Tim R. Mosmann - Publications

Affiliations: 
University of Rochester, Rochester, NY 
Area:
Cell Biology, Microbiology Biology

145 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Tourtelot E, Quataert S, Glantz JC, Perlis L, Muthukrishnan G, Mosmann T. Women who received varicella vaccine versus natural infection have different long-term T cell immunity but similar antibody levels. Vaccine. PMID 31959424 DOI: 10.1016/J.Vaccine.2019.12.067  0.304
2019 Cossarizza A, Chang HD, Radbruch A, Acs A, Adam D, Adam-Klages S, Agace WW, Aghaeepour N, Akdis M, Allez M, Almeida LN, Alvisi G, Anderson G, Andrä I, Annunziato F, ... ... Mosmann TR, et al. Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition). European Journal of Immunology. 49: 1457-1973. PMID 31633216 DOI: 10.1002/Eji.201970107  0.32
2017 Cossarizza A, Chang HD, Radbruch A, Andrä I, Annunziato F, Bacher P, Barnaba V, Battistini L, Bauer WM, Baumgart S, Becher B, Beisker W, Berek C, Blanco A, Borsellino G, ... ... Mosmann TR, et al. Guidelines for the use of flow cytometry and cell sorting in immunological studies. European Journal of Immunology. 47: 1584-1797. PMID 29023707 DOI: 10.1002/Eji.201646632  0.41
2017 Pedersen NW, Chandran PA, Qian Y, Rebhahn J, Petersen NV, Hoff MD, White S, Lee AJ, Stanton R, Halgreen C, Jakobsen K, Mosmann T, Gouttefangeas C, Chan C, Scheuermann RH, et al. Automated Analysis of Flow Cytometry Data to Reduce Inter-Lab Variation in the Detection of Major Histocompatibility Complex Multimer-Binding T Cells. Frontiers in Immunology. 8: 858. PMID 28798746 DOI: 10.3389/Fimmu.2017.00858  0.43
2017 Basha S, Kaur R, Mosmann TR, Pichichero ME. Reduced Th17 responses to Streptococcus pneumoniae in infection-prone children can be rescued by addition of innate cytokines. The Journal of Infectious Diseases. PMID 28201637 DOI: 10.1093/Infdis/Jix090  0.393
2015 Aghaeepour N, Chattopadhyay P, Chikina M, Dhaene T, Van Gassen S, Kursa M, Lambrecht BN, Malek M, Qian Y, Qiu P, Saeys Y, Stanton R, Tong D, Vens C, Walkowiak S, ... ... Mosmann T, et al. A benchmark for evaluation of algorithms for identification of cellular correlates of clinical outcomes. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 26447924 DOI: 10.1002/Cyto.A.22732  0.328
2015 Rebhahn JA, Roumanes DR, Qi Y, Khan A, Thakar J, Rosenberg A, Lee FE, Quataert SA, Sharma G, Mosmann TR. Competitive SWIFT cluster templates enhance detection of aging changes. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 26441030 DOI: 10.1002/Cyto.A.22740  0.519
2015 Deng N, Mosmann TR. Optimization of the cytokine secretion assay for human IL-2 in single and combination assays. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 87: 777-83. PMID 25919308 DOI: 10.1002/Cyto.A.22668  0.561
2014 Miao H, Sangster MY, Livingstone AM, Hilchey SP, Zhang L, Topham DJ, Mosmann TR, Holden-Wiltse J, Perelson AS, Wu H, Zand MS. Modeling the dynamics and migratory pathways of virus-specific antibody-secreting cell populations in primary influenza infection. Plos One. 9: e104781. PMID 25171166 DOI: 10.1371/Journal.Pone.0104781  0.34
2014 Bobo B, Phelan D, Rebhahn J, Piepenbrink MS, Zheng B, Mosmann TR, Kobie JJ, DeLouise LA. Microbubble array diffusion assay for the detection of cell secreted factors. Lab On a Chip. 14: 3640-50. PMID 25079889 DOI: 10.1039/C4Lc00580E  0.401
2014 Rebhahn JA, Deng N, Sharma G, Livingstone AM, Huang S, Mosmann TR. An animated landscape representation of CD4+ T-cell differentiation, variability, and plasticity: insights into the behavior of populations versus cells. European Journal of Immunology. 44: 2216-29. PMID 24945794 DOI: 10.1002/Eji.201444645  0.579
2014 Deng N, Weaver JM, Mosmann TR. Cytokine diversity in the Th1-dominated human anti-influenza response caused by variable cytokine expression by Th1 cells, and a minor population of uncommitted IL-2+IFNγ- Thpp cells. Plos One. 9: e95986. PMID 24788814 DOI: 10.1371/Journal.Pone.0095986  0.626
2014 Mosmann TR, Naim I, Rebhahn J, Datta S, Cavenaugh JS, Weaver JM, Sharma G. SWIFT-scalable clustering for automated identification of rare cell populations in large, high-dimensional flow cytometry datasets, part 2: biological evaluation. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 85: 422-33. PMID 24532172 DOI: 10.1002/Cyto.A.22445  0.317
2013 Sharma SK, Roumanes D, Almudevar A, Mosmann TR, Pichichero ME. CD4+ T-cell responses among adults and young children in response to Streptococcus pneumoniae and Haemophilus influenzae vaccine candidate protein antigens. Vaccine. 31: 3090-7. PMID 23632305 DOI: 10.1016/J.Vaccine.2013.03.060  0.445
