Kelvin W. Gee - Publications

Affiliations: 
Pharmacology University of California, Irvine, Irvine, CA 
Area:
Pharmacology, Pharmaceutical Chemistry, Neuroscience Biology
Website:
https://www.faculty.uci.edu/scripts/ucifacultyprofiles/detaildept.cfm?id=2310

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Year Citation  Score
2023 Sangadi DK, Sangadi A, Placeres-Uray F, Titus DJ, Johnstone T, Hogenkamp D, Gee KW, Atkins CM. Enhancing cognitive function in chronic TBI: The Role of α7 nicotinic acetylcholine receptor modulation. Experimental Neurology. 372: 114647. PMID 38070724 DOI: 10.1016/j.expneurol.2023.114647  0.72
2020 Belelli D, Hogenkamp D, Gee KW, Lambert JJ. Realising the therapeutic potential of neuroactive steroid modulators of the GABA receptor. Neurobiology of Stress. 12: 100207. PMID 32435660 DOI: 10.1016/J.Ynstr.2019.100207  0.436
2019 Titus DJ, Johnstone T, Johnson NH, London SH, Chapalamadugu M, Hogenkamp D, Gee KW, Atkins CM. Positive allosteric modulation of the α7 nicotinic acetylcholine receptor as a treatment for cognitive deficits after traumatic brain injury. Plos One. 14: e0223180. PMID 31581202 DOI: 10.1371/Journal.Pone.0223180  0.743
2019 Johnstone TBC, McCarren HS, Spampanato J, Dudek FE, McDonough JH, Hogenkamp D, Gee KW. Enaminone Modulators of Extrasynaptic αβδ γ-Aminobutyric Acid Receptors Reverse Electrographic Status Epilepticus in the Rat After Acute Organophosphorus Poisoning. Frontiers in Pharmacology. 10: 560. PMID 31178732 DOI: 10.3389/Fphar.2019.00560  0.379
2018 Johnstone TBC, Xie JY, Qu C, Wasiak DJ, Hogenkamp DJ, Porreca F, Gee KW. Positive Allosteric Modulators of Non-Benzodiazepine γ-Aminobutyric acida Receptor Subtypes for the Treatment of Chronic Pain. Pain. PMID 30204648 DOI: 10.1097/J.Pain.0000000000001392  0.401
2018 Reddy DS, Yoshimura RF, Ramanathan G, Carver C, Johnstone TB, Hogenkamp DJ, Gee KW. Role of β-specific GABA-A receptor isoforms in the development of hippocampus kindling epileptogenesis. Epilepsy & Behavior : E&B. 82: 57-63. PMID 29587186 DOI: 10.1016/J.Yebeh.2018.02.020  0.807
2017 Yoshimura RF, Tran MB, Hogenkamp DJ, Ayala NL, Johnstone T, Dunnigan AJ, Gee TK, Gee KW. Allosteric modulation of nicotinic and GABAA receptor subtypes differentially modify autism-like behaviors in the BTBR mouse model. Neuropharmacology. PMID 28842344 DOI: 10.1016/J.Neuropharm.2017.08.029  0.791
2017 Gee KW, Olincy A, Kanner R, Johnson L, Hogenkamp D, Harris J, Tran M, Edmonds SA, Sauer W, Yoshimura R, Johnstone T, Freedman R. First in human trial of a type I positive allosteric modulator of alpha7-nicotinic acetylcholine receptors: Pharmacokinetics, safety, and evidence for neurocognitive effect of AVL-3288. Journal of Psychopharmacology (Oxford, England). 269881117691590. PMID 28196430 DOI: 10.1177/0269881117691590  0.792
2015 Dasse O, Bilcer G, Putman D, Ng R, Gee K, Stevens KE, Tran M, Johnstone T, Yoshimura RF, Koelsch G, Kelly TA. APN0417: A potent and efficacious α7 nAChR positive allosteric modulator Biochemical Pharmacology. 97: 636. DOI: 10.1016/J.Bcp.2015.08.043  0.783
2015 Titus DJ, Concepcion F, Johnstone T, Hogenkamp D, Gee KW, Atkins CM. Positive allosteric modulation of the α7 nicotinic acetylcholine receptor reverses chronic cognitive deficits after TBI Biochemical Pharmacology. 97: 635. DOI: 10.1016/J.Bcp.2015.08.041  0.766
2014 Hogenkamp DJ, Tran MB, Yoshimura RF, Johnstone TB, Kanner R, Gee KW. Pharmacological profile of a 17β-heteroaryl-substituted neuroactive steroid. Psychopharmacology. 231: 3517-24. PMID 24682501 DOI: 10.1007/S00213-014-3494-5  0.75
2014 Yoshimura RF, Tran MB, Hogenkamp DJ, Johnstone TB, Xie JY, Porreca F, Gee KW. Limited central side effects of a β-subunit subtype-selective GABAA receptor allosteric modulator. Journal of Psychopharmacology (Oxford, England). 28: 472-8. PMID 24108410 DOI: 10.1177/0269881113507643  0.812
