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Ted Hansen - Publications

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 
Area:
Immunology, Biochemistry, Biomedical Engineering
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Year Citation  Score
2018 Wang X, Piersma SJ, Christopher NA, Dia YN, Christensen T, Lazear E, Yang L, Sluijter M, van Hall T, Hansen TH, Yokoyama WM, Fremont DH. A herpesvirus encoded Qa-1 mimic inhibits natural killer cell cytotoxicity through CD94/NKG2A receptor engagement. Elife. 7. PMID 30575523 DOI: 10.7554/Elife.38667  0.423
2017 Zhang X, Kim S, Hundal J, Herndon JM, Li S, Petti AA, Soysal SD, Li L, McLellan MD, Hoog J, Primeau T, Myers N, Vickery TL, Sturmoski M, Hagemann IS, ... ... Hansen T, et al. Breast cancer neoantigens can induce CD8 T cell responses and antitumor immunity. Cancer Immunology Research. PMID 28619968 DOI: 10.1158/2326-6066.Cir-16-0264  0.408
2016 Kaabinejadian S, McMurtrey CP, Kim S, Jain R, Bardet W, Schafer FB, Davenport JL, Martin AD, Diamond MS, Weidanz JA, Hansen TH, Hildebrand WH. Immunodominant West Nile Virus T Cell Epitopes Are Fewer in Number and Fashionably Late. Journal of Immunology (Baltimore, Md. : 1950). 196: 4263-73. PMID 27183642 DOI: 10.4049/Jimmunol.1501821  0.519
2016 Ussher JE, van Wilgenburg B, Hannaway RF, Ruustal K, Phalora P, Kurioka A, Hansen TH, Willberg CB, Phillips RE, Klenerman P. TLR signalling in human antigen-presenting cells regulates MR1-dependent activation of MAIT cells. European Journal of Immunology. PMID 27105778 DOI: 10.1002/eji.201545969  0.317
2015 Sakala IG, Kjer-Nielsen L, Eickhoff CS, Wang X, Blazevic A, Liu L, Fairlie DP, Rossjohn J, McCluskey J, Fremont DH, Hansen TH, Hoft DF. Functional Heterogeneity and Antimycobacterial Effects of Mouse Mucosal-Associated Invariant T Cells Specific for Riboflavin Metabolites. Journal of Immunology (Baltimore, Md. : 1950). 195: 587-601. PMID 26063000 DOI: 10.4049/Jimmunol.1402545  0.394
2015 Wilkinson-Ryan I, Kim J, Kim S, Ak F, Dodson L, Colonna M, Powell M, Mutch D, Spitzer D, Hansen T, Goedegebuure SP, Curiel D, Hawkins W. Incorporation of porcine adenovirus 4 fiber protein enhances infectivity of adenovirus vector on dendritic cells: implications for immune-mediated cancer therapy. Plos One. 10: e0125851. PMID 25933160 DOI: 10.1371/Journal.Pone.0125851  0.494
2015 Kurioka A, Ussher JE, Cosgrove C, Clough C, Fergusson JR, Smith K, Kang YH, Walker LJ, Hansen TH, Willberg CB, Klenerman P. MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets. Mucosal Immunology. 8: 429-40. PMID 25269706 DOI: 10.1038/Mi.2014.81  0.501
2014 Gold MC, McLaren JE, Reistetter JA, Smyk-Pearson S, Ladell K, Swarbrick GM, Yu YY, Hansen TH, Lund O, Nielsen M, Gerritsen B, Kesmir C, Miles JJ, Lewinsohn DA, Price DA, et al. MR1-restricted MAIT cells display ligand discrimination and pathogen selectivity through distinct T cell receptor usage. The Journal of Experimental Medicine. 211: 1601-10. PMID 25049333 DOI: 10.1084/jem.20140507  0.432
2014 Kim S, Pinto AK, Myers NB, Hawkins O, Doll K, Kaabinejadian S, Netland J, Bevan MJ, Weidanz JA, Hildebrand WH, Diamond MS, Hansen TH. A novel T-cell receptor mimic defines dendritic cells that present an immunodominant West Nile virus epitope in mice. European Journal of Immunology. 44: 1936-46. PMID 24723377 DOI: 10.1002/Eji.201444450  0.542
2014 Wilkinson-Ryan I, Kim J, Kim S, Powell M, Mutch D, Spitzer D, Hansen T, Goedebeuure S, Curiel D, Hawkins W. Incorporation of porcine adenovirus 4 fiber protein enhances infectivity of adenovirus vector on dendritic cells: Implications for immune-mediated cancer therapy Gynecologic Oncology. 133: 104-105. DOI: 10.1016/J.Ygyno.2014.03.278  0.314
2013 Reantragoon R, Corbett AJ, Sakala IG, Gherardin NA, Furness JB, Chen Z, Eckle SB, Uldrich AP, Birkinshaw RW, Patel O, Kostenko L, Meehan B, Kedzierska K, Liu L, Fairlie DP, ... Hansen TH, et al. Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells. The Journal of Experimental Medicine. 210: 2305-20. PMID 24101382 DOI: 10.1084/Jem.20130958  0.391
2013 King BC, Hamblin AD, Savage PM, Douglas LR, Hansen TH, French RR, Johnson PW, Glennie MJ. Antibody-peptide-MHC fusion conjugates target non-cognate T cells to kill tumour cells. Cancer Immunology, Immunotherapy : Cii. 62: 1093-105. PMID 23604105 DOI: 10.1007/s00262-013-1408-8  0.408
