| Year |
Citation |
Score |
| 2023 |
Duncan GJ, Ingram SD, Emberley K, Hill J, Cordano C, Abdelhak A, McCane M, Jabassini N, Ananth K, Ferrara SJ, Stedelin B, Sivyer B, Aicher SA, Scanlan T, Watkins TA, et al. Remyelination protects neurons from DLK-mediated neurodegeneration. Biorxiv : the Preprint Server For Biology. PMID 37873342 DOI: 10.1101/2023.09.30.560267 |
0.695 |
|
| 2021 |
Ferrara SJ, Chaudhary P, DeBell MJ, Marracci G, Miller H, Calkins E, Pocius E, Napier BA, Emery B, Bourdette D, Scanlan TS. TREM2 is thyroid hormone regulated making the TREM2 pathway druggable with ligands for thyroid hormone receptor. Cell Chemical Biology. PMID 34375614 DOI: 10.1016/j.chembiol.2021.07.014 |
0.783 |
|
| 2021 |
Ferrara SJ, Chaudhary P, DeBell MJ, Marracci G, Miller H, Calkins E, Pocius E, Napier BA, Emery B, Bourdette D, Scanlan TS. is thyroid hormone regulated making the TREM2 pathway druggable with ligands for thyroid hormone receptor. Biorxiv : the Preprint Server For Biology. PMID 33532772 DOI: 10.1101/2021.01.25.428149 |
0.781 |
|
| 2020 |
Ferrara SJ, Scanlan TS. A CNS-Targeting Prodrug Strategy for Nuclear Receptor Modulators. Journal of Medicinal Chemistry. 63: 9742-9751. PMID 32787092 DOI: 10.1021/Acs.Jmedchem.0C00868 |
0.755 |
|
| 2020 |
Hartley MD, Shokat MD, DeBell MJ, Banerji T, Kirkemo LL, Scanlan TS. Pharmacological Complementation Remedies an Inborn Error of Lipid Metabolism. Cell Chemical Biology. PMID 32169163 DOI: 10.1016/J.Chembiol.2020.02.008 |
0.343 |
|
| 2019 |
Hartley MD, Banerji T, Tagge IJ, Kirkemo LL, Chaudhary P, Calkins E, Galipeau D, Shokat MD, DeBell MJ, Van Leuven S, Miller H, Marracci G, Pocius E, Banerji T, Ferrara SJ, ... ... Scanlan TS, et al. Myelin repair stimulated by CNS-selective thyroid hormone action. Jci Insight. 4. PMID 30996143 DOI: 10.1172/Jci.Insight.126329 |
0.736 |
|
| 2019 |
Hirose K, Payumo AY, Cutie S, Hoang A, Zhang H, Guyot R, Lunn D, Bigley RB, Yu H, Wang J, Smith M, Gillett E, Muroy SE, Schmid T, Wilson E, ... ... Scanlan TS, et al. Evidence for hormonal control of heart regenerative capacity during endothermy acquisition. Science (New York, N.Y.). PMID 30846611 DOI: 10.1126/Science.Aar2038 |
0.368 |
|
| 2019 |
Chattergoon NN, Louey S, Scanlan T, Lindgren I, Giraud GD, Thornburg KL. Thyroid hormone receptor function in maturing ovine cardiomyocytes. The Journal of Physiology. PMID 30770568 DOI: 10.1113/JP276874 |
0.379 |
|
| 2019 |
Meinig JM, Ferrara SJ, Banerji T, Banerji T, Sanford-Crane HS, Bourdette D, Scanlan TS. Structure-Activity Relationships of Central Nervous System Penetration by Fatty Acid Amide Hydrolase (FAAH)-Targeted Thyromimetic Prodrugs. Acs Medicinal Chemistry Letters. 10: 111-116. PMID 30655956 DOI: 10.1021/Acsmedchemlett.8B00501 |
0.758 |
|
| 2018 |
Smith TJ, Scanlan TS, Fernando R. Response to Letter: Elevated serum tetrac in Graves' disease: potential pathogenic role in thyroid-associated ophthalmopathy. The Journal of Clinical Endocrinology and Metabolism. PMID 30566642 DOI: 10.1210/Jc.2018-02282 |
0.321 |
|
| 2018 |
Devereaux J, Ferrara SJ, Scanlan TS. Quantification of Thyromimetic Sobetirome Concentration in Biological Tissue Samples. Methods in Molecular Biology (Clifton, N.J.). 1801: 193-206. PMID 29892826 DOI: 10.1007/978-1-4939-7902-8_16 |
0.756 |
|
| 2018 |
Ferrara SJ, Bourdette D, Scanlan TS. Hypothalamic-Pituitary-Thyroid Axis Perturbations in Male Mice by CNS-Penetrating Thyromimetics. Endocrinology. PMID 29846550 DOI: 10.1210/En.2018-00065 |
0.787 |
|
| 2018 |
Bárez-López S, Hartley MD, Grijota-Martínez C, Scanlan TS, Guadaño-Ferraz A. Sobetirome and its Amide Prodrug Sob-AM2 Exert Thyromimetic Actions in Mct8-Deficient Brain. Thyroid : Official Journal of the American Thyroid Association. PMID 29845892 DOI: 10.1089/Thy.2018.0008 |
0.33 |
|
| 2018 |
Aguayo-Mazzucato C, Lee TB, Matzko M, DiIenno A, Rezanejad H, Ramadoss P, Scanlan T, Zavacki AM, Larsen PR, Hollenberg A, Colton C, Sharma A, Bonner-Weir S. TInduces Both Markers of Maturation and Aging in Pancreatic β-Cells. Diabetes. PMID 29625991 DOI: 10.2337/Db18-0030 |
0.354 |
|
| 2017 |
Meinig JM, Ferrara SJ, Banerji T, Banerji T, Sanford-Crane HS, Bourdette D, Scanlan TS. Targeting fatty-acid amide hydrolase with prodrugs for CNS-selective therapy. Acs Chemical Neuroscience. PMID 28756656 DOI: 10.1021/Acschemneuro.7B00239 |
0.726 |
|
| 2017 |
Ma H, Yang F, Butler MR, Belcher J, Redmond TM, Placzek AT, Scanlan TS, Ding XQ. Inhibition of thyroid hormone receptor locally in the retina is a therapeutic strategy for retinal degeneration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28428265 DOI: 10.1096/Fj.201601166Rr |
0.386 |
|
| 2017 |
Ferrara SJ, Meinig JM, Placzek AT, Banerji T, McTigue P, Hartley MD, Sanford-Crane HS, Banerji T, Bourdette D, Scanlan TS. Ester-to-amide rearrangement of ethanolamine-derived prodrugs of sobetirome with increased blood-brain barrier penetration. Bioorganic & Medicinal Chemistry. PMID 28385597 DOI: 10.1016/J.Bmc.2017.03.047 |
0.75 |
|
| 2017 |
Hartley MD, Kirkemo LL, Banerji T, Scanlan TS. A thyroid hormone based strategy for correcting the biochemical abnormality in X-linked adrenoleukodystrophy (X-ALD). Endocrinology. PMID 28200172 DOI: 10.1210/En.2016-1842 |
0.357 |
|
| 2016 |
Fernando R, Placzek E, Reese EA, Placzek AT, Schwartz S, Trierweiler A, Niziol LM, Atkins S, Scanlan TS, Smith TJ. Elevated serum tetrac in Graves' disease: potential pathogenic role in thyroid-associated ophthalmopathy. The Journal of Clinical Endocrinology and Metabolism. jc20162762. PMID 27768856 DOI: 10.1210/Jc.2016-2762 |
0.395 |
|
| 2016 |
Devereaux J, Ferrara SJ, Banerji T, Placzek AT, Scanlan TS. Increasing Thyromimetic Potency through Halogen Substitution. Chemmedchem. PMID 27731931 DOI: 10.1002/Cmdc.201600408 |