2014 Koelsch G, Meltzer LT, Yoshimura RF, Terry AV, Callahan PM, Bilcer G, Ng J, Ng R, Gee KW, Kelly TA. P4-373: APN1125: A NOVEL A7 NICOTINIC ACETYLCHOLINE RECEPTOR PARTIAL AGONIST Alzheimer's & Dementia. 10: P925-P925. DOI: 10.1016/J.Jalz.2014.07.142  0.736
2013 Hogenkamp DJ, Ford-Hutchinson TA, Li WY, Whittemore ER, Yoshimura RF, Tran MB, Johnstone TB, Bascom GD, Rollins H, Lu L, Gee KW. Design, synthesis, and activity of a series of arylpyrid-3-ylmethanones as type I positive allosteric modulators of α7 nicotinic acetylcholine receptors. Journal of Medicinal Chemistry. 56: 8352-65. PMID 24098954 DOI: 10.1021/Jm400704G  0.806
2012 Chen S, Tusty M, Johnstone T, Hogenkamp D, Gee K, Brinton R. P2-395: Allopregnanolone analogues promote proliferation of neural progenitor cells Alzheimer's & Dementia. 8: P401-P401. DOI: 10.1016/J.Jalz.2012.05.1105  0.671
2011 Lotfipour S, Arnold MM, Hogenkamp DJ, Gee KW, Belluzzi JD, Leslie FM. The monoamine oxidase (MAO) inhibitor tranylcypromine enhances nicotine self-administration in rats through a mechanism independent of MAO inhibition. Neuropharmacology. 61: 95-104. PMID 21419142 DOI: 10.1016/J.Neuropharm.2011.03.007  0.366
2011 Johnstone TB, Gu Z, Yoshimura RF, Villegier AS, Hogenkamp DJ, Whittemore ER, Huang JC, Tran MB, Belluzzi JD, Yakel JL, Gee KW. Allosteric modulation of related ligand-gated ion channels synergistically induces long-term potentiation in the hippocampus and enhances cognition. The Journal of Pharmacology and Experimental Therapeutics. 336: 908-15. PMID 21159751 DOI: 10.1124/Jpet.110.176255  0.796
2010 Gee KW, Tran MB, Hogenkamp DJ, Johnstone TB, Bagnera RE, Yoshimura RF, Huang JC, Belluzzi JD, Whittemore ER. Limiting activity at beta1-subunit-containing GABAA receptor subtypes reduces ataxia. The Journal of Pharmacology and Experimental Therapeutics. 332: 1040-53. PMID 19940102 DOI: 10.1124/Jpet.109.161885  0.737
2010 HOGENKAMP DJ, TAHIR SH, HAWKINSON JE, UPASANI RB, ALAUDDIN M, KIMBROUGH CL, ACOSTA-BURRUEL M, WHITTEMORE ER, WOODWARD RM, LAN NC, GEE KW, BOLGER MB. ChemInform Abstract: Synthesis and in vitro Activity of 3β-Substituted-3α- hydroxypregnan-20-ones: Allosteric Modulators of the GABAA Receptor. Cheminform. 28: no-no. DOI: 10.1002/chin.199717196  0.323
2009 Gee K, Hogenkamp D, Johnstone T. Dual allosteric modulators of neuronal nicotinic-acetylcholine and GABAA receptors Biochemical Pharmacology. 78: 913-914. DOI: 10.1016/J.Bcp.2009.06.065  0.757
2007 Yoshimura RF, Hogenkamp DJ, Li WY, Tran MB, Belluzzi JD, Whittemore ER, Leslie FM, Gee KW. Negative allosteric modulation of nicotinic acetylcholine receptors blocks nicotine self-administration in rats. The Journal of Pharmacology and Experimental Therapeutics. 323: 907-15. PMID 17873105 DOI: 10.1124/Jpet.107.128751  0.777
2007 Hogenkamp DJ, Johnstone TB, Huang JC, Li WY, Tran M, Whittemore ER, Bagnera RE, Gee KW. Enaminone amides as novel orally active GABAA receptor modulators. Journal of Medicinal Chemistry. 50: 3369-79. PMID 17571865 DOI: 10.1021/Jm070083V  0.771
2007 Ng HJ, Whittemore ER, Tran MB, Hogenkamp DJ, Broide RS, Johnstone TB, Zheng L, Stevens KE, Gee KW. Nootropic alpha7 nicotinic receptor allosteric modulator derived from GABAA receptor modulators. Proceedings of the National Academy of Sciences of the United States of America. 104: 8059-64. PMID 17470817 DOI: 10.1073/Pnas.0701321104  0.805
2006 Wang J, Hogenkamp DJ, Tran M, Li WY, Yoshimura RF, Johnstone TB, Shen WC, Gee KW. Reversible lipidization for the oral delivery of leu-enkephalin. Journal of Drug Targeting. 14: 127-36. PMID 16753826 DOI: 10.1080/10611860600648221  0.75
2004 Johnstone TB, Hogenkamp DJ, Coyne L, Su J, Halliwell RF, Tran MB, Yoshimura RF, Li WY, Wang J, Gee KW. Modifying quinolone antibiotics yields new anxiolytics. Nature Medicine. 10: 31-2. PMID 14647497 DOI: 10.1038/Nm967  0.787
2001 Vanover KE, Hogenkamp DJ, Lan NC, Gee KW, Carter RB. Behavioral characterization of Co 134444 (3alpha-hydroxy-21-(1'-imidazolyl)-3beta-methoxymethyl-5alpha- pregnan-20-one), a novel sedative-hypnotic neuroactive steroid. Psychopharmacology. 155: 285-91. PMID 11432691 DOI: 10.1007/S002130100695  0.328