2013 Young MH, U'Ren L, Huang S, Mallevaey T, Scott-Browne J, Crawford F, Lantz O, Hansen TH, Kappler J, Marrack P, Gapin L. MAIT cell recognition of MR1 on bacterially infected and uninfected cells. Plos One. 8: e53789. PMID 23342002 DOI: 10.1371/Journal.Pone.0053789  0.405
2013 McCoy WH, Wang X, Yokoyama WM, Hansen TH, Fremont DH. Cowpox virus employs a two-pronged strategy to outflank MHCI antigen presentation. Molecular Immunology. 55: 156-8. PMID 23312338 DOI: 10.1016/J.Molimm.2012.11.011  0.41
2013 Mage MG, Dolan MA, Wang R, Boyd LF, Revilleza MJ, Robinson H, Natarajan K, Myers NB, Hansen TH, Margulies DH. A structural and molecular dynamics approach to understanding the peptide-receptive transition state of MHC-I molecules. Molecular Immunology. 55: 123-5. PMID 23200143 DOI: 10.1016/J.Molimm.2012.10.021  0.555
2012 McCoy WH, Wang X, Yokoyama WM, Hansen TH, Fremont DH. Structural mechanism of ER retrieval of MHC class I by cowpox. Plos Biology. 10: e1001432. PMID 23209377 DOI: 10.1371/Journal.Pbio.1001432  0.39
2012 Li L, Kim S, Herndon JM, Goedegebuure P, Belt BA, Satpathy AT, Fleming TP, Hansen TH, Murphy KM, Gillanders WE. Cross-dressed CD8α+/CD103+ dendritic cells prime CD8+ T cells following vaccination. Proceedings of the National Academy of Sciences of the United States of America. 109: 12716-21. PMID 22802630 DOI: 10.1073/pnas.1203468109  0.44
2012 Chua WJ, Truscott SM, Eickhoff CS, Blazevic A, Hoft DF, Hansen TH. Polyclonal mucosa-associated invariant T cells have unique innate functions in bacterial infection. Infection and Immunity. 80: 3256-67. PMID 22778103 DOI: 10.1128/Iai.00279-12  0.723
2012 Mage MG, Dolan MA, Wang R, Boyd LF, Revilleza MJ, Robinson H, Natarajan K, Myers NB, Hansen TH, Margulies DH. The peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics. Journal of Immunology (Baltimore, Md. : 1950). 189: 1391-9. PMID 22753930 DOI: 10.4049/Jimmunol.1200831  0.508
2012 Carreno BM, Becker-Hapak M, Chan M, Lie WR, Wang X, Hansen TH, Linette GP. Amino-terminal extended peptide single-chain trimers are potent synthetic agonists for memory human CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 188: 5839-49. PMID 22573808 DOI: 10.4049/jimmunol.1103647  0.558
2012 Reantragoon R, Kjer-Nielsen L, Patel O, Chen Z, Illing PT, Bhati M, Kostenko L, Bharadwaj M, Meehan B, Hansen TH, Godfrey DI, Rossjohn J, McCluskey J. Structural insight into MR1-mediated recognition of the mucosal associated invariant T cell receptor. The Journal of Experimental Medicine. 209: 761-74. PMID 22412157 DOI: 10.1084/Jem.20112095  0.4
2012 Herr RA, Wang X, Loh J, Virgin HW, Hansen TH. Newly discovered viral E3 ligase pK3 induces endoplasmic reticulum-associated degradation of class I major histocompatibility proteins and their membrane-bound chaperones. The Journal of Biological Chemistry. 287: 14467-79. PMID 22403403 DOI: 10.1074/Jbc.M111.325340  0.312
2012 Kim S, Zuiani A, Carrero JA, Hansen TH. Single chain MHC I trimer-based DNA vaccines for protection against Listeria monocytogenes infection. Vaccine. 30: 2178-86. PMID 22285270 DOI: 10.1016/j.vaccine.2012.01.012  0.525
2012 Loh J, Popkin DL, Droit L, Braaten DC, Zhao G, Zhang X, Vachharajani P, Myers N, Hansen TH, Virgin HW. Specific mutation of a gammaherpesvirus-expressed antigen in response to CD8 T cell selection in vivo. Journal of Virology. 86: 2887-93. PMID 22171269 DOI: 10.1128/Jvi.06101-11  0.394
2012 Mage M, Dolan M, Wang R, Boyd L, Revilleza M, Robinson H, Natarajan K, Myers N, Hansen T, Margulies D. The peptide-receptive transition state of MHC-I molecules: Insight from structure and molecular dynamics Molecular Immunology. 51: 24. DOI: 10.1016/J.Molimm.2012.02.064  0.578
2012 Hildebrand W, Weidanz J, Hansen T, Diamond M, McMurtrey C. Class I HLA presentation of west nile virus peptide epitopes Molecular Immunology. 51: 18. DOI: 10.1016/J.Molimm.2012.02.046  0.414
2012 Kim S, Li L, Carrero J, Diamond M, Gillanders W, Hansen T, Connolly J. DNA vaccination with plasmids encoding single chain of MHCI/peptide/β2 m complexes elicits robust CD8 T cell immunity and pathogen protection Molecular Immunology. 51: 12. DOI: 10.1016/J.Molimm.2012.02.027  0.549
2012 McMurtrey CP, Kim S, Jain R, Bardet W, Schafer F, Diamond MS, Weidanz J, Hansen T, Hildebrand W. 58-OR Human Immunology. 73: 46. DOI: 10.1016/J.Humimm.2012.07.090  0.547
2011 Hansen TH. Which lymphoid cells express MHC class II antigens; are TCRs encoded within the MHC? Journal of Immunology (Baltimore, Md. : 1950). 187: 2043-4. PMID 21856942 DOI: 10.4049/jimmunol.1101982  0.422