0.802 |
|
| 2016 |
Placzek AT, Ferrara SJ, Hartley MD, Sanford-Crane HS, Meinig JM, Scanlan TS. Sobetirome prodrug esters with enhanced blood-brain barrier permeability. Bioorganic & Medicinal Chemistry. PMID 27707627 DOI: 10.1016/J.Bmc.2016.09.038 |
0.751 |
|
| 2016 |
Bronchain OJ, Chesneau A, Monsoro-Burq AH, Jolivet P, Paillard E, Scanlan TS, Demeneix BA, Sachs LM, Pollet N. Implication of thyroid hormone signaling in neural crest cells migration: Evidence from thyroid hormone receptor beta knockdown and NH3 antagonist studies. Molecular and Cellular Endocrinology. PMID 27619407 DOI: 10.1016/J.Mce.2016.09.007 |
0.394 |
|
| 2015 |
Placzek AT, Scanlan TS. New synthetic routes to thyroid hormone analogs: d6-sobetirome, (3)H-sobetirome, and the antagonist NH-3. Tetrahedron. 71: 5946-5951. PMID 28316349 DOI: 10.1016/J.Tet.2015.05.049 |
0.394 |
|
| 2014 |
Guo C, Chen X, Song H, Maynard MA, Zhou Y, Lobanov AV, Gladyshev VN, Ganis JJ, Wiley D, Jugo RH, Lee NY, Castroneves LA, Zon LI, Scanlan TS, Feldman HA, et al. Intrinsic expression of a multiexon type 3 deiodinase gene controls zebrafish embryo size. Endocrinology. 155: 4069-80. PMID 25004091 DOI: 10.1210/En.2013-2029 |
0.364 |
|
| 2013 |
Hackenmueller SA, Scanlan TS. THE SYNTHESIS OF (13)C9-(15)N-LABELED 3,5-DIIODOTHYRONINE AND THYROXINE. Synthetic Communications. 43: 1439-1446. PMID 28943663 DOI: 10.1080/00397911.2011.639005 |
0.406 |
|
| 2013 |
James TD, Moffett SX, Scanlan TS, Martin JV. Effects of acute microinjections of the thyroid hormone derivative 3-iodothyronamine to the preoptic region of adult male rats on sleep, thermoregulation and motor activity. Hormones and Behavior. 64: 81-8. PMID 23702093 DOI: 10.1016/J.Yhbeh.2013.05.004 |
0.31 |
|
| 2013 |
Haviland JA, Reiland H, Butz DE, Tonelli M, Porter WP, Zucchi R, Scanlan TS, Chiellini G, Assadi-Porter FM. NMR-based metabolomics and breath studies show lipid and protein catabolism during low dose chronic T(1)AM treatment. Obesity (Silver Spring, Md.). 21: 2538-44. PMID 23512955 DOI: 10.1002/Oby.20391 |
0.625 |
|
| 2012 |
Hackenmueller SA, Marchini M, Saba A, Zucchi R, Scanlan TS. Biosynthesis of 3-iodothyronamine (T1AM) is dependent on the sodium-iodide symporter and thyroperoxidase but does not involve extrathyroidal metabolism of T4 Endocrinology. 153: 5659-5667. PMID 22948220 DOI: 10.1210/En.2012-1254 |
0.333 |
|
| 2012 |
Goldberg IJ, Huang LS, Huggins LA, Yu S, Nagareddy PR, Scanlan TS, Ehrenkranz JR. Thyroid hormone reduces cholesterol via a non-LDL receptor-mediated pathway Endocrinology. 153: 5143-5149. PMID 22948212 DOI: 10.1210/En.2012-1572 |
0.42 |
|
| 2012 |
Hackenmueller SA, Scanlan TS. Identification and quantification of 3-iodothyronamine metabolites in mouse serum using liquid chromatography-tandem mass spectrometry Journal of Chromatography A. 1256: 89-97. PMID 22885046 DOI: 10.1016/J.Chroma.2012.07.052 |
0.321 |
|
| 2012 |
Roy G, Placzek E, Scanlan TS. ApoB-100-containing lipoproteins are major carriers of 3-iodothyronamine in circulation Journal of Biological Chemistry. 287: 1790-1800. PMID 22128163 DOI: 10.1074/Jbc.M111.275552 |
0.797 |
|
| 2012 |
Hoefig CS, Renko K, Piehl S, Scanlan TS, Bertoldi M, Opladen T, Hoffmann GF, Klein J, Blankenstein O, Schweizer U, Köhrle J. Does the aromatic l-amino acid decarboxylase contribute to thyronamine biosynthesis? Molecular and Cellular Endocrinology. 349: 195-201. PMID 22061622 DOI: 10.1016/J.Mce.2011.10.024 |
0.343 |
|
| 2012 |
Galli E, Marchini M, Saba A, Berti S, Tonacchera M, Vitti P, Scanlan TS, Iervasi G, Zucchi R. Detection of 3-iodothyronamine in human patients: A preliminary study Journal of Clinical Endocrinology and Metabolism. 97: E69-E74. PMID 22031514 DOI: 10.1210/Jc.2011-1115 |
0.33 |
|
| 2012 |
Scanlan TS, Fletterick RJ. In MemoriamJohn D. Baxter, M.D., 1940–2011 Thyroid. 22: 228-230. DOI: 10.1089/Thy.2012.2202.Obit |
0.367 |
|
| 2011 |
Frascarelli S, Ghelardoni S, Chiellini G, Galli E, Ronca F, Scanlan TS, Zucchi R. Cardioprotective effect of 3-iodothyronamine in perfused rat heart subjected to ischemia and reperfusion Cardiovascular Drugs and Therapy. 25: 307-313. PMID 21786214 DOI: 10.1007/S10557-011-6320-X |
0.641 |
|
| 2011 |
Venditti P, Napolitano G, Di Stefano L, Chiellini G, Zucchi R, Scanlan TS, Di Meo S. Effects of the thyroid hormone derivatives 3-iodothyronamine and thyronamine on rat liver oxidative capacity Molecular and Cellular Endocrinology. 341: 55-62. PMID 21664427 DOI: 10.1016/J.Mce.2011.05.013 |
0.624 |
|
| 2011 |
Scanlan TS. Endogenous 3-iodothyronamine (T1AM): More than we bargained for Journal of Clinical Endocrinology and Metabolism. 96: 1674-1676. PMID 21602461 DOI: 10.1210/Jc.2011-0688 |
0.391 |
|
| 2011 |
Agretti P, de Marco G, Russo L, Saba A, Raffaelli A, Marchini M, Chiellini G, Grasso L, Pinchera A, Vitti P, Scanlan TS, Zucchi R, Tonacchera M. 3-iodothyronamine metabolism and functional effects in FRTL5 thyroid cells Journal of Molecular Endocrinology. 47: 23-32. PMID 21511808 DOI: 10.1530/Jme-10-0168 |
0.626 |
|
| 2011 |
Grijota-Martínez C, Samarut E, Scanlan TS, Morte B, Bernal J. In vivo activity of the thyroid hormone receptor β- and α-selective agonists GC-24 and CO23 on rat liver, heart, and brain Endocrinology. 152: 1136-1142. PMID 21239431 DOI: 10.1210/En.2010-0813 |
0.466 |
|
| 2011 |
Figueira ACM, Saidemberg DM, Souza PCT, Martínez L, Scanlan TS, Baxter JD, Skaf MS, Palma MS, Webb P, Polikarpov I. Analysis of agonist and antagonist effects on thyroid hormone receptor conformation by hydrogen/deuterium exchange Molecular Endocrinology. 25: 15-31. PMID 21106879 DOI: 10.1210/Me.2010-0202 |
0.407 |
|
| 2011 |