1999 Vanover KE, Suruki M, Robledo S, Huber M, Wieland S, Lan NC, Gee KW, Wood PL, Carter RB. Positive allosteric modulators of the GABA(A) receptor: differential interaction of benzodiazepines and neuroactive steroids with ethanol. Psychopharmacology. 141: 77-82. PMID 9952068 DOI: 10.1007/S002130050809  0.384
1997 Wieland S, Belluzzi J, Hawkinson JE, Hogenkamp D, Upasani R, Stein L, Wood PL, Gee KW, Lan NC. Anxiolytic and anticonvulsant activity of a synthetic neuroactive steroid Co 3-0593. Psychopharmacology. 134: 46-54. PMID 9399366 DOI: 10.1007/S002130050424  0.383
1997 Carter RB, Wood PL, Wieland S, Hawkinson JE, Belelli D, Lambert JJ, White HS, Wolf HH, Mirsadeghi S, Tahir SH, Bolger MB, Lan NC, Gee KW. Characterization of the anticonvulsant properties of ganaxolone (CCD 1042; 3alpha-hydroxy-3beta-methyl-5alpha-pregnan-20-one), a selective, high-affinity, steroid modulator of the gamma-aminobutyric acid(A) receptor. The Journal of Pharmacology and Experimental Therapeutics. 280: 1284-95. PMID 9067315  0.334
1997 Hogenkamp DJ, Tahir SH, Hawkinson JE, Upasani RB, Alauddin M, Kimbrough CL, Acosta-Burruel M, Whittemore ER, Woodward RM, Lan NC, Gee KW, Bolger MB. Synthesis and in vitro activity of 3 beta-substituted-3 alpha-hydroxypregnan-20-ones: allosteric modulators of the GABAA receptor. Journal of Medicinal Chemistry. 40: 61-72. PMID 9016329 DOI: 10.1021/Jm960021X  0.378
1996 Belelli D, Lambert JJ, Peters JA, Gee KW, Lan NC. Modulation of human recombinant GABAA receptors by pregnanediols. Neuropharmacology. 35: 1223-31. PMID 9014137 DOI: 10.1016/S0028-3908(96)00066-4  0.374
1996 Xue BG, Friend JM, Gee KW. Loreclezole modulates [35S]t-butylbicyclophosphorothionate and [3H]flunitrazepam binding via a distinct site on the GABAA receptor complex European Journal of Pharmacology. 300: 125-130. PMID 8741177 DOI: 10.1016/0014-2999(95)00856-X  0.488
1995 Gee KW, McCauley LD, Lan NC. A putative receptor for neurosteroids on the GABA(A) receptor complex: The pharmacological properties and therapeutic potential of epalons Critical Reviews in Neurobiology. 9: 207-227. PMID 8581984  0.347
1995 McCauley LD, Gee KW. Influence of the estrus cycle on the discrimination of apparent neuroactive steroid site subtypes on the γ-aminobutyric acid(A) receptor complex in the rat Journal of Pharmacology and Experimental Therapeutics. 275: 1412-1417. PMID 8531110  0.315
1995 Lan NC, Chen JS, Johnson D, Gee KW. Differential effects of 4′-chlorodiazepam on expressed human GABAA receptors Journal of Neurochemistry. 64: 684-688. PMID 7830061 DOI: 10.1046/J.1471-4159.1995.64020684.X  0.44
1995 McCauley LD, Park CH, Lan NC, Tomich JM, Shively JE, Gee KW. Benzodiazepines and peptides stimulate pregnenolone synthesis in brain mitochondria European Journal of Pharmacology. 276: 145-153. PMID 7781684 DOI: 10.1016/0014-2999(95)00036-K  0.371
1995 Wang MD, Wahlström G, Gee KW, Bäckström T. Potency of lipid and protein formulation of 5 alpha-pregnanolone at induction of anaesthesia and the corresponding regional brain distribution. British Journal of Anaesthesia. 74: 553-7. PMID 7772431 DOI: 10.1093/Bja/74.5.553  0.321
1994 Hawkinson JE, Kimbrough CL, McCauley LD, Bolger MB, Lan NC, Gee KW. The neuroactive steroid 3 alpha-hydroxy-5 beta-pregnan-20-one is a two-component modulator of ligand binding to the GABAA receptor. European Journal of Pharmacology. 269: 157-63. PMID 7851492 DOI: 10.1016/0922-4106(94)90082-5  0.388
1994 Lan NC, Gee KW. Neuroactive steroid actions at the GABA(A) receptor Hormones and Behavior. 28: 537-544. PMID 7729823 DOI: 10.1006/Hbeh.1994.1052  0.507
1994 McCauley LD, Gee KW. Detection and Characterization of Epalon Receptors: Novel Recognition Sites for Neuroactive Steroids That Modulate the GABAA Receptor Complex Methods in Neurosciences. 22: 211-225. DOI: 10.1016/B978-0-12-185292-4.50019-X  0.402