2013 Weaver JM, Yang H, Roumanes D, Lee FE, Wu H, Treanor JJ, Mosmann TR. Increase in IFNγ(-)IL-2(+) cells in recent human CD4 T cell responses to 2009 pandemic H1N1 influenza. Plos One. 8: e57275. PMID 23526940 DOI: 10.1371/Journal.Pone.0057275  0.489
2012 Qi Y, Operario DJ, Georas SN, Mosmann TR. The acute environment, rather than T cell subset pre-commitment, regulates expression of the human T cell cytokine amphiregulin. Plos One. 7: e39072. PMID 22720031 DOI: 10.1371/Journal.Pone.0039072  0.667
2012 Li X, Miao H, Henn A, Topham DJ, Wu H, Zand MS, Mosmann TR. Ki-67 expression reveals strong, transient influenza specific CD4 T cell responses after adult vaccination. Vaccine. 30: 4581-4. PMID 22554464 DOI: 10.1016/J.Vaccine.2012.04.059  0.366
2011 Wu H, Kumar A, Miao H, Holden-Wiltse J, Mosmann TR, Livingstone AM, Belz GT, Perelson AS, Zand MS, Topham DJ. Modeling of influenza-specific CD8+ T cells during the primary response indicates that the spleen is a major source of effectors. Journal of Immunology (Baltimore, Md. : 1950). 187: 4474-82. PMID 21948988 DOI: 10.4049/Jimmunol.1101443  0.449
2010 Qi Y, Operario DJ, Oberholzer CM, Kobie JJ, Looney RJ, Georas SN, Mosmann TR. Human basophils express amphiregulin in response to T cell-derived IL-3. The Journal of Allergy and Clinical Immunology. 126: 1260-6.e4. PMID 21036386 DOI: 10.1016/J.Jaci.2010.08.040  0.654
2010 Qian Y, Wei C, Eun-Hyung Lee F, Campbell J, Halliley J, Lee JA, Cai J, Kong YM, Sadat E, Thomson E, Dunn P, Seegmiller AC, Karandikar NJ, Tipton CM, Mosmann T, et al. Elucidation of seventeen human peripheral blood B-cell subsets and quantification of the tetanus response using a density-based method for the automated identification of cell populations in multidimensional flow cytometry data. Cytometry. Part B, Clinical Cytometry. 78: S69-82. PMID 20839340 DOI: 10.1002/Cyto.B.20554  0.354
2010 Miao H, Hollenbaugh JA, Zand MS, Holden-Wiltse J, Mosmann TR, Perelson AS, Wu H, Topham DJ. Quantifying the early immune response and adaptive immune response kinetics in mice infected with influenza A virus. Journal of Virology. 84: 6687-98. PMID 20410284 DOI: 10.1128/Jvi.00266-10  0.382
2009 Hilchey SP, Kobie JJ, Cochran MR, Secor-Socha S, Wang JC, Hyrien O, Burack WR, Mosmann TR, Quataert SA, Bernstein SH. Human follicular lymphoma CD39+-infiltrating T cells contribute to adenosine-mediated T cell hyporesponsiveness. Journal of Immunology (Baltimore, Md. : 1950). 183: 6157-66. PMID 19864600 DOI: 10.4049/Jimmunol.0900475  0.461
2009 Henn AD, Rebhahn J, Brown MA, Murphy AJ, Coca MN, Hyrien O, Pellegrin T, Mosmann T, Zand MS. Modulation of single-cell IgG secretion frequency and rates in human memory B cells by CpG DNA, CD40L, IL-21, and cell division. Journal of Immunology (Baltimore, Md. : 1950). 183: 3177-87. PMID 19675172 DOI: 10.4049/Jimmunol.0804233  0.435
2009 Friedberg JW, Kelly JL, Neuberg D, Peterson DR, Kutok JL, Salloum R, Brenn T, Fisher DC, Ronan E, Dalton V, Rich L, Marquis D, Sims P, Rothberg PG, Liesveld J, ... ... Mosmann T, et al. Phase II study of a TLR-9 agonist (1018 ISS) with rituximab in patients with relapsed or refractory follicular lymphoma. British Journal of Haematology. 146: 282-91. PMID 19519691 DOI: 10.1111/J.1365-2141.2009.07773.X  0.425
2009 Lee HY, Topham DJ, Park SY, Hollenbaugh J, Treanor J, Mosmann TR, Jin X, Ward BM, Miao H, Holden-Wiltse J, Perelson AS, Zand M, Wu H. Simulation and prediction of the adaptive immune response to influenza A virus infection. Journal of Virology. 83: 7151-65. PMID 19439465 DOI: 10.1128/Jvi.00098-09  0.438
2009 Seavey MM, Mosmann TR. Estradiol-induced vaginal mucus inhibits antigen penetration and CD8(+) T cell priming in response to intravaginal immunization. Vaccine. 27: 2342-9. PMID 19428849 DOI: 10.1016/J.Vaccine.2009.02.025  0.764
2009 Lee HY, Hawkins E, Zand MS, Mosmann T, Wu H, Hodgkin PD, Perelson AS. Interpreting CFSE obtained division histories of B cells in vitro with Smith-Martin and cyton type models. Bulletin of Mathematical Biology. 71: 1649-70. PMID 19381725 DOI: 10.1007/S11538-009-9418-6  0.419
2009 Mosmann TR, Kobie JJ, Lee FE, Quataert SA. T helper cytokine patterns: defined subsets, random expression, and external modulation. Immunologic Research. 45: 173-84. PMID 19198763 DOI: 10.1007/S12026-009-8098-5  0.462
2009 Hilchey SP, Hyrien O, Mosmann TR, Livingstone AM, Friedberg JW, Young F, Fisher RI, Kelleher RJ, Bankert RB, Bernstein SH. Rituximab immunotherapy results in the induction of a lymphoma idiotype-specific T-cell response in patients with follicular lymphoma: support for a "vaccinal effect" of rituximab. Blood. 113: 3809-12. PMID 19196657 DOI: 10.1182/Blood-2008-10-185280  0.415
