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Xingshun Xu, Ph.D. - Publications

Affiliations: 
2007 East Tennessee State University, Johnson City, TN, United States 
Area:
Neuroscience Biology
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49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Chen X, Xin N, Pan Y, Zhu L, Yin P, Liu Q, Yang W, Xu X, Li S, Li XJ. Huntingtin-Associated Protein 1 in Mouse Hypothalamus Stabilizes Glucocorticoid Receptor in Stress Response. Frontiers in Cellular Neuroscience. 14: 125. PMID 32581713 DOI: 10.3389/Fncel.2020.00125  0.342
2018 Cheng Y, Sun M, Chen L, Li Y, Lin L, Yao B, Li Z, Wang Z, Chen J, Miao Z, Xin N, Huang L, Allen EG, Wu H, Xu X, et al. Ten-Eleven Translocation Proteins Modulate the Response to Environmental Stress in Mice. Cell Reports. 25: 3194-3203.e4. PMID 30540950 DOI: 10.1016/J.Celrep.2018.11.061  0.321
2018 Wang B, Zhang Y, Dong H, Gong S, Wei B, Luo M, Wang H, Wu X, Liu W, Xu X, Zheng Y, Sun M. Loss of Tctn3 causes neuronal apoptosis and neural tube defects in mice. Cell Death & Disease. 9: 520. PMID 29725084 DOI: 10.1038/S41419-018-0563-4  0.386
2018 Guo D, Zhang S, Sun H, Xu X, Hao Z, Mu C, Xu X, Wang G, Ren H. Tyrosine hydroxylase down-regulation after loss of Abelson helper integration site 1 (AHI1) promotes depression via the circadian clock pathway in mice. The Journal of Biological Chemistry. PMID 29449373 DOI: 10.1074/Jbc.Ra117.000618  0.346
2017 Wang Y, Wang B, Lu J, Shi H, Gong S, Wang Y, Hamdy RC, Chua BHL, Yang L, Xu X. Fisetin provides antidepressant effects by activating the TrkB signal pathway in mice. Journal of Neurochemistry. PMID 28945929 DOI: 10.1111/Jnc.14226  0.327
2017 Zhu J, Wu D, Zhao C, Luo M, Hamdy RC, Chua BHL, Xu X, Miao Z. Erratum to: Exogenous Adipokine Peptide Resistin Protects Against Focal Cerebral Ischemia/Reperfusion Injury in Mice. Neurochemical Research. PMID 28744754 DOI: 10.1007/S11064-017-2359-9  0.417
2017 Zhu J, Wu D, Zhao C, Luo M, Hamdy RC, Chua BHL, Xu X, Miao Z. Exogenous Adipokine Peptide Resistin Protects Against Focal Cerebral Ischemia/Reperfusion Injury in Mice. Neurochemical Research. PMID 28608237 DOI: 10.1007/s11064-017-2326-5  0.314
2016 Wang B, Zheng Y, Shi H, Du X, Zhang Y, Wei B, Luo M, Wang H, Wu X, Hua X, Sun M, Xu X. Zfp462 deficiency causes anxiety-like behaviors with excessive self-grooming in mice. Genes, Brain, and Behavior. PMID 27621227 DOI: 10.1111/Gbb.12339  0.317
2016 Xu Z, Guo X, Yang Y, Tucker D, Lu Y, Xin N, Zhang G, Yang L, Li J, Du X, Zhang Q, Xu X. Low-Level Laser Irradiation Improves Depression-Like Behaviors in Mice. Molecular Neurobiology. PMID 27379735 DOI: 10.1007/S12035-016-9983-2  0.326
2015 Zhang G, Chen L, Yang L, Hua X, Zhou B, Miao Z, Li J, Hu H, Namaka M, Kong J, Xu X. Combined use of spatial restraint stress and middle cerebral artery occlusion is a novel model of post-stroke depression in mice. Scientific Reports. 5: 16751. PMID 26572587 DOI: 10.1038/Srep16751  0.345
2015 Miao Z, He Y, Xin N, Sun M, Chen L, Lin L, Li J, Kong J, Jin P, Xu X. Altering 5-hydroxymethylcytosine modification impacts ischemic brain injury. Human Molecular Genetics. PMID 26231219 DOI: 10.1093/Hmg/Ddv307  0.374
2015 Li JJ, Li Q, Du HP, Wang YL, You SJ, Wang F, Xu XS, Cheng J, Cao YJ, Liu CF, Hu LF. Homocysteine Triggers Inflammatory Responses in Macrophages through Inhibiting CSE-H2S Signaling via DNA Hypermethylation of CSE Promoter. International Journal of Molecular Sciences. 16: 12560-77. PMID 26047341 DOI: 10.3390/Ijms160612560  0.319