1993 Finn DA, Gee KW. A comparison of Ro 16-6028 with benzodiazepine receptor 'full agonists' on GABAA receptor function. European Journal of Pharmacology. 247: 233-7. PMID 7905829 DOI: 10.1016/0922-4106(93)90190-K  0.458
1992 Cadoni C, Gee KW. Complex interactions between the steroid derivative RU 5135 and the GABAA-receptor complex European Journal of Pharmacology: Molecular Pharmacology. 227: 147-151. PMID 1330646 DOI: 10.1016/0922-4106(92)90122-C  0.465
1992 McNeil RG, Gee KW, Bolger MB, Lan NC, Wieland S, Belelli D, Purdy RH, Paul SM. Neuroactive steroids that act at GABA(A) receptors Drug News and Perspectives. 5: 145-152.  0.33
1991 Wieland S, Lan NC, Mirasedeghi S, Gee KW. Anxiolytic activity of the progesterone metabolite 5α-pregnan-3α-ol-20-one Brain Research. 565: 263-268. PMID 1688192 DOI: 10.1016/0006-8993(91)91658-N  0.318
1991 Lan NC, Bolger MB, Gee KW. Identification and characterization of a pregnane steroid recognition site that is functionally coupled to an expressed GABAA receptor Neurochemical Research. 16: 347-356. PMID 1664061 DOI: 10.1007/Bf00966098  0.376
1991 Lan NC, Gee KW, Bolger MB, Chen JS. Differential responses of expressed recombinant human γ-aminobutyric acidA receptors to neurosteroids Journal of Neurochemistry. 57: 1818-1821. PMID 1655982 DOI: 10.1111/J.1471-4159.1991.Tb06388.X  0.459
1990 Belelli D, Lan NC, Gee KW. Anticonvulsant steroids and the GABA/benzodiazepine receptor-chloride ionophore complex. Neuroscience and Biobehavioral Reviews. 14: 315-22. PMID 2172879 DOI: 10.1016/S0149-7634(05)80041-7  0.429
1990 Lan NC, Chen JS, Belelli D, Pritchett DB, Seeburg PH, Gee KW. A steroid recognition site is functionally coupled to an expressed GABA(A)-benzodiazepine receptor. European Journal of Pharmacology. 188: 403-6. PMID 2164942 DOI: 10.1016/0922-4106(90)90201-8  0.452
1990 Belelli D, McCauley L, Gee KW. Heterotropic cooperativity between putative recognition sites for progesterone metabolites and the atypical benzodiazepine Ro 5-4864. Journal of Neurochemistry. 55: 83-7. PMID 2113084 DOI: 10.1111/J.1471-4159.1990.Tb08824.X  0.379
1990 McCauley L, Belelli D, Gee KW. Benzodiazepine receptor subtypes and receptor reserve capacity in rat brain European Journal of Pharmacology. 183: 2151. DOI: 10.1016/0014-2999(90)93675-G  0.405
1990 Belelli D, McCauley L, Lan N, Bolger MB, Johnson D, Gee KW. Heterotropic cooperativity between recognition sites for steroids and 4'-chlorodiazepam (Ro5 4864) on the GABA/benzodiazepine receptor complex European Journal of Pharmacology. 183: 2024. DOI: 10.1016/0014-2999(90)92383-T  0.413
1989 Belelli D, Bolger MB, Gee KW. Anticonvulsant profile of the progesterone metabolite 5 alpha-pregnan-3 alpha-ol-20-one. European Journal of Pharmacology. 166: 325-9. PMID 2792198 DOI: 10.1016/0014-2999(89)90077-0  0.409
1989 Ali SF, Newport GD, Scallet AC, Gee KW, Paule MG, Brown RM, Slikker W. Effects of chronic delta-9-tetrahydrocannabinol (THC) administration on neurotransmitter concentrations and receptor binding in the rat brain. Neurotoxicology. 10: 491-500. PMID 2576303  0.331
1989 Belelli D, Gee KW. 5 alpha-pregnan-3 alpha,20 alpha-diol behaves like a partial agonist in the modulation of GABA-stimulated chloride ion uptake by synaptoneurosomes. European Journal of Pharmacology. 167: 173-6. PMID 2550257 DOI: 10.1016/0014-2999(89)90760-7  0.348
1989 Gee KW, Joy DS, Belelli D. Complex interactions between pregnenolone sulfate and the t-butylbicyclophosphorothionate-labeled chloride ionophore in rat brain. Brain Research. 482: 169-73. PMID 2539882 DOI: 10.1016/0006-8993(89)90556-8  0.408
1988 Gee KW. Steroid modulation of the GABA/benzodiazepine receptor-linked chloride lonophore Molecular Neurobiology. 2: 291-317. PMID 2855977 DOI: 10.1007/Bf02935636  0.48
1988 Gee KW, Bolger MB, Brinton RE, Coirini H, McEwen BS. Steroid modulation of the chloride ionophore in rat brain: Structure-activity requirements, regional dependence and mechanism of action Journal of Pharmacology and Experimental Therapeutics. 246: 803-812. PMID 2841455  0.406