2011 Chua WJ, Kim S, Myers N, Huang S, Yu L, Fremont DH, Diamond MS, Hansen TH. Endogenous MHC-related protein 1 is transiently expressed on the plasma membrane in a conformation that activates mucosal-associated invariant T cells. Journal of Immunology (Baltimore, Md. : 1950). 186: 4744-50. PMID 21402896 DOI: 10.4049/Jimmunol.1003254  0.409
2010 Hansen TH, Connolly JM, Gould KG, Fremont DH. Basic and translational applications of engineered MHC class I proteins. Trends in Immunology. 31: 363-9. PMID 20832361 DOI: 10.1016/J.It.2010.07.003  0.529
2010 Chua WJ, Hansen TH. Bacteria, mucosal-associated invariant T cells and MR1. Immunology and Cell Biology. 88: 767-9. PMID 20733595 DOI: 10.1038/icb.2010.104  0.304
2010 Gold MC, Cerri S, Smyk-Pearson S, Cansler ME, Vogt TM, Delepine J, Winata E, Swarbrick GM, Chua WJ, Yu YY, Lantz O, Cook MS, Null MD, Jacoby DB, Harriff MJ, ... ... Hansen TH, et al. Human mucosal associated invariant T cells detect bacterially infected cells. Plos Biology. 8: e1000407. PMID 20613858 DOI: 10.1371/Journal.Pbio.1000407  0.414
2010 Kim S, Li L, McMurtrey CP, Hildebrand WH, Weidanz JA, Gillanders WE, Diamond MS, Hansen TH. Single-chain HLA-A2 MHC trimers that incorporate an immundominant peptide elicit protective T cell immunity against lethal West Nile virus infection. Journal of Immunology (Baltimore, Md. : 1950). 184: 4423-30. PMID 20212098 DOI: 10.4049/Jimmunol.0903955  0.574
2010 Li L, Herndon JM, Truscott SM, Hansen TH, Fleming TP, Goedegebuure P, Gillanders WE. Engineering superior DNA vaccines: MHC class I single chain trimers bypass antigen processing and enhance the immune response to low affinity antigens. Vaccine. 28: 1911-8. PMID 20188246 DOI: 10.1016/J.Vaccine.2009.10.096  0.764
2009 Hansen T, Yu YY, Fremont DH. Preparation of stable single-chain trimers engineered with peptide, beta2 microglobulin, and MHC heavy chain. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit17.5. PMID 19918946 DOI: 10.1002/0471142735.Im1705S87  0.642
2009 Byun M, Verweij MC, Pickup DJ, Wiertz EJ, Hansen TH, Yokoyama WM. Two mechanistically distinct immune evasion proteins of cowpox virus combine to avoid antiviral CD8 T cells. Cell Host & Microbe. 6: 422-32. PMID 19917497 DOI: 10.1016/J.Chom.2009.09.012  0.526
2009 Wang B, Primeau TM, Myers N, Rohrs HW, Gross ML, Lybarger L, Hansen TH, Connolly JM. A single peptide-MHC complex positively selects a diverse and specific CD8 T cell repertoire. Science (New York, N.Y.). 326: 871-4. PMID 19892989 DOI: 10.1126/Science.1177627  0.568
2009 Huang S, Martin E, Kim S, Yu L, Soudais C, Fremont DH, Lantz O, Hansen TH. MR1 antigen presentation to mucosal-associated invariant T cells was highly conserved in evolution. Proceedings of the National Academy of Sciences of the United States of America. 106: 8290-5. PMID 19416870 DOI: 10.1073/Pnas.0903196106  0.465
2008 Huang S, Gilfillan S, Kim S, Thompson B, Wang X, Sant AJ, Fremont DH, Lantz O, Hansen TH. MR1 uses an endocytic pathway to activate mucosal-associated invariant T cells. The Journal of Experimental Medicine. 205: 1201-11. PMID 18443227 DOI: 10.1084/Jem.20072579  0.499
2008 Truscott SM, Wang X, Lybarger L, Biddison WE, McBerry C, Martinko JM, Connolly JM, Linette GP, Fremont DH, Hansen TH, Carreno BM. Human major histocompatibility complex (MHC) class I molecules with disulfide traps secure disease-related antigenic peptides and exclude competitor peptides. The Journal of Biological Chemistry. 283: 7480-90. PMID 18195006 DOI: 10.1074/Jbc.M709935200  0.788
2007 Byun M, Wang X, Pak M, Hansen TH, Yokoyama WM. Cowpox virus exploits the endoplasmic reticulum retention pathway to inhibit MHC class I transport to the cell surface. Cell Host & Microbe. 2: 306-15. PMID 18005752 DOI: 10.1016/J.Chom.2007.09.002  0.431
2007 Mitaksov V, Truscott SM, Lybarger L, Connolly JM, Hansen TH, Fremont DH. Structural engineering of pMHC reagents for T cell vaccines and diagnostics. Chemistry & Biology. 14: 909-22. PMID 17719490 DOI: 10.1016/J.Chembiol.2007.07.010  0.782
2007 Purtha WE, Myers N, Mitaksov V, Sitati E, Connolly J, Fremont DH, Hansen TH, Diamond MS. Antigen-specific cytotoxic T lymphocytes protect against lethal West Nile virus encephalitis. European Journal of Immunology. 37: 1845-54. PMID 17559174 DOI: 10.1002/Eji.200737192  0.529
2007 Hansen TH, Huang S, Arnold PL, Fremont DH. Patterns of nonclassical MHC antigen presentation. Nature Immunology. 8: 563-8. PMID 17514210 DOI: 10.1038/Ni1475  0.486