Piehl S, Hoefig CS, Scanlan TS, Köhrle J. Thyronamines - Past, present, and future Endocrine Reviews. 32: 64-80. PMID 20880963 DOI: 10.1210/Er.2009-0040 |
0.435 |
|
| 2010 |
Saba A, Chiellini G, Frascarelli S, Marchini M, Ghelardoni S, Raffaelli A, Tonacchera M, Vitti P, Scanlan TS, Zucchi R. Tissue distribution and cardiac metabolism of 3-iodothyronamine Endocrinology. 151: 5063-5073. PMID 20739399 DOI: 10.1210/En.2010-0491 |
0.644 |
|
| 2010 |
Martinez De Mena R, Scanlan TS, Obregon MJ. The T3 receptor β1 isoform regulates UCP1 and D2 deiodinase in rat brown adipocytes Endocrinology. 151: 5074-5083. PMID 20719854 DOI: 10.1210/En.2010-0533 |
0.348 |
|
| 2010 |
Roepke TA, Bosch MA, Rick EA, Lee B, Wagner EJ, Seidlova-Wuttke D, Wuttke W, Scanlan TS, Rønnekleiv OK, Kelly MJ. Contribution of a membrane estrogen receptor to the estrogenic regulation of body temperature and energy homeostasis. Endocrinology. 151: 4926-37. PMID 20685867 DOI: 10.1210/En.2010-0573 |
0.345 |
|
| 2010 |
Ianculescu AG, Scanlan TS. 3-Iodothyronamine (T 1AM): A new chapter of thyroid hormone endocrinology? Molecular Biosystems. 6: 1338-1344. PMID 20623079 DOI: 10.1039/B926583J |
0.82 |
|
| 2010 |
Gompf HS, Greenberg JH, Aston-Jones G, Ianculescu AG, Scanlan TS, Dratman MB. 3-Monoiodothyronamine: the rationale for its action as an endogenous adrenergic-blocking neuromodulator. Brain Research. 1351: 130-40. PMID 20615397 DOI: 10.1016/J.Brainres.2010.06.067 |
0.796 |
|
| 2010 |
Schreiber T, Gassmann K, Götz C, Hübenthal U, Moors M, Krause G, Merk HF, Nguyen NH, Scanlan TS, Abel J, Rose CR, Fritsche E. Polybrominated diphenyl ethers induce developmental neurotoxicity in a human in vitro model: Evidence for endocrine disruption Environmental Health Perspectives. 118: 572-578. PMID 20368126 DOI: 10.1289/Ehp.0901435 |
0.575 |
|
| 2010 |
Venditti P, Chiellini G, Di Stefano L, Napolitano G, Zucchi R, Columbano A, Scanlan TS, Di Meo S. The TRβ-selective agonist, GC-1, stimulates mitochondrial oxidative processes to a lesser extent than triiodothyronine Journal of Endocrinology. 205: 279-289. PMID 20360308 DOI: 10.1677/Joe-10-0036 |
0.623 |
|
| 2010 |
Ianculescu AG, Friesema ECH, Visser TJ, Giacomini KM, Scanlan TS. Transport of thyroid hormones is selectively inhibited by 3-iodothyronamine Molecular Biosystems. 6: 1403-1410. PMID 20358049 DOI: 10.1039/B926588K |
0.807 |
|
| 2010 |
Panas HN, Lynch LJ, Vallender EJ, Xie Z, Chen GL, Lynn SK, Scanlan TS, Miller GM. Normal thermoregulatory responses to 3-iodothyronamine, trace amines and amphetamine-like psychostimulants in trace amine associated receptor 1 knockout mice. Journal of Neuroscience Research. 88: 1962-9. PMID 20155805 DOI: 10.1002/Jnr.22367 |
0.351 |
|
| 2010 |
Roohk DJ, Varady KA, Turner SM, Emson CL, Gelling RW, Shankaran M, Lindwall G, Shipp LE, Scanlan TS, Wang JC, Hellerstein MK. Differential in vivo effects on target pathways of a novel arylpyrazole glucocorticoid receptor modulator compared with prednisolone. The Journal of Pharmacology and Experimental Therapeutics. 333: 281-9. PMID 20065017 DOI: 10.1124/Jpet.109.162487 |
0.373 |
|
| 2010 |
Scanlan TS. Sobetirome: A case history of bench-to-clinic drug discovery and development Heart Failure Reviews. 15: 177-182. PMID 19002578 DOI: 10.1007/S10741-008-9122-X |
0.458 |
|
| 2010 |
SCANLAN T, SCHULTZ PG. ChemInform Abstract: Recent Advances in Catalytic Antibodies Cheminform. 24: no-no. DOI: 10.1002/chin.199326260 |
0.465 |
|
| 2010 |
SCANLAN TS, PRUDENT JR, SCHULTZ PG. ChemInform Abstract: Antibody-Catalyzed Hydrolysis of Phosphate Monoesters. Cheminform. 23: no-no. DOI: 10.1002/chin.199212102 |
0.464 |
|
| 2010 |
SHOKAT KM, KO MK, SCANLAN TS, KOCHERSPERGER L, YONKOVICH S, THAISRIVONGS S, SCHULTZ PG. ChemInform Abstract: Catalytic Antibodies: A New Class of Transition-State Analogues Used to Elicit Hydrolytic Antibodies Cheminform. 22: no-no. DOI: 10.1002/chin.199108378 |
0.576 |
|
| 2009 |
Cunha Lima ST, Nguyen NH, Togashi M, Apriletti JW, Nguyen P, Polikarpov I, Scanlan TS, Baxter JD, Webb P. Differential effects of TR ligands on hormone dissociation rates: Evidence for multiple ligand entry/exit pathways Journal of Steroid Biochemistry and Molecular Biology. 117: 125-131. PMID 19729063 DOI: 10.1016/J.Jsbmb.2009.08.003 |
0.642 |
|
| 2009 |
Lin BC, Suzawa M, Blind RD, Tobias SC, Bulun SE, Scanlan TS, Ingraham HA. Stimulating the GPR30 estrogen receptor with a novel tamoxifen analogue activates SF-1 and promotes endometrial cell proliferation Cancer Research. 69: 5415-5423. PMID 19549922 DOI: 10.1158/0008-5472.Can-08-1622 |
0.812 |
|
| 2009 |
Ghelardoni S, Suffredini S, Frascarelli S, Brogioni S, Chiellini G, Ronca-Testoni S, Grandy DK, Scanlan TS, Cerbai E, Zucchi R. Modulation of cardiac ionic homeostasis by 3-iodothyronamine Journal of Cellular and Molecular Medicine. 13: 3082-3090. PMID 19298522 DOI: 10.1111/J.1582-4934.2009.00728.X |
0.62 |
|
| 2009 |
Venditti P, Chiellini G, Bari A, Di Stefano L, Zucchi R, Columbano A, Scanlan TS, Di Meo S. T3 and the thyroid hormone beta-receptor agonist GC-1 differentially affect metabolic capacity and oxidative damage in rat tissues. The Journal of Experimental Biology. 212: 986-93. PMID 19282495 DOI: 10.1242/Jeb.021808 |
0.601 |
|
| 2009 |
Beber EH, Capelo LP, Fonseca TL, Costa CC, Lotfi CF, Scanlan TS, Gouveia CHA. The thyroid hormone receptor (TR) β-selective agonist GC-1 inhibits proliferation but induces differentiation and TR β mRNA expression in mouse and rat osteoblast-like cells Calcified Tissue International. 84: 324-333. PMID 19280098 DOI: 10.1007/S00223-009-9230-1 |
0.4 |
|
| 2009 |
Tan ES, Naylor JC, Groban ES, Bunzow JR, Jacobson MP, Grandy DK, Scanlan TS. The molecular basis of species-specific ligand activation of trace amine-associated receptor 1 (TAAR(1)). Acs Chemical Biology. 4: 209-20. PMID 19256523 DOI: 10.1021/Cb800304D |