1988 Gee KW, Brinton RE, McEwen BS. Regional distribution of a Ro5 4864 binding site that is functionally coupled to the γ-aminobutyric acid/benzodiazepine receptor complex in rat brain Journal of Pharmacology and Experimental Therapeutics. 244: 379-383. PMID 2826772  0.343
1987 Gee KW, Chang WC, Brinton RE, McEwen BS. GABA-dependent modulation of the Cl- ionophore by steroids in rat brain European Journal of Pharmacology. 136: 419-423. PMID 3609126 DOI: 10.1016/0014-2999(87)90317-7  0.481
1986 Gee KW, Lawrence LJ, Yamamura HI. Modulation of the chloride ionophore by benzodiazepine receptor ligands: influence of gamma-aminobutyric acid and ligand efficacy. Molecular Pharmacology. 30: 218-25. PMID 3018479  0.332
1985 Lawrence LJ, Palmer CJ, Gee KW, Wang X, Yamamura HI, Casida JE. t-[3H]butylbicycloorthobenzoate: new radioligand probe for the gamma-aminobutyric acid-regulated chloride ionophore. Journal of Neurochemistry. 45: 798-804. PMID 2993514 DOI: 10.1111/J.1471-4159.1985.Tb04063.X  0.322
1985 Gee KW, Lawrence LJ, Yamamura HI. Differential modulation of 35S-t-butylbicyclophosphorothionate (35S-TBPS) binding in rat brain by benzodiazepine (BZ) receptor ligands: Effect of GABA and ligand efficacy Federation Proceedings. 44.  0.308
1984 Brinton RE, Gee KW, Wamsley JK, Davis TP, Yamamura HI. Regional distribution of putative vasopressin receptors in rat brain and pituitary by quantitative autoradiography. Proceedings of the National Academy of Sciences of the United States of America. 81: 7248-52. PMID 6095279 DOI: 10.1073/Pnas.81.22.7248  0.306
1984 Lawrence LJ, Gee KW, Yamamura HI. Benzodiazepine anticonvulsant action: gamma-aminobutyric acid-dependent modulation of the chloride ionophore. Biochemical and Biophysical Research Communications. 123: 1130-7. PMID 6091648 DOI: 10.1016/S0006-291X(84)80250-8  0.451
1984 Gee KW, Yamamura SH, Roeske WR, Yamamura HI. Benzodiazepine receptor heterogeneity: possible molecular basis and functional significance. Federation Proceedings. 43: 2767-72. PMID 6090222  0.317
1983 Gee KW, Killam EK, Hollinger MA. Effects of haloperidol-induced dopamine receptor supersensitivity on kindled seizure development. The Journal of Pharmacology and Experimental Therapeutics. 225: 70-6. PMID 6834278  0.645
1983 Wamsley JK, Gee KW, Yamamura HI. Comparison of the distribution of convulsant/barbiturate and benzodiazepine receptors using light microscopic autoradiography. Life Sciences. 33: 2321-9. PMID 6316061 DOI: 10.1016/0024-3205(83)90266-7  0.437
1983 Gee KW, Yamamura HI. Photoaffinity labeling of benzodiazepine receptors in rat brain with flunitrazepam alters the affinity of benzodiazepine receptor agonist but not antagonist binding. Journal of Neurochemistry. 41: 1407-13. PMID 6311986 DOI: 10.1111/J.1471-4159.1983.Tb00839.X  0.364
1983 Ehlert FJ, Roeske WR, Gee KW, Yamamura HI. An allosteric model for benzodiazepine receptor function Biochemical Pharmacology. 32: 2375-2383. PMID 6311215 DOI: 10.1016/0006-2952(83)90679-2  0.458
1983 Mosberg HI, Hurst R, Hruby VJ, Gee K, Yamamura HI, Galligan JJ, Burks TF. Bis-penicillamine enkephalins possess highly improved specificity toward delta opioid receptors. Proceedings of the National Academy of Sciences of the United States of America. 80: 5871-4. PMID 6310598 DOI: 10.1073/Pnas.80.19.5871  0.342
1983 Mosberg HI, Hurst R, Hruby VJ, Galligan JJ, Burks TF, Gee K, Yamamura HI. Conformationally constrained cyclic enkephalin analogs with pronounced delta opioid receptor agonist selectivity. Life Sciences. 32: 2565-9. PMID 6304440 DOI: 10.1016/0024-3205(83)90239-4  0.381
1983 Gee KW, Brinton RE, Yamamura HI. PK 8165 and PK 9084, two quinoline derivatives with anxiolytic properties, antagonize the anticonvulsant effects of diazepam Brain Research. 264: 168-172. PMID 6303496 DOI: 10.1016/0006-8993(83)91138-1  0.447