2009 Wang JC, Kobie JJ, Zhang L, Cochran M, Mosmann TR, Ritchlin CT, Quataert SA. An 11-color flow cytometric assay for identifying, phenotyping, and assessing endocytic ability of peripheral blood dendritic cell subsets in a single platform. Journal of Immunological Methods. 341: 106-16. PMID 19049809 DOI: 10.1016/J.Jim.2008.11.002  0.4
2009 Hilchey SP, Kobie JJ, Cochran MR, Secor-Socha S, Wang JE, Hyrien O, Burack WR, Mosmann TR, Quataert SA, Bernstein SH. Increased Proportions of CD39+ Infiltrating T-Cells Contribute to Adenosine Mediated T-Cell Hypo-Responsiveness within Human Follicular Lymphoma. Blood. 114: 758-758. DOI: 10.1182/Blood.V114.22.758.758  0.449
2008 Zaiss DM, Sijts AJ, Mosmann TR. Enumeration of cytotoxic CD8 T cells ex vivo during the response to Listeria monocytogenes infection. Infection and Immunity. 76: 4609-14. PMID 18678661 DOI: 10.1128/Iai.00563-08  0.493
2008 Rebhahn JA, Bishop C, Divekar AA, Jiminez-Garcia K, Kobie JJ, Lee FE, Maupin GM, Snyder-Cappione JE, Zaiss DM, Mosmann TR. Automated analysis of two- and three-color fluorescent Elispot (Fluorospot) assays for cytokine secretion. Computer Methods and Programs in Biomedicine. 92: 54-65. PMID 18644656 DOI: 10.1016/J.Cmpb.2008.06.002  0.42
2008 Mosmann T. Measurement of mouse and human interleukin 10. Current Protocols in Immunology. Unit 6.14. PMID 18432805 DOI: 10.1002/0471142735.Im0614S18  0.46
2008 Seavey MM, Mosmann TR. Immunoregulation of fetal and anti-paternal immune responses. Immunologic Research. 40: 97-113. PMID 18213524 DOI: 10.1007/S12026-007-8005-X  0.718
2007 Richter M, Ray SJ, Chapman TJ, Austin SJ, Rebhahn J, Mosmann TR, Gardner H, Kotelianski V, deFougerolles AR, Topham DJ. Collagen distribution and expression of collagen-binding alpha1beta1 (VLA-1) and alpha2beta1 (VLA-2) integrins on CD4 and CD8 T cells during influenza infection. Journal of Immunology (Baltimore, Md. : 1950). 178: 4506-16. PMID 17372009 DOI: 10.4049/Jimmunol.178.7.4506  0.411
2006 Zaiss DM, Yang L, Shah PR, Kobie JJ, Urban JF, Mosmann TR. Amphiregulin, a TH2 cytokine enhancing resistance to nematodes. Science (New York, N.Y.). 314: 1746. PMID 17170297 DOI: 10.1126/Science.1133715  0.452
2006 Seavey MM, Mosmann TR. Paternal antigen-bearing cells transferred during insemination do not stimulate anti-paternal CD8+ T cells: role of estradiol in locally inhibiting CD8+ T cell responses. Journal of Immunology (Baltimore, Md. : 1950). 177: 7567-78. PMID 17114426 DOI: 10.4049/Jimmunol.177.11.7567  0.766
2006 Kobie JJ, Shah PR, Yang L, Rebhahn JA, Fowell DJ, Mosmann TR. T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5'-adenosine monophosphate to adenosine. Journal of Immunology (Baltimore, Md. : 1950). 177: 6780-6. PMID 17082591 DOI: 10.4049/Jimmunol.177.10.6780  0.5
2006 Snyder-Cappione JE, Divekar AA, Maupin GM, Jin X, Demeter LM, Mosmann TR. HIV-specific cytotoxic cell frequencies measured directly ex vivo by the Lysispot assay can be higher or lower than the frequencies of IFN-gamma-secreting cells: anti-HIV cytotoxicity is not generally impaired relative to other chronic virus responses. Journal of Immunology (Baltimore, Md. : 1950). 176: 2662-8. PMID 16456029 DOI: 10.4049/Jimmunol.176.4.2662  0.368
2006 Divekar AA, Zaiss DM, Lee FE, Liu D, Topham DJ, Sijts AJ, Mosmann TR. Protein vaccines induce uncommitted IL-2-secreting human and mouse CD4 T cells, whereas infections induce more IFN-gamma-secreting cells. Journal of Immunology (Baltimore, Md. : 1950). 176: 1465-73. PMID 16424174 DOI: 10.4049/Jimmunol.176.3.1465  0.515
2006 Friedberg JW, Kelly J, Kutok JL, Salloum R, Fisher DC, Ronan E, Dalton V, Rich L, Marquis D, Rothberg PG, Liesveld J, Fisher RI, Coffman R, Mosmann T, Freedman AS. Combination Immunotherapy with a CpG Oligonucleotide and Rituximab (R) Augments the Immunological Response and Favorably Alters the Malignant Microenvironment of Follicular Lymphoma (FL). Blood. 108: 2713-2713. DOI: 10.1182/Blood.V108.11.2713.2713  0.382
2005 Yang L, Kobie JJ, Mosmann TR. CD73 and Ly-6A/E distinguish in vivo primed but uncommitted mouse CD4 T cells from type 1 or type 2 effector cells. Journal of Immunology (Baltimore, Md. : 1950). 175: 6458-64. PMID 16272299 DOI: 10.4049/Jimmunol.175.10.6458  0.485
2005 Lee FE, Walsh EE, Falsey AR, Liu N, Liu D, Divekar A, Snyder-Cappione JE, Mosmann TR. The balance between influenza- and RSV-specific CD4 T cells secreting IL-10 or IFNgamma in young and healthy-elderly subjects. Mechanisms of Ageing and Development. 126: 1223-9. PMID 16098562 DOI: 10.1016/J.Mad.2005.06.011  0.425
2005 Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. 1986 Journal of Immunology (Baltimore, Md. : 1950). 175: 5-14. PMID 15972624  0.306