2007 Truscott SM, Lybarger L, Martinko JM, Mitaksov VE, Kranz DM, Connolly JM, Fremont DH, Hansen TH. Disulfide bond engineering to trap peptides in the MHC class I binding groove. Journal of Immunology (Baltimore, Md. : 1950). 178: 6280-9. PMID 17475856 DOI: 10.4049/Jimmunol.178.10.6280  0.79
2006 Hansen TH, Lybarger L. Exciting applications of single chain trimers of MHC-I molecules. Cancer Immunology, Immunotherapy : Cii. 55: 235-6. PMID 16261380 DOI: 10.1007/S00262-005-0091-9  0.593
2005 Hansen TH, Lybarger L, Yu L, Mitaksov V, Fremont DH. Recognition of open conformers of classical MHC by chaperones and monoclonal antibodies. Immunological Reviews. 207: 100-11. PMID 16181330 DOI: 10.1111/J.0105-2896.2005.00315.X  0.452
2005 Primeau T, Myers NB, Yu YY, Lybarger L, Wang X, Truscott SM, Hansen TH, Connolly JM. Applications of major histocompatibility complex class I molecules expressed as single chains. Immunologic Research. 32: 109-21. PMID 16106063 DOI: 10.1385/Ir:32:1-3:109  0.782
2005 Kim S, Poursine-Laurent J, Truscott SM, Lybarger L, Song YJ, Yang L, French AR, Sunwoo JB, Lemieux S, Hansen TH, Yokoyama WM. Licensing of natural killer cells by host major histocompatibility complex class I molecules. Nature. 436: 709-13. PMID 16079848 DOI: 10.1038/Nature03847  0.716
2005 Huang S, Gilfillan S, Cella M, Miley MJ, Lantz O, Lybarger L, Fremont DH, Hansen TH. Evidence for MR1 antigen presentation to mucosal-associated invariant T cells. The Journal of Biological Chemistry. 280: 21183-93. PMID 15802267 DOI: 10.1074/Jbc.M501087200  0.491
2005 Huang CH, Peng S, He L, Tsai YC, Boyd DA, Hansen TH, Wu TC, Hung CF. Cancer immunotherapy using a DNA vaccine encoding a single-chain trimer of MHC class I linked to an HPV-16 E6 immunodominant CTL epitope. Gene Therapy. 12: 1180-6. PMID 15800656 DOI: 10.1038/Sj.Gt.3302519  0.413
2005 Treiner E, Duban L, Moura IC, Hansen T, Gilfillan S, Lantz O. Mucosal-associated invariant T (MAIT) cells: an evolutionarily conserved T cell subset. Microbes and Infection / Institut Pasteur. 7: 552-9. PMID 15777741 DOI: 10.1016/J.Micinf.2004.12.013  0.509
2005 Wang X, Connors R, Harris MR, Hansen TH, Lybarger L. Requirements for the selective degradation of endoplasmic reticulum-resident major histocompatibility complex class I proteins by the viral immune evasion molecule mK3. Journal of Virology. 79: 4099-108. PMID 15767411 DOI: 10.1128/Jvi.79.7.4099-4108.2005  0.397
2005 Lybarger L, Wang X, Harris M, Hansen TH. Viral immune evasion molecules attack the ER peptide-loading complex and exploit ER-associated degradation pathways. Current Opinion in Immunology. 17: 71-8. PMID 15653314 DOI: 10.1016/J.Coi.2004.11.009  0.524
2004 Wang X, Lybarger L, Connors R, Harris MR, Hansen TH. Model for the interaction of gammaherpesvirus 68 RING-CH finger protein mK3 with major histocompatibility complex class I and the peptide-loading complex. Journal of Virology. 78: 8673-86. PMID 15280476 DOI: 10.1128/Jvi.78.16.8673-8686.2004  0.38
2003 Hansen T, Myers N. Peptide induction of surface expression of class I MHC. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 18.11. PMID 18432904 DOI: 10.1002/0471142735.Im1811S57  0.585
2003 Miley MJ, Truscott SM, Yu YY, Gilfillan S, Fremont DH, Hansen TH, Lybarger L. Biochemical features of the MHC-related protein 1 consistent with an immunological function. Journal of Immunology (Baltimore, Md. : 1950). 170: 6090-8. PMID 12794138 DOI: 10.4049/Jimmunol.170.12.6090  0.737
2003 Lybarger L, Yu YY, Miley MJ, Fremont DH, Myers N, Primeau T, Truscott SM, Connolly JM, Hansen TH. Enhanced immune presentation of a single-chain major histocompatibility complex class I molecule engineered to optimize linkage of a C-terminally extended peptide. The Journal of Biological Chemistry. 278: 27105-11. PMID 12732632 DOI: 10.1074/Jbc.M303716200  0.788
2003 Hornell TM, Myers N, Hansen TH, Connolly JM. Homology between an alloantigen and a self MHC allele calibrates the avidity of the alloreactive T cell repertoire independent of TCR affinity. Journal of Immunology (Baltimore, Md. : 1950). 170: 4506-14. PMID 12707327  0.329
2003 Lybarger L, Wang X, Harris MR, Virgin HW, Hansen TH. Virus subversion of the MHC class I peptide-loading complex. Immunity. 18: 121-30. PMID 12530981 DOI: 10.1016/S1074-7613(02)00509-5  0.408
2002 Yu YY, Netuschil N, Lybarger L, Connolly JM, Hansen TH. Cutting edge: single-chain trimers of MHC class I molecules form stable structures that potently stimulate antigen-specific T cells and B cells. Journal of Immunology (Baltimore, Md. : 1950). 168: 3145-9. PMID 11907065 DOI: 10.4049/Jimmunol.168.7.3145  0.589
