| Year |
Citation |
Score |
| 2021 |
Liu HY, Gale JR, Reynolds IJ, Weiss JH, Aizenman E. The Multifaceted Roles of Zinc in Neuronal Mitochondrial Dysfunction. Biomedicines. 9. PMID 33946782 DOI: 10.3390/biomedicines9050489 |
0.743 |
|
| 2020 |
Aizenman E, Loring RH, Reynolds IJ, Rosenberg PA. The Redox Biology of Excitotoxic Processes: The NMDA Receptor, TOPA Quinone, and the Oxidative Liberation of Intracellular Zinc. Frontiers in Neuroscience. 14: 778. PMID 32792905 DOI: 10.3389/Fnins.2020.00778 |
0.727 |
|
| 2017 |
Divakaruni AS, Wallace M, Buren C, Martyniuk K, Andreyev AY, Li E, Fields JA, Cordes T, Reynolds IJ, Bloodgood BL, Raymond LA, Metallo CM, Murphy AN. Inhibition of the mitochondrial pyruvate carrier protects from excitotoxic neuronal death. The Journal of Cell Biology. PMID 28254829 DOI: 10.1083/Jcb.201612067 |
0.496 |
|
| 2012 |
Le Poul E, Boléa C, Girard F, Poli S, Charvin D, Campo B, Bortoli J, Bessif A, Luo B, Koser AJ, Hodge LM, Smith KM, DiLella AG, Liverton N, Hess F, ... Reynolds IJ, et al. A potent and selective metabotropic glutamate receptor 4 positive allosteric modulator improves movement in rodent models of Parkinson's disease. The Journal of Pharmacology and Experimental Therapeutics. 343: 167-77. PMID 22787118 DOI: 10.1124/Jpet.112.196063 |
0.324 |
|
| 2012 |
Nikonova EV, Xiong Y, Tanis KQ, Dawson VL, Vogel RL, Finney EM, Stone DJ, Reynolds IJ, Kern JT, Dawson TM. Transcriptional responses to loss or gain of function of the leucine-rich repeat kinase 2 (LRRK2) gene uncover biological processes modulated by LRRK2 activity. Human Molecular Genetics. 21: 163-74. PMID 21972245 DOI: 10.1093/Hmg/Ddr451 |
0.417 |
|
| 2011 |
Chen HK, Ji ZS, Dodson SE, Miranda RD, Rosenblum CI, Reynolds IJ, Freedman SB, Weisgraber KH, Huang Y, Mahley RW. Apolipoprotein E4 domain interaction mediates detrimental effects on mitochondria and is a potential therapeutic target for Alzheimer disease. The Journal of Biological Chemistry. 286: 5215-21. PMID 21118811 DOI: 10.1074/Jbc.M110.151084 |
0.387 |
|
| 2010 |
Rintoul GL, Reynolds IJ. Mitochondrial trafficking and morphology in neuronal injury. Biochimica Et Biophysica Acta. 1802: 143-50. PMID 19747973 DOI: 10.1016/J.Bbadis.2009.09.005 |
0.44 |
|
| 2009 |
Chen H, Ji Z, Miranda RD, McGuire J, Wong J, Vongs A, Rosenblum CI, Reynolds IJ, Freedman SB, Weisgraber KH, Huang Y, Seabrook GR, Mahley RW. Apolipoprotein E4-induced mitochondrial dysfunction depends on its structure and can be rescued by a structure corrector Alzheimers & Dementia. 5: 307. DOI: 10.1016/J.Jalz.2009.04.468 |
0.311 |
|
| 2008 |
Dineley KE, Devinney MJ, Zeak JA, Rintoul GL, Reynolds IJ. Glutamate mobilizes [Zn2+] through Ca2+ -dependent reactive oxygen species accumulation. Journal of Neurochemistry. 106: 2184-93. PMID 18624907 DOI: 10.1111/J.1471-4159.2008.05536.X |
0.812 |
|
| 2008 |
Malin SA, Davis BM, Koerber HR, Reynolds IJ, Albers KM, Molliver DC. Thermal nociception and TRPV1 function are attenuated in mice lacking the nucleotide receptor P2Y2. Pain. 138: 484-96. PMID 18343036 DOI: 10.1016/J.Pain.2008.01.026 |
0.318 |
|
| 2008 |
Dineley KE, Richards LL, Votyakova TV, Reynolds IJ. Zinc causes loss of membrane potential and alters production of reactive oxygen species in isolated brain mitochondria Journal of Neurochemistry. 81: 101-105. DOI: 10.1046/J.1471-4159.81.S1.40_16.X |
0.787 |
|
| 2007 |
Gusdon AM, Votyakova TV, Reynolds IJ, Mathews CE. Nuclear and mitochondrial interaction involving mt-Nd2 leads to increased mitochondrial reactive oxygen species production. The Journal of Biological Chemistry. 282: 5171-9. PMID 17189252 DOI: 10.1074/Jbc.M609367200 |
0.357 |
|
| 2007 |
Vergun O, Dineley KE, Reynolds IJ. Ion transport and energy metabolism Handbook of Neurochemistry and Molecular Neurobiology: Brain Energetics. Integration of Molecular and Cellular Processes. 429-465. DOI: 10.1007/978-0-387-30411-3_16 |
0.662 |
|
| 2006 |
Beal MF, Bossy-Wetzel E, Finkbeiner S, Fiskum G, Giasson B, Johnson C, Khachaturian ZS, Lee VM, Nicholls D, Reddy H, Reynolds I, Teplow DB, Thal LJ, Trojanowski JQ, Walsh DM, et al. Common threads in neurodegenerative disorders of aging. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 2: 322-6. PMID 19595906 DOI: 10.1016/J.Jalz.2006.08.008 |