2005 Chaouat G, Meliani AA, Martal J, Raghupathy R, Elliot J, Mosmann T, Wegmann TG. IL-10 prevents naturally occurring fetal loss in the CBA x DBA/2 mating combination, and local defect in IL-10 production in this abortion-prone combination is corrected by in vivo injection of IFN-tau. Journal of Immunology. 154: 4261-4268. DOI: 10.4049/Jimmunol.175.5.3447-D  0.355
2005 Friedberg JW, Kelly J, Kutok JL, Salloum R, Brenn T, Fisher DC, Ronan E, McCauley M, Rich L, Marquis D, Rothberg PG, Liesveld J, Fisher RI, Coffman R, Mosmann T, et al. CpG Oligonucleotide (1018 ISS) May Overcome Rituximab (R) Resistance in Follicular Lymphoma (FL) through Enhanced ADCC, T Cell Expansion, and Alteration of Tumor Microenvironment. Blood. 106: 2434-2434. DOI: 10.1182/Blood.V106.11.2434.2434  0.423
2004 Mosmann TR, Livingstone AM. Dendritic cells: the immune information management experts. Nature Immunology. 5: 564-6. PMID 15164014 DOI: 10.1038/Ni0604-564  0.436
2004 Yang L, Mosmann T. Synthesis of several chemokines but few cytokines by primed uncommitted precursor CD4 T cells suggests that these cells recruit other immune cells without exerting direct effector functions. European Journal of Immunology. 34: 1617-26. PMID 15162431 DOI: 10.1002/Eji.200424939  0.541
2003 Snyder JE, Mosmann TR. How to "spot" a real killer. Trends in Immunology. 24: 231; author reply 23. PMID 12738412 DOI: 10.1016/S1471-4906(03)00077-2  0.437
2003 Snyder JE, Bowers WJ, Livingstone AM, Lee FE, Federoff HJ, Mosmann TR. Measuring the frequency of mouse and human cytotoxic T cells by the Lysispot assay: independent regulation of cytokine secretion and short-term killing. Nature Medicine. 9: 231-5. PMID 12539041 DOI: 10.1038/Nm821  0.485
2001 Wang X, Mosmann T. In vivo priming of CD4 T cells that produce interleukin (IL)-2 but not IL-4 or interferon (IFN)-gamma, and can subsequently differentiate into IL-4- or IFN-gamma-secreting cells. The Journal of Experimental Medicine. 194: 1069-80. PMID 11602637 DOI: 10.1084/Jem.194.8.1069  0.512
2000 Mosmann T. Complexity or coherence? Cytokine secretion by B cells. Nature Immunology. 1: 465-466. PMID 11101865 DOI: 10.1038/82707  0.427
2000 Mosmann T. Reply to Cohen Immunology Today. 21: 199. PMID 10740245 DOI: 10.1016/S0167-5699(00)01587-5  0.497
1999 Akai PS, Mosmann TR. Primed and replicating but uncommitted T helper precursor cells show kinetics of differentiation and commitment similar to those of naive T helper cells Microbes and Infection. 1: 51-58. PMID 10847766 DOI: 10.1016/S1286-4579(99)80014-8  0.45
1999 Lai YH, Mosmann TR. Mouse IL-13 enhances antibody production in vivo and acts directly on B cells in vitro to increase survival and hence antibody production Journal of Immunology. 162: 78-87. PMID 9886372  0.325
1999 Liu MF, Ning Q, Pope M, Mosmann T, Leibowitz J, Ding JW, Fung LS, Rotstein O, Gorczynski R, Levy GA. Resistance of naive mice to murine hepatitis virus strain 3 requires development of a Th1, but not a Th2, response, whereas pre-existing antibody partially protects against primary infection. Advances in Experimental Medicine and Biology. 440: 415-23. PMID 9782309 DOI: 10.1007/978-1-4615-5331-1_52  0.394
1997 Sad S, Li L, Mosmann TR. Cytokine-Deficient CD8+ Tc1 Cells Induced by IL-4: Retained Inflammation and Perforin and Fas Cytotoxicity but Compromised Long Term Killing of Tumor Cells Journal of Immunology. 159: 606-613. PMID 9218575  0.361
1997 Mosmann TR, Li L, Sad S. Functions of CD8 T-cell subsets secreting different cytokine patterns Seminars in Immunology. 9: 87-92. PMID 9194219 DOI: 10.1006/Smim.1997.0065  0.529
1997 Sad S, Krishnan L, Bleackley RC, Kägi D, Hengartner H, Mosmann TR. Cytotoxicity and weak CD40 ligand expression of CD8+ type 2 cytotoxic T cells restricts their potential B cell helper activity. European Journal of Immunology. 27: 914-22. PMID 9130644 DOI: 10.1002/Eji.1830270417  0.488
1997 Li L, Sad S, Kägi D, Mosmann TR. CD8Tc1 and Tc2 Cells Secrete Distinct Cytokine Patterns in Vitro and in Vivo but Induce Similar Inflammatory Reactions Journal of Immunology. 158: 4152-4161. PMID 9126975  0.436
1997 Mosmann TR, Li L, Hengartner H, Kagi D, Fu W, Sad S. Differentiation and functions of T cell subsets. Ciba Foundation Symposium. 204: 148-54; discussion 1. PMID 9107418  0.435
1996 Sad S, Kägi D, Mosmann TR. Perforin and Fas killing by CD8+ T cells limits their cytokine synthesis and proliferation Journal of Experimental Medicine. 184: 1543-1547. PMID 8879227 DOI: 10.1084/Jem.184.4.1543  0.504
1996 Madsen KL, Tavernini MM, Mosmann TR, Fedorak RN. Interleukin 10 modulates ion transport in rat small intestine Gastroenterology. 111: 936-944. PMID 8831588 DOI: 10.1016/S0016-5085(96)70061-6  0.33
1996 Suarez-Pinzon W, Rajotte RV, Mosmann TR, Rabinovitch A. Both CD4+ and CD8+ T-cells in syngeneic islet grafts in NOD mice produce interferon-γ during β-cell destruction Diabetes. 45: 1350-1357. PMID 8826970  0.343