0.648 |
|
| 2009 |
Scanlan TS. Minireview: 3-iodothyronamine (T 1AM): A new player on the thyroid endocrine team? Endocrinology. 150: 1108-1111. PMID 19116337 DOI: 10.1210/En.2008-1596 |
0.374 |
|
| 2009 |
Wood WJL, Geraci T, Nilsen A, DeBarber AE, Scanlan TS. Iodothyronamines are oxidatively deaminated to iodothyroacetic acids in vivo Chembiochem. 10: 361-365. PMID 19105176 DOI: 10.1002/Cbic.200800607 |
0.335 |
|
| 2009 |
Lanculescu AG, Giacomini KM, Scanlan TS. Identification and characterization of 3-iodothyronamine intracellular transport Endocrinology. 150: 1991-1999. PMID 19074582 DOI: 10.1210/En.2008-1339 |
0.344 |
|
| 2009 |
Denver RJ, Hu F, Scanlan TS, Furlow JD. Thyroid hormone receptor subtype specificity for hormone-dependent neurogenesis in Xenopus laevis Developmental Biology. 326: 155-168. PMID 19056375 DOI: 10.1016/J.Ydbio.2008.11.005 |
0.417 |
|
| 2008 |
Shah V, Nguyen P, Nguyen NH, Togashi M, Scanlan TS, Baxter JD, Webb P. Complex actions of thyroid hormone receptor antagonist NH-3 on gene promoters in different cell lines Molecular and Cellular Endocrinology. 296: 69-77. PMID 18930112 DOI: 10.1016/J.Mce.2008.09.016 |
0.674 |
|
| 2008 |
Snead AN, Miyakawa M, Tan ES, Scanlan TS. Trace amine-associated receptor 1 (TAAR1) is activated by amiodarone metabolites Bioorganic and Medicinal Chemistry Letters. 18: 5920-5922. PMID 18752950 DOI: 10.1016/J.Bmcl.2008.08.013 |
0.811 |
|
| 2008 |
Jeyakumar M, Webb P, Baxter JD, Scanlan TS, Katzenellenbogen JA. Quantification of ligand-regulated nuclear receptor corepressor and coactivator binding, key interactions determining ligand potency and efficacy for the thyroid hormone receptor. Biochemistry. 47: 7465-76. PMID 18558711 DOI: 10.1021/Bi800393U |
0.454 |
|
| 2008 |
Paris M, Escriva H, Schubert M, Brunet F, Brtko J, Ciesielski F, Roecklin D, Vivat-Hannah V, Jamin EL, Cravedi JP, Scanlan TS, Renaud JP, Holland ND, Laudet V. Amphioxus Postembryonic Development Reveals the Homology of Chordate Metamorphosis Current Biology. 18: 825-830. PMID 18514519 DOI: 10.1016/J.Cub.2008.04.078 |
0.429 |
|
| 2008 |
Frascarelli S, Ghelardoni S, Chiellini G, Vargiu R, Ronca-Testoni S, Scanlan TS, Grandy DK, Zucchi R. Cardiac effects of trace amines: Pharmacological characterization of trace amine-associated receptors European Journal of Pharmacology. 587: 231-236. PMID 18486124 DOI: 10.1016/J.Ejphar.2008.03.055 |
0.634 |
|
| 2008 |
Tan ES, Groban ES, Jacobson MP, Scanlan TS. Toward deciphering the code to aminergic G protein-coupled receptor drug design. Chemistry & Biology. 15: 343-53. PMID 18420141 DOI: 10.1016/J.Chembiol.2008.03.004 |
0.674 |
|
| 2008 |
Piehl S, Heberer T, Balizs G, Scanlan TS, Smits R, Koksch B, Köhrle J. Thyronamines are isozyme-specific substrates of deiodinases. Endocrinology. 149: 3037-45. PMID 18339710 DOI: 10.1210/En.2007-1678 |
0.386 |
|
| 2008 |
Ocasio CA, Scanlan TS. Characterization of thyroid hormone receptor α (TRα)-specific analogs with varying inner- and outer-ring substituents Bioorganic and Medicinal Chemistry. 16: 762-770. PMID 17988877 DOI: 10.1016/J.Bmc.2007.10.040 |
0.774 |
|
| 2008 |
Braulke LJ, Klingenspor M, DeBarber A, Tobias SC, Grandy DK, Scanlan TS, Heldmaier G. 3-Iodothyronamine: A novel hormone controlling the balance between glucose and lipid utilisation Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology. 178: 167-177. PMID 17912534 DOI: 10.1007/S00360-007-0208-X |
0.331 |
|
| 2008 |
Chiellini G, Ghelardoni S, Frascarelli S, Testoni S, Scanlan TS, Grandy DK, Zucchi R. 3-Iodothyronamine (T1AM) induces variation in phosphorylation pattern of tyrosine residues in rat heart Journal of Molecular and Cellular Cardiology. 44: 773-774. DOI: 10.1016/J.Yjmcc.2008.02.149 |
0.523 |
|
| 2008 |
Frascarelli S, Chiellini G, Ghelardoni S, Ronca-Testoni S, Grandy D, Scanlan T, Zucchi R. Cardioprotection by 3-iodothyronamine, a new endogenous chemical messenger Journal of Molecular and Cellular Cardiology. 44: 773. DOI: 10.1016/J.Yjmcc.2008.02.148 |
0.57 |
|
| 2007 |
Snead AN, Santos MS, Seal RP, Miyakawa M, Edwards RH, Scanlan TS. Thyronamines inhibit plasma membrane and vesicular monoamine transport. Acs Chemical Biology. 2: 390-8. PMID 17530732 DOI: 10.1021/Cb700057B |
0.818 |
|
| 2007 |
Tan ES, Miyakawa M, Bunzow JR, Grandy DK, Scanlan TS. Exploring the structure-activity relationship of the ethylamine portion of 3-iodothyronamine for rat and mouse trace amine-associated receptor 1 Journal of Medicinal Chemistry. 50: 2787-2798. PMID 17497842 DOI: 10.1021/Jm0700417 |
0.634 |
|
| 2007 |
Grover GJ, Dunn C, Nguyen NH, Boulet J, Dong G, Domogauer J, Barbounis P, Scanlan TS. Pharmacological profile of the thyroid hormone receptor antagonist NH3 in rats. The Journal of Pharmacology and Experimental Therapeutics. 322: 385-90. PMID 17440037 DOI: 10.1124/jpet.106.116152 |
0.582 |
|
| 2007 |
Villicev CM, Freitas FRS, Aoki MS, Taffarel C, Scanlan TS, Moriscot AS, Ribeiro MO, Bianco AC, Gouveia CHA. Thyroid hormone receptor β-specific agonist GC-1 increases energy expenditure and prevents fat-mass accumulation in rats Journal of Endocrinology. 193: 21-29. PMID 17400799 DOI: 10.1677/Joe.1.07066 |
0.383 |
|
| 2007 |
Chiellini G, Frascarelli S, Ghelardoni S, Carnicelli V, Tobias SC, DeBarber A, Brogioni S, Ronca-Testoni S, Cerbai E, Grandy DK, Scanlan TS, Zucchi R. Cardiac effects of 3-iodothyronamine: A new aminergic system modulating cardiac function Faseb Journal. 21: 1597-1608. PMID 17284482 DOI: 10.1096/Fj.06-7474Com |
0.592 |
|
| 2007 |
Pietsch CA, Scanlan TS, Anderson RJ. Thyronamines are substrates for human liver sulfotransferases. Endocrinology. 148: 1921-7. PMID 17204552 DOI: 10.1210/En.2006-1172 |