0.517 |
|
| 2006 |
Chang DT, Reynolds IJ. Mitochondrial trafficking and morphology in healthy and injured neurons. Progress in Neurobiology. 80: 241-68. PMID 17188795 DOI: 10.1016/J.Pneurobio.2006.09.003 |
0.684 |
|
| 2006 |
Chang DT, Honick AS, Reynolds IJ. Mitochondrial trafficking to synapses in cultured primary cortical neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 7035-45. PMID 16807333 DOI: 10.1523/Jneurosci.1012-06.2006 |
0.63 |
|
| 2006 |
Chang DT, Reynolds IJ. Differences in mitochondrial movement and morphology in young and mature primary cortical neurons in culture. Neuroscience. 141: 727-36. PMID 16797853 DOI: 10.1016/J.Neuroscience.2006.01.034 |
0.688 |
|
| 2006 |
Rintoul GL, Bennett VJ, Papaconstandinou NA, Reynolds IJ. Nitric oxide inhibits mitochondrial movement in forebrain neurons associated with disruption of mitochondrial membrane potential. Journal of Neurochemistry. 97: 800-6. PMID 16573650 DOI: 10.1111/J.1471-4159.2006.03788.X |
0.456 |
|
| 2006 |
Chang DT, Rintoul GL, Pandipati S, Reynolds IJ. Mutant huntingtin aggregates impair mitochondrial movement and trafficking in cortical neurons. Neurobiology of Disease. 22: 388-400. PMID 16473015 DOI: 10.1016/J.Nbd.2005.12.007 |
0.646 |
|
| 2005 |
Malaiyandi LM, Honick AS, Rintoul GL, Wang QJ, Reynolds IJ. Zn2+ inhibits mitochondrial movement in neurons by phosphatidylinositol 3-kinase activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9507-14. PMID 16221861 DOI: 10.1523/Jneurosci.0868-05.2005 |
0.805 |
|
| 2005 |
Vergun O, Reynolds IJ. Distinct characteristics of Ca(2+)-induced depolarization of isolated brain and liver mitochondria. Biochimica Et Biophysica Acta. 1709: 127-37. PMID 16112074 DOI: 10.1016/J.Bbabio.2005.07.006 |
0.413 |
|
| 2005 |
Dineley KE, Richards LL, Votyakova TV, Reynolds IJ. Zinc causes loss of membrane potential and elevates reactive oxygen species in rat brain mitochondria. Mitochondrion. 5: 55-65. PMID 16060292 DOI: 10.1016/J.Mito.2004.11.001 |
0.772 |
|
| 2005 |
Kress GJ, Reynolds IJ. Dopaminergic neurotoxins require excitotoxic stimulation in organotypic cultures. Neurobiology of Disease. 20: 639-45. PMID 15996475 DOI: 10.1016/J.Nbd.2005.04.019 |
0.415 |
|
| 2005 |
Malaiyandi LM, Vergun O, Dineley KE, Reynolds IJ. Direct visualization of mitochondrial zinc accumulation reveals uniporter-dependent and -independent transport mechanisms. Journal of Neurochemistry. 93: 1242-50. PMID 15934944 DOI: 10.1111/J.1471-4159.2005.03116.X |
0.801 |
|
| 2005 |
Votyakova TV, Reynolds IJ. Ca2+-induced permeabilization promotes free radical release from rat brain mitochondria with partially inhibited complex I. Journal of Neurochemistry. 93: 526-37. PMID 15836612 DOI: 10.1111/J.1471-4159.2005.03042.X |
0.427 |
|
| 2005 |
Devinney MJ, Reynolds IJ, Dineley KE. Simultaneous detection of intracellular free calcium and zinc using fura-2FF and FluoZin-3. Cell Calcium. 37: 225-32. PMID 15670869 DOI: 10.1016/J.Ceca.2004.10.003 |
0.78 |
|
| 2004 |
Votyakova TV, Reynolds IJ. Detection of hydrogen peroxide with Amplex Red: interference by NADH and reduced glutathione auto-oxidation. Archives of Biochemistry and Biophysics. 431: 138-44. PMID 15464736 DOI: 10.1016/J.Abb.2004.07.025 |
0.318 |
|
| 2004 |
Reynolds IJ, Rintoul GL. Mitochondrial stop and go: signals that regulate organelle movement. Science's Stke : Signal Transduction Knowledge Environment. 2004: PE46. PMID 15383673 DOI: 10.1126/Stke.2512004Pe46 |
0.392 |
|
| 2004 |
Reynolds IJ, Malaiyandi LM, Coash M, Rintoul GL. Mitochondrial trafficking in neurons: a key variable in neurodegeneration? Journal of Bioenergetics and Biomembranes. 36: 283-6. PMID 15377858 DOI: 10.1023/B:Jobb.0000041754.78313.C2 |
0.812 |
|
| 2004 |
Vergun O, Reynolds IJ. Fluctuations in mitochondrial membrane potential in single isolated brain mitochondria: modulation by adenine nucleotides and Ca2+. Biophysical Journal. 87: 3585-93. PMID 15315954 DOI: 10.1529/Biophysj.104.042671 |
0.445 |
|
| 2004 |