1983 Yamamura HI, Gee KW, Brinton RE, Davis TP, Hadley M, Wamsley JK. Light microscopic autoradiographic visualization of [3H]-arginine vasopressin binding sites in rat brain. Life Sciences. 32: 1919-24. PMID 6300592 DOI: 10.1016/0024-3205(83)90072-3  0.308
1983 Gee KW, Ehlert FJ, Yamamura HI. Differential effect of γ-aminobutyric acid on benzodiazepine receptor subtypes labeled by [3H]propyl β-carboline-3-carboxylate in rat brain Journal of Pharmacology and Experimental Therapeutics. 225: 132-137. PMID 6300371  0.303
1983 Gee KW, Brinton RE, Yamamura HI. CL 218872 antagonism of diazepam induced loss of righting reflex: Evidence for partial agonistic activity at the benzodiazepine receptor Life Sciences. 32: 1037-1040. PMID 6298552 DOI: 10.1016/0024-3205(83)90936-0  0.452
1983 Gee KW, Yamamura HI. Selective anxiolytics: are the actions related to partial "agonist" activity or a preferential affinity for benzodiazepine receptor subtypes? Advances in Biochemical Psychopharmacology. 38: 1-9. PMID 6142598  0.357
1983 Brinton RE, Gee KW, Yamamura HI. CL 218872, PK 8165 and PK 9084: Selective anxiolytics that may act as partial agonist at the benzodiazepine receptor Federation Proceedings. 42.  0.318
1982 Gee KW, Yamamura HI. Regional heterogeneity of benzodiazepine receptors at 37°C: An in vitro study in various regions of the rat brain Life Sciences. 31: 1939-1945. PMID 6294423 DOI: 10.1016/0024-3205(82)90032-7  0.423
1982 Gee KW, Yamamura HI. Differentiation of benzodiazepine receptor agonist and antagonist: Sparing of [3H]benzodiazepine antagonist binding following the photolabelling of benzodiazepine receptors European Journal of Pharmacology. 82: 239-241. PMID 6290239 DOI: 10.1016/0014-2999(82)90521-0  0.432
1982 Gee KW, Ehlert FJ, Yamamura HI. The influence of temperature and gamma-aminobutyric acid on benzodiazepine receptor subtypes in the hippocampus of the rat Biochemical and Biophysical Research Communications. 106: 1134-1140. PMID 6288041 DOI: 10.1016/0006-291X(82)91230-X  0.405
1982 Morelli M, Gee KW, Yamamura HI. The effect of GABA on in vitro binding of two novel non-benzodiazepines, PK 8165 and CGS 8216, to benzodiazepine receptors in the rat brain Life Sciences. 31: 77-81. PMID 6287150 DOI: 10.1016/0024-3205(82)90403-9  0.454
1982 Gee KW, Yamamura HI. A novel pyrazoloquinoline that interacts with brain benzodiazepine receptors: Characterization of some in vitro and in vivo properties of CGS 9896 Life Sciences. 30: 2245-2252. PMID 6287145 DOI: 10.1016/0024-3205(82)90251-X  0.439
1982 Mosberg HI, Hurst R, Hruby VJ, Galligan JJ, Burks TF, Gee K, Yamamura HI. [D-Pen2, L-Cys5]enkephalinamide and[D-Pen2, D-Cys5] enkephalinamide, conformationally constrained cyclic enkephalinamide analogs with delta receptor specificity. Biochemical and Biophysical Research Communications. 106: 506-12. PMID 6285922 DOI: 10.1016/0006-291X(82)91139-1  0.322
1982 Gee KW, Morelli M, Yamamura HI. The effect of temperature on CL 218872 and propyl beta-carboline-3-carboxylate inhibition of [3H]-flunitrazepam binding in rat brain Biochemical and Biophysical Research Communications. 105: 1532-1537. PMID 6125147 DOI: 10.1016/0006-291X(82)90962-7  0.397
1982 Gee KW, Horst WD, O'Brien R, Yamamura HI. High affinity inhibition of [3H]-Flunitrazepam binding to brain benzodiazepine receptors by CGS 9896, a novel pyrazoloquinoline Biochemical and Biophysical Research Communications. 105: 457-461. PMID 6124246 DOI: 10.1016/0006-291X(82)91456-5  0.338
1981 Gee KW, Hollinger MA, Killam EK. Effect of seizures kindled by subconvulsant doses of pentylenetetrazol on dopamine receptor binding and dopamine-sensitive adenylate cyclase in the rat. Experimental Neurology. 74: 265-75. PMID 6269870 DOI: 10.1016/0014-4886(81)90164-3  0.677
1981 Gee KW, Killam EK, Hollinger MA. The relationship of dopamine receptors to seizure development: Effects of haloperidol-induced supersensitivity Epilepsia. 22: 227.  0.635