0.302 |
|
| 2007 |
Cvoro A, Paruthiyil S, Jones JO, Tzagarakis-Foster C, Clegg NJ, Tatomer D, Medina RT, Tagliaferri M, Schaufele F, Scanlan TS, Diamond MI, Cohen I, Leitman DC. Selective activation of estrogen receptor-beta transcriptional pathways by an herbal extract. Endocrinology. 148: 538-47. PMID 17095596 DOI: 10.1210/En.2006-0803 |
0.715 |
|
| 2007 |
Zucchi R, Chiellini G, Frascarelli S, Carnicelli V, Brogioni S, Ghelardoni S, Testoni S, Grandy DK, Cerbai E, Scanlan TS. Modulation of cardiac inotropic state by 3‐iodothyronamine: evidence for a novel signalling pathway mediated by trace amine‐associated receptors The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A246-D |
0.579 |
|
| 2007 |
Ocasio CA, Scanlan TS. ACS Chem. Biol. 2006, 1, 585–593Correction: Design and Characterization of a Thyroid Hormone Receptor α (TRα)-Specific Agonist Acs Chemical Biology. 2: 635-635. DOI: 10.1021/Cb700167W |
0.781 |
|
| 2006 |
Ocasio CA, Scanlan TS. Design and characterization of a thyroid hormone receptor alpha (TRalpha)-specific agonist. Acs Chemical Biology. 1: 585-593. PMID 17168554 DOI: 10.1021/Cb600311V |
0.806 |
|
| 2006 |
Flamant F, Baxter JD, Forrest D, Refetoff S, Samuels H, Scanlan TS, Vennström B, Samarut J. International union of pharmacology. LIX. The pharmacology and classification of the nuclear receptor superfamily: Thyroid hormone receptors Pharmacological Reviews. 58: 705-711. PMID 17132849 DOI: 10.1124/Pr.58.4.3 |
0.384 |
|
| 2006 |
Zucchi R, Chiellini G, Scanlan TS, Grandy DK. Trace amine-associated receptors and their ligands British Journal of Pharmacology. 149: 967-978. PMID 17088868 DOI: 10.1038/Sj.Bjp.0706948 |
0.642 |
|
| 2006 |
Havis E, Le Mevel S, Morvan Dubois G, Shi DL, Scanlan TS, Demeneix BA, Sachs LM. Unliganded thyroid hormone receptor is essential for Xenopus laevis eye development Embo Journal. 25: 4943-4951. PMID 17006540 DOI: 10.1038/Sj.Emboj.7601356 |
0.44 |
|
| 2006 |
Hiroi Y, Kim HH, Ying H, Furuya F, Huang Z, Simoncini T, Noma K, Ueki K, Nguyen NH, Scanlan TS, Moskowitz MA, Cheng SY, Liao JK. Rapid nongenomic actions of thyroid hormone. Proceedings of the National Academy of Sciences of the United States of America. 103: 14104-9. PMID 16966610 DOI: 10.1073/Pnas.0601600103 |
0.627 |
|
| 2006 |
Tobias SC, Qiu J, Kelly MJ, Scanlan TS. Synthesis and biological evaluation of SERMs with potent nongenomic estrogenic activity Chemmedchem. 1: 565-571. PMID 16892393 DOI: 10.1002/Cmdc.200500098 |
0.398 |
|
| 2006 |
Qiu J, Bosch MA, Tobias SC, Krust A, Graham SM, Murphy SJ, Korach KS, Chambon P, Scanlan TS, Rønnekleiv OK, Kelly MJ. A G-protein-coupled estrogen receptor is involved in hypothalamic control of energy homeostasis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5649-55. PMID 16723521 DOI: 10.1523/Jneurosci.0327-06.2006 |
0.385 |
|
| 2006 |
Columbano A, Pibiri M, Deidda M, Cossu C, Scanlan TS, Chiellini G, Muntoni S, Ledda-Columbano GM. The thyroid hormone receptor-β agonist GC-1 induces cell proliferation in rat liver and pancreas Endocrinology. 147: 3211-3218. PMID 16574785 DOI: 10.1210/En.2005-1561 |
0.691 |
|
| 2006 |
Wang JC, Shah N, Pantoja C, Meijsing SH, Ho JD, Scanlan TS, Yamamoto KR. Novel arylpyrazole compounds selectively modulate glucocorticoid receptor regulatory activity Genes and Development. 20: 689-699. PMID 16543221 DOI: 10.1101/Gad.1400506 |
0.478 |
|
| 2006 |
Hart ME, Suchland KL, Miyakawa M, Bunzow JR, Grandy DK, Scanlan TS. Trace amine-associated receptor agonists: Synthesis and evaluation of thyronamines and related analogues Journal of Medicinal Chemistry. 49: 1101-1112. PMID 16451074 DOI: 10.1021/Jm0505718 |
0.412 |
|
| 2006 |
Opitz R, Lutz I, Nguyen NH, Scanlan TS, Kloas W. Analysis of thyroid hormone receptor βa mRNA expression in Xenopus laevis tadpoles as a means to detect agonism and antagonism of thyroid hormone action Toxicology and Applied Pharmacology. 212: 1-13. PMID 16040072 DOI: 10.1016/J.Taap.2005.06.014 |
0.628 |
|
| 2006 |
Chiellini G, Ghelardoni S, Frascarelli S, Carnicelli V, Hart M, Ronca-Testoni S, Scanlan TS, Zucchi R. Stimulation of cardiac trace amine receptors by 3-iodothyronamine modulates tyrosine phosphorylation and induces cardioprotection Journal of Molecular and Cellular Cardiology. 40: 962. DOI: 10.1016/J.Yjmcc.2006.03.130 |
0.584 |
|
| 2006 |
Brogioni S, Chiellini G, Hart M, Scanlan TS, Cerbai E, Zucchi R. 3-Iodothyronamine affects calcium handling in isolated cardiomyocytes Journal of Molecular and Cellular Cardiology. 40: 925. DOI: 10.1016/j.yjmcc.2006.03.029 |
0.489 |
|
| 2005 |
Lin BC, Scanlan TS. Few things in life are "free": Cellular uptake of steroid hormones by an active transport mechanism Molecular Interventions. 5: 338-340. PMID 16394248 DOI: 10.1124/Mi.5.6.5 |
0.404 |
|
| 2005 |
Clegg NJ, Paruthiyil S, Leitman DC, Scanlan TS. Differential response of estrogen receptor subtypes to 1,3-diarylindene and 2,3-diarylindene ligands. Journal of Medicinal Chemistry. 48: 5989-6003. PMID 16162002 DOI: 10.1021/Jm050226I |
0.734 |
|
| 2005 |
Gloss B, Giannocco G, Swanson EA, Moriscot AS, Chiellini G, Scanlan T, Baxter JD, Dillmann WH. Different configurations of specific thyroid hormone response elements mediate opposite effects of thyroid hormone and GC-1 on gene expression Endocrinology. 146: 4926-4933. PMID 16081636 DOI: 10.1210/En.2005-0631 |
0.688 |
|
| 2005 |
Johansson L, Rudling M, Scanlan TS, Lundåsen T, Webb P, Baxter J, Angelin B, Parini P. Selective thyroid receptor modulation by GC-1 reduces serum lipids and stimulates steps of reverse cholesterol transport in euthyroid mice Proceedings of the National Academy of Sciences of the United States of America. 102: 10297-10302. PMID 16006512 DOI: 10.1073/Pnas.0504379102 |