Reynolds IJ. Fluorescence detection of redox-sensitive metals in neuronal culture: focus on iron and zinc. Annals of the New York Academy of Sciences. 1012: 27-36. PMID 15105253 DOI: 10.1196/Annals.1306.003 |
0.4 |
|
| 2004 |
Glading A, Bodnar RJ, Reynolds IJ, Shiraha H, Satish L, Potter DA, Blair HC, Wells A. Epidermal growth factor activates m-calpain (calpain II), at least in part, by extracellular signal-regulated kinase-mediated phosphorylation. Molecular and Cellular Biology. 24: 2499-512. PMID 14993287 DOI: 10.1128/Mcb.24.6.2499-2512.2004 |
0.301 |
|
| 2004 |
Malaiyandi LM, Dineley KE, Reynolds IJ. Divergent consequences arise from metallothionein overexpression in astrocytes: zinc buffering and oxidant-induced zinc release. Glia. 45: 346-53. PMID 14966866 DOI: 10.1002/Glia.10332 |
0.788 |
|
| 2004 |
Kang HJ, Choi YS, Hong SB, Kim KW, Woo RS, Won SJ, Kim EJ, Jeon HK, Jo SY, Kim TK, Bachoo R, Reynolds IJ, Gwag BJ, Lee HW. Ectopic expression of the catalytic subunit of telomerase protects against brain injury resulting from ischemia and NMDA-induced neurotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 1280-7. PMID 14960598 DOI: 10.1523/Jneurosci.4082-03.2004 |
0.502 |
|
| 2003 |
Vergun O, Votyakova TV, Reynolds IJ. Spontaneous changes in mitochondrial membrane potential in single isolated brain mitochondria. Biophysical Journal. 85: 3358-66. PMID 14581237 DOI: 10.1016/S0006-3495(03)74755-9 |
0.424 |
|
| 2003 |
Vergun O, Han YY, Reynolds IJ. Glucose deprivation produces a prolonged increase in sensitivity to glutamate in cultured rat cortical neurons. Experimental Neurology. 183: 682-94. PMID 14552910 DOI: 10.1016/S0014-4886(03)00243-7 |
0.55 |
|
| 2003 |
Rintoul GL, Filiano AJ, Brocard JB, Kress GJ, Reynolds IJ. Glutamate decreases mitochondrial size and movement in primary forebrain neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7881-8. PMID 12944518 DOI: 10.1523/Jneurosci.23-21-07881.2003 |
0.75 |
|
| 2003 |
Brocard JB, Rintoul GL, Reynolds IJ. New perspectives on mitochondrial morphology in cell function. Biology of the Cell / Under the Auspices of the European Cell Biology Organization. 95: 239-42. PMID 12941521 DOI: 10.1016/S0248-4900(03)00062-5 |
0.335 |
|
| 2003 |
Dineley KE, Votyakova TV, Reynolds IJ. Zinc inhibition of cellular energy production: implications for mitochondria and neurodegeneration. Journal of Neurochemistry. 85: 563-70. PMID 12694382 DOI: 10.1046/J.1471-4159.2003.01678.X |
0.768 |
|
| 2003 |
Reynolds IJ, Filiano AJ, Malaiyandi LM, Rintoul GL, Votyakova TV. Interaction between mitochondria and oxidative stress in neuronal injury Journal of Neurochemistry. 85: 3-3. DOI: 10.1046/J.1471-4159.85.S2.3_1.X |
0.816 |
|
| 2002 |
Dineley KE, Brocard JB, Reynolds IJ. Elevated intracellular zinc and altered proton homeostasis in forebrain neurons. Neuroscience. 114: 439-49. PMID 12204213 DOI: 10.1016/S0306-4522(02)00294-4 |
0.774 |
|
| 2002 |
Dineley KE, Malaiyandi LM, Reynolds IJ. A reevaluation of neuronal zinc measurements: artifacts associated with high intracellular dye concentration. Molecular Pharmacology. 62: 618-27. PMID 12181438 DOI: 10.1124/Mol.62.3.618 |
0.792 |
|
| 2002 |
Tang ZL, Wasserloos KJ, Liu X, Stitt MS, Reynolds IJ, Pitt BR, St Croix CM. Nitric oxide decreases the sensitivity of pulmonary endothelial cells to LPS-induced apoptosis in a zinc-dependent fashion. Molecular and Cellular Biochemistry. 234: 211-7. PMID 12162436 DOI: 10.1007/978-1-4615-1087-1_24 |
0.344 |
|
| 2002 |
Kress GJ, Dineley KE, Reynolds IJ. The relationship between intracellular free iron and cell injury in cultured neurons, astrocytes, and oligodendrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 5848-55. PMID 12122047 DOI: 10.1523/Jneurosci.22-14-05848.2002 |
0.714 |
|
| 2002 |
St Croix CM, Wasserloos KJ, Dineley KE, Reynolds IJ, Levitan ES, Pitt BR. Nitric oxide-induced changes in intracellular zinc homeostasis are mediated by metallothionein/thionein. American Journal of Physiology. Lung Cellular and Molecular Physiology. 282: L185-92. PMID 11792622 DOI: 10.1152/Ajplung.00267.2001 |
0.743 |
|
| 2001 |