2015 Li X, Zhao H, Tan X, Kostrzewa RM, Du G, Chen Y, Zhu J, Miao Z, Yu H, Kong J, Xu X. Inhibition of connexin43 improves functional recovery after ischemic brain injury in neonatal rats. Glia. 63: 1553-67. PMID 25988944 DOI: 10.1002/Glia.22826  0.384
2015 Ni J, Wang X, Chen S, Liu H, Wang Y, Xu X, Cheng J, Jia J, Zhen X. MicroRNA let-7c-5p protects against cerebral ischemia injury via mechanisms involving the inhibition of microglia activation. Brain, Behavior, and Immunity. PMID 25934573 DOI: 10.1016/J.Bbi.2015.04.014  0.331
2015 Jin X, Wang Y, Li X, Tan X, Miao Z, Chen Y, Hamdy RC, Chua BH, Kong J, Zhao H, Xu X. 7,8-Dihydroxy-4-methylcoumarin provides neuroprotection by increasing hippocalcin expression. Neurotoxicity Research. 27: 268-74. PMID 25752619 DOI: 10.1007/S12640-014-9507-7  0.401
2015 Yang B, Zhu J, Miao Z, Zhou B, Ge W, Zhao H, Xu X. Cystatin C is an Independent Risk Factor and Therapeutic Target for Acute Ischemic Stroke. Neurotoxicity Research. 28: 1-7. PMID 25697425 DOI: 10.1007/S12640-015-9522-3  0.336
2015 Tan X, Chen Y, Li J, Li X, Miao Z, Xin N, Zhu J, Ge W, Feng Y, Xu X. The inhibition of Cdk5 activity after hypoxia/ischemia injury reduces infarct size and promotes functional recovery in neonatal rats. Neuroscience. 290: 552-60. PMID 25665755 DOI: 10.1016/J.Neuroscience.2015.01.054  0.349
2015 Chen J, Sun M, Zhang X, Miao Z, Chua BHL, Hamdy RC, Zhang QG, Liu CF, Xu X. Increased oligodendrogenesis by humanin promotes axonal remyelination and neurological recovery in hypoxic/ischemic brains Hippocampus. 25: 62-71. PMID 25139533 DOI: 10.1002/Hipo.22350  0.356
2014 Xie Y, Liu ZH, Li XY, Zhou YD, Xu X, Hu LF, Zhang YL, Liu CF. Protection effect of [Gly14]-Humanin from apoptosis induced by high glucose in human umbilical vein endothelial cells. Diabetes Research and Clinical Practice. 106: 560-6. PMID 25451915 DOI: 10.1016/J.Diabres.2014.09.020  0.345
2014 Shi RY, Zhu SH, Li V, Gibson SB, Xu XS, Kong JM. BNIP3 interacting with LC3 triggers excessive mitophagy in delayed neuronal death in stroke. Cns Neuroscience & Therapeutics. 20: 1045-55. PMID 25230377 DOI: 10.1111/Cns.12325  0.349
2014 Chen J, Li J, Miao Z, Xu X, Liu CF. XAV939, a small molecular inhibitor, provides neuroprotective effects on oligodentrocytes. Journal of Neuroscience Research. 92: 1252-8. PMID 24861203 DOI: 10.1002/Jnr.23415  0.374
2014 Ren L, Qian X, Zhai L, Sun M, Miao Z, Li J, Xu X. Loss of Ahi1 impairs neurotransmitter release and causes depressive behaviors in mice. Plos One. 9: e93640. PMID 24691070 DOI: 10.1371/Journal.Pone.0093640  0.315
2014 Xiang J, Yang H, Zhao T, Sun M, Xu X, Zhou XF, Li SH, Li XJ. Huntingtin-associated protein 1 regulates postnatal neurogenesis and neurotrophin receptor sorting. The Journal of Clinical Investigation. 124: 85-98. PMID 24355921 DOI: 10.1172/Jci69206  0.371
2014 Du G, Tu H, Li X, Pei A, Chen J, Miao Z, Li J, Wang C, Xie H, Xu X, Zhao H. Daphnetin, a natural coumarin derivative, provides the neuroprotection against glutamate-induced toxicity in HT22 cells and ischemic brain injury. Neurochemical Research. 39: 269-75. PMID 24343531 DOI: 10.1007/S11064-013-1218-6  0.393
