrosion cracking in AZ91D Magnesium Technology. 305-309. |
0.052 |
|
2003 |
Heilig MR, Matern RV, Rosenzweig SD, Bennett JT. Current management of idiopathic clubfoot questionnaire: a multicentric study. Journal of Pediatric Orthopedics. 23: 780-7. PMID 14581783 |
0.052 |
|
2013 |
Worgull M, Schneider M, Röhrig M, Meier T, Heilig M, Kolew A, Feit K, Hölscher H, Leuthold J. Hot embossing and thermoforming of biodegradable three-dimensional wood structures Rsc Advances. 3: 20060-20064. DOI: 10.1039/C3Ra42642D |
0.051 |
|
2000 |
Sommer W, Arlinde C, Caberlotto L, Thorsell A, Hyytia P, Heilig M. CNS expression of diacylglycerol kinase iota and L18A mRNAs Molecular Psychiatry. 6: 5-5. DOI: 10.1038/SJ.MP.4000831 |
0.043 |
|
2018 |
Yuan Y, Heilig M, Jung S, Rietdorf E, Weidhaas J. MicroRNA-138 Regulation of PD-L1 Expression Immediately after Radiation is Altered by the rs4742098 Variant International Journal of Radiation Oncology*Biology*Physics. 102: S156. DOI: 10.1016/J.IJROBP.2018.06.376 |
0.042 |
|
2011 |
Huang YL, Heilig M, Hasse H, Vrabec J. Vapor-liquid equilibria of hydrogen chloride, phosgene, benzene, chlorobenzene, ortho-dichlorobenzene, and toluene by molecular simulation Aiche Journal. 57: 1043-1060. DOI: 10.1002/Aic.12329 |
0.04 |
|
2023 |
Kämpe R, Paul ER, Östman L, Heilig M, Howard DM, Hamilton JP. Contributions of polygenic risk and disease status to grey matter abnormalities in major depression. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. PMID 38142967 DOI: 10.1016/j.bpsc.2023.12.001 |
0.039 |
|
2011 |
Heilig M, Huber S, Gerken J, Demarmels M, Allmendinger K, Reiterer H. Hidden details of negotiation: The mechanics of reality-based collaboration in information seeking Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 6947: 622-639. DOI: 10.1007/978-3-642-23771-3_46 |
0.035 |
|
1993 |
Heilig M, Irwin M, Grewal I, Sercarz E. Sympathetic regulation of T-helper cell function. Brain, Behavior, and Immunity. 7: 154-63. PMID 8394164 DOI: 10.1006/brbi.1993.1017 |
0.033 |
|
2022 |
Barchiesi R, Chanthongdee K, Petrella M, Xu L, Söderholm S, Domi E, Augier G, Coppola A, Wiskerke J, Szczot I, Domi A, Adermark L, Augier E, Cantù C, Heilig M, et al. Correction: An epigenetic mechanism for over-consolidation of fear memories. Molecular Psychiatry. PMID 36319842 DOI: 10.1038/s41380-022-01827-w |
0.033 |
|
2012 |
Huang YL, Merker T, Heilig M, Hasse H, Vrabec J. Molecular modeling and simulation of vapor-liquid equilibria of ethylene oxide, ethylene glycol, and water as well as their binary mixtures Industrial and Engineering Chemistry Research. 51: 7428-7440. DOI: 10.1021/Ie300248Z |
0.032 |
|
1998 |
Heilig M. [Benzodiazepines are just a tool in the clinical work. Different opinions are both right and wrong]. Lã¤Kartidningen. 95: 3628-9. PMID 9748769 |
0.031 |
|
2016 |
Schauer S, Meier T, Reinhard M, Röhrig M, Schneider M, Heilig M, Kolew A, Worgull M, Hölscher H. Tunable Diffractive Optical Elements based on Shape-Memory Polymers fabricated via Hot Embossing. Acs Applied Materials & Interfaces. PMID 26998646 DOI: 10.1021/acsami.6b00679 |