Reynolds IJ. [3H](+)MK801 radioligand binding assay at the N-methyl-D-aspartate receptor. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. Unit 1.20. PMID 22293962 DOI: 10.1002/0471141755.Ph0120S11 |
0.351 |
|
| 2001 |
Reynolds IJ. Measurement of cation movement in primary cultures using fluorescent dyes. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit7.11. PMID 18428522 DOI: 10.1002/0471142301.Ns0711S04 |
0.374 |
|
| 2001 |
Votyakova TV, Reynolds IJ. DeltaPsi(m)-Dependent and -independent production of reactive oxygen species by rat brain mitochondria. Journal of Neurochemistry. 79: 266-77. PMID 11677254 DOI: 10.1046/J.1471-4159.2001.00548.X |
0.415 |
|
| 2001 |
Birder LA, Kanai AJ, de Groat WC, Kiss S, Nealen ML, Burke NE, Dineley KE, Watkins S, Reynolds IJ, Caterina MJ. Vanilloid receptor expression suggests a sensory role for urinary bladder epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 98: 13396-401. PMID 11606761 DOI: 10.1073/Pnas.231243698 |
0.714 |
|
| 2001 |
Buckman JF, Reynolds IJ. Spontaneous changes in mitochondrial membrane potential in cultured neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 5054-65. PMID 11438581 DOI: 10.1523/Jneurosci.21-14-05054.2001 |
0.451 |
|
| 2001 |
Brocard JB, Tassetto M, Reynolds IJ. Quantitative evaluation of mitochondrial calcium content in rat cortical neurones following a glutamate stimulus. The Journal of Physiology. 531: 793-805. PMID 11251059 DOI: 10.1111/J.1469-7793.2001.0793H.X |
0.511 |
|
| 2001 |
Buckman JF, Hernández H, Kress GJ, Votyakova TV, Pal S, Reynolds IJ. MitoTracker labeling in primary neuronal and astrocytic cultures: influence of mitochondrial membrane potential and oxidants. Journal of Neuroscience Methods. 104: 165-76. PMID 11164242 DOI: 10.1016/S0165-0270(00)00340-X |
0.468 |
|
| 2000 |
Scanlon JM, Brocard JB, Stout AK, Reynolds IJ. Pharmacological investigation of mitochondrial ca(2+) transport in central neurons: studies with CGP-37157, an inhibitor of the mitochondrial Na(+)-Ca(2+) exchanger. Cell Calcium. 28: 317-27. PMID 11115371 DOI: 10.1054/Ceca.2000.0171 |
0.787 |
|
| 2000 |
Aizenman E, Stout AK, Hartnett KA, Dineley KE, McLaughlin B, Reynolds IJ. Induction of neuronal apoptosis by thiol oxidation: putative role of intracellular zinc release. Journal of Neurochemistry. 75: 1878-88. PMID 11032877 DOI: 10.1046/J.1471-4159.2000.0751878.X |
0.824 |
|
| 2000 |
Dineley KE, Scanlon JM, Kress GJ, Stout AK, Reynolds IJ. Astrocytes are more resistant than neurons to the cytotoxic effects of increased [Zn(2+)](i). Neurobiology of Disease. 7: 310-20. PMID 10964603 DOI: 10.1006/Nbdi.2000.0303 |
0.815 |
|
| 2000 |
Hoyt KR, McLaughlin BA, Higgins DS, Reynolds IJ. Inhibition of glutamate-induced mitochondrial depolarization by tamoxifen in cultured neurons. The Journal of Pharmacology and Experimental Therapeutics. 293: 480-6. PMID 10773018 |
0.838 |
|
| 2000 |
Stanciu M, Wang Y, Kentor R, Burke N, Watkins S, Kress G, Reynolds I, Klann E, Angiolieri MR, Johnson JW, DeFranco DB. Persistent activation of ERK contributes to glutamate-induced oxidative toxicity in a neuronal cell line and primary cortical neuron cultures. The Journal of Biological Chemistry. 275: 12200-6. PMID 10766856 DOI: 10.1074/Jbc.275.16.12200 |
0.466 |
|
| 2000 |
Cheng C, Reynolds IJ. Subcellular localization of glutamate-stimulated intracellular magnesium concentration changes in cultured rat forebrain neurons using confocal microscopy. Neuroscience. 95: 973-9. PMID 10682704 DOI: 10.1016/S0306-4522(99)00471-6 |
0.506 |
|
| 1999 |
Reynolds IJ. Mitochondrial membrane potential and the permeability transition in excitotoxicity. Annals of the New York Academy of Sciences. 893: 33-41. PMID 10672228 DOI: 10.1111/J.1749-6632.1999.Tb07816.X |
0.52 |
|
| 1999 |
Cheng C, Fass DM, Reynolds IJ. Emergence of excitotoxicity in cultured forebrain neurons coincides with larger glutamate-stimulated [Ca(2+)](i) increases and NMDA receptor mRNA levels. Brain Research. 849: 97-108. PMID 10592291 DOI: 10.1016/S0006-8993(99)01995-2 |
0.489 |
|
| 1999 |
Reynolds IJ, Sharma TA. The use of ligand binding in assays of NMDA receptor function. Methods in Molecular Biology (Clifton, N.J.). 128: 93-102. PMID 10320975 DOI: 10.1385/1-59259-683-5:93 |