1996 Mosmann TR, Sad S. The expanding universe of T-cell subsets: Th1, Th2 and more Immunology Today. 17: 138-146. PMID 8820272 DOI: 10.1016/0167-5699(96)80606-2  0.512
1995 Mosmann TR, Sad S, Krishnan L, Wegmann TG, Guilbert LJ, Belosevic M. Differentiation of subsets of CD4+ and CD8+ T cells. Ciba Foundation Symposium. 195: 42-50; discussion 50. PMID 8724829  0.427
1995 Sad S, Marcotte R, Mosmann TR. Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ T cells secreting Th1 or Th2 cytokines Immunity. 2: 271-279. PMID 7697544 DOI: 10.1016/1074-7613(95)90051-9  0.493
1995 Sad S, Mosmann TR. Interleukin (IL) 4, in the absence of antigen stimulation, induces an anergy-like state in differentiated CD8+ TC1 cells: Loss of IL-2 synthesis and autonomous proliferation but retention of cytotoxicity and synthesis of other cytokines Journal of Experimental Medicine. 182: 1505-1515. PMID 7595220 DOI: 10.1084/Jem.182.5.1505  0.472
1995 Mosmann TR. Cytokines, differentiation and functions of subsets of CD4 and CD8 T cells Behring Institute Mitteilungen. 1-6. PMID 7575345  0.301
1994 Sad S, Mosmann TR. Single IL-2-secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype Journal of Immunology. 153: 3514-3522. PMID 7930573  0.413
1994 Sad S, Marcotte R, Mosmann T. IL4 induces differentiation of cytotoxic CD8+ T cells secreting TH2 cytokines Cytokine. 6: 575. DOI: 10.1016/1043-4666(94)90296-8  0.496
1994 Li L, Elliott JF, Mosmann TR. IL10 inhibits cytokine production and edema during TH1-induced delayed type hypersensitivity (DTH) Cytokine. 6: 575. DOI: 10.1016/1043-4666(94)90295-X  0.352
1993 Lin H, Mosmann TR, Guilbert L, Tuntipopipat S, Wegmann TG. Synthesis of T helper 2-type cytokines at the maternal-fetal interface Journal of Immunology. 151: 4562-4573. PMID 8409418  0.33
1993 Moore KW, O'Garra A, de Waal Malefyt R, Vieira P, Mosmann TR. Interleukin-10. Annual Review of Immunology. 11: 165-90. PMID 8386517 DOI: 10.1146/annurev.iy.11.040193.001121  0.335
1993 Yang X, Gieni RS, Mosmann TR, HayGlass KT. Chemically modified antigen preferentially elicits induction of Th1-like cytokine synthesis patterns in Vivo Journal of Experimental Medicine. 178: 349-353. PMID 8315390 DOI: 10.1084/Jem.178.1.349  0.455
1993 Wegmann TG, Lin H, Guilbert L, Mosmann TR. Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon? Trends in Immunology. 14: 353-356. DOI: 10.1016/0167-5699(93)90235-D  0.366
1992 Paul WE, Kishimoto T, Melchers F, Metcalf D, Mosmann T, Oppenheim J, Ruddle N, Van Snick J. Nomenclature for secreted regulatory proteins of the immune system (interleukins). WHO-IUIS Nomenclature Subcommittee on Interleukin Designation. Clinical and Experimental Immunology. 88: 367. PMID 1572103 DOI: 10.1111/J.1365-2249.1992.Tb03089.X  0.315
1992 Mosmann TR. T lymphocyte subsets, cytokines, and effector functions Annals of the New York Academy of Sciences. 664: 89-92. PMID 1456670 DOI: 10.1111/J.1749-6632.1992.Tb39751.X  0.418
1992 Sher A, Gazzinelli RT, Oswald IP, Clerici M, Kullberg M, Pearce EJ, Berzofsky JA, Mosmann TR, James SL, Morse HC, Shearer GM. Role of T-cell derived cytokines in the downregulation of immune responses in parasitic and retroviral infection Immunological Reviews. 183-204. PMID 1354651 DOI: 10.1111/J.1600-065X.1992.Tb01414.X  0.452
1992 Bloemkolk JW, Gray MR, Merchant F, Mosmann TR. Effect of temperature on hybridoma cell cycle and MAb production Biotechnology and Bioengineering. 40: 427-431. DOI: 10.1002/Bit.260400312  0.326
1991 Sadick MD, Street N, Mosmann TR, Locksley RM. Cytokine regulation of murine leishmaniasis: Interleukin 4 is not sufficient to mediate progressive disease in resistant C57BL/6 mice Infection and Immunity. 59: 4710-4714. PMID 1937832 DOI: 10.1128/Iai.59.12.4710-4714.1991  0.326
1991 Mosmann TR. Cytokines: is there biological meaning? Current Opinion in Immunology. 3: 311-314. PMID 1910608 DOI: 10.1016/0952-7915(91)90029-Z  0.305
1991 Budd RC, Schumacher JH, Winslow G, Mosmann TR. Elevated production of interferon-γ and interleukin 4 by mature T cells from autoimmune lpr mice correlates with Pgp-1 (CD44) expression European Journal of Immunology. 21: 1081-1084. PMID 1902176 DOI: 10.1002/Eji.1830210435  0.511
1991 Thompson-Snipes L, Dhar V, Bond MW, Mosmann TR, Moore KW, Rennick DM. Interleukin 10: a novel stimulatory factor for mast cells and their progenitors. The Journal of Experimental Medicine. 173: 507-10. PMID 1899106 DOI: 10.1084/Jem.173.2.507  0.41
1991 Vieira P, de Waal-Malefyt R, Dang MN, Johnson KE, Kastelein R, Fiorentino DF, deVries JE, Roncarolo MG, Mosmann TR, Moore KW. Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI. Proceedings of the National Academy of Sciences of the United States of America. 88: 1172-6. PMID 1847510 DOI: 10.1073/Pnas.88.4.1172  0.41
