Sudha Biddinger - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 

30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Semova I, Levenson AE, Krawczyk J, Bullock K, Gearing ME, Ling AV, Williams KA, Miao J, Adamson SS, Shin DJ, Chahar S, Graham MJ, Crooke RM, Hagey LR, Vicent D, ... ... Biddinger SB, et al. Insulin Prevents Hypercholesterolemia by Suppressing 12a-Hydroxylated Bile Acid Production. Circulation. PMID 35193378 DOI: 10.1161/CIRCULATIONAHA.120.045373  0.364
2021 Semova I, Biddinger SB. Triglycerides in Nonalcoholic Fatty Liver Disease: Guilty Until Proven Innocent. Trends in Pharmacological Sciences. PMID 33468321 DOI: 10.1016/j.tips.2020.12.001  0.385
2019 Chen S, Henderson A, Petriello M, Romano KA, Gearing M, Miao J, Schell M, Sandoval-EspinolaEspinola WJ, Tao J, Sha B, Graham M, Crooke R, Kleinridders A, Balskus EP, Rey FE, ... ... Biddinger SB, et al. Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction. Cell Metabolism. PMID 31543404 DOI: 10.1016/J.Cmet.2019.08.021  0.306
2019 Hung YH, Kanke M, Kurtz CL, Cubitt R, Bunaciu RP, Miao J, Zhou L, Graham JL, Hussain M, Havel PJ, Biddinger SB, White PJ, Sethupathy P. Acute suppression of insulin resistance-associated hepatic miR-29 in vivo improves glycemic control in adult mice. Physiological Genomics. PMID 31251698 DOI: 10.1152/Physiolgenomics.00037.2019  0.361
2018 Meakin PJ, Mezzapesa A, Benabou E, Haas ME, Bonardo B, Grino M, Brunel JM, Desbois-Mouthon C, Biddinger SB, Govers R, Ashford MLJ, Peiretti F. The beta secretase BACE1 regulates the expression of insulin receptor in the liver. Nature Communications. 9: 1306. PMID 29610518 DOI: 10.1038/s41467-018-03755-2  0.379
2018 Meoli L, Gupta NK, Saeidi N, Panciotti C, Biddinger SB, Corey KE, Stylopoulos N. Non-alcoholic Fatty Liver Disease and Gastric Bypass Surgery Regulate Serum And Hepatic Levels of Pyruvate Kinase Isoenzyme M2. American Journal of Physiology. Endocrinology and Metabolism. PMID 29462566 DOI: 10.1152/Ajpendo.00296.2017  0.301
2017 Ling AV, Gearing ME, Semova I, Shin DJ, Clements R, Lai ZW, Biddinger SB. FoxO1 is required for most of the metabolic and hormonal perturbations produced by hepatic insulin receptor deletion in male mice. Endocrinology. PMID 29300910 DOI: 10.1210/en.2017-00870  0.469
2017 Hu Y, Semova I, Sun X, Kang H, Chahar S, Hollenberg AN, Masson D, Hirschey MD, Miao J, Biddinger SB. Fructose and glucose regulate mammalian target of rapamycin complex 1 and can activate lipogenic gene expression via distinct pathways. The Journal of Biological Chemistry. PMID 29222328 DOI: 10.1074/Jbc.M117.782557  0.303
2017 Key CC, Liu M, Kurtz CL, Chung S, Boudyguina E, Dinh TA, Bashore A, Phelan PE, Freedman BI, Osborne TF, Zhu X, Ma L, Sethupathy P, Biddinger SB, Parks JS. Hepatocyte ABCA1 Deletion Impairs Liver Insulin Signaling and Lipogenesis. Cell Reports. 19: 2116-2129. PMID 28591582 DOI: 10.1016/J.Celrep.2017.05.032  0.463
2015 Sun X, Haas ME, Miao J, Mehta A, Graham MJ, Crooke RM, de Barros JP, Wang JG, Aikawa M, Masson D, Biddinger SB. Insulin dissociates the effects of Liver X Receptor on lipogenesis, endoplasmic reticulum stress and inflammation. The Journal of Biological Chemistry. PMID 26511317 DOI: 10.1074/Jbc.M115.668269  0.371
2015 Miao J, Manthena PV, Haas ME, Ling AV, Shin DJ, Graham MJ, Crooke RM, Liu J, Biddinger SB. Role of Insulin in the Regulation of Proprotein Convertase Subtilisin/Kexin Type 9. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 26023080 DOI: 10.1161/Atvbaha.115.305688  0.326
2015 Miao J, Ling AV, Manthena PV, Gearing ME, Graham MJ, Crooke RM, Croce KJ, Esquejo RM, Clish CB, Vicent D, Biddinger SB. Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis. Nature Communications. 6: 6498. PMID 25849138 DOI: 10.1038/Ncomms7498  0.424
2014 Kim DK, Kim YH, Hynx D, Wang Y, Yang KJ, Ryu D, Kim KS, Yoo EK, Kim JS, Koo SH, Lee IK, Chae HZ, Park J, Lee CH, Biddinger SB, et al. PKB/Akt phosphorylation of ERRγ contributes to insulin-mediated inhibition of hepatic gluconeogenesis. Diabetologia. 57: 2576-85. PMID 25205222 DOI: 10.1007/S00125-014-3366-X  0.383
2014 Kurtz CL, Peck BC, Fannin EE, Beysen C, Miao J, Landstreet SR, Ding S, Turaga V, Lund PK, Turner S, Biddinger SB, Vickers KC, Sethupathy P. MicroRNA-29 fine-tunes the expression of key FOXA2-activated lipid metabolism genes and is dysregulated in animal models of insulin resistance and diabetes. Diabetes. 63: 3141-8. PMID 24722248 DOI: 10.2337/Db13-1015  0.375