0.315 |
|
| 1999 |
Stout AK, Reynolds IJ. High-affinity calcium indicators underestimate increases in intracellular calcium concentrations associated with excitotoxic glutamate stimulations. Neuroscience. 89: 91-100. PMID 10051219 DOI: 10.1016/S0306-4522(98)00441-2 |
0.446 |
|
| 1998 |
Stout AK, Raphael HM, Kanterewicz BI, Klann E, Reynolds IJ. Glutamate-induced neuron death requires mitochondrial calcium uptake. Nature Neuroscience. 1: 366-73. PMID 10196525 DOI: 10.1038/1577 |
0.507 |
|
| 1998 |
Sharma TA, Carr AJ, Davis RS, Reynolds IJ, Hamilton AD. Aromatic analogs of arcaine inhibit MK-801 binding to the NMDA receptor. Bioorganic & Medicinal Chemistry Letters. 8: 3459-64. PMID 9934452 DOI: 10.1016/S0960-894X(98)00631-3 |
0.353 |
|
| 1998 |
Reynolds IJ. Intracellular calcium and magnesium: critical determinants of excitotoxicity? Progress in Brain Research. 116: 225-43. PMID 9932380 DOI: 10.1016/S0079-6123(08)60440-9 |
0.439 |
|
| 1998 |
Cheng C, Reynolds IJ. Calcium-sensitive fluorescent dyes can report increases in intracellular free zinc concentration in cultured forebrain neurons. Journal of Neurochemistry. 71: 2401-10. PMID 9832138 DOI: 10.1046/J.1471-4159.1998.71062401.X |
0.496 |
|
| 1998 |
Scanlon JM, Reynolds IJ. Effects of oxidants and glutamate receptor activation on mitochondrial membrane potential in rat forebrain neurons. Journal of Neurochemistry. 71: 2392-400. PMID 9832137 DOI: 10.1046/J.1471-4159.1998.71062392.X |
0.8 |
|
| 1998 |
Sharma TA, Reynolds IJ. Complex polyamine effects on [3H]MDL 105,519 binding to the NMDA receptor glycine site. Neurochemistry International. 33: 155-9. PMID 9761459 DOI: 10.1016/S0197-0186(98)00015-1 |
0.339 |
|
| 1998 |
Hoyt KR, Reynolds IJ. Alkalinization prolongs recovery from glutamate-induced increases in intracellular Ca2+ concentration by enhancing Ca2+ efflux through the mitochondrial Na+/Ca2+ exchanger in cultured rat forebrain neurons. Journal of Neurochemistry. 71: 1051-8. PMID 9721729 DOI: 10.1046/J.1471-4159.1998.71031051.X |
0.752 |
|
| 1998 |
Hoyt KR, Stout AK, Cardman JM, Reynolds IJ. The role of intracellular Na+ and mitochondria in buffering of kainate-induced intracellular free Ca2+ changes in rat forebrain neurones. The Journal of Physiology. 509: 103-16. PMID 9547385 DOI: 10.1111/J.1469-7793.1998.103Bo.X |
0.769 |
|
| 1998 |
Hoyt KR, Arden SR, Aizenman E, Reynolds IJ. Reverse Na+/Ca2+ exchange contributes to glutamate-induced intracellular Ca2+ concentration increases in cultured rat forebrain neurons. Molecular Pharmacology. 53: 742-9. PMID 9547366 DOI: 10.1124/Mol.53.4.742 |
0.818 |
|
| 1997 |
Hoyt KR, Sharma TA, Reynolds IJ. Trifluoperazine and dibucaine-induced inhibition of glutamate-induced mitochondrial depolarization in rat cultured forebrain neurones. British Journal of Pharmacology. 122: 803-8. PMID 9384493 DOI: 10.1038/Sj.Bjp.0701442 |
0.791 |
|
| 1997 |
Scanlon JM, Aizenman E, Reynolds IJ. Effects of pyrroloquinoline quinone on glutamate-induced production of reactive oxygen species in neurons. European Journal of Pharmacology. 326: 67-74. PMID 9178657 DOI: 10.1016/S0014-2999(97)00137-4 |
0.821 |
|
| 1997 |
Hartnett KA, Stout AK, Rajdev S, Rosenberg PA, Reynolds IJ, Aizenman E. NMDA receptor-mediated neurotoxicity: a paradoxical requirement for extracellular Mg2+ in Na+/Ca2+-free solutions in rat cortical neurons in vitro. Journal of Neurochemistry. 68: 1836-45. PMID 9109508 DOI: 10.1046/J.1471-4159.1997.68051836.X |
0.774 |
|
| 1997 |
Hoyt KR, Reynolds IJ, Hastings TG. Mechanisms of dopamine-induced cell death in cultured rat forebrain neurons: interactions with and differences from glutamate-induced cell death. Experimental Neurology. 143: 269-81. PMID 9056389 DOI: 10.1006/Exnr.1996.6374 |
0.753 |
|
| 1997 |
Hoyt KR, Gallagher AJ, Hastings TG, Reynolds IJ. Characterization of hydrogen peroxide toxicity in cultured rat forebrain neurons. Neurochemical Research. 22: 333-40. PMID 9051670 DOI: 10.1023/A:1022403224901 |
0.772 |
|
| 1997 |
White RJ, Reynolds IJ. Mitochondria accumulate Ca2+ following intense glutamate stimulation of cultured rat forebrain neurones. The Journal of Physiology. 498: 31-47. PMID 9023766 DOI: 10.1113/Jphysiol.1997.Sp021839 |