1980 Gee KW, Killam EK, Hollinger MA, Giri SN. Effect of anygdaloid kindling on dopamine-sensitive adenylate cyclase activity in rat brain. Experimental Neurology. 70: 192-9. PMID 7418769 DOI: 10.1016/0014-4886(80)90018-7  0.638
1980 Gee KW, Killam EK, Hollinger MA, Giri SN. Alterations in dopamine-sensitive adenylate cyclase in the rat brain following amygdaloid kindling Pharmacologist. 22: No. 759.  0.608
1980 Gee KW, Killam EK, Hollinger MA. The effects of chronic pentylenetetrazol on dopamine receptor binding in the rat brain Federation Proceedings. 39: 3895.  0.657
1979 Gee KW, Hollinger MA, Bowyer JF, Killam EK. Modification of dopaminergic receptor sensitivity in rat brain after amygdaloid kindling. Experimental Neurology. 66: 771-7. PMID 488251 DOI: 10.1016/0014-4886(79)90220-6  0.695
Low-probability matches (unlikely to be authored by this person)
1985 Akiyama K, Gee KW, Mosberg HI, Hruby VJ, Yamamura HI. Characterization of [3H][2-D-penicillamine, 5-D-penicillamine]-enkephalin binding to delta opiate receptors in the rat brain and neuroblastoma--glioma hybrid cell line (NG 108-15). Proceedings of the National Academy of Sciences of the United States of America. 82: 2543-7. PMID 2986120 DOI: 10.1073/Pnas.82.8.2543  0.299
1991 Gee KW, Lan NC. γ-Aminobutyric acidA receptor complexes in rat frontal cortex and spinal cord show differential responses to steroid modulation Molecular Pharmacology. 40: 995-999. PMID 1661843  0.297
1983 Mosberg HI, Hurst R, Hruby VJ, Gee K, Akiyama K, Yamamura HI, Galligan JJ, Burks TF. Cyclic penicillamine containing enkephalin analogs display profound delta receptor selectivities. Life Sciences. 33: 447-50. PMID 6319901 DOI: 10.1016/0024-3205(83)90538-6  0.297
1996 Park CH, Carboni E, Wood PL, Gee KW. Characterization of peripheral benzodiazepine type sites in a cultured murine BV-2 microglial cell line Glia. 16: 65-70. PMID 8787774 DOI: 10.1002/(Sici)1098-1136(199601)16:1<65::Aid-Glia7>3.0.Co;2-A  0.294
1996 Hawkinson JE, Drewe JA, Kimbrough CL, Chen JS, Hogenkamp DJ, Lan NC, Gee KW, Shen KZ, Whittemore ER, Woodward RM. 3 alpha-Hydroxy-3 beta-trifluoromethyl-5 alpha-pregnan-20-one (Co 2-1970): a partial agonist at the neuroactive steroid site of the gamma-aminobutyric acidA receptor. Molecular Pharmacology. 49: 897-906. PMID 8622640  0.294
1997 Xue BG, Whittemore ER, Park CH, Woodward RM, Lan NC, Gee KW. Partial agonism by 3α,21-dihydroxy-5β-pregnan-20-one at the γ- aminobutyric acid(A) receptor neurosteroid site Journal of Pharmacology and Experimental Therapeutics. 281: 1095-1101. PMID 9190841  0.285
1984 Brinton RE, Wamsley JK, Gee KW, Wan YP, Yamamura HI. [3H]oxytocin binding sites in the rat brain demonstrated by quantitative light microscopic autoradiography. European Journal of Pharmacology. 102: 365-7. PMID 6090165 DOI: 10.1016/0014-2999(84)90270-X  0.279
1982 Gee KW, Horst WD, O'Brien R, Yamamura HI. CGS 9896 and CGS 8216: Two potent inhibitors of benzodiazepine (BZD) receptor binding in the rat brain Federation Proceedings. 41.  0.274
1990 Lan NC, Chen JS, Belelli D, Pritchett DB, Seeburg PH, Gee KW. A steroid recognition site is functionally coupled to expressed GABA(A)/benzo-diazepine receptors European Journal of Pharmacology. 183: 2023. DOI: 10.1016/0014-2999(90)92382-S  0.274
1996 Gee KW. Epalons as anticonvulsants: Actions mediated by the GABAA receptor complex Proceedings of the Western Pharmacology Society. 39: 55. PMID 8895969  0.271
1983 Gee KW, Wamsley JK, Yamamura HI. Light microscopic autoradiographic identification of picrotoxin/barbiturate binding sites in rat brain with [35S]t-butyl-bicyclophosphathionate European Journal of Pharmacology. 89: 323-324. PMID 6307715 DOI: 10.1016/0014-2999(83)90516-2  0.268
1993 Finn DA, Gee KW. The influence of estrus cycle on neurosteroid potency at the gamma-aminobutyric acidA receptor complex. The Journal of Pharmacology and Experimental Therapeutics. 265: 1374-9. PMID 8389864  0.236