2014 Miao J, Haas JT, Manthena P, Wang Y, Zhao E, Vaitheesvaran B, Kurland IJ, Biddinger SB. Hepatic insulin receptor deficiency impairs the SREBP-2 response to feeding and statins. Journal of Lipid Research. 55: 659-67. PMID 24516236 DOI: 10.1194/Jlr.M043711  0.444
2013 Haas ME, Attie AD, Biddinger SB. The regulation of ApoB metabolism by insulin. Trends in Endocrinology and Metabolism: Tem. 24: 391-7. PMID 23721961 DOI: 10.1016/J.Tem.2013.04.001  0.39
2012 Haas JT, Miao J, Chanda D, Wang Y, Zhao E, Haas ME, Hirschey M, Vaitheesvaran B, Farese RV, Kurland IJ, Graham M, Crooke R, Foufelle F, Biddinger SB. Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression. Cell Metabolism. 15: 873-84. PMID 22682225 DOI: 10.1016/J.Cmet.2012.05.002  0.435
2011 Bezy O, Tran TT, Pihlajamäki J, Suzuki R, Emanuelli B, Winnay J, Mori MA, Haas J, Biddinger SB, Leitges M, Goldfine AB, Patti ME, King GL, Kahn CR. PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans. The Journal of Clinical Investigation. 121: 2504-17. PMID 21576825 DOI: 10.1172/Jci46045  0.495
2011 Zhou Y, Lee J, Reno CM, Sun C, Park SW, Chung J, Lee J, Fisher SJ, White MF, Biddinger SB, Ozcan U. Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction. Nature Medicine. 17: 356-65. PMID 21317886 DOI: 10.1038/Nm.2293  0.361
2011 Caron S, Verrijken A, Mertens I, Samanez CH, Mautino G, Haas JT, Duran-Sandoval D, Prawitt J, Francque S, Vallez E, Muhr-Tailleux A, Berard I, Kuipers F, Kuivenhoven JA, Biddinger SB, et al. Transcriptional activation of apolipoprotein CIII expression by glucose may contribute to diabetic dyslipidemia. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 513-9. PMID 21183731 DOI: 10.1161/Atvbaha.110.220723  0.401
2010 Suzuki R, Lee K, Jing E, Biddinger SB, McDonald JG, Montine TJ, Craft S, Kahn CR. Diabetes and insulin in regulation of brain cholesterol metabolism. Cell Metabolism. 12: 567-79. PMID 21109190 DOI: 10.1016/J.Cmet.2010.11.006  0.356
2010 Wang Y, Ziogas DC, Biddinger S, Kokkotou E. You deserve what you eat: lessons learned from the study of the melanin-concentrating hormone (MCH)-deficient mice. Gut. 59: 1625-34. PMID 20966023 DOI: 10.1136/gut.2010.210526  0.376
2010 Hirschey MD, Shimazu T, Goetzman E, Jing E, Schwer B, Lombard DB, Grueter CA, Harris C, Biddinger S, Ilkayeva OR, Stevens RD, Li Y, Saha AK, Ruderman NB, Bain JR, et al. SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature. 464: 121-5. PMID 20203611 DOI: 10.1038/Nature08778  0.354
2008 Biddinger SB, Haas JT, Yu BB, Bezy O, Jing E, Zhang W, Unterman TG, Carey MC, Kahn CR. Hepatic insulin resistance directly promotes formation of cholesterol gallstones. Nature Medicine. 14: 778-82. PMID 18587407 DOI: 10.1038/Nm1785  0.398
2008 Scapa EF, Pocai A, Wu MK, Gutierrez-Juarez R, Glenz L, Kanno K, Li H, Biddinger S, Jelicks LA, Rossetti L, Cohen DE. Regulation of energy substrate utilization and hepatic insulin sensitivity by phosphatidylcholine transfer protein/StarD2. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 2579-90. PMID 18347010 DOI: 10.1096/Fj.07-105395  0.432
2008 Biddinger SB, Hernandez-Ono A, Rask-Madsen C, Haas JT, Alemán JO, Suzuki R, Scapa EF, Agarwal C, Carey MC, Stephanopoulos G, Cohen DE, King GL, Ginsberg HN, Kahn CR. Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis. Cell Metabolism. 7: 125-34. PMID 18249172 DOI: 10.1016/J.Cmet.2007.11.013  0.458
2007 Cohen SE, Kokkotou E, Biddinger SB, Kondo T, Gebhardt R, Kratzsch J, Mantzoros CS, Kahn CR. High circulating leptin receptors with normal leptin sensitivity in liver-specific insulin receptor knock-out (LIRKO) mice. The Journal of Biological Chemistry. 282: 23672-8. PMID 17556363 DOI: 10.1074/Jbc.M704053200  0.414
2006 Biddinger SB, Miyazaki M, Boucher J, Ntambi JM, Kahn CR. Leptin suppresses stearoyl-CoA desaturase 1 by mechanisms independent of insulin and sterol regulatory element-binding protein-1c. Diabetes. 55: 2032-41. PMID 16804073 DOI: 10.2337/Db05-0742  0.447
2006 Biddinger SB, Kahn CR. From mice to men: insights into the insulin resistance syndromes. Annual Review of Physiology. 68: 123-58. PMID 16460269 DOI: 10.1146/Annurev.Physiol.68.040104.124723  0.345
2005 Biddinger SB, Almind K, Miyazaki M, Kokkotou E, Ntambi JM, Kahn CR. Effects of diet and genetic background on sterol regulatory element-binding protein-1c, stearoyl-CoA desaturase 1, and the development of the metabolic syndrome. Diabetes. 54: 1314-23. PMID 15855315 DOI: 10.2337/Diabetes.54.5.1314  0.391
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