0.509 |
|
| 1996 |
Hoyt KR, Reynolds IJ. Localization of D1 dopamine receptors on live cultured striatal neurons by quantitative fluorescence microscopy. Brain Research. 731: 21-30. PMID 8883850 DOI: 10.1016/0006-8993(96)00436-2 |
0.73 |
|
| 1996 |
White RJ, Reynolds IJ. Mitochondrial depolarization in glutamate-stimulated neurons: an early signal specific to excitotoxin exposure. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 5688-97. PMID 8795624 |
0.433 |
|
| 1996 |
Stout AK, Li-Smerin Y, Johnson JW, Reynolds IJ. Mechanisms of glutamate-stimulated Mg2+ influx and subsequent Mg2+ efflux in rat forebrain neurones in culture. The Journal of Physiology. 492: 641-57. PMID 8734978 DOI: 10.1113/Jphysiol.1996.Sp021334 |
0.402 |
|
| 1995 |
White RJ, Reynolds IJ. Mitochondria and Na+/Ca2+ exchange buffer glutamate-induced calcium loads in cultured cortical neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 1318-28. PMID 7869100 DOI: 10.1523/Jneurosci.15-02-01318.1995 |
0.485 |
|
| 1995 |
Reynolds IJ, Hastings TG. Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 3318-27. PMID 7751912 DOI: 10.1523/Jneurosci.15-05-03318.1995 |
0.506 |
|
| 1995 |
Hoyt KR, Rajdev S, Fattman CL, Reynolds IJ. Cyclothiazide modulates AMPA receptor-mediated increases in intracellular free Ca2+ and Mg2+ in cultured neurons from rat brain. Journal of Neurochemistry. 64: 2049-56. PMID 7536804 DOI: 10.1046/J.1471-4159.1995.64052049.X |
0.774 |
|
| 1995 |
Rajdev S, Reynolds IJ. Calcium influx but not pH or ATP level mediates glutamate-induced changes in intracellular magnesium in cortical neurons. Journal of Neurophysiology. 74: 942-9. PMID 7500163 DOI: 10.1152/Jn.1995.74.3.942 |
0.506 |
|
| 1995 |
Reynolds I, Hastings T. Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation The Journal of Neuroscience. 15: 3318-3327. DOI: 10.1523/JNEUROSCI.15-05-03318.1995 |
0.341 |
|
| 1994 |
Weng W, Reynolds IJ, Jani JP, Blaskovich M, Sebti SM, Davies P, Pitt BR. Desensitization of 5HT2 receptors by protein kinase C activation in distal pulmonary vascular smooth muscle cells in culture. Microcirculation (New York, N.Y. : 1994). 1: 129-35. PMID 8790584 DOI: 10.3109/10739689409148268 |
0.321 |
|
| 1994 |
Reynolds IJ. [3H]CGP 39653 binding to the agonist site of the N-methyl-D-aspartate receptor is modulated by Mg2+ and polyamines independently of the arcaine-sensitive polyamine site. Journal of Neurochemistry. 62: 54-62. PMID 7903355 DOI: 10.1046/J.1471-4159.1994.62010054.X |
0.362 |
|
| 1994 |
Rajdev S, Reynolds IJ. Glutamate-induced intracellular calcium changes and neurotoxicity in cortical neurons in vitro: effect of chemical ischemia. Neuroscience. 62: 667-79. PMID 7870298 DOI: 10.1016/0306-4522(94)90468-5 |
0.473 |
|
| 1993 |
Rajdev S, Reynolds IJ. Effects of pH on the actions of dizocilpine at the N-methyl-D-aspartate receptor complex. British Journal of Pharmacology. 109: 107-12. PMID 8495234 DOI: 10.1111/J.1476-5381.1993.Tb13538.X |
0.425 |
|
| 1993 |
Reynolds IJ, Zeleski DM, Rothermund KD, Hartnett KA, Tidwell R, Aizenman E. Studies on the effects of several pentamidine analogues on the NMDA receptor. European Journal of Pharmacology. 244: 175-9. PMID 8432312 DOI: 10.1016/0922-4106(93)90023-3 |
0.738 |
|
| 1993 |
Brocard JB, Rajdev S, Reynolds IJ. Glutamate-induced increases in intracellular free Mg2+ in cultured cortical neurons. Neuron. 11: 751-7. PMID 8104432 DOI: 10.1016/0896-6273(93)90084-5 |
0.472 |
|
| 1993 |
Rajdev S, Reynolds IJ. Calcium green-5N, a novel fluorescent probe for monitoring high intracellular free Ca2+ concentrations associated with glutamate excitotoxicity in cultured rat brain neurons. Neuroscience Letters. 162: 149-52. PMID 7907171 DOI: 10.1016/0304-3940(93)90582-6 |
0.478 |
|
| 1993 |
Reynolds IJ, Rothermund KD, Rajdev S. Interaction of rigid polyamine analogues with the NMDA receptor complex from rat brain Bioorganic and Medicinal Chemistry Letters. 3: 85-90. DOI: 10.1016/S0960-894X(00)80097-9 |
0.355 |
|
| 1992 |