1991 Mosmann TR. Cytokine secretion phenotypes of TH cells: how many subsets, how much regulation? Research in Immunology. 142: 9-13. PMID 1829264 DOI: 10.1016/0923-2494(91)90003-2  0.418
1991 Coffman RL, Mosmann TR. CD4+ T-cell subsets: regulation of differentiation and function Research in Immunology. 142: 7-9. PMID 1829263 DOI: 10.1016/0923-2494(91)90002-Z  0.377
1991 Fiorentino DF, Zlotnik A, Vieira P, Mosmann TR, Howard M, Moore KW, O'Garra A. IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells. Journal of Immunology (Baltimore, Md. : 1950). 146: 3444-51. PMID 1827484  0.344
1991 Street NE, Mosmann TR. Functional diversity of T lymphocytes due to secretion of different cytokine patterns Faseb Journal. 5: 171-177. PMID 1825981 DOI: 10.1096/Fasebj.5.2.1825981  0.525
1991 Kupfer A, Mosmann TR, Kupfer H. Polarized expression of cytokines in cell conjugates of helper T cells and splenic B cells Proceedings of the National Academy of Sciences of the United States of America. 88: 775-779. PMID 1825141 DOI: 10.1073/Pnas.88.3.775  0.489
1991 Mosmann TR, Schumacher JH, Street NF, Budd R, O'Garra A, Fong TA, Bond MW, Moore KW, Sher A, Fiorentino DF. Diversity of cytokine synthesis and function of mouse CD4+ T cells. Immunological Reviews. 123: 209-29. PMID 1684780 DOI: 10.1111/J.1600-065X.1991.Tb00612.X  0.458
1991 Mosmann TR. Cytokine secretion patterns and cross-regulation of T cell subsets Immunologic Research. 10: 183-188. PMID 1659603 DOI: 10.1007/Bf02919690  0.483
1991 Mosmann TR. Regulation of immune responses by T cells with different cytokine secretion phenotypes: Role of a new cytokine, cytokine synthesis inhibitory factor (IL10) International Archives of Allergy and Applied Immunology. 94: 110-115. PMID 1657790 DOI: 10.1159/000235340  0.469
1991 Mosmann TR, Moore KW. The role of IL-10 in crossregulation of TH1 and TH2 responses. Immunology Today. 12: A49-53. PMID 1648926 DOI: 10.1016/S0167-5699(05)80015-5  0.471
1991 Mosmann TR. Role of a new cytokine, interleukin-10, in the cross-regulation of T helper cells Annals of the New York Academy of Sciences. 628: 337-344. PMID 1648883 DOI: 10.1111/J.1749-6632.1991.Tb17266.X  0.436
1991 Mosmann TR, Moore KW. The role of IL-10 in crossregulation of TH1 and TH2 responses Parasitology Today. 7: 49-53. DOI: 10.1016/0169-4758(91)90032-J  0.47
1990 Street NE, Mosmann TR. IL4 and IL5: The role of two multifunctional cytokines and their place in the network of cytokine interactions Biotherapy. 2: 347-362. PMID 2268500 DOI: 10.1007/Bf02170084  0.487
1990 Hsu DH, de Waal Malefyt R, Fiorentino DF, Dang MN, Vieira P, de Vries J, Spits H, Mosmann TR, Moore KW. Expression of interleukin-10 activity by Epstein-Barr virus protein BCRF1. Science (New York, N.Y.). 250: 830-2. PMID 2173142 DOI: 10.1126/Science.2173142  0.431
1990 Moore KW, Vieira P, Fiorentino DF, Trounstine ML, Khan TA, Mosmann TR. Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI. Science (New York, N.Y.). 248: 1230-4. PMID 2161559 DOI: 10.1126/Science.2161559  0.374
1990 Fong TAT, Mosmann TR. Alloreactive murine CD8+ T cell clones secrete the Th1 pattern of cytokines Journal of Immunology. 144: 1744-1752. PMID 2137843  0.336
1990 Go NF, Castle BE, Barrett R, Kastelein R, Dang W, Mosmann TR, Moore KW, Howard M. Interleukin 10, a novel B cell stimulatory factor: unresponsiveness of X chromosome-linked immunodeficiency B cells. The Journal of Experimental Medicine. 172: 1625-31. PMID 2124252 DOI: 10.1084/Jem.172.6.1625  0.435
1990 MacNeil IA, Suda T, Moore KW, Mosmann TR, Zlotnik A. IL-10, a novel growth cofactor for mature and immature T cells. Journal of Immunology (Baltimore, Md. : 1950). 145: 4167-73. PMID 2124236  0.316
1990 Street NE, Schumacher JH, Fong TAT, Bass H, Fiorentino DF, Leverah JA, Mosmann TR. Heterogeneity of mouse helper T cells: Evidence from bulk cultures and limiting dilution cloning for precursors of Th1 and Th2 cells Journal of Immunology. 144: 1629-1639. PMID 1968485  0.331
1990 O'garra A, Stapleton G, Dhar V, Pearce M, Schumacher J, Rugo H, Barbls D, Stall A, Cupp J, Moore K, Vieira P, Mosmann T, Whitmore A, Arnold L, Haughton G, et al. Production of cytokines by mouse B cells: B lymphomas and normal B cells produce interleukin 10 International Immunology. 2: 821-832. PMID 1703785 DOI: 10.1093/Intimm/2.9.821  0.423
1990 Finkelman FD, Holmes J, Katona IM, Urban JF, Beckmann MP, Park LS, Schooley KA, Coffman RL, Mosmann TR, Paul WE. Lymphokine control of in vivo immunoglobulin isotype selection. Annual Review of Immunology. 8: 303-33. PMID 1693082 DOI: 10.1146/annurev.iy.08.040190.001511  0.319