2002 Yu YY, Harris MR, Lybarger L, Kimpler LA, Myers NB, Virgin HW, Hansen TH. Physical association of the K3 protein of gamma-2 herpesvirus 68 with major histocompatibility complex class I molecules with impaired peptide and beta(2)-microglobulin assembly. Journal of Virology. 76: 2796-803. PMID 11861847 DOI: 10.1128/Jvi.76.6.2796-2803.2002  0.419
2001 Harris MR, Lybarger L, Myers NB, Hilbert C, Solheim JC, Hansen TH, Yu YY. Interactions of HLA-B27 with the peptide loading complex as revealed by heavy chain mutations. International Immunology. 13: 1275-82. PMID 11581172 DOI: 10.1093/Intimm/13.10.1275  0.519
2001 Lybarger L, Yu YY, Chun T, Wang CR, Grandea AG, Van Kaer L, Hansen TH. Tapasin enhances peptide-induced expression of H2-M3 molecules, but is not required for the retention of open conformers. Journal of Immunology (Baltimore, Md. : 1950). 167: 2097-105. PMID 11489993 DOI: 10.4049/Jimmunol.167.4.2097  0.428
2001 Harris MR, Lybarger L, Yu YYL, Myers NB, Hansen TH. Association of ERp57 with mouse MHC class I molecules is tapasin dependent and mimics that of calreticulin and not calnexin Journal of Immunology. 166: 6686-6692. PMID 11359824 DOI: 10.4049/Jimmunol.166.11.6686  0.444
2000 Myers NB, Harris MR, Connolly JM, Lybarger L, Yu YYL, Hansen TH. Kb, K(d), and L(d) molecules share common tapasin dependencies as determined using a novel epitope tag Journal of Immunology. 165: 5656-5663. PMID 11067922 DOI: 10.4049/Jimmunol.165.10.5656  0.497
2000 Hansen T, Balendiran G, Solheim J, Ostrov D, Nathenson S. Structural features of MHC class I molecules that might facilitate alternative pathways of presentation. Immunology Today. 21: 83-8. PMID 10652466 DOI: 10.1016/S0167-5699(98)01426-1  0.555
1999 Yu YY, Myers NB, Hilbert CM, Harris MR, Balendiran GK, Hansen TH. Definition and transfer of a serological epitope specific for peptide-empty forms of MHC class I. International Immunology. 11: 1897-906. PMID 10590255 DOI: 10.1093/intimm/11.12.1897  0.492
1999 Cook JR, Myers NB, Hansen TH. Peptide ligand structure influences the exchange of beta2-microglobulin by cell surface Kb. Molecular Immunology. 35: 929-34. PMID 9881688 DOI: 10.1016/S0161-5890(98)00080-7  0.453
1998 Hansen T. Ligand-free MHC class I conformation. Nature Structural Biology. 5: 340-1. PMID 9586990 DOI: 10.1038/nsb0598-340  0.484
1997 Lepley DM, Gillanders WE, Myers NB, Robinson RA, Beisel KW, Wisecarver JL, Pirruccello SJ, Lee DR, Hansen TH, Rubocki RJ. Biochemical and functional characterization of soluble multivalent MHC L(d)/Fc gamma 1 and L(d)/Fc mu chimeric proteins loaded with specific peptides. Transplantation. 63: 765-74. PMID 9075851 DOI: 10.1097/00007890-199703150-00025  0.426
1997 Gillanders WE, Hanson HL, Rubocki RJ, Hansen TH, Connolly JM. Class I-restricted cytotoxic T cell recognition of split peptide ligands. International Immunology. 9: 81-9. PMID 9043950 DOI: 10.1093/intimm/9.1.81  0.512
1996 Solheim JC, Cook JR, Hansen TH. Conformational changes induced in the MHC class I molecule by peptide and beta 2-microglobulin. Immunologic Research. 14: 200-17. PMID 8778210 DOI: 10.1007/BF02918217  0.518
1996 Myers NB, Wormstall E, Hansen TH. Differences among various class I molecules in competition for beta2m in vivo. Immunogenetics. 43: 384-7. PMID 8606059 DOI: 10.1007/BF02199807  0.307
1995 Smith JD, Solheim JC, Carreno BM, Hansen TH. Characterization of class I MHC folding intermediates and their disparate interactions with peptide and beta 2-microglobulin. Molecular Immunology. 32: 531-40. PMID 7783756 DOI: 10.1016/0161-5890(95)00013-5  0.433
1995 Solheim JC, Johnson NA, Carreno BM, Lie WR, Hansen TH. β2-microglobulin with an endoplasmic reticulum retention signal increases the surface expression of folded class I major histocompatibility complex molecules European Journal of Immunology. 25: 3011-3016. PMID 7489736 DOI: 10.1002/Eji.1830251104  0.444
1994 Alexander-miller M, Robinson RA, Smith JD, Gillanders WE, Harrison LG, Hansen TH, Connolly JM, Lee DR. Definition of TCR recognition sites on Ld-tum-complexes International Immunology. 6: 1699-1707. PMID 7865463 DOI: 10.1093/intimm/6.11.1699  0.48
1993 Saha BK, Shields JJ, Miller RD, Hansen TH, Shreffler DC. A highly polymorphic microsatellite in the class II Eb gene allows tracing of major histocompatibility complex evolution in mouse. Proceedings of the National Academy of Sciences of the United States of America. 90: 5312-6. PMID 8506379 DOI: 10.1073/pnas.90.11.5312  0.32