0.03 |
|
2022 |
Ljungvall H, Lind AL, Zetterberg H, Wagner S, Ekselius L, Karlsten R, Heilig M, Åsenlöf P. U-PAIN cohort study among patients with chronic pain in specialised pain care: a feasibility study. Bmj Open. 12: e062265. PMID 36517106 DOI: 10.1136/bmjopen-2022-062265 |
0.026 |
|
2012 |
Albers K, Heilig M, Sadowski G. Reducing the amount of PCP-SAFT fitting parameters. 2. Associating components Fluid Phase Equilibria. 326: 31-44. DOI: 10.1016/j.fluid.2012.04.014 |
0.025 |
|
2003 |
Adolfsson R, Bejerot S, Engel J, Forssberg H, Heilig M, Humble M, Ingvar M, Levander S, Oreland L, Pedersen N, Asberg M, Ohman A. [Researchers and psychiatrists defending Gillberg's research on ADDH: Karfve's campaign is a form of personal persecution and scientific basis is missing]. LäKartidningen. 100: 636-7. PMID 12640980 |
0.025 |
|
2008 |
Port H, Rath S, Heilig M, Gärtner P. Regular molecular nano-dot patterns for RW-data storage in the optical near field. Journal of Microscopy. 229: 463-8. PMID 18331496 DOI: 10.1111/j.1365-2818.2008.01929.x |
0.025 |
|
2007 |
Björkdahl A, Heilig M, Palmstierna T, Hansebo G. Changes in the occurrences of coercive interventions and staff injuries on a psychiatric intensive care unit. Archives of Psychiatric Nursing. 21: 270-7. PMID 17904484 DOI: 10.1016/j.apnu.2007.06.007 |
0.023 |
|
2024 |
Guterstam J, Heilig M. [Not Available]. Lakartidningen. 121. PMID 38343319 |
0.023 |
|
2009 |
Gerken J, Heilig M, Jetter HC, Rexhausen S, Demarmels M, König WA, Reiterer H. Lessons learned from the design and evaluation of visual information-seeking systems International Journal On Digital Libraries. 10: 49-66. DOI: 10.1007/s00799-009-0052-6 |
0.022 |
|
1992 |
Korn M, Hennigs R, Heilig M. 105 HPLC determination of o-, m-, p-methylhippuric acids and hippuric acid in the urine of xylene and toluene exposed persons Fresenius' Journal of Analytical Chemistry. 343: 167-167. DOI: 10.1007/BF00332099 |
0.021 |
|
2015 |
Mallig N, Heilig M, Weiss C, Chlond B, Vortisch P. Modelling the weekly electricity demand caused by electric cars Future Generation Computer Systems. DOI: 10.1016/j.future.2016.01.014 |
0.019 |
|
2008 |
Heilig M, Demarmels M, König WA, Gerken J, Rexhausen S, Jetter HC, Reiterer H. MedioVis - Visual information seeking in digital libraries Proceedings of the Workshop On Advanced Visual Interfaces Avi. 490-491. DOI: 10.1145/1385569.1385671 |
0.019 |
|
1990 |
Heilig M, Franck EU. Phase Equilibria of Multicomponent Fluid Systems to High Pressures and Temperatures Berichte Der Bunsengesellschaft FüR Physikalische Chemie. 94: 27-35. DOI: 10.1002/BBPC.19900940107 |
0.019 |
|
2009 |
Heilig M, Mishra B, Marya M, Olson DL. Development of high interstitial stainless steels for down-hole drilling applications The Minerals, Metals and Materials Society - 3rd International Conference On Processing Materials For Properties 2008, Pmp Iii. 1: 393-399. |
0.019 |
|
2012 |