1989 Mosmann TR, Fong TAT. Specific assays for cytokine production by T cells Journal of Immunological Methods. 116: 151-158. PMID 2642947 DOI: 10.1016/0022-1759(89)90198-1  0.441
1989 Bass H, Mosmann T, Strober S. Evidence for mouse Th1- and Th2-like helper T cells in vivo. Selective reduction of Th1-like cells after total lymphoid irradiation. The Journal of Experimental Medicine. 170: 1495-511. PMID 2572669 DOI: 10.1084/Jem.170.5.1495  0.501
1989 Fiorentino DF, Bond MW, Mosmann TR. Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones Journal of Experimental Medicine. 170: 2081-20095. PMID 2531194 DOI: 10.1084/Jem.170.6.2081  0.414
1989 Mosmann TR, Coffman RL. Heterogeneity of cytokine secretion patterns and functions of helper T cells Advances in Immunology. 46: 111-147. PMID 2528896 DOI: 10.1016/S0065-2776(08)60652-5  0.512
1989 Mosmann TR, Coffman RL. TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties Annual Review of Immunology. 7: 145-173. PMID 2523712 DOI: 10.1146/Annurev.Iy.07.040189.001045  0.362
1989 DeKruyff RH, Ju ST, Hunt AJ, Mosmann TR, Umetsu DT. Induction of antigen-specific antibody responses in primed and unprimed B cells. Functional heterogeneity among Th1 and Th2 T cell clones. Journal of Immunology (Baltimore, Md. : 1950). 142: 2575-82. PMID 2522962  0.397
1988 Mosmann TR. Directional release of lymphokines from T cells Immunology Today. 9: 306-307. PMID 3267129 DOI: 10.1016/0167-5699(88)91323-0  0.389
1988 Fernandez-Botran R, Sanders VM, Mosmann TR, Vitetta ES. Lymphokine-mediated regulation of the proliferative response of clones of T helper 1 and T helper 2 cells. The Journal of Experimental Medicine. 168: 543-58. PMID 2970518 DOI: 10.1084/Jem.168.2.543  0.43
1988 Coffman RL, Mosmann TR. Isotype regulation by helper T cells and lymphokines Monographs in Allergy. 24: 96-103. PMID 2966284  0.339
1988 Sanders VM, Fernandez-Botran R, Coffman RL, Mosmann TR, Vitetta ES. A single antigen-specific B cell can conjugate to either a type 1 or a type 2 helper T cell. Proceedings of the National Academy of Sciences of the United States of America. 85: 7724-8. PMID 2459715 DOI: 10.1073/Pnas.85.20.7724  0.484
1988 Stevens TL, Bossie A, Sanders VM, Fernandez-Botran R, Coffman RL, Mosmann TR, Vitetta ES. Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells. Nature. 334: 255-8. PMID 2456466 DOI: 10.1038/334255A0  0.51
1987 Mosmann TR, Coffman RL. Two types of mouse helper T-cell clone Implications for immune regulation. Immunology Today. 8: 223-7. PMID 25290434 DOI: 10.1016/0167-5699(87)90171-X  0.505
1987 Mosmann TR, Yokota T, Kastelein R, Zurawski SM, Arai N, Takebe Y. Species-specificity of T cell stimulating activities of IL 2 and BSF-1 (IL 4): Comparison of normal and recombinant, mouse and human IL 2 and BSF-1 (IL 4) Journal of Immunology. 138: 1813-1816. PMID 3493289  0.333
1987 Rupp F, Brecher J, Giedlin MA, Mosmann T, Zinkernagel RM, Hengartner H, Joho RH. T-cell antigen receptors with identical variable regions but different diversity and joining region gene segments have distinct specificities but cross-reactive idiotypes. Proceedings of the National Academy of Sciences of the United States of America. 84: 219-22. PMID 3491990 DOI: 10.1073/Pnas.84.1.219  0.392
1987 Hu-Li J, Shevach EM, Mizuguchi J, Ohara J, Mosmann T, Paul WE. B cell stimulatory factor 1 (interleukin 4) is a potent costimulant for normal resting T lymphocytes. The Journal of Experimental Medicine. 165: 157-72. PMID 3098893 DOI: 10.1084/Jem.165.1.157  0.473
1987 Cherwinski HM, Schumacher JH, Brown KD, Mosmann TR. Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 an Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies Journal of Experimental Medicine. 166: 1229-1244. PMID 2960769 DOI: 10.1084/Jem.166.5.1229  0.448
1987 Bond MW, Shrader B, Mosmann TR, Coffman RL. A mouse T cell product that preferentially enhances IgA production. II. Physicochemical characterization Journal of Immunology. 139: 3691-3696. PMID 2960740  0.306
1987 Coffman RL, Shrader B, Carty J, Mosmann TR, Bond MW. A mouse T cell product that preferentially enhances IgA production. I. Biologic characterization Journal of Immunology. 139: 3685-3690. PMID 2960739  0.325
1987 Cher DJ, Mosmann TR. Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by T(H)1 clones Journal of Immunology. 138: 3688-3694. PMID 2953788  0.341
1987 Mosmann TR, Coffman RL. Two types of mouse helper T-cell clone. Implications for immune regulation Immunology Today. 8: 223-227. DOI: 10.1016/0167-5699(87)90171-X  0.412