Aizenman E, Reynolds IJ. Modulation of NMDA excitotoxicity by redox reagents. Annals of the New York Academy of Sciences. 648: 125-31. PMID 1637042 DOI: 10.1111/J.1749-6632.1992.Tb24530.X |
0.711 |
|
| 1992 |
Rajdev S, Reynolds IJ. Effects of monovalent and divalent cations on 3-(+)[125I]iododizocilpine binding to the N-methyl-D-aspartate receptor of rat brain membranes. Journal of Neurochemistry. 58: 1469-76. PMID 1532196 DOI: 10.1111/J.1471-4159.1992.Tb11366.X |
0.412 |
|
| 1992 |
Reynolds IJ, Aizenman E. Pentamidine is an N-methyl-D-aspartate receptor antagonist and is neuroprotective in vitro. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 970-5. PMID 1532027 DOI: 10.1523/Jneurosci.12-03-00970.1992 |
0.759 |
|
| 1992 |
Hoyt KR, Tang LH, Aizenman E, Reynolds IJ. Nitric oxide modulates NMDA-induced increases in intracellular Ca2+ in cultured rat forebrain neurons. Brain Research. 592: 310-6. PMID 1450920 DOI: 10.1016/0006-8993(92)91690-G |
0.829 |
|
| 1992 |
Reynolds IJ, Rothermund K, Rajdev S, Fauq AH, Kozikowski AP. [125I]thienylphencyclidine, a novel ligand for the NMDA receptor. European Journal of Pharmacology. 226: 53-8. PMID 1356810 DOI: 10.1016/0922-4106(92)90082-7 |
0.332 |
|
| 1992 |
Chen C, Kozikowski AP, Wood PL, Reynolds IJ, Ball RG, Pang YP. Synthesis and biological activity of 8a-phenyldecahydroquinolines as probes of PCP's binding conformation. A new PCP-like compound with increased in vivo potency. Journal of Medicinal Chemistry. 35: 1634-8. PMID 1315871 DOI: 10.1021/Jm00087A020 |
0.308 |
|
| 1991 |
Gilbert KR, Aizenman E, Reynolds IJ. Oxidized glutathione modulates N-methyl-D-aspartate- and depolarization-induced increases in intracellular Ca2+ in cultured rat forebrain neurons. Neuroscience Letters. 133: 11-4. PMID 1838798 DOI: 10.1016/0304-3940(91)90045-U |
0.771 |
|
| 1991 |
Aizenman E, Tang LH, Reynolds IJ. Effects of nicotinic agonists on the NMDA receptor. Brain Research. 551: 355-7. PMID 1833030 DOI: 10.1016/0006-8993(91)90958-X |
0.708 |
|
| 1991 |
Reynolds IJ. The spider toxin, argiotoxin636, binds to a Mg2+ site on the N-methyl-D-aspartate receptor complex. British Journal of Pharmacology. 103: 1373-6. PMID 1832066 DOI: 10.1111/J.1476-5381.1991.Tb09796.X |
0.392 |
|
| 1991 |
Reynolds IJ, Palmer AM. Regional variations in [3H]MK801 binding to rat brain N-methyl-D-aspartate receptors. Journal of Neurochemistry. 56: 1731-40. PMID 1826521 DOI: 10.1111/J.1471-4159.1991.Tb02074.X |
0.374 |
|
| 1991 |
Reynolds IJ, Baron BM, Edwards ML. 1,10-bis(guanidino)decane inhibits N-methyl-D-aspartate responses in vitro and in vivo. The Journal of Pharmacology and Experimental Therapeutics. 259: 626-32. PMID 1658306 |
0.347 |
|
| 1990 |
Kozikowski AP, Tückmantel W, Reynolds IJ, Wroblewski JT. Synthesis and bioactivity of a new class of rigid glutamate analogues. Modulators of the N-methyl-D-aspartate receptor. Journal of Medicinal Chemistry. 33: 1561-71. PMID 2160533 DOI: 10.1021/Jm00168A007 |
0.427 |
|
| 1990 |
Reynolds IJ. Arcaine is a competitive antagonist of the polyamine site on the NMDA receptor. European Journal of Pharmacology. 177: 215-6. PMID 2155812 DOI: 10.1016/0014-2999(90)90274-A |
0.352 |
|
| 1990 |
Reynolds IJ, Rush EA, Aizenman E. Reduction of NMDA receptors with dithiothreitol increases [3H]-MK-801 binding and NMDA-induced Ca2+ fluxes. British Journal of Pharmacology. 101: 178-82. PMID 2149291 DOI: 10.1111/J.1476-5381.1990.Tb12109.X |
0.765 |
|
| 1990 |
Aizenman E, Hartnett KA, Reynolds IJ. Oxygen free radicals regulate NMDA receptor function via a redox modulatory site. Neuron. 5: 841-6. PMID 2148489 DOI: 10.1016/0896-6273(90)90343-E |
0.733 |
|
| 1990 |
Reynolds IJ, Miller RJ. Allosteric modulation of N-methyl-D-aspartate receptors. Advances in Pharmacology (San Diego, Calif.). 21: 101-26. PMID 2148268 DOI: 10.1016/S1054-3589(08)60340-3 |
0.345 |
|
| 1990 |
Reynolds IJ. Modulation of NMDA receptor responsiveness by neurotransmitters, drugs and chemical modification. Life Sciences. 47: 1785-92. PMID 1979653 DOI: 10.1016/0024-3205(90)90280-5 |
0.376 |
|
| 1990 |
Lehmann J, Randle JCR, Reynolds IJ. Excitatory amino acid receptors: NMDA modulatory sites, kainate cloned and a new role in AIDS Trends in Pharmacological Sciences. 11: 1-3. DOI: 10.1016/0165-6147(90)90031-3 |
