Gyongyi Szabo - Publications

Affiliations: 
Semmelweis Egyetem, Hungary 
Area:
Criminology and Penology, Recreation

291 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Osna NA, Tikhanovich I, Ortega-Ribera M, Mueller S, Zheng C, Mueller J, Li S, Sakane S, Weber RCG, Kim HY, Lee W, Ganguly S, Kimura Y, Liu X, Dhar D, ... ... Szabo G, et al. Alcohol-Associated Liver Disease Outcomes: Critical Mechanisms of Liver Injury Progression. Biomolecules. 14. PMID 38672422 DOI: 10.3390/biom14040404  0.339
2024 Taiwo MT, Huang E, Pathak V, Bellar A, Welch N, Dasarathy J, Streem D, McClain CJ, Mitchell MC, Barton BA, Szabo G, Dasarathy S, Schaefer EA, Luther J, Day LZ, et al. Complement protein signatures in patients with alcohol-associated hepatitis. Jci Insight. PMID 38573776 DOI: 10.1172/jci.insight.174127  0.325
2024 Ortega-Ribera M, Zhuang Y, Brezani V, Thevkar Nagesh P, Joshi RS, Babuta M, Wang Y, Szabo G. G-CSF increases calprotectin expression, liver damage and neuroinflammation in a murine model of alcohol-induced ACLF. Frontiers in Cell and Developmental Biology. 12: 1347395. PMID 38419842 DOI: 10.3389/fcell.2024.1347395  0.32
2023 de Carvalho Ribeiro M, Babuta M, Szabo G. Reply: Alcohol-induced extracellular ASC specks perpetuate liver inflammation and damage in alcohol-associated hepatitis even after alcohol cessation. Hepatology (Baltimore, Md.). PMID 37972945 DOI: 10.1097/HEP.0000000000000686  0.362
2023 Mrdjen M, Huang E, Pathak V, Bellar A, Welch N, Dasarathy J, Streem D, McClain CJ, Mitchell M, Radaeva S, Barton B, Szabo G, Dasarathy S, Wang Z, Hazen SL, et al. Dysregulated meta-organismal metabolism of aromatic amino acids in alcohol-associated liver disease. Hepatology Communications. 7. PMID 37820283 DOI: 10.1097/HC9.0000000000000284  0.312
2023 Vatsalya V, Feng W, Kong M, Hu H, Szabo G, McCullough A, Dasarathy S, Nagy LE, Radaeva S, Barton B, Mitchell M, McClain CJ. The Beneficial Effects of Lactobacillus GG Therapy on Liver and Drinking Assessments in Patients with Moderate Alcohol-Associated Hepatitis. The American Journal of Gastroenterology. PMID 37040544 DOI: 10.14309/ajg.0000000000002283  0.312
2023 de Carvalho Ribeiro M, Iracheta-Vellve A, Babuta M, Calenda CD, Copeland C, Zhuang Y, Lowe PP, Hawryluk D, Catalano D, Cho Y, Barton B, Dasarathy S, McClain C, McCullough A, Mitchell M, ... ... Szabo G, et al. Alcohol-induced extracellular asc specks perpetuate liver inflammation and damage in alcoholic hepatitis even after alcohol cessation. Hepatology (Baltimore, Md.). PMID 36862512 DOI: 10.1097/HEP.0000000000000298  0.362
2023 Szabo G, Mitchell M, Dasarathy S, McClain C. Reply: Survival in placebo-treated patients with severe alcoholic hepatitis". Hepatology (Baltimore, Md.). PMID 36815366 DOI: 10.1097/HEP.0000000000000337  0.303
2022 Miyata T, Wu X, Fan X, Huang E, Sanz-Garcia C, Ross CKC, Roychowdhury S, Bellar A, McMullen MR, Dasarathy J, Allende DS, Caballeria J, Sancho-Bru P, McClain CJ, Mitchell M, ... ... Szabo G, et al. Differential role of MLKL in alcohol-associated and non-alcohol-associated fatty liver diseases in mice and humans. Jci Insight. 7. PMID 36477363 DOI: 10.1172/jci.insight.167011  0.332
2022 Ramos A, Joshi RS, Szabo G. Innate immune activation: Parallels in alcohol use disorder and Alzheimer's disease. Frontiers in Molecular Neuroscience. 15: 910298. PMID 36157070 DOI: 10.3389/fnmol.2022.910298  0.319
2022 Cho Y, Bukong TN, Tornai D, Babuta M, Vlachos IS, Kanata E, Catalano D, Szabo G. Neutrophil extracellular traps contribute to liver damage and increase defective low-density neutrophils in alcoholic hepatitis. Journal of Hepatology. PMID 36063965 DOI: 10.1016/j.jhep.2022.08.029  0.361
2022 Cho Y, Joshi R, Lowe P, Copeland C, Ribeiro M, Morel C, Catalano D, Szabo G. Granulocyte colony-stimulating factor attenuates liver damage by M2 macrophage polarization and hepatocyte proliferation in alcoholic hepatitis in mice. Hepatology Communications. PMID 35997009 DOI: 10.1002/hep4.1925  0.35
2022 Morel C, Chowdhary V, Thevkar Nagesh P, Ribeiro M, Hawryluk D, Catalano D, Adorini L, Szabo G. Altered ethanol metabolism and increased oxidative stress enhance alcohol-associated liver injury in farnesoid X receptor-deficient mice. Liver International : Official Journal of the International Association For the Study of the Liver. PMID 35869657 DOI: 10.1111/liv.15374  0.342
2022 Szabo G, Mitchell M, McClain CJ, Dasarathy S, Barton B, McCullough AJ, Nagy LE, Kroll-Desrosiers A, Tornai D, Min HA, Radaeva S, Holbein MEB, Casey L, Cuthbert J. IL-1 receptor antagonist plus pentoxifylline and zinc for severe alcohol-associated hepatitis. Hepatology (Baltimore, Md.). PMID 35340032 DOI: 10.1002/hep.32478  0.307
2022 Osna NA, Eguchi A, Feldstein AE, Tsukamoto H, Dagur RS, Ganesan M, New-Aaron M, Arumugam MK, Chava S, Ribeiro M, Szabo G, Mueller S, Wang S, Chen C, Weinman SA, et al. Cell-to-Cell Communications in Alcohol-Associated Liver Disease. Frontiers in Physiology. 13: 831004. PMID 35264978 DOI: 10.3389/fphys.2022.831004  0.385
2022 Bala S, Babuta M, Catalano D, Saiju A, Szabo G. Alcohol Promotes Exosome Biogenesis and Release Modulating Rabs and miR-192 Expression in Human Hepatocytes. Frontiers in Cell and Developmental Biology. 9: 787356. PMID 35096820 DOI: 10.3389/fcell.2021.787356  0.305
2022 Helsley RN, Miyata T, Kadam A, Venkateshwari V, Sangwan N, Huang EC, Banerjee R, Brown AL, Fung KK, Massey W, Neumann C, Danny O, Osborn LJ, Schugar RC, McMullen MR, ... ... Szabo G, et al. Gut Microbial Trimethylamine is Elevated in Alcohol-Associated Hepatitis and Contributes to Ethanol-Induced Liver Injury in Mice. Elife. 11. PMID 35084335 DOI: 10.7554/eLife.76554  0.321
2021 Babuta M, Szabo G. Extracellular vesicles in inflammation: Focus on the microRNA cargo of EVs in modulation of liver diseases. Journal of Leukocyte Biology. PMID 34755380 DOI: 10.1002/JLB.3MIR0321-156R  0.328
2021 de Carvalho Ribeiro M, Szabo G. Role of the Inflammasome in Liver Disease. Annual Review of Pathology. PMID 34752711 DOI: 10.1146/annurev-pathmechdis-032521-102529  0.321
2021 Miyata T, Wu X, Fan X, Huang E, Sanz-Garcia C, Ross CKC, Roychowdhury S, Bellar A, McMullen MR, Dasarathy J, Allende DS, Caballeria J, Sancho-Bru P, McClain CJ, Mitchell M, ... ... Szabo G, et al. Differential role of MLKL in alcohol-associated and non-alcohol-associated fatty liver diseases in mice and humans. Jci Insight. 6. PMID 33616081 DOI: 10.1172/jci.insight.140180  0.363
2020 Lowe PP, Morel C, Ambade A, Iracheta-Vellve A, Kwiatkowski E, Satishchandran A, Furi I, Cho Y, Gyongyosi B, Catalano D, Lefebvre E, Fischer L, Seyedkazemi S, Schafer DP, Szabo G. Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations. Journal of Neuroinflammation. 17: 296. PMID 33036616 DOI: 10.1186/s12974-020-01972-5  0.352
2020 Tornai D, Szabo G. Emerging medical therapies for severe alcoholic hepatitis. Clinical and Molecular Hepatology. PMID 32981291 DOI: 10.3350/cmh.2020.0145  0.34
2020 Monnig MA, Lamb PS, Parra JM, Cioe PA, Martone CM, Monti PM, Szabo G. Immune Response to an Acute Moderate Dose of Alcohol in Healthy Young Adults. Alcohol and Alcoholism (Oxford, Oxfordshire). PMID 32776108 DOI: 10.1093/Alcalc/Agaa079  0.435
2020 Dasarathy S, Mitchell MC, Barton B, McClain CJ, Szabo G, Nagy LE, Radaeva S, McCullough AJ. Design and rationale of a multicenter defeat alcoholic steatohepatitis trial: (DASH) randomized clinical trial to treat alcohol-associated hepatitis. Contemporary Clinical Trials. 106094. PMID 32739495 DOI: 10.1016/J.Cct.2020.106094  0.392
2020 Fan X, McCullough RL, Huang E, Bellar A, Kim A, Poulsen KL, McClain CJ, Mitchell M, McCullough AJ, Radaeva S, Barton B, Szabo G, Dasarathy S, Rotroff DM, Nagy LE. Diagnostic and Prognostic Significance of Complement in Patients with Alcohol-associated Hepatitis. Hepatology (Baltimore, Md.). PMID 32557728 DOI: 10.1002/Hep.31419  0.468
2020 Osna NA, Bhatia R, Thompson C, Batra SK, Kumar S, Cho Y, Szabo G, Molina PE, Weinman SA, Ganesan M, Kharbanda KK. Role of Non-Genetic Risk Factors in Exacerbating Alcohol-Related Organ Damage. Alcohol (Fayetteville, N.Y.). PMID 32497558 DOI: 10.1016/J.Alcohol.2020.05.002  0.376
2020 Tornai D, Mitchell MC, McClain CJ, Dasarathy S, McCullough A, Radaeva S, Barton BA, Szabo G. 915 90-Day Mortality Prediction Of A Novel Score Based On The Combination Of Il-6, Il-13 And Age Is Superior To Meld Score In Severe Alcoholic Hepatitis Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)33901-9  0.352
2019 Avila MA, Dufour JF, Gerbes AL, Zoulim F, Bataller R, Burra P, Cortez-Pinto H, Gao B, Gilmore I, Mathurin P, Moreno C, Poznyak V, Schnabl B, Szabo G, Thiele M, et al. Recent advances in alcohol-related liver disease (ALD): summary of a Gut round table meeting. Gut. PMID 31879281 DOI: 10.1136/Gutjnl-2019-319720  0.432
2019 Lowe PP, Cho Y, Tornai D, Coban S, Catalano D, Szabo G. Inhibition of the inflammasome signaling cascade reduces alcohol consumption in female but not male mice. Alcoholism, Clinical and Experimental Research. PMID 31854009 DOI: 10.1111/Acer.14272  0.422
2019 Al-Azzawi Y, Albo B, Fasullo M, Coukos J, Watts GJ, Tai R, Radcliffe D, Kroll-Desrosiers A, Devuni D, Szabo G. Sarcopenia is associated with longer hospital stay and multiorgan dysfunction in alcoholic hepatitis. European Journal of Gastroenterology & Hepatology. PMID 31834050 DOI: 10.1097/Meg.0000000000001583  0.434
2019 Vatsalya V, Cave MC, Kong M, Gobejishvili L, Falkner KC, Craycroft J, Mitchell M, Szabo G, McCullough A, Dasarathy S, Radaeva S, Barton B, McClain CJ. Keratin 18 is a Diagnostic and Prognostic Factor for Acute Alcoholic Hepatitis. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 31811953 DOI: 10.1016/J.Cgh.2019.11.050  0.385
2019 Szabo G. Pathogenesis of Acute-on-Chronic Liver Failure in Patients With Infection. Clinical Liver Disease. 14: 103-106. PMID 31632659 DOI: 10.1002/Cld.826  0.323
2019 Crabb DW, Im GY, Szabo G, Mellinger JL, Lucey MR. Diagnosis and Treatment of Alcohol-Related Liver Diseases: 2019 Practice Guidance from the American Association for the Study of Liver Diseases. Hepatology (Baltimore, Md.). PMID 31314133 DOI: 10.1002/Hep.30866  0.412
2019 Lucey MR, Im GY, Mellinger JL, Szabo G, Crabb DW. Introducing the 2019 AASLD guidance on Alcohol-related liver disease. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. PMID 31299131 DOI: 10.1002/Lt.25600  0.41
2019 Fasullo M, Rau P, Liu DQ, Holzwanger E, Mathew JP, Guilarte-Walker Y, Szabo G. Proton pump inhibitors increase the severity of hepatic encephalopathy in cirrhotic patients. World Journal of Hepatology. 11: 522-530. PMID 31293720 DOI: 10.4254/Wjh.V11.I6.522  0.369
2019 Hosseini N, Shor J, Szabo G. Alcoholic Hepatitis: A Review. Alcohol and Alcoholism (Oxford, Oxfordshire). PMID 31219169 DOI: 10.1093/Alcalc/Agz036  0.504
2019 Gyongyosi B, Cho Y, Lowe P, Calenda CD, Iracheta-Vellve A, Satishchandran A, Ambade A, Szabo G. Alcohol-induced IL-17A production in Paneth cells amplifies endoplasmic reticulum stress, apoptosis, and inflammasome-IL-18 activation in the proximal small intestine in mice. Mucosal Immunology. PMID 31105269 DOI: 10.1038/S41385-019-0170-4  0.43
2019 Babuta M, Furi I, Bala S, Bukong TN, Lowe P, Catalano D, Calenda C, Kodys K, Szabo G. Dysregulated autophagy and lysosome function are linked to exosome production via miR-155 in alcoholic liver disease. Hepatology (Baltimore, Md.). PMID 31090940 DOI: 10.1002/Hep.30766  0.452
2019 Saha B, Tornai D, Kodys K, Adejumo A, Lowe P, McClain C, Mitchell M, McCullough A, Srinivasan D, Kroll-Desrosiers A, Barton B, Radaeva S, Szabo G. Biomarkers of macrophage activation and immune danger signals predict clinical outcomes in alcoholic hepatitis. Hepatology (Baltimore, Md.). PMID 30891779 DOI: 10.1002/Hep.30617  0.411
2019 Moreno C, Mueller S, Szabo G. Non-invasive diagnosis and biomarkers in alcohol-related liver disease. Journal of Hepatology. 70: 273-283. PMID 30658728 DOI: 10.1016/J.Jhep.2018.11.025  0.373
2019 Szabo G, Kamath PS, Shah VH, Thursz M, Mathurin P. Alcohol-Related Liver Disease: Areas of Consensus, Unmet Needs and Opportunities for Further Study. Hepatology (Baltimore, Md.). PMID 30645002 DOI: 10.1002/Hep.30369  0.43
2019 Tornai D, Furi I, Shen ZT, Sigalov AB, Coban S, Szabo G. Inhibition of Triggering Receptor Expressed on Myeloid Cells 1 Ameliorates Inflammation and Macrophage and Neutrophil Activation in Alcoholic Liver Disease in Mice. Hepatology Communications. 3: 99-115. PMID 30619998 DOI: 10.1002/hep4.1269  0.399
2019 Cho Y, Lowe P, Gyöngyösi B, Calenda CD, Iracheta-Vellve A, Satishchandran A, Ambade A, Szabo G. Sa1500 – Alcohol Induced Il-17A Production in Paneth Cells Amplifies Endoplasmic Reticulum Stress and Inflammasome-Il-18 Activation in the Proximal Small Intestine in Mice Gastroenterology. 156. DOI: 10.1016/S0016-5085(19)40050-4  0.347
2018 Thursz M, Kamath PS, Mathurin P, Szabo G, Shah VH. Alcohol-related Liver Disease: Areas of Consensus, Unmet Needs and Opportunities for Further Study. Journal of Hepatology. PMID 30658117 DOI: 10.1016/J.Jhep.2018.10.041  0.437
2018 Bala S, Szabo G. TFEB, a master regulator of lysosome biogenesis and autophagy, is a new player in alcoholic liver disease. Digestive Medicine Research. 1. PMID 30450489 DOI: 10.21037/dmr.2018.09.03  0.334
2018 Iracheta-Vellve A, Calenda CD, Petrasek J, Ambade A, Kodys K, Adorini L, Szabo G. FXR and TGR5 Agonists Ameliorate Liver Injury, Steatosis, and Inflammation After Binge or Prolonged Alcohol Feeding in Mice. Hepatology Communications. 2: 1379-1391. PMID 30411084 DOI: 10.1002/hep4.1256  0.328
2018 Lowe PP, Gyongyosi B, Satishchandran A, Iracheta-Vellve A, Cho Y, Ambade A, Szabo G. Reduced gut microbiome protects from alcohol-induced neuroinflammation and alters intestinal and brain inflammasome expression. Journal of Neuroinflammation. 15: 298. PMID 30368255 DOI: 10.1186/S12974-018-1328-9  0.444
2018 Szabo G. Alcoholic Liver Disease Accelerates Early Hepatocellular Cancer in a Mouse Model. Advances in Experimental Medicine and Biology. 1032: 71-79. PMID 30362091 DOI: 10.1007/978-3-319-98788-0_5  0.417
2018 Ambade A, Lowe P, Kodys K, Catalano D, Gyongyosi B, Cho Y, Iracheta Vellve A, Adejumo A, Saha B, Calenda C, Mehta J, Lefebvre E, Vig P, Szabo G. Pharmacological inhibition of CCR2/5 signaling prevents and reverses alcohol-induced liver damage, steatosis and inflammation in mice. Hepatology (Baltimore, Md.). PMID 30179264 DOI: 10.1002/Hep.30249  0.504
2018 Seitz HK, Bataller R, Cortez-Pinto H, Gao B, Gual A, Lackner C, Mathurin P, Mueller S, Szabo G, Tsukamoto H. Alcoholic liver disease. Nature Reviews. Disease Primers. 4: 16. PMID 30115921 DOI: 10.1038/s41572-018-0014-7  0.377
2018 Wang X, Ribeiro M, Iracheta-Vellve A, Lowe P, Ambade A, Satishchandran A, Bukong T, Catalano D, Kodys K, Szabo G. Macrophage-specific HIF-1α contributes to impaired autophagic flux in non-alcoholic steatohepatitis. Hepatology (Baltimore, Md.). PMID 30102772 DOI: 10.1002/Hep.30215  0.38
2018 Bukong TN, Cho Y, Iracheta-Vellve A, Saha B, Lowe P, Adejumo A, Furi I, Ambade A, Gyongyosi B, Catalano D, Kodys K, Szabo G. Abnormal neutrophil traps and impaired efferocytosis contribute to liver injury and sepsis severity after binge alcohol use. Journal of Hepatology. PMID 30030149 DOI: 10.1016/J.Jhep.2018.07.005  0.429
2018 Szabo G. More than meets the eye: Severe alcoholic hepatitis can present as acute-on-chronic liver failure. Journal of Hepatology. PMID 29935965 DOI: 10.1016/J.Jhep.2018.05.031  0.418
2018 Bajaj JS, Moreau R, Kamath PS, Vargas HE, Arroyo V, Reddy KR, Szabo G, Tandon P, Olson J, Karvellas C, Gustot T, Lai JC, Wong F. Acute-on-Chronic Liver Failure: Getting ready for prime-time. Hepatology (Baltimore, Md.). PMID 29689120 DOI: 10.1002/Hep.30056  0.339
2018 Szabo G. Commentary on "Intestinal fungi contribute to development of alcoholic liver disease" Yang et al, J Clin Invest 127:2829-2841 (2017). Hepatology (Baltimore, Md.). PMID 29684245 DOI: 10.1002/Hep.30055  0.373
2018 Szabo G. Women and alcoholic liver disease - warning of a silent danger. Nature Reviews. Gastroenterology & Hepatology. PMID 29443115 DOI: 10.1038/Nrgastro.2018.8  0.42
2018 Al-azzawi Y, Coukos J, Martin A, Albo B, Howard-Wilson SR, Alsayid M, Kroll-Desrosiers A, Devuni D, Barton B, Szabo G. Obesity and Its Correlation With Severe Alcoholic Hepatitis: 906 The American Journal of Gastroenterology. 113. DOI: 10.14309/00000434-201810001-00906  0.381
2018 AL-Azzawi Y, Coukos J, Martin A, Albo B, Howard-Wilson SR, Kroll-Desrosiers A, Radcliffe D, Tai R, Watts G, Szabo G. Sarcopenia Is Increased in Females and Associated With Severity of Alcoholic Hepatitis and Increased Hospital Stay: 905 The American Journal of Gastroenterology. 113. DOI: 10.14309/00000434-201810001-00905  0.382
2018 Yasiralazzawi Y, Al-Abboodi Y, Devuni D, Szabo G. The correlation of obesity with morbidity and mortality in alcoholic hepatitis Journal of Hepatology. 68. DOI: 10.1016/S0168-8278(18)31899-3  0.359
2017 Szabo G. Clinical Trial Design for Alcoholic Hepatitis. Seminars in Liver Disease. 37: 332-342. PMID 29272895 DOI: 10.1055/S-0037-1608788  0.332
2017 Saha B, Momen-Heravi F, Furi I, Kodys K, Catalano D, Gangopadhyay A, Haraszti R, Satishchandran A, Iracheta-Vellve A, Adejumo A, Shaffer SA, Szabo G. Extracellular vesicles from mice with alcoholic liver disease carry a distinct protein cargo and induce macrophage activation via Hsp90. Hepatology (Baltimore, Md.). PMID 29251792 DOI: 10.1002/Hep.29732  0.405
2017 Satishchandran A, Ambade A, Rao S, Hsueh YC, Iracheta-Vellve A, Tornai D, Lowe P, Gyongyosi B, Li J, Catalano D, Zhong L, Kodys K, Xie J, Bala S, Gao G, ... Szabo G, et al. MicroRNA 122, Regulated by GRLH2, Protects Livers of Mice and Patients from Ethanol-induced Liver Disease. Gastroenterology. PMID 28987423 DOI: 10.1053/J.Gastro.2017.09.022  0.458
2017 Gustot T, Fernandez J, Szabo G, Albillos A, Louvet A, Jalan R, Moreau R, Moreno C. Sepsis in Alcohol-related Liver Disease. Journal of Hepatology. PMID 28647569 DOI: 10.1016/J.Jhep.2017.06.013  0.437
2017 Szabo G, Momen-Heravi F. Extracellular vesicles in liver disease and potential as biomarkers and therapeutic targets. Nature Reviews. Gastroenterology & Hepatology. PMID 28634412 DOI: 10.1038/Nrgastro.2017.71  0.396
2017 Bala S, Csak T, Kodys K, Catalano D, Ambade A, Furi I, Lowe P, Cho Y, Iracheta-Vellve A, Szabo G. Alcohol-induced miR-155 and HDAC11 inhibit negative regulators of the TLR4 pathway and lead to increased LPS responsiveness of Kupffer cells in alcoholic liver disease. Journal of Leukocyte Biology. PMID 28584078 DOI: 10.1189/Jlb.3A0716-310R  0.43
2017 Lowe PP, Gyongyosi B, Satishchandran A, Iracheta-Vellve A, Ambade A, Cho Y, Kodys K, Catalano D, Ward DV, Szabo G. Correction: Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice. Plos One. 12: e0179070. PMID 28562651 DOI: 10.1371/journal.pone.0179070  0.314
2017 Grander C, Adolph TE, Wieser V, Lowe P, Wrzosek L, Gyongyosi B, Ward DV, Grabherr F, Gerner RR, Pfister A, Enrich B, Ciocan D, Macheiner S, Mayr L, Drach M, ... ... Szabo G, et al. Recovery of ethanol-induced Akkermansia muciniphila depletion ameliorates alcoholic liver disease. Gut. PMID 28550049 DOI: 10.1136/Gutjnl-2016-313432  0.429
2017 Szabo G, Petrasek J. Gut-liver axis and sterile signals in the development of alcoholic liver disease. Alcohol and Alcoholism (Oxford, Oxfordshire). 1-11. PMID 28482064 DOI: 10.1093/Alcalc/Agx025  0.482
2017 Lowe PP, Gyongyosi B, Satishchandran A, Iracheta-Vellve A, Ambade A, Kodys K, Catalano D, Ward DV, Szabo G. Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice. Plos One. 12: e0174544. PMID 28350851 DOI: 10.1371/Journal.Pone.0174544  0.467
2017 Iracheta-Vellve A, Petrasek J, Gyogyosi B, Bala S, Csak T, Kodys K, Szabo G. Interleukin-1 inhibition facilitates recovery from liver injury and promotes regeneration of hepatocytes in alcoholic hepatitis in mice. Liver International : Official Journal of the International Association For the Study of the Liver. PMID 28345165 DOI: 10.1111/Liv.13430  0.486
2017 Saha B, Kodys K, Adejumo A, Szabo G. Circulating and Exosome-Packaged Hepatitis C Single-Stranded RNA Induce Monocyte Differentiation via TLR7/8 to Polarized Macrophages and Fibrocytes. Journal of Immunology (Baltimore, Md. : 1950). PMID 28122964 DOI: 10.4049/Jimmunol.1600797  0.351
2017 Al-Azzawi Y, Al-Abboodi Y, Asrani S, Devauni D, Szabo G. Obesity Is a Risk Factor for Mortality and Organ Failure in Alcoholic Hepatitis: 889 The American Journal of Gastroenterology. 112. DOI: 10.14309/00000434-201710001-00890  0.35
2017 Szabo G. S20-4Alcohol Increases Circulating Exosomes And Exosomes From Hepatitis C Infected Patients Transmit Hcv Infection Alcohol and Alcoholism. 52. DOI: 10.1093/Alcalc/Agx075.78  0.374
2017 Grander C, Grabherr F, Adolph TE, Perlemuter G, Szabo G, Cassard AM, Tilg H. Ethanol-induced depletion of Akkermansia muciniphila drives alcoholic liver disease Journal of Hepatology. 66. DOI: 10.1016/S0168-8278(17)31027-9  0.437
2017 Bukong TN, Saha B, Iracheta-Vellve A, Adejumo AC, Furi I, Ambade A, Gyongyosi B, Lowe P, Catalano D, Kodys K, Szabo G. Reduced Neutrophil Extracellular Trap Formation and their Impaired Clearance by Macrophages Exacerbates Liver Injury in Alcoholic Liver Disease Gastroenterology. 152: S1111. DOI: 10.1016/S0016-5085(17)33743-5  0.459
2017 Szabo G, Lippai D, Bala S. NLRP3/ASC inflammasome activation and micro-RNA-155 contribute to alcohol-induced neuroinflammation Alcohol. 60: 221. DOI: 10.1016/J.Alcohol.2017.02.261  0.373
2016 Saha B, Kodys K, Szabo G. Hepatitis C Virus-Induced Monocyte Differentiation Into Polarized M2 Macrophages Promotes Stellate Cell Activation via TGF-β. Cellular and Molecular Gastroenterology and Hepatology. 2: 302-316.e8. PMID 28090562 DOI: 10.1016/J.Jcmgh.2015.12.005  0.4
2016 Ambade A, Satishchandran A, Saha B, Gyongyosi B, Lowe P, Kodys K, Catalano D, Szabo G. Hepatocellular carcinoma is accelerated by NASH involving M2 macrophage polarization mediated by hif-1αinduced IL-10. Oncoimmunology. 5: e1221557. PMID 27853646 DOI: 10.1080/2162402X.2016.1221557  0.356
2016 Iracheta-Vellve A, Petrasek J, Gyongyosi B, Satishchandran A, Lowe P, Kodys K, Catalano D, Calenda CD, Kurt-Jones EA, Fitzgerald KA, Szabo G. Endoplasmic reticulum stress-induced hepatocellular death pathways mediate liver injury and fibrosis via Stimulator of Interferon Genes. The Journal of Biological Chemistry. PMID 27810900 DOI: 10.1074/Jbc.M116.736991  0.432
2016 Bukong TN, Iracheta-Vellve A, Saha B, Ambade A, Satishchandran A, Gyongyosi B, Lowe P, Catalano D, Kodys K, Szabo G. Inhibition of spleen tyrosine kinase activation ameliorates inflammation, cell death, and steatosis in alcoholic liver disease. Hepatology (Baltimore, Md.). PMID 27302565 DOI: 10.1002/Hep.28680  0.507
2016 Bukong TN, Iracheta-Vellve A, Gyongyosi B, Ambade A, Catalano D, Kodys K, Szabo G. Therapeutic Benefits of Spleen Tyrosine Kinase Inhibitor Administration on Binge Drinking-Induced Alcoholic Liver Injury, Steatosis, and Inflammation in Mice. Alcoholism, Clinical and Experimental Research. PMID 27177528 DOI: 10.1111/Acer.13096  0.481
2016 Ambade A, Satishchandran A, Gyongyosi B, Lowe P, Szabo G. Adult mouse model of early hepatocellular carcinoma promoted by alcoholic liver disease. World Journal of Gastroenterology. 22: 4091-108. PMID 27122661 DOI: 10.3748/Wjg.V22.I16.4091  0.418
2016 Crabb DW, Bataller R, Chalasani NP, Kamath PS, Lucey M, Mathurin P, McClain C, McCullough A, Mitchell MC, Morgan TR, Nagy L, Radaeva S, Sanyal A, Shah V, Szabo G, et al. Standard Definitions and Common Data Elements for Clinical Trials in Patients With Alcoholic Hepatitis: Recommendation From the NIAAA Alcoholic Hepatitis Consortia. Gastroenterology. PMID 26921783 DOI: 10.1053/J.Gastro.2016.02.042  0.405
2016 Ambade A, Satishchandran A, Szabo G. Alcoholic hepatitis accelerates early hepatobiliary cancer by increasing stemness and miR-122-mediated HIF-1α activation. Scientific Reports. 6: 21340. PMID 26888602 DOI: 10.1038/Srep21340  0.456
2016 Bala S, Csak T, Saha B, Zatsiorsky J, Kodys K, Catalano D, Szabo G. The pro-inflammatory effects of miR-155 promote liver fibrosis and alcohol-induced steatohepatitis. Journal of Hepatology. PMID 26867493 DOI: 10.1016/J.Jhep.2016.01.035  0.438
2016 Tilg H, Moschen AR, Szabo G. Interleukin-1 and inflammasomes in ALD/AAH and NAFLD/NASH. Hepatology (Baltimore, Md.). PMID 26773297 DOI: 10.1002/Hep.28456  0.458
2016 Iracheta-Vellve A, Petrasek J, Ambade A, Kodys K, Adorini L, Szabo G. Sa1657 FXR and/or TGR5 Bile Acid Receptor Agonists Differently Ameliorate Liver Injury and Steatosis After Acute Binge or Prolonged Alcohol Feeding in Mice Gastroenterology. 150: S1088. DOI: 10.1016/S0016-5085(16)33671-X  0.423
2016 Saha B, Adejumo AC, Kodys K, Lowe P, Catalano D, Giansiracusa D, Vo T, Kroll-Desrosiers A, Barton BA, Nieto N, McCullough A, Nagy L, McClain CJ, Mitchell M, Szabo G. Sa1654 MELD Scores Correlate With Survival and Circulating Markers of Microbial Translocation, Danger Signals, and Inflammatory Markers: sCD163 Predicts Survival in Patients With Alcoholic Hepatitis Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)33668-X  0.379
2016 Satishchandran A, Ambade A, Rao S, Hsueh Y, Gyongyosi B, Lowe P, Mehta N, Zatsiorsky J, Iracheta-Vellve A, Li J, Xie J, Zhong L, Catalano D, Saha B, Kodys K, ... ... Szabo G, et al. 655 Grainyhead-Like 2, a Novel Hepatic Transcription Factor, Promotes Alcohol-induced Liver Injury, Steatosis and Inflammation via miR-122 Down-regulation Gastroenterology. 150: S1044. DOI: 10.1016/S0016-5085(16)33527-2  0.434
2015 Szabo G, Saha B. Alcohol's Effect on Host Defense. Alcohol Research : Current Reviews. 37: 159-70. PMID 26695755  0.343
2015 Saha B, Momen-Heravi F, Kodys K, Szabo G. MicroRNA Cargo of Extracellular Vesicles from Alcohol-Exposed Monocytes Signals Naïve Monocytes to Differentiate into M2 Macrophages. The Journal of Biological Chemistry. PMID 26527689 DOI: 10.1074/Jbc.M115.694133  0.407
2015 Momen-Heravi F, Saha B, Kodys K, Catalano D, Satishchandran A, Szabo G. Increased number of circulating exosomes and their microRNA cargos are potential novel biomarkers in alcoholic hepatitis. Journal of Translational Medicine. 13: 261. PMID 26264599 DOI: 10.1186/S12967-015-0623-9  0.415
2015 Szabo G, Iracheta-Vellve A. Inflammasome activation in the liver: Focus on alcoholic and non-alcoholic steatohepatitis. Clinics and Research in Hepatology and Gastroenterology. 39: S18-23. PMID 26216030 DOI: 10.1016/J.Clinre.2015.06.012  0.475
2015 Iracheta-Vellve A, Petrasek J, Satishchandran A, Gyongyosi B, Saha B, Kodys K, Fitzgerald KA, Kurt-Jones EA, Szabo G. Inhibition of sterile danger signals, uric acid and ATP, prevents inflammasome activation and protects from alcoholic steatohepatitis in mice. Journal of Hepatology. 63: 1147-55. PMID 26100496 DOI: 10.1016/J.Jhep.2015.06.013  0.41
2015 Ganz M, Bukong TN, Csak T, Saha B, Park JK, Ambade A, Kodys K, Szabo G. Progression of non-alcoholic steatosis to steatohepatitis and fibrosis parallels cumulative accumulation of danger signals that promote inflammation and liver tumors in a high fat-cholesterol-sugar diet model in mice. Journal of Translational Medicine. 13: 193. PMID 26077675 DOI: 10.1186/S12967-015-0552-7  0.459
2015 Szabo G, Petrasek J. Inflammasome activation and function in liver disease. Nature Reviews. Gastroenterology & Hepatology. 12: 387-400. PMID 26055245 DOI: 10.1038/Nrgastro.2015.94  0.464
2015 Csak T, Bala S, Lippai D, Kodys K, Catalano D, Iracheta-Vellve A, Szabo G. MicroRNA-155 Deficiency Attenuates Liver Steatosis and Fibrosis without Reducing Inflammation in a Mouse Model of Steatohepatitis. Plos One. 10: e0129251. PMID 26042593 DOI: 10.1371/Journal.Pone.0129251  0.348
2015 Sanyal AJ, Gao B, Szabo G. Gaps in Knowledge and Research Priorities for Alcoholic Hepatitis. Gastroenterology. 149: 4-9. PMID 26008859 DOI: 10.1053/J.Gastro.2015.05.015  0.409
2015 Momen-Heravi F, Bala S, Kodys K, Szabo G. Exosomes derived from alcohol-treated hepatocytes horizontally transfer liver specific miRNA-122 and sensitize monocytes to LPS. Scientific Reports. 5: 9991. PMID 25973575 DOI: 10.1038/Srep09991  0.412
2015 Petrasek J, Iracheta-Vellve A, Saha B, Satishchandran A, Kodys K, Fitzgerald KA, Kurt-Jones EA, Szabo G. Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease. Journal of Leukocyte Biology. 98: 249-56. PMID 25934928 DOI: 10.1189/Jlb.3Ab1214-590R  0.47
2015 Punzalan CS, Bukong TN, Szabo G. Alcoholic hepatitis and HCV interactions in the modulation of liver disease. Journal of Viral Hepatitis. 22: 769-76. PMID 25754333 DOI: 10.1111/Jvh.12399  0.463
2015 Saha B, Bala S, Hosseini N, Kodys K, Szabo G. Krüppel-like factor 4 is a transcriptional regulator of M1/M2 macrophage polarization in alcoholic liver disease. Journal of Leukocyte Biology. PMID 25740962 DOI: 10.1189/Jlb.4A1014-485R  0.372
2015 Saha B, Bruneau JC, Kodys K, Szabo G. Alcohol-induced miR-27a regulates differentiation and M2 macrophage polarization of normal human monocytes. Journal of Immunology (Baltimore, Md. : 1950). 194: 3079-87. PMID 25716995 DOI: 10.4049/Jimmunol.1402190  0.45
2015 Szabo G, Satishchandran A. MicroRNAs in alcoholic liver disease. Seminars in Liver Disease. 35: 36-42. PMID 25632933 DOI: 10.1055/S-0034-1397347  0.407
2015 Kolls JK, Szabo G. The genetics of hepatitis C virus underlie its ability to escape humoral immunity. The Journal of Clinical Investigation. 125: 97-8. PMID 25500881 DOI: 10.1172/Jci79424  0.309
2015 Szabo G. Gut-liver axis in alcoholic liver disease. Gastroenterology. 148: 30-6. PMID 25447847 DOI: 10.1053/J.Gastro.2014.10.042  0.485
2015 Szabo G, Saha B, Bukong TN. Alcohol and HCV: implications for liver cancer. Advances in Experimental Medicine and Biology. 815: 197-216. PMID 25427909 DOI: 10.1007/978-3-319-09614-8_12  0.427
2015 Csak T, Bala S, Lippai D, Satishchandran A, Catalano D, Kodys K, Szabo G. microRNA-122 regulates hypoxia-inducible factor-1 and vimentin in hepatocytes and correlates with fibrosis in diet-induced steatohepatitis. Liver International : Official Journal of the International Association For the Study of the Liver. 35: 532-41. PMID 25040043 DOI: 10.1111/Liv.12633  0.375
2015 Lowe PP, Gyongyosi B, Szabo G. P-15GUT BACTERIAL LOAD INFLUENCES LIVER INFLAMMATION AND NEUTROPHIL INFILTRATION IN AN ACUTE-ON-CHRONIC ALCOHOL FEEDING MODEL IN MICE Alcohol and Alcoholism. 50: i48.4-i49. DOI: 10.1093/Alcalc/Agv080.15  0.474
2015 Bala S, Momen-heravi F, Csak T, Catalano D, Szabo G, Li K. Sa1875 Therapeutic Inhibition of miRNA-132 Attenuates CCL4-Induced Liver Fibrosis Gastroenterology. 148: S-1031. DOI: 10.1016/S0016-5085(15)33527-7  0.307
2014 Szabo G, Lippai D. Converging actions of alcohol on liver and brain immune signaling. International Review of Neurobiology. 118: 359-80. PMID 25175869 DOI: 10.1016/B978-0-12-801284-0.00011-7  0.463
2014 Lippai D, Bala S, Catalano D, Kodys K, Szabo G. Micro-RNA-155 deficiency prevents alcohol-induced serum endotoxin increase and small bowel inflammation in mice. Alcoholism, Clinical and Experimental Research. 38: 2217-24. PMID 25156614 DOI: 10.1111/Acer.12483  0.431
2014 Ganz M, Csak T, Szabo G. High fat diet feeding results in gender specific steatohepatitis and inflammasome activation. World Journal of Gastroenterology. 20: 8525-34. PMID 25024607 DOI: 10.3748/Wjg.V20.I26.8525  0.343
2014 Saha B, Szabo G. Innate immune cell networking in hepatitis C virus infection. Journal of Leukocyte Biology. 96: 757-66. PMID 25001860 DOI: 10.1189/Jlb.4Mr0314-141R  0.315
2014 Bala S, Marcos M, Gattu A, Catalano D, Szabo G. Acute binge drinking increases serum endotoxin and bacterial DNA levels in healthy individuals. Plos One. 9: e96864. PMID 24828436 DOI: 10.1371/Journal.Pone.0096864  0.436
2014 Csak T, Pillai A, Ganz M, Lippai D, Petrasek J, Park JK, Kodys K, Dolganiuc A, Kurt-Jones EA, Szabo G. Both bone marrow-derived and non-bone marrow-derived cells contribute to AIM2 and NLRP3 inflammasome activation in a MyD88-dependent manner in dietary steatohepatitis. Liver International : Official Journal of the International Association For the Study of the Liver. 34: 1402-13. PMID 24650018 DOI: 10.1111/Liv.12537  0.386
2013 Ganz M, Szabo G. Immune and inflammatory pathways in NASH. Hepatology International. 7: 771-81. PMID 24587847 DOI: 10.1007/S12072-013-9468-6  0.414
2013 Petrasek J, Iracheta-Vellve A, Csak T, Satishchandran A, Kodys K, Kurt-Jones EA, Fitzgerald KA, Szabo G. STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease. Proceedings of the National Academy of Sciences of the United States of America. 110: 16544-9. PMID 24052526 DOI: 10.1073/Pnas.1308331110  0.397
2013 Lippai D, Bala S, Csak T, Kurt-Jones EA, Szabo G. Chronic alcohol-induced microRNA-155 contributes to neuroinflammation in a TLR4-dependent manner in mice. Plos One. 8: e70945. PMID 23951048 DOI: 10.1371/Journal.Pone.0070945  0.467
2013 Petrasek J, Csak T, Ganz M, Szabo G. Differences in innate immune signaling between alcoholic and non-alcoholic steatohepatitis. Journal of Gastroenterology and Hepatology. 28: 93-8. PMID 23855302 DOI: 10.1111/Jgh.12020  0.437
2013 Bukong TN, Kodys K, Szabo G. Human ezrin-moesin-radixin proteins modulate hepatitis C virus infection. Hepatology (Baltimore, Md.). 58: 1569-79. PMID 23703860 DOI: 10.1002/Hep.26500  0.3
2013 Szabo G, Bala S. MicroRNAs in liver disease. Nature Reviews. Gastroenterology & Hepatology. 10: 542-52. PMID 23689081 DOI: 10.1038/Nrgastro.2013.87  0.341
2013 Zhang S, Saha B, Kodys K, Szabo G. IFN-γ production by human natural killer cells in response to HCV-infected hepatoma cells is dependent on accessory cells. Journal of Hepatology. 59: 442-9. PMID 23665181 DOI: 10.1016/J.Jhep.2013.04.022  0.331
2013 Lippai D, Bala S, Petrasek J, Csak T, Levin I, Kurt-Jones EA, Szabo G. Alcohol-induced IL-1β in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation. Journal of Leukocyte Biology. 94: 171-82. PMID 23625200 DOI: 10.1189/Jlb.1212659  0.414
2013 Petrasek J, Csak T, Szabo G. Toll-like receptors in liver disease. Advances in Clinical Chemistry. 59: 155-201. PMID 23461136 DOI: 10.1016/B978-0-12-405211-6.00006-1  0.479
2013 Shukla SD, Pruett SB, Szabo G, Arteel GE. Binge ethanol and liver: new molecular developments. Alcoholism, Clinical and Experimental Research. 37: 550-7. PMID 23347137 DOI: 10.1111/Acer.12011  0.44
2013 Hou W, Bukong TN, Kodys K, Szabo G. Alcohol facilitates HCV RNA replication via up-regulation of miR-122 expression and inhibition of cyclin G1 in human hepatoma cells. Alcoholism, Clinical and Experimental Research. 37: 599-608. PMID 23126531 DOI: 10.1111/Acer.12005  0.399
2013 Zhang S, Kodys K, Li K, Szabo G. Human type 2 myeloid dendritic cells produce interferon-λ and amplify interferon-α in response to hepatitis C virus infection. Gastroenterology. 144: 414-425.e7. PMID 23089201 DOI: 10.1053/J.Gastro.2012.10.034  0.353
2013 Bukong TN, Hou W, Kodys K, Szabo G. Ethanol facilitates hepatitis C virus replication via up-regulation of GW182 and heat shock protein 90 in human hepatoma cells. Hepatology (Baltimore, Md.). 57: 70-80. PMID 22898980 DOI: 10.1002/Hep.26010  0.339
2013 Zhang S, Kodys K, Babcock GJ, Szabo G. CD81/CD9 tetraspanins aid plasmacytoid dendritic cells in recognition of hepatitis C virus-infected cells and induction of interferon-alpha. Hepatology (Baltimore, Md.). 58: 940-9. PMID 22577054 DOI: 10.1002/Hep.25827  0.325
2013 Szabo G, Dooley S, Mueller S, Seitz H, Bataller R, Sanyal A, Caravati C. S04 * ALCOHOLIC HEPATITIS ESBRA & NIAAA JOINT SYMPOSIUM Alcohol and Alcoholism. 48: i5-i7. DOI: 10.1093/Alcalc/Agt077  0.42
2013 Petrasek J, Bala S, Kodys K, Menashy V, Barrieau M, Kurt-Jones EA, Szabo G. 209 Uric Acid-Activated NLRP3 Inflammasome Is a