1986 Mosmann TR, Bond MW, Coffman RL, Ohara J, Paul WE. T-cell and mast cell lines respond to B-cell stimulatory factor 1 Proceedings of the National Academy of Sciences of the United States of America. 83: 5654-5658. PMID 3090545 DOI: 10.1073/Pnas.83.15.5654  0.458
1986 Lee F, Yokota T, Otsuka T, Meyerson P, Villaret D, Coffman R, Mosmann T, Rennick D, Roehm N, Smith C. Isolation and characterization of a mouse interleukin cDNA clone that expresses B-cell stimulatory factor 1 activities and T-cell- and mast-cell-stimulating activities. Proceedings of the National Academy of Sciences of the United States of America. 83: 2061-5. PMID 3083412 DOI: 10.1073/Pnas.83.7.2061  0.444
1986 Yokota T, Otsuka T, Mosmann T, Banchereau J, DeFrance T, Blanchard D, De Vries JE, Lee F, Arai K. Isolation and characterization of a human interleukin cDNA clone, homologous to mouse B-cell stimulatory factor 1, that expresses B-cell- and T-cell-stimulating activities. Proceedings of the National Academy of Sciences of the United States of America. 83: 5894-8. PMID 3016727 DOI: 10.1073/Pnas.83.16.5894  0.397
1986 Giedlin MA, Longenecker BM, Mosmann TR. Murine T-cell clones specific for chicken erythrocyte alloantigens Cellular Immunology. 97: 357-370. PMID 2427220 DOI: 10.1016/0008-8749(86)90406-5  0.518
1986 Mosmann TR, Cherwinski H, Bond MW. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins Journal of Immunology. 136: 2348-2357. PMID 2419430  0.41
1985 Yokota T, Arai N, Lee F, Rennick D, Mosmann T, Arai K. Use of a cDNA expression vector for isolation of mouse interleukin 2 cDNA clones: expression of T-cell growth-factor activity after transfection of monkey cells. Proceedings of the National Academy of Sciences of the United States of America. 82: 68-72. PMID 3918306 DOI: 10.1073/Pnas.82.1.68  0.395
1984 Yokota T, Lee F, Rennick D, Hall C, Arai N, Mosmann T, Nabel G, Cantor H, Arai K. Isolation and characterization of a mouse cDNA clone that expresses mast-cell growth-factor activity in monkey cells. Proceedings of the National Academy of Sciences of the United States of America. 81: 1070-4. PMID 6322187 DOI: 10.1073/Pnas.81.4.1070  0.329
1983 Mosmann TR. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays Journal of Immunological Methods. 65: 55-63. PMID 6606682 DOI: 10.1016/0022-1759(83)90303-4  0.33
1981 Bleackley RC, Caplan B, Havele C, Ritzel RG, Mosmann TR, Farrar JJ, Paetkau V. Translation of lymphocyte mRNA into biologically-active interleukin 2 in oocytes Journal of Immunology. 127: 2432-2435. PMID 6975322  0.307
1981 Longenecker BM, Mosmann TR. Structure and properties of the major histocompatibility complex of the chicken. Speculations on the advantages and evolution of polymorphism Immunogenetics. 13: 1-23. PMID 6262224 DOI: 10.1007/Bf00524601  0.35
1980 Longenecker BM, Mosmann TR. "Natural" Antibodies to chicken MHC antigens are present in mice, rats, humans, alligators and allogeneic chickens Immunogenetics. 11: 293-302. PMID 7287080 DOI: 10.1007/Bf01567795  0.347
1980 Longenecker BM, Mosmann TR. Restricted expression of an MHC alloantigen in cells of the erythroid series: A specific marker for erythroid differentiation Journal of Supramolecular and Cellular Biochemistry. 13: 395-400. PMID 7206712 DOI: 10.1002/Jss.400130310  0.337
1979 Mosmann TR, Baumal R, Williamson AR. Mutations affecting immunoglobulin light chain secretion by myeloma cells. I. Functional analysis by cell fusion. European Journal of Immunology. 9: 511-6. PMID 115698 DOI: 10.1002/Eji.1830090705  0.353
1979 Longenecker BM, Mosmann TR, Shiozawa C. A strong, preferential response of mice to polymorphic antigenic determinants of the chicken MHC, analyzed with mouse hybridoma (monoclonal) antibodies Immunogenetics. 9: 137-147. DOI: 10.1007/Bf01570404  0.365
1978 Mosmann TR, Gravel Y, Williamson AR, Baumal R. Modification and fate of J chain in myeloma cells in the presence and absence of polymeric immunoglobulin secretion. European Journal of Immunology. 8: 94-101. PMID 95957 DOI: 10.1002/Eji.1830080205  0.325
1977 MOSMANN T, WILLIAMSON AR. Fusion of Lymphoid Cells Biochemical Society Transactions. 5: 33-33. DOI: 10.1042/Bst0050033C  0.38
1976 Mosmann T, Baumal R. Macroscopic cloning assay using complement fixation to isolate secretion variants of myeloma cells. Journal of Immunological Methods. 10: 119-125. PMID 932436 DOI: 10.1016/0022-1759(76)90162-9  0.406
1976 Hudson JB, Misra V, Mosmann TR. Cytomegalovirus infectivity: Analysis of the phenomenon of centrifugal enhancement of infectivity Virology. 72: 235-243. PMID 180669 DOI: 10.1016/0042-6822(76)90326-3  0.317
1976 Hudson JB, Misra V, Mosmann TR. Properties of the multicapsid virions of murine cytomegalovirus Virology. 72: 224-234. PMID 180668 DOI: 10.1016/0042-6822(76)90325-1  0.301
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