0.394 |
|
| 2005 |
Fritsche E, Cline JE, Nguyen NH, Scanlan TS, Abel J. Polychlorinated biphenyls disturb differentiation of normal human neural progenitor cells: Clue for involvement of thyroid hormone receptors Environmental Health Perspectives. 113: 871-876. PMID 16002375 DOI: 10.1289/Ehp.7793 |
0.653 |
|
| 2005 |
Nguyen NH, Apriletti JW, Baxter JD, Scanlan TS. Hammett analysis of selective thyroid hormone receptor modulators reveals structural and electronic requirements for hormone antagonists Journal of the American Chemical Society. 127: 4599-4608. PMID 15796525 DOI: 10.1021/Ja0440093 |
0.638 |
|
| 2005 |
Freitas FRS, Capelo LP, O'Shea PJ, Jorgetti V, Moriscot AS, Scanlan TS, Williams GR, Zorn TMT, Gouveia CHA. The thyroid hormone receptor β-specific agonist GC-1 selectively affects the bone development of hypothyroid rats Journal of Bone and Mineral Research. 20: 294-304. PMID 15647824 DOI: 10.1359/Jbmr.041116 |
0.361 |
|
| 2005 |
Ocasio CA, Scanlan TS. Clinical prospects for new thyroid hormone analogues Current Opinion in Endocrinology and Diabetes. 12: 363-370. DOI: 10.1097/01.Med.0000177422.57988.B2 |
0.768 |
|
| 2004 |
Shah N, Scanlan TS. Design and evaluation of novel nonsteroidal dissociating glucocorticoid receptor ligands Bioorganic and Medicinal Chemistry Letters. 14: 5199-5203. PMID 15380227 DOI: 10.1016/J.Bmcl.2004.07.052 |
0.488 |
|
| 2004 |
Mishra MK, Wilson FE, Scanlan TS, Chiellini G. Thyroid hormone-dependent seasonality in American tree sparrows (Spizella arborea): Effects of GC-1, a thyroid receptor β-selective agonist, and of iopanoic acid, a deiodinase inhibitor Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology. 174: 471-479. PMID 15235810 DOI: 10.1007/s00360-004-0433-5 |
0.593 |
|
| 2004 |
Scanlan TS, Suchland KL, Hart ME, Chiellini G, Huang Y, Kruzich PJ, Frascarelli S, Crossley DA, Bunzow JR, Ronca-Testoni S, Lin ET, Hatton D, Zucchi R, Grandy DK. 3-Iodothyronamine is an endogenous and rapid-acting derivative of thyroid hormone Nature Medicine. 10: 638-642. PMID 15146179 DOI: 10.1038/Nm1051 |
0.685 |
|
| 2004 |
Baxter JD, Webb P, Grover G, Scanlan TS. Selective activation of thyroid hormone signaling pathways by GC-1: A new approach to controlling cholesterol and body weight Trends in Endocrinology and Metabolism. 15: 154-157. PMID 15109613 DOI: 10.1016/J.Tem.2004.03.008 |
0.335 |
|
| 2004 |
Moore JM, Galicia SJ, McReynolds AC, Nguyen NH, Scanlan TS, Guy RK. Quantitative proteomics of the thyroid hormone receptor-coregulator interactions. The Journal of Biological Chemistry. 279: 27584-90. PMID 15100213 DOI: 10.1074/Jbc.M403453200 |
0.695 |
|
| 2004 |
Furlow JD, Yang HY, Hsu M, Lim W, Ermio DJ, Chiellini G, Scanlan TS. Induction of Larval tissue resorption in Xenopus laevis tadpoles by the thyroid hormone receptor agonist GC-1 Journal of Biological Chemistry. 279: 26555-26562. PMID 15056670 DOI: 10.1074/Jbc.M402847200 |
0.722 |
|
| 2004 |
Dupré SM, Guissouma H, Flamant F, Seugnet I, Scanlan TS, Baxter JD, Samarut J, Demeneix BA, Becker N. Both thyroid hormone receptor (TR)β1 and TRβ2 isoforms contribute to the regulation of hypothalamic Thyrotropin-Releasing Hormone Endocrinology. 145: 2337-2345. PMID 14726446 DOI: 10.1210/En.2003-1209 |
0.414 |
|
| 2004 |
Grover GJ, Egan DM, Sleph PG, Beehler BC, Chiellini G, Nguyen NH, Baxter JD, Scanlan TS. Effects of the thyroid hormone receptor agonist GC-1 on metabolic rate and cholesterol in rats and primates: Selective actions relative to 3,5,3′-triiodo-L-thyronine Endocrinology. 145: 1656-1661. PMID 14701670 DOI: 10.1210/En.2003-0973 |
0.739 |
|
| 2004 |
Morte B, Manzano J, Scanlan TS, Vennström B, Bernal J. Aberrant Maturation of Astrocytes in Thyroid Hormone Receptor α1 Knockout Mice Reveals an Interplay between Thyroid Hormone Receptor Isoforms Endocrinology. 145: 1386-1391. PMID 14630717 DOI: 10.1210/En.2003-1123 |
0.418 |
|
| 2003 |
Yoshihara HAI, Scanlan TS. Selective thyroid hormone receptor modulators. Current Topics in Medicinal Chemistry. 3: 1601-1616. PMID 14683517 DOI: 10.2174/1568026033451682 |
0.356 |
|
| 2003 |
Borngraeber S, Budny MJ, Chiellini G, Cunha-Lima ST, Togashi M, Webb P, Baxter JD, Scanlan TS, Fletterick RJ. Ligand selectivity by seeking hydrophobicity in thyroid hormone receptor. Proceedings of the National Academy of Sciences of the United States of America. 100: 15358-63. PMID 14673100 DOI: 10.1073/Pnas.2136689100 |
0.78 |
|
| 2003 |
Yoshihara HAI, Nguyen NH, Scanlan TS. Design and Synthesis of Receptor Ligands Methods in Enzymology. 364: 71-91. PMID 14631840 DOI: 10.1016/S0076-6879(03)64005-X |
0.666 |
|
| 2003 |
Qiu J, Bosch MA, Tobias SC, Grandy DK, Scanlan TS, Rønnekleiv OK, Kelly MJ. Rapid Signaling of Estrogen in Hypothalamic Neurons Involves a Novel G-Protein-Coupled Estrogen Receptor that Activates Protein Kinase C Journal of Neuroscience. 23: 9529-9540. PMID 14573532 DOI: 10.1523/Jneurosci.23-29-09529.2003 |
0.377 |
|
| 2003 |
Manzano J, Morte B, Scanlan TS, Bernal J. Differential Effects of Triiodothyronine and the Thyroid Hormone Receptor β-Specific Agonist GC-1 on Thyroid Hormone Target Genes in the Brain Endocrinology. 144: 5480-5487. PMID 12959999 DOI: 10.1210/En.2003-0633 |
0.494 |
|
| 2003 |
Yoshihara HA, Apriletti JW, Baxter JD, Scanlan TS. Structural determinants of selective thyromimetics. Journal of Medicinal Chemistry. 46: 3152-61. PMID 12825953 DOI: 10.1021/Jm0301181 |
0.726 |
|
| 2003 |
Wade H, Scanlan TS. Binding and catalysis: a thermodynamic study on a catalytic antibody system. Chembiochem : a European Journal of Chemical Biology. 4: 537-40. PMID 12794866 DOI: 10.1002/Cbic.200300563 |
0.743 |
|
| 2002 |