1993 Carreno BM, Winter CC, Taurog JD, Hansen TH, Biddison WE. Residues in pockets B and F of HLA-B27 are critical in the presentation of an influenza A virus nucleoprotein peptide and influence the stability of peptide - MHC complexes. International Immunology. 5: 353-60. PMID 8494822 DOI: 10.1093/intimm/5.4.353  0.382
1991 Schulz M, Aichele P, Schneider R, Hansen TH, Zinkernagel RM, Hengartner H. Major histocompatibility complex binding and T cell recognition of a viral nonapeptide containing a minimal tetrapeptide. European Journal of Immunology. 21: 1181-5. PMID 1709866 DOI: 10.1002/eji.1830210513  0.501
1991 Lie WR, Myers NB, Connolly JM, Gorka J, Lee DR, Hansen TH. The specific binding of peptide ligand to Ld class I major histocompatibility complex molecules determines their antigenic structure Journal of Experimental Medicine. 173: 449-459. PMID 1703208 DOI: 10.1084/jem.173.2.449  0.5
1989 Keeney JB, Hansen TH. Cis-acting elements determine the locus-specific shutoff of class I major histocompatibility genes in murine S49 lymphoma sublines. Proceedings of the National Academy of Sciences of the United States of America. 86: 6288-92. PMID 2762327 DOI: 10.1073/pnas.86.16.6288  0.329
1987 Lee DR, Lillehoj EP, Myers NB, Coligan JE, Hansen TH. Structural analyses define an additional H-2D region class I antigen that is expressed by a variant mouse strain. Molecular Immunology. 23: 1093-102. PMID 3796620 DOI: 10.1016/0161-5890(86)90007-6  0.337
1984 Lillehoj EP, Hansen TH, Sachs DH, Coligan JE. Primary structural evidence that the H-2Dq region encodes at least three distinct gene products: Dq, Lq, and Rq. Proceedings of the National Academy of Sciences of the United States of America. 81: 2499-503. PMID 6585810 DOI: 10.1073/pnas.81.8.2499  0.333
Low-probability matches (unlikely to be authored by this person)
2009 Markiewicz MA, Wise EL, Buchwald ZS, Cheney EE, Hansen TH, Suri A, Cemerski S, Allen PM, Shaw AS. IL-12 enhances CTL synapse formation and induces self-reactivity. Journal of Immunology (Baltimore, Md. : 1950). 182: 1351-61. PMID 19155481 DOI: 10.4049/Jimmunol.182.3.1351  0.299
1985 Tse HY, Kanamori S, Walsh WD, Hansen TH. The murine bm12 gene conversion provides evidence that T cells recognize predominantly Ia conformation Proceedings of the National Academy of Sciences of the United States of America. 82: 7058-7062. PMID 3931082  0.285
2009 Hansen TH, Bouvier M. MHC class I antigen presentation: learning from viral evasion strategies. Nature Reviews. Immunology. 9: 503-13. PMID 19498380 DOI: 10.1038/nri2575  0.276
1995 Linette GP, Grusby MJ, Hedrick SM, Hansen TH, Glimcher LH, Korsmeyer SJ. Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points. Immunity. 1: 197-205. PMID 7889408 DOI: 10.1016/1074-7613(94)90098-1  0.276
2013 Cosgrove C, Ussher JE, Rauch A, Gärtner K, Kurioka A, Hühn MH, Adelmann K, Kang YH, Fergusson JR, Simmonds P, Goulder P, Hansen TH, Fox J, Günthard HF, Khanna N, et al. Early and nonreversible decrease of CD161++ /MAIT cells in HIV infection. Blood. 121: 951-61. PMID 23255555 DOI: 10.1182/Blood-2012-06-436436  0.275
2013 Wang X, Yu YY, Myers N, Hansen TH. Decoupling the role of ubiquitination for the dislocation versus degradation of major histocompatibility complex (MHC) class I proteins during endoplasmic reticulum-associated degradation (ERAD). The Journal of Biological Chemistry. 288: 23295-306. PMID 23801327 DOI: 10.1074/jbc.M113.482018  0.273
1992 Johnson NA, Keeney JB, Hedayat M, Clary KW, Kranz DM, Hansen TH. T cell receptor rearrangements in various S49 lymphoma sublines. Molecular Immunology. 29: 1325-35. PMID 1328877 DOI: 10.1016/0161-5890(92)90169-X  0.263
2004 Jaramillo A, Narayanan K, Campbell LG, Benshoff ND, Lybarger L, Hansen TH, Fleming TP, Dietz JR, Mohanakumar T. Recognition of HLA-A2-restricted mammaglobin-A-derived epitopes by CD8+ cytotoxic T lymphocytes from breast cancer patients. Breast Cancer Research and Treatment. 88: 29-41. PMID 15538043 DOI: 10.1007/S10549-004-8918-1  0.259
1979 Biddison WE, Hansen TH, Levy RB, Doherty PC. Involvement of H-2L gene products in virus-immune T-cell recognition. Evidence for an H-2L-restricted T-cell response. The Journal of Experimental Medicine. 148: 1678-86. PMID 82606 DOI: 10.1084/Jem.148.6.1678  0.257
2008 Wang X, Herr RA, Hansen T. Viral and cellular MARCH ubiquitin ligases and cancer. Seminars in Cancer Biology. 18: 441-50. PMID 18948196 DOI: 10.1016/J.Semcancer.2008.09.002  0.254