1992 McCauley LD, Lan NC, Tomich JM, Shively JE, Gee KW. Peripheral-type benzodiazepine receptors and the regulation of steroidogenesis in rat brain mitochondria Advances in Biochemical Psychopharmacology. 47: 143-147. PMID 1324568  0.233
1992 Gee KW, Lan NC, Bolger MB, Wieland S, Belelli D, Chen JS. Pharmacology of a GABAA receptor coupled steroid recognition site. Advances in Biochemical Psychopharmacology. 47: 111-7. PMID 1354914  0.23
1995 McCauley LD, Liu V, Chen JS, Hawkinson JE, Lan NC, Gee KW. Selective actions of certain neuroactive pregnanediols at the gamma-aminobutyric acid type A receptor complex in rat brain. Molecular Pharmacology. 47: 354-62. PMID 7870044  0.204
1996 Carboni E, Wieland S, Lan NC, Gee KW. Anxiolytic properties of endogenously occurring pregnanediols in two rodent models of anxiety Psychopharmacology. 126: 173-178. PMID 8856837 DOI: 10.1007/Bf02246353  0.199
1987 Gee KW. Phenylquinolines PK 8165 and PK 9084 allosterically modulate [35S]t-butylbicyclophosphorothionate binding to a chloride ionophore in rat brain via a novel Ro5 4864 binding site Journal of Pharmacology and Experimental Therapeutics. 240: 747-753. PMID 3031273  0.183
1990 Bäckström T, Gee KW, Lan N, Sörensen M, Wahlström G. Steroids in relation to epilepsy and anaesthesia Ciba Foundation Symposium. 153: 225-230; discussion . PMID 2292214  0.177
1994 Finn DA, Gee KW. The estrus cycle, sensitivity to convulsants and the anticonvulsant effect of a neuroactive steroid. The Journal of Pharmacology and Experimental Therapeutics. 271: 164-70. PMID 7965710  0.175
1985 Yamamura HI, Gehlert DR, Gee KW, Wamsley JK, Horst WD, Roeske WR. Specific high-affinity [3H]Ro5-4864 Ro5-4864 benzodiazepine binding sites in the brain and periphery. Progress in Clinical and Biological Research. 192: 187-96. PMID 3001751  0.153
1997 Edgar DM, Seidel WF, Gee KW, Lan NC, Field G, Xia H, Hawkinson JE, Wieland S, Carter RB, Wood PL. CCD-3693: an orally bioavailable analog of the endogenous neuroactive steroid, pregnanolone, demonstrates potent sedative hypnotic actions in the rat. The Journal of Pharmacology and Experimental Therapeutics. 282: 420-9. PMID 9223583  0.152
1985 Yamamura HI, Akiyama K, Gee KW. Tritium (D-pen2,D-pen5)enkephalin, a highly selective radioligand for the identification and characterization of the delta opioid receptor Federation Proceedings. 44.  0.144
1987 Syapin PJ, Gee KW, Alkana RL. Rol5-4513 differentially affects ethanol-induced hypnosis and hypothermia Brain Research Bulletin. 19: 603-605. PMID 3690369 DOI: 10.1016/0361-9230(87)90078-5  0.129
1999 Vanover KE, Edgar DM, Seidel WF, Hogenkamp DJ, Fick DB, Lan NC, Gee KW, Carter RB. Response-rate suppression in operant paradigm as predictor of soporific potency in rats and identification of three novel sedative-hypnotic neuroactive steroids. The Journal of Pharmacology and Experimental Therapeutics. 291: 1317-23. PMID 10565857  0.124
1997 Lan NC, Gee KW. Epalons as promising therapeutic agents Drug News and Perspectives. 10: 604-611.  0.115
1985 Lawrence LJ, Gee KW, Yamamura HI. Interactions of pyrethroid insecticides with chloride ionophore-associated binding sites. Neurotoxicology. 6: 87-98. PMID 2410833  0.098
1996 Schulz H, Jobert M, Gee KW, Ashbrook DW. Soporific effect of the neurosteroid pregnanolone in relation to the substance's plasma level: A pilot study Neuropsychobiology. 34: 106-112. PMID 8904740  0.09
1977 Gee KW, Navarro G. Comparison of the effects of phenoxybenzamine and morphine on the isolated guinea pig ileum Proceedings of the Western Pharmacology Society. 389-391. PMID 896845  0.057
2013 Loh AH, Gee KW, Chua JH. Diagnostic accuracy of preoperative alpha-fetoprotein as an ovarian tumor marker in children and adolescents: not as good as we thought? Pediatric Surgery International. 29: 709-13. PMID 23653236 DOI: 10.1007/s00383-013-3316-6  0.053
2003 Gee KW, Mueller S. Advancing the pavement preservation movement: Federal highway administration cultivates partnerships Tr News. 16-21.  0.022
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