Webb P, Nguyen NH, Chiellini G, Yoshihara HA, Cunha Lima ST, Apriletti JW, Ribeiro RC, Marimuthu A, West BL, Goede P, Mellstrom K, Nilsson S, Kushner PJ, Fletterick RJ, Scanlan TS, et al. Design of thyroid hormone receptor antagonists from first principles. The Journal of Steroid Biochemistry and Molecular Biology. 83: 59-73. PMID 12650702 DOI: 10.1016/S0960-0760(02)00270-4 |
0.805 |
|
| 2002 |
Nguyen NH, Apriletti JW, Cunha Lima ST, Webb P, Baxter JD, Scanlan TS. Rational design and synthesis of a novel thyroid hormone antagonist that blocks coactivator recruitment. Journal of Medicinal Chemistry. 45: 3310-20. PMID 12109914 DOI: 10.1021/Jm0201013 |
0.68 |
|
| 2002 |
Lim W, Nguyen NH, Yang HY, Scanlan TS, Furlow JD. A thyroid hormone antagonist that inhibits thyroid hormone action in vivo. The Journal of Biological Chemistry. 277: 35664-70. PMID 12095994 DOI: 10.1074/Jbc.M205608200 |
0.674 |
|
| 2002 |
Morte B, Manzano J, Scanlan T, Vennström B, Bernal J. Deletion of the thyroid hormone receptor alpha 1 prevents the structural alterations of the cerebellum induced by hypothyroidism. Proceedings of the National Academy of Sciences of the United States of America. 99: 3985-9. PMID 11891331 DOI: 10.1073/Pnas.062413299 |
0.435 |
|
| 2002 |
Weatherman RV, Chang CY, Clegg NJ, Carroll DC, Day RN, Baxter JD, McDonnell DP, Scanlan TS, Schaufele F. Ligand-selective interactions of ER detected in living cells by fluorescence resonance energy transfer. Molecular Endocrinology (Baltimore, Md.). 16: 487-96. PMID 11875107 DOI: 10.1210/Mend.16.3.0813 |
0.791 |
|
| 2002 |
Baxter JD, Goede P, Apriletti JW, West BL, Feng W, Mellstrom K, Fletterick RJ, Wagner RL, Kushner PJ, Ribeiro RC, Webb P, Scanlan TS, Nilsson S. Structure-based design and synthesis of a thyroid hormone receptor (TR) antagonist. Endocrinology. 143: 517-24. PMID 11796506 DOI: 10.1210/Endo.143.2.8617 |
0.657 |
|
| 2002 |
Chiellini G, Nguyen NH, Apriletti JW, Baxter JD, Scanlan TS. Synthesis and biological activity of novel thyroid hormone analogues: 5'-aryl substituted GC-1 derivatives. Bioorganic & Medicinal Chemistry. 10: 333-46. PMID 11741782 DOI: 10.1016/S0968-0896(01)00284-X |
0.751 |
|
| 2001 |
Scanlan TS, Yoshihara HA, Nguyen NH, Chiellini G. Selective thyromimetics: tissue-selective thyroid hormone analogs. Current Opinion in Drug Discovery & Development. 4: 614-22. PMID 12825456 |
0.83 |
|
| 2001 |
Weatherman RV, Carroll DC, Scanlan TS. Activity of a tamoxifen-raloxifene hybrid ligand for estrogen receptors at an AP-1 site. Bioorganic & Medicinal Chemistry Letters. 11: 3129-31. PMID 11720858 DOI: 10.1016/S0960-894X(01)00646-1 |
0.745 |
|
| 2001 |
Yoshihara HA, Apriletti JW, Baxter JD, Scanlan TS. A designed antagonist of the thyroid hormone receptor. Bioorganic & Medicinal Chemistry Letters. 11: 2821-5. PMID 11597408 DOI: 10.1016/S0960-894X(01)00521-2 |
0.768 |
|
| 2001 |
Ribeiro MO, Carvalho SD, Schultz JJ, Chiellini G, Scanlan TS, Bianco AC, Brent GA. Thyroid hormone--sympathetic interaction and adaptive thermogenesis are thyroid hormone receptor isoform--specific. The Journal of Clinical Investigation. 108: 97-105. PMID 11435461 DOI: 10.1172/JCI12584 |
0.656 |
|
| 2001 |
Baxter JD, Dillmann WH, West BL, Huber R, Furlow JD, Fletterick RJ, Webb P, Apriletti JW, Scanlan TS. Selective modulation of thyroid hormone receptor action. The Journal of Steroid Biochemistry and Molecular Biology. 76: 31-42. PMID 11384861 DOI: 10.1016/S0960-0760(01)00052-8 |
0.647 |
|
| 2001 |
Weatherman RV, Clegg NJ, Scanlan TS. Differential SERM activation of the estrogen receptors (ERalpha and ERbeta) at AP-1 sites. Chemistry & Biology. 8: 427-36. PMID 11358690 DOI: 10.1016/S1074-5521(01)00025-4 |
0.804 |
|
| 2001 |
Wagner RL, Huber BR, Shiau AK, Kelly A, Cunha Lima ST, Scanlan TS, Apriletti JW, Baxter JD, West BL, Fletterick RJ. Hormone selectivity in thyroid hormone receptors. Molecular Endocrinology (Baltimore, Md.). 15: 398-410. PMID 11222741 DOI: 10.1210/Mend.15.3.0608 |
0.623 |
|
| 2001 |
Person EC, Waite LL, Taylor RN, Scanlan TS. Albumin regulates induction of peroxisome proliferator-activated receptor-gamma (PPARgamma) by 15-deoxy-delta(12-14)-prostaglandin J(2) in vitro and may be an important regulator of PPARgamma function in vivo. Endocrinology. 142: 551-6. PMID 11159824 DOI: 10.1210/Endo.142.2.7965 |
0.387 |
|
| 2001 |
Weatherman RV, Scanlan TS. Unique protein determinants of the subtype-selective ligand responses of the estrogen receptors (ERalpha and ERbeta ) at AP-1 sites. The Journal of Biological Chemistry. 276: 3827-32. PMID 11060287 DOI: 10.1074/Jbc.M005414200 |
0.758 |
|
| 2000 |
Trost SU, Swanson E, Gloss B, Wang-Iverson DB, Zhang H, Volodarsky T, Grover GJ, Baxter JD, Chiellini G, Scanlan TS, Dillmann WH. The Thyroid Hormone Receptor-β-Selective Agonist GC-1 Differentially Affects Plasma Lipids and Cardiac Activity. Endocrinology. 141: 3057-3064. PMID 28204388 DOI: 10.1210/endo.141.9.7681 |
0.643 |
|
| 2000 |
Kushner PJ, Agard DA, Greene GL, Scanlan TS, Shiau AK, Uht RM, Webb P. Estrogen receptor pathways to AP-1. The Journal of Steroid Biochemistry and Molecular Biology. 74: 311-7. PMID 11162939 DOI: 10.1016/S0960-0760(00)00108-4 |
0.387 |
|
| 2000 |
Chiellini G, Nguyen NH, Yoshihara HA, Scanlan TS. Improved synthesis of the iodine-free thyromimetic GC-1. Bioorganic & Medicinal Chemistry Letters. 10: 2607-11. PMID 11128634 DOI: 10.1016/S0960-894X(00)00531-X |
0.767 |
|
| 2000 |
Waite LL, Person EC, Zhou Y, Lim KH, Scanlan TS, Taylor RN. Placental peroxisome proliferator-activated receptor-gamma is up-regulated by pregnancy serum. The Journal of Clinical Endocrinology and Metabolism. 85: 3808-14. PMID 11061543 DOI: 10.1210/Jcem.85.10.6847 |
0.311 |
|
| 2000 |