1988 Lee DR, Rubocki RJ, Lie WR, Hansen TH. The murine MHC class I genes, H-2Dq and H-2Lq, are strikingly homologous to each other, H-2Ld, and two genes reported to encode tumor-specific antigens. The Journal of Experimental Medicine. 168: 1719-39. PMID 3263465 DOI: 10.1084/jem.168.5.1719  0.243
2007 Wang X, Herr RA, Chua WJ, Lybarger L, Wiertz EJ, Hansen TH. Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3. The Journal of Cell Biology. 177: 613-24. PMID 17502423 DOI: 10.1083/Jcb.200611063  0.239
1985 Melino MR, Epstein SL, Tse HY, Sachs DH, Hansen TH. Characterization of a dominant anti-Ia idiotype using the Ia mutant mouse strain B6.C-H-2bm12 Molecular Immunology. 22: 417-426. PMID 3861936 DOI: 10.1016/0161-5890(85)90126-9  0.235
2013 Cosgrove C, Ussher JE, Rauch A, Gärtner K, Kurioka A, Hühn MH, Adelmann K, Kang Y, Fergusson JR, Simmonds P, Goulder P, Hansen TH, Fox J, Günthard HF, Khanna N, et al. Early and non-reversible decrease of CD161++/mucosal associated invariant T cells in HIV infection Journal of Infection. 67: 342-343. DOI: 10.1016/J.Jinf.2013.07.003  0.235
2014 Ussher JE, Bilton M, Attwod E, Shadwell J, Richardson R, de Lara C, Mettke E, Kurioka A, Hansen TH, Klenerman P, Willberg CB. CD161++ CD8+ T cells, including the MAIT cell subset, are specifically activated by IL-12+IL-18 in a TCR-independent manner. European Journal of Immunology. 44: 195-203. PMID 24019201 DOI: 10.1002/eji.201343509  0.232
1987 Rubocki RJ, Hansen TH, Lee DR. Molecular studies of murine mutant BALB/c-H-2dm2 define a deletion of several class I genes including the entire H-2Ld gene. Proceedings of the National Academy of Sciences of the United States of America. 83: 9606-10. PMID 2879284 DOI: 10.1073/pnas.83.24.9606  0.231
1981 Lin CC, Rosenthal AS, Passmore HC, Hansen TH. Selective loss of antigen-specific Ir gene function in IA mutant B6.C-H-2bm12 is an antigen presenting cell defect. Proceedings of the National Academy of Sciences of the United States of America. 78: 6406-10. PMID 7031650 DOI: 10.1073/pnas.78.10.6406  0.228
2002 Smith RA, Myers NB, Robinson M, Hansen TH, Lee DR. Polymorphism at position 97 in MHC class I molecules affects peptide specificity, cell surface stability, and affinity for beta2-microglobulin. Journal of Immunology (Baltimore, Md. : 1950). 169: 3105-11. PMID 12218127  0.225
1981 Lin CS, Rosenthal AS, Hansen TH. I-A mutation resulted in a selective loss of an antigen-specific Ir gene function. Journal of Supramolecular Structure and Cellular Biochemistry. 16: 115-20. PMID 6170758 DOI: 10.1002/jsscb.1981.380160202  0.21
1977 Hansen TH, Cullen SE, Melvold R, Kohn H, Flaherty L, Sachs DH. Mutation in a new H-2-associated histocompatibility gene closely linked to H-2D. The Journal of Experimental Medicine. 145: 1550-8. PMID 68094 DOI: 10.1084/jem.145.6.1550  0.205
2006 Wang X, Ye Y, Lencer W, Hansen TH. The viral E3 ubiquitin ligase mK3 uses the Derlin/p97 endoplasmic reticulum-associated degradation pathway to mediate down-regulation of major histocompatibility complex class I proteins. The Journal of Biological Chemistry. 281: 8636-44. PMID 16446359 DOI: 10.1074/Jbc.M513920200  0.191
2012 McCoy WH, Wang X, Yokoyama WM, Hansen TH, Fremont D. Structural basis of MHCI antigen presentation sabotage by cowpox CPXV203 Molecular Immunology. 51: 14. DOI: 10.1016/J.Molimm.2012.02.034  0.19
1990 Rubocki RJ, Lee DR, Lie WR, Myers NB, Hansen TH. Molecular evidence that the H-2D and H-2L genes arose by duplication. Differences between the evolution of the class I genes in mice and humans. The Journal of Experimental Medicine. 171: 2043-61. PMID 2351932 DOI: 10.1084/jem.171.6.2043  0.189
2021 Li L, Zhang X, Wang X, Kim SW, Herndon JM, Becker-Hapak MK, Carreno BM, Myers NB, Sturmoski MA, McLellan MD, Miller CA, Johanns TM, Tan BR, Dunn GP, Fleming TP, ... Hansen TH, et al. Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation. Genome Medicine. 13: 56. PMID 33879241 DOI: 10.1186/s13073-021-00872-4  0.183
1974 Hansen TH, Krasteff TN, Shreffler DC. Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp. Biochemical Genetics. 12: 281-93. PMID 4216347 DOI: 10.1007/BF00485949  0.172
1997 Cook JR, Wormstall EM, Hornell T, Russell J, Connolly JM, Hansen TH. Quantitation of the cell surface level of L(D) resulting in positive versus negative selection of the 2C transgenic T cell receptor in vivo Immunity. 7: 233-241. PMID 9285408 DOI: 10.1016/S1074-7613(00)80526-9  0.172