0.327 |
|
| 1989 |
Reynolds IJ, Miller RJ. Muscarinic agonists cause calcium influx and calcium mobilization in forebrain neurons in vitro. Journal of Neurochemistry. 53: 226-33. PMID 2723657 DOI: 10.1111/J.1471-4159.1989.Tb07318.X |
0.415 |
|
| 1989 |
Reynolds IJ, Miller RJ. Ifenprodil is a novel type of N-methyl-D-aspartate receptor antagonist: interaction with polyamines. Molecular Pharmacology. 36: 758-65. PMID 2555674 |
0.307 |
|
| 1989 |
Wagner JA, Weisman HF, Snowman AM, Reynolds IJ, Weisfeldt ML, Snyder SH. Alterations in calcium antagonist receptors and sodium-calcium exchange in cardiomyopathic hamster tissues. Circulation Research. 65: 205-14. PMID 2544319 DOI: 10.1161/01.Res.65.1.205 |
0.437 |
|
| 1989 |
Reynolds IJ, Harris KM, Miller RJ. NMDA receptor antagonists that bind to the strychnine-insensitive glycine site and inhibit NMDA-induced Ca2+ fluxes and [3H]GABA release. European Journal of Pharmacology. 172: 9-17. PMID 2541002 DOI: 10.1016/0922-4106(89)90040-0 |
0.432 |
|
| 1988 |
Reynolds IJ, Miller RJ. Tricyclic antidepressants block N-methyl-D-aspartate receptors: similarities to the action of zinc. British Journal of Pharmacology. 95: 95-102. PMID 2905906 DOI: 10.1111/J.1476-5381.1988.Tb16552.X |
0.369 |
|
| 1988 |
Reynolds IJ, Snyder SH. Calcium antagonist receptors. Ion Channels. 1: 213-49. PMID 2856492 DOI: 10.1007/978-1-4615-7302-9_6 |
0.418 |
|
| 1988 |
Reynolds IJ, Miller RJ. [3H]MK801 binding to the NMDA receptor/ionophore complex is regulated by divalent cations: evidence for multiple regulatory sites. European Journal of Pharmacology. 151: 103-12. PMID 2843387 DOI: 10.1016/0014-2999(88)90697-8 |
0.416 |
|
| 1988 |
Wagner JA, Guggino SE, Reynolds IJ, Snowman AM, Biswas A, Olivera BM, Snyder SH. Calcium antagonist receptors. Clinical and physiological relevance. Annals of the New York Academy of Sciences. 522: 116-33. PMID 2454047 DOI: 10.1111/J.1749-6632.1988.Tb33349.X |
0.421 |
|
| 1987 |
Reynolds IJ, Murphy SN, Miller RJ. 3H-labeled MK-801 binding to the excitatory amino acid receptor complex from rat brain is enhanced by glycine. Proceedings of the National Academy of Sciences of the United States of America. 84: 7744-8. PMID 2823273 DOI: 10.1073/Pnas.84.21.7744 |
0.408 |
|
| 1987 |
Wagner JA, Reynolds IJ, Snyder SH. Physiological and Pharmacological Correlates of Calcium Antagonist Receptors Journal of Cardiovascular Pharmacology. 10: S1-9. DOI: 10.1097/00005344-198706110-00002 |
0.502 |
|
| 1986 |
Wagner JA, Reynolds IJ, Weisman HF, Dudeck P, Weisfeldt ML, Snyder SH. Calcium antagonist receptors in cardiomyopathic hamster: selective increases in heart, muscle, brain. Science (New York, N.Y.). 232: 515-8. PMID 3008330 DOI: 10.1126/Science.3008330 |
0.422 |
|
| 1986 |
Reynolds IJ, Wagner JA, Snyder SH, Thayer SA, Olivera BM, Miller RJ. Brain voltage-sensitive calcium channel subtypes differentiated by omega-conotoxin fraction GVIA. Proceedings of the National Academy of Sciences of the United States of America. 83: 8804-7. PMID 2430302 DOI: 10.1073/Pnas.83.22.8804 |
0.511 |
|
| 1985 |
Snyder SH, Reynolds IJ. Calcium-antagonist drugs. Receptor interactions that clarify therapeutic effects. The New England Journal of Medicine. 313: 995-1002. PMID 2413355 DOI: 10.1056/Nejm198510173131606 |
0.397 |
|
| 1984 |
Gould RJ, Murphy KM, Reynolds IJ, Snyder SH. Calcium channel blockade: possible explanation for thioridazine's peripheral side effects. The American Journal of Psychiatry. 141: 352-7. PMID 6322598 DOI: 10.1176/Ajp.141.3.352 |
0.416 |
|
| 1984 |
Gould RJ, Murphy KMM, Reynolds IJ, Snyder SH. Calcium channel blockade Journal of Clinical Psychopharmacology. 4: 232. DOI: 10.1097/00004714-198408000-00018 |
0.371 |
|
| 1983 |
Gould RJ, Murphy KM, Reynolds IJ, Snyder SH. Antischizophrenic drugs of the diphenylbutylpiperidine type act as calcium channel antagonists. Proceedings of the National Academy of Sciences of the United States of America. 80: 5122-5. PMID 6136040 DOI: 10.1073/Pnas.80.16.5122 |
0.419 |
|
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