Bogan AA, Dallas-Yang Q, Ruse MD, Maeda Y, Jiang G, Nepomuceno L, Scanlan TS, Cohen FE, Sladek FM. Analysis of protein dimerization and ligand binding of orphan receptor HNF4alpha. Journal of Molecular Biology. 302: 831-51. PMID 10993727 DOI: 10.1006/Jmbi.2000.4099 |
0.362 |
|
| 2000 |
Webb P, Nguyen P, Valentine C, Weatherman RV, Scanlan TS, Kushner PJ. An antiestrogen-responsive estrogen receptor-alpha mutant (D351Y) shows weak AF-2 activity in the presence of tamoxifen. The Journal of Biological Chemistry. 275: 37552-8. PMID 10986290 DOI: 10.1074/Jbc.M007435200 |
0.743 |
|
| 2000 |
Trost SU, Swanson E, Gloss B, Wang-Iverson DB, Zhang H, Volodarsky T, Grover GJ, Baxter JD, Chiellini G, Scanlan TS, Dillmann WH. The thyroid hormone receptor-beta-selective agonist GC-1 differentially affects plasma lipids and cardiac activity. Endocrinology. 141: 3057-64. PMID 10965874 DOI: 10.1210/Endo.141.9.7681 |
0.681 |
|
| 1999 |
Weatherman RV, Fletterick RJ, Scanlan TS. Nuclear-receptor ligands and ligand-binding domains. Annual Review of Biochemistry. 68: 559-81. PMID 10872460 DOI: 10.1146/annurev.biochem.68.1.559 |
0.78 |
|
| 1998 |
Apriletti JW, Ribeiro RC, Wagner RL, Feng W, Webb P, Kushner PJ, West BL, Nilsson S, Scanlan TS, Fletterick RJ, Baxter JD. Molecular and structural biology of thyroid hormone receptors. Clinical and Experimental Pharmacology & Physiology. Supplement. 25: S2-11. PMID 9809185 DOI: 10.1111/J.1440-1681.1998.Tb02293.X |
0.629 |
|
| 1998 |
Yoshihara HA, Chiellini G, Mitchison TJ, Scanlan TS. An efficient substitution reaction for the preparation of thyroid hormone analogues. Bioorganic & Medicinal Chemistry. 6: 1179-83. PMID 9784860 DOI: 10.1016/S0968-0896(98)00085-6 |
0.795 |
|
| 1998 |
Buchbinder JL, Stephenson RC, Scanlan TS, Fletterick RJ. A comparison of the crystallographic structures of two catalytic antibodies with esterase activity. Journal of Molecular Biology. 282: 1033-41. PMID 9753552 DOI: 10.1006/Jmbi.1998.2025 |
0.515 |
|
| 1998 |
Ribeiro RC, Apriletti JW, Wagner RL, Feng W, Kushner PJ, Nilsson S, Scanlan TS, West BL, Fletterick RJ, Baxter JD. X-ray crystallographic and functional studies of thyroid hormone receptor. The Journal of Steroid Biochemistry and Molecular Biology. 65: 133-41. PMID 9699866 DOI: 10.1016/S0960-0760(98)00029-6 |
0.603 |
|
| 1998 |
Bogan AA, Cohen FE, Scanlan TS. Natural ligands of nuclear receptors have conserved volumes. Nature Structural Biology. 5: 679-81. PMID 9699629 DOI: 10.1038/1372 |
0.369 |
|
| 1998 |
Buchbinder JL, Stephenson RC, Dresser MJ, Pitera JW, Scanlan TS, Fletterick RJ. Biochemical Characterization and Crystallographic Structure of an Escherichia coli Protein from the Phosphotriesterase Gene Family. Biochemistry. 37: 10860. PMID 9692977 DOI: 10.1021/Bi985043V |
0.397 |
|
| 1998 |
Chiellini G, Apriletti JW, Yoshihara HA, Baxter JD, Ribeiro RC, Scanlan TS. A high-affinity subtype-selective agonist ligand for the thyroid hormone receptor. Chemistry & Biology. 5: 299-306. PMID 9653548 DOI: 10.1016/S1074-5521(98)90168-5 |
0.838 |
|
| 1998 |
Buchbinder JL, Stephenson RC, Dresser MJ, Pitera JW, Scanlan TS, Fletterick RJ. Biochemical characterization and crystallographic structure of an Escherichia coli protein from the phosphotriesterase gene family. Biochemistry. 37: 5096-106. PMID 9548740 DOI: 10.1021/Bi971707+ |
0.446 |
|
| 1998 |
Bishop AC, Moore D, Scanlan TS, Shokat KM. Corrigendum to “Screening a hydroxystilbene library for selective inhibition of the B cell antigen receptor kinase cascade” [Tetrahedron 53 (1997) 11995] Tetrahedron. 54: 1953. DOI: 10.1016/S0040-4020(97)10425-2 |
0.43 |
|
| 1997 |
Baca M, Scanlan TS, Stephenson RC, Wells JA. Phage display of a catalytic antibody to optimize affinity for transition-state analog binding. Proceedings of the National Academy of Sciences of the United States of America. 94: 10063-8. PMID 9294163 DOI: 10.1073/Pnas.94.19.10063 |
0.491 |
|
| 1997 |
Bishop AC, Moore D, Scanlan TS, Shokat KM. Screening a hydroxystilbene library for selective inhibition of the B cell antigen receptor kinase cascade Tetrahedron. 53: 11995-12004. DOI: 10.1016/S0040-4020(97)00712-6 |
0.482 |
|
| 1995 |
Williard R, Jammalamadaka V, Zava D, Benz CC, Hunt CA, Kushner PJ, Scanlan TS. Screening and characterization of estrogenic activity from a hydroxystilbene library. Chemistry & Biology. 2: 45-51. PMID 9383402 DOI: 10.1016/1074-5521(95)90079-9 |
0.401 |
|
| 1995 |
Guo J, Huang W, Zhou GW, Fletterick RJ, Scanlan TS. Mechanistically different catalytic antibodies obtained from immunization with a single transition-state analog. Proceedings of the National Academy of Sciences of the United States of America. 92: 1694-8. PMID 7878042 DOI: 10.1073/Pnas.92.5.1694 |
0.498 |
|
| 1994 |
Zhou GW, Guo J, Huang W, Fletterick RJ, Scanlan TS. Crystal structure of a catalytic antibody with a serine protease active site. Science (New York, N.Y.). 265: 1059-64. PMID 8066444 DOI: 10.1126/Science.8066444 |
0.454 |
|
| 1991 |
Scanlan TS, Prudent JR, Schultz PG. Antibody-catalyzed hydrolysis of phosphate monoesters Journal of the American Chemical Society. 113: 9397-9398. DOI: 10.1021/Ja00024A071 |
0.462 |
|
| 1990 |
Shokat KM, Ko MK, Scanlan TS, Kochersperger L, Yonkovich S, Thaisrivongs S, Schultz PG. Catalytic Antibodies: A New Class of Transition-State Analogues Used to Elicit Hydrolytic Antibodies Angewandte Chemie International Edition in English. 29: 1296-1303. DOI: 10.1002/Anie.199012961 |
0.601 |
|
| 1990 |
Shokat KM, Ko MK, Scanlan TS, Kochersperger L, Yonkovich S, Thaisrivongs S, Schultz PG. Katalytische Antikörper: Eine neue Klasse von Übergangszustands-Analoga zur Erzeugung hydrolytischer Antikörper Angewandte Chemie. 102: 1339-1346. DOI: 10.1002/Ange.19901021116 |
0.545 |
|
| Show low-probability matches. |