2013 Gu Q, Zhai L, Feng X, Chen J, Miao Z, Ren L, Qian X, Yu J, Li Y, Xu X, Liu CF. Apelin-36, a potent peptide, protects against ischemic brain injury by activating the PI3K/Akt pathway. Neurochemistry International. 63: 535-40. PMID 24083989 DOI: 10.1016/J.Neuint.2013.09.017  0.406
2013 Weng L, Lin YF, Li AL, Wang CE, Yan S, Sun M, Gaertig MA, Mitha N, Kosaka J, Wakabayashi T, Xu X, Tang B, Li S, Li XJ. Loss of Ahi1 affects early development by impairing BM88/Cend1-mediated neuronal differentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 8172-84. PMID 23658157 DOI: 10.1523/Jneurosci.0119-13.2013  0.342
2012 Wang C, Pei A, Chen J, Yu H, Sun ML, Liu CF, Xu X. A natural coumarin derivative esculetin offers neuroprotection on cerebral ischemia/reperfusion injury in mice. Journal of Neurochemistry. 121: 1007-13. PMID 22458555 DOI: 10.1111/J.1471-4159.2012.07744.X  0.412
2012 Yu H, Zhang ZL, Chen J, Pei A, Hua F, Qian X, He J, Liu CF, Xu X. Carvacrol, a food-additive, provides neuroprotection on focal cerebral ischemia/reperfusion injury in mice. Plos One. 7: e33584. PMID 22438954 DOI: 10.1371/Journal.Pone.0033584  0.403
2012 Zhu TG, Wang XX, Luo WF, Zhang QL, Huang TT, Xu XS, Liu CF. Protective effects of urate against 6-OHDA-induced cell injury in PC12 cells through antioxidant action. Neuroscience Letters. 506: 175-9. PMID 22094380 DOI: 10.1016/J.Neulet.2011.10.075  0.336
2012 Chen WW, Yu H, Fan HB, Zhang CC, Zhang M, Zhang C, Cheng Y, Kong J, Liu CF, Geng D, Xu X. RIP1 mediates the protection of geldanamycin on neuronal injury induced by oxygen-glucose deprivation combined with zVAD in primary cortical neurons. Journal of Neurochemistry. 120: 70-7. PMID 21985437 DOI: 10.1111/J.1471-4159.2011.07526.X  0.379
2011 Chen J, Chua KW, Chua CC, Yu H, Pei A, Chua BH, Hamdy RC, Xu X, Liu CF. Antioxidant activity of 7,8-dihydroxyflavone provides neuroprotection against glutamate-induced toxicity. Neuroscience Letters. 499: 181-5. PMID 21651962 DOI: 10.1016/J.Neulet.2011.05.054  0.324
2011 Xie Y, You SJ, Zhang YL, Han Q, Cao YJ, Xu XS, Yang YP, Li J, Liu CF. Protective role of autophagy in AGE-induced early injury of human vascular endothelial cells. Molecular Medicine Reports. 4: 459-64. PMID 21468592 DOI: 10.3892/Mmr.2011.460  0.335
2011 Zhang Z, Shi R, Weng J, Xu X, Li XM, Gao TM, Kong J. The proapoptotic member of the Bcl-2 family Bcl-2 / E1B-19K-interacting protein 3 is a mediator of caspase-independent neuronal death in excitotoxicity. The Febs Journal. 278: 134-42. PMID 21122071 DOI: 10.1111/J.1742-4658.2010.07939.X  0.332
2011 Wang J, Cheng Y, Yin J, Lu Q, Xu X, Yin X. protective effects of ginkgo biloba extract on 6-hydroxydopamine-induced apoptosis in pc12 cells Neural Regeneration Research. 6: 2565-2572. DOI: 10.3969/J.Issn.1673-5374.2011.33.001  0.311
2011 Ren L, Li Q, Zeng Z, Mou P, Liu X, Tang X, Lu Q, Xu X, Zhu L. A Humanin Analog Attenuates Platelet Responses to Vascular Injury Blood. 118: 1131-1131. DOI: 10.1182/Blood.V118.21.1131.1131  0.322
2010 Xu X, Yang H, Lin YF, Li X, Cape A, Ressler KJ, Li S, Li XJ. Neuronal Abelson helper integration site-1 (Ahi1) deficiency in mice alters TrkB signaling with a depressive phenotype. Proceedings of the National Academy of Sciences of the United States of America. 107: 19126-31. PMID 20956301 DOI: 10.1073/Pnas.1013032107  0.35
2010 Xu X, Chua KW, Chua CC, Liu CF, Hamdy RC, Chua BH. Synergistic protective effects of humanin and necrostatin-1 on hypoxia and ischemia/reperfusion injury. Brain Research. 1355: 189-94. PMID 20682300 DOI: 10.1016/J.Brainres.2010.07.080  0.394