Kolew A, Heilig M, Schneider M, Sikora K, Münch D, Worgull M. Hot embossing of thermoplastic multilayered stacks Microsystem Technologies. 18: 1857-1861. DOI: 10.1007/s00542-012-1502-4 |
0.019 |
|
2014 |
Kolew A, Heilig M, Schneider M, Münch D, Ezzat R, Schneider N, Worgull M. Hot embossing of transparent high aspect ratio micro parts Microsystem Technologies. 20: 1967-1973. DOI: 10.1007/s00542-013-2021-7 |
0.018 |
|
1989 |
Heilig M, Franck EU. Calculation of Thermodynamic Properties of Binary Fluid Mixtures to High Temperatures and High Pressures Berichte Der Bunsengesellschaft FüR Physikalische Chemie. 93: 898-905. DOI: 10.1002/BBPC.19890930816 |
0.018 |
|
2007 |
Rath S, Heilig M, Port H, Wrachtrup J. Periodic organic nanodot patterns for optical memory. Nano Letters. 7: 3845-8. PMID 18020389 DOI: 10.1021/nl072598f |
0.016 |
|
2007 |
Jackson JE, Lasseigne-Jackson AN, Olson DL, Mishra B, Heilig MS, Collins JK. The effect of magnetic fields on corrosion in pipeline steel Proceedings of the International Conference On Offshore Mechanics and Arctic Engineering - Omae. 2: 383-391. DOI: 10.1115/OMAE2007-29560 |
0.015 |
|
2014 |
Heilig M, Bäuml D, Fürll M. [The relevance of the trace elements zinc and iron in the milk fever disease of cattle]. TieräRztliche Praxis. Ausgabe G, Grosstiere/Nutztiere. 42: 199-208. PMID 25119475 |
0.013 |
|
2011 |
Worgull M, Kolew A, Heilig M, Schneider M, Dinglreiter H. Replication of micro- and nano-structures | Abformen von Mikro- Und Nanostrukturen Galvanotechnik. 102: 928-936. |
0.013 |
|
1977 |
Heilig MC. Health awareness built into health service delivery in a community college. Journal of the American College Health Association. 26: 98-101. PMID 599228 |
0.012 |
|
2007 |
Gasch M, Schwarzer R, Heilig M. Neues Zylinderkopfdichtungskonzept für den Sechszylinder-Twin-Turbo-Ottomotor von BMW Mtz - Motortechnische Zeitschrift. 68: 38-41. DOI: 10.1007/BF03225443 |
0.012 |
|
2011 |
Heilig M, Schneider M, Dinglreiter H, Worgull M. Technology of microthermoforming of complex three-dimensional parts with multiscale features Microsystem Technologies. 17: 593-600. DOI: 10.1007/s00542-010-1203-9 |
0.011 |
|
2010 |
Worgull M, Schneider M, Heilig M, Kolew A, Dinglreiter H, Mohr J. Replication of optical components by hot embossing Proceedings of Spie - the International Society For Optical Engineering. 7716. DOI: 10.1117/12.859077 |
0.01 |
|
1999 |
Heilig M. [Re-establishing the medical culture in psychiatry!]. Lã¤Kartidningen. 96: 4427-8, 4431-3. PMID 10553322 |
0.01 |
|
1994 |
Heilig M. Antisense Technology Cns Drugs. 1: 405-409. DOI: 10.2165/00023210-199401060-00002 |
0.01 |
|
2017 |
Paulisch A, Heilig M, Knezic P. Dynamic Shaft Seal with High Vacuum Capability Mtz Worldwide. 78: 52-57. DOI: 10.1007/S38313-017-0037-6 |
0.01 |
|
2017 |
Paulisch A, Heilig M, Knezic P. Dynamische Kurbelwellendichtung mit hoher Vakuumtoleranz Mtz - Motortechnische Zeitschrift. 78: 62-67. DOI: 10.1007/S35146-017-0033-Z |
0.01 |
|
2014 |
Heilig MA. Daniel W. Hommer. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 3128. PMID 25381706 DOI: 10.1038/npp.2014.249 |