2012 Wang X, Herr RA, Hansen TH. Ubiquitination of substrates by esterification. Traffic (Copenhagen, Denmark). 13: 19-24. PMID 21883762 DOI: 10.1111/j.1600-0854.2011.01269.x  0.168
1980 Hansen TH, Ivanyi P, Levy RB, Sachs DH. Cross-reactivity among the products of three nonallelic H-2 loci, H-2Ld, H-2Dq, and H-2Kk. Transplantation. 28: 339-42. PMID 505544 DOI: 10.1097/00007890-197910000-00015  0.168
1976 David CS, Hansen TH, Shreffler C. Studies on recombination within the mouse H-2 gene complex. III. Further serological analyses of the H-2t haplotypes. Tissue Antigens. 6: 353-65. PMID 1216250 DOI: 10.1111/J.1399-0039.1975.TB00655.X  0.167
2012 Gautiar EL, Shay T, Miller J, Greter M, Jakubzick C, Ivanov S, Helft J, Chow A, Elpek KG, Gordonov S, Mazloom AR, Ma'Ayan A, Chua WJ, Hansen TH, Turley SJ, et al. Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages Nature Immunology. 13: 1118-1128. PMID 23023392 DOI: 10.1038/Ni.2419  0.159
2009 Herr RA, Harris J, Fang S, Wang X, Hansen TH. Role of the RING-CH domain of viral ligase mK3 in ubiquitination of non-lysine and lysine MHC I residues. Traffic (Copenhagen, Denmark). 10: 1301-17. PMID 19531064 DOI: 10.1111/J.1600-0854.2009.00946.X  0.155
1980 Coligan JE, Kindt TJ, Nairn R, Nathenson SG, Sachs DH, Hansen TH. Primary structural studies of an H-2L molecule confirm that it is a unique gene product with homology to H-2K and H-2D antigens. Proceedings of the National Academy of Sciences of the United States of America. 77: 1134-8. PMID 6928664 DOI: 10.1073/Pnas.77.2.1134  0.154
1983 Hansen TH, Ozato K, Sachs DH. Heterogeneity of H-2D region associated genes and gene products. Advances in Immunology. 34: 39-70. PMID 6195894 DOI: 10.1016/S0065-2776(08)60376-4  0.152
1977 Hansen TH, Cullen SE, Sachs DH. Immunochemical evidence for an additional H-2 region closely linked to H-2D. The Journal of Experimental Medicine. 145: 438-42. PMID 64585 DOI: 10.1084/jem.145.2.438  0.151
1984 Hansen TH, Spinella DG, Lee DR, Shreffler DC. The immunogenetics of the mouse major histocompatibility gene complex. Annual Review of Genetics. 18: 99-129. PMID 6397127 DOI: 10.1146/annurev.ge.18.120184.000531  0.149
2011 Li L, Goedegebuure P, Mardis ER, Ellis MJ, Zhang X, Herndon JM, Fleming TP, Carreno BM, Hansen TH, Gillanders WE. Cancer genome sequencing and its implications for personalized cancer vaccines. Cancers. 3: 4191-211. PMID 24213133 DOI: 10.3390/cancers3044191  0.144
1978 Flaherty L, Zimmerman D, Hansen TH. Further serological analysis of the Qa antigens: Analysis of an anti-H-2.28 serum Immunogenetics. 6: 245-251. DOI: 10.1007/BF01563914  0.142
1975 Hansen TH, Shin HS, Shreffler DC. Evidence for the involvement of the Ss protein of the mouse in the hemolytic complement system. The Journal of Experimental Medicine. 141: 1216-20. PMID 805206 DOI: 10.1084/jem.141.5.1216  0.126
2012 Chua WJ, Hansen TH. Immunology: Vitamins prime immunity. Nature. 491: 680-1. PMID 23192143 DOI: 10.1038/491680a  0.119
1980 Hansen TH, Melvold RW, Arn JS, Sachs DH. Evidence for mutation in an I-A gene. Nature. 285: 340-1. PMID 7374785 DOI: 10.1038/285340a0  0.116
1996 Jiang PP, Frederick K, Hansen TH, Miller RD. Localization of the mouse gene releasing sex-limited expression of Slp. Proceedings of the National Academy of Sciences of the United States of America. 93: 913-7. PMID 8570659 DOI: 10.1073/pnas.93.2.913  0.1
2011 Li L, Goedegebuure P, Mardis ER, Ellis MJC, Zhang X, Herndon JM, Fleming TP, Carreno BM, Hansen TH, Gillanders WE. Cancer genome sequencing and its implications for personalized cancer vaccines Cancers. 3: 4191-4211. DOI: 10.3390/cancers3044191  0.088
2018 Xu Z, Zinchik S, Kolapkar SS, Bar-Ziv E, Hansen T, Conn D, McDonald AG. Properties of Torrefied U.S. Waste Blends Frontiers in Energy Research. 6. DOI: 10.3389/Fenrg.2018.00065  0.045
2009 Wang X, Herr RA, Rabelink M, Hoeben RC, Wiertz EJ, Hansen TH. Ube2j2 ubiquitinates hydroxylated amino acids on ER-associated degradation substrates. The Journal of Cell Biology. 187: 655-68. PMID 19951915 DOI: 10.1083/jcb.200908036  0.04
1980 Levy RB, Hansen TH. Functional studies of the products of H-2L locus. Immunogenetics. 10: 7-17. PMID 6967857 DOI: 10.1007/BF01561548  0.039
1995 Jiang PP, Hansen TH, Shreffler DC, Miller RD. Mouse H2 congenic intervals: analysis and use for mapping. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 6: 586-91. PMID 8535063 DOI: 10.1007/BF00352362  0.029
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