2010 Xu X, Chua CC, Zhang M, Geng D, Liu CF, Hamdy RC, Chua BH. The role of PARP activation in glutamate-induced necroptosis in HT-22 cells. Brain Research. 1343: 206-12. PMID 20451505 DOI: 10.1016/J.Brainres.2010.04.080  0.377
2010 Li X, Wang CE, Huang S, Xu X, Li XJ, Li H, Li S. Inhibiting the ubiquitin-proteasome system leads to preferential accumulation of toxic N-terminal mutant huntingtin fragments. Human Molecular Genetics. 19: 2445-55. PMID 20354076 DOI: 10.1093/Hmg/Ddq127  0.337
2010 Lin YF, Xu X, Cape A, Li S, Li XJ. Huntingtin-associated protein-1 deficiency in orexin-producing neurons impairs neuronal process extension and leads to abnormal behavior in mice. The Journal of Biological Chemistry. 285: 15941-9. PMID 20304926 DOI: 10.1074/Jbc.M110.107318  0.334
2009 Chua CC, Gao J, Ho YS, Xu X, Kuo IC, Chua KY, Wang H, Hamdy RC, Reed JC, Chua BH. Over-expression of a modified bifunctional apoptosis regulator protects against cardiac injury and doxorubicin-induced cardiotoxicity in transgenic mice. Cardiovascular Research. 81: 20-7. PMID 18805781 DOI: 10.1093/Cvr/Cvn257  0.405
2008 Sheng G, Xu X, Lin YF, Wang CE, Rong J, Cheng D, Peng J, Jiang X, Li SH, Li XJ. Huntingtin-associated protein 1 interacts with Ahi1 to regulate cerebellar and brainstem development in mice. The Journal of Clinical Investigation. 118: 2785-95. PMID 18636121 DOI: 10.1172/Jci35339  0.349
2008 Gao J, Xiong Y, Ho YS, Liu X, Chua CC, Xu X, Wang H, Hamdy R, Chua BH. Glutathione peroxidase 1-deficient mice are more susceptible to doxorubicin-induced cardiotoxicity. Biochimica Et Biophysica Acta. 1783: 2020-9. PMID 18602426 DOI: 10.1016/J.Bbamcr.2008.05.027  0.637
2008 Xu X, Chua CC, Gao J, Chua KW, Wang H, Hamdy RC, Chua BH. Neuroprotective effect of humanin on cerebral ischemia/reperfusion injury is mediated by a PI3K/Akt pathway. Brain Research. 1227: 12-8. PMID 18590709 DOI: 10.1016/J.Brainres.2008.06.018  0.425
2008 Orr AL, Li S, Wang CE, Li H, Wang J, Rong J, Xu X, Mastroberardino PG, Greenamyre JT, Li XJ. N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 2783-92. PMID 18337408 DOI: 10.1523/Jneurosci.0106-08.2008  0.324
2007 Gao J, Chang Chua C, Chen Z, Wang H, Xu X, C Hamdy R, McMullen JR, Shioi T, Izumo S, Chua BH. Resistin, an adipocytokine, offers protection against acute myocardial infarction. Journal of Molecular and Cellular Cardiology. 43: 601-9. PMID 17904155 DOI: 10.1016/J.Yjmcc.2007.08.009  0.416
2007 Xu X, Chua CC, Kong J, Kostrzewa RM, Kumaraguru U, Hamdy RC, Chua BH. Necrostatin-1 protects against glutamate-induced glutathione depletion and caspase-independent cell death in HT-22 cells. Journal of Neurochemistry. 103: 2004-14. PMID 17760869 DOI: 10.1111/J.1471-4159.2007.04884.X  0.37
2007 Chua CC, Gao J, Ho YS, Xiong Y, Xu X, Chen Z, Hamdy RC, Chua BH. Overexpression of IAP-2 attenuates apoptosis and protects against myocardial ischemia/reperfusion injury in transgenic mice. Biochimica Et Biophysica Acta. 1773: 577-83. PMID 17321613 DOI: 10.1016/J.Bbamcr.2007.01.007  0.427
2006 Xu X, Chua CC, Gao J, Hamdy RC, Chua BH. Humanin is a novel neuroprotective agent against stroke. Stroke; a Journal of Cerebral Circulation. 37: 2613-9. PMID 16960089 DOI: 10.1161/01.Str.0000242772.94277.1F  0.378
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