0.01 |
|
2012 |
Heilig M. Svaga argument mot en restriktiv narkotikapolitik Lakartidningen. 109. |
0.01 |
|
2011 |
Zander D, Heilig M, Hort N, Klaus G, B̈hrig-Polaczek A, Gröbner J, Schmid-Fetzer R. Influence of cerium on the formation of micro-galvanic corrosion elements of AZ91 Materials Science Forum. 690: 381-384. DOI: 10.4028/www.scientific.net/MSF.690.381 |
0.01 |
|
2011 |
Worgull M, Kolew A, Heilig M, Schneider M, Dinglreiter H, Rapp B. Hot embossing of high performance polymers Microsystem Technologies. 17: 585-592. DOI: 10.1007/s00542-010-1155-0 |
0.01 |
|
2011 |
Kolew A, Heilig M, Sikora K, Munch D, Worgull M. Multi-component hot embossing of micro- and nanosystems Dtip 2011 - Symposium On Design, Test, Integration and Packaging of Mems/Moems. 284-287. |
0.01 |
|
2010 |
Heilig M, Huber S, Demarmels M, Reiterer H. ScatterTouch: A multi touch rubber sheet scatter plot visualization for co-located data exploration Acm International Conference On Interactive Tabletops and Surfaces, Its 2010. 263-264. DOI: 10.1145/1936652.1936707 |
0.01 |
|
2010 |
Heilig M, Giselbrecht S, Guber A, Worgull M. Microthermoforming of nanostructured polymer films: A new bonding method for the integration of nanostructures in 3-dimensional cavities Microsystem Technologies. 16: 1221-1231. DOI: 10.1007/s00542-010-1072-2 |
0.01 |
|
2010 |
Röhrig VM, Heilig M, Schneider M, Kolew A, Kaiser K, Guttmann M, Worgull M. Universal fixation of shim mold inserts for micro and nano replication based on polymer films | Universelle Fixierung von Shim-Formeinsätzen für die Mikro- und Nanoreplikation auf Basis von Polymerfolien Galvanotechnik. 101: 1646-1653. |
0.01 |
|
2010 |
Heilig M, Mishra B, Marya M, Olson DL. Casting practice for high-carbon nitrogen-alloyed chromium-manganese austenitic stainless steels Tms Annual Meeting. 1: 695-702. |
0.01 |
|
2010 |
Zander D, Heilig M, Hort N, Klaus G, Buehrig-Polaczek A, Grbbner J, Schmid-Fetzer R. Microstructure and corrosion of AZ91 with small amounts of cerium Magnesium Technology. 187-191. |
0.01 |
|
2009 |
Heilig M, Giselbrecht S, Guber A, Worgull M. Micro thermoforming of nanostructured polymer films: A new bonding method for the integration of nanostructures in 3-dimensional cavities Dtip of Mems and Moems - Symposium On Design, Test, Integration and Packaging of Mems/Moems. 132-135. |
0.01 |
|
2007 |
Gasch M, Schwarzer R, Heilig M. New cylinder head gasket concept for the BMW six cylinder twin turbo gasoline engine Mtz Worldwide. 68: 14-15. DOI: 10.1007/BF03227970 |
0.01 |
|
1998 |
Cierocki K, Schmitt K, Heilig M, Hilgert C. Neuartige Einlagen-Stahl-Zylinderkopfdichtung Mtz - Motortechnische Zeitschrift. 59: 298-302. DOI: 10.1007/BF03226452 |
0.01 |
|
1990 |
Wu G, Heilig M, Lentz H, Franck EU. High Pressure Phase Equilibria of the Water-Argon System Berichte Der Bunsengesellschaft FüR Physikalische Chemie. 94: 24-27. DOI: 10.1002/BBPC.19900940106 |
0.01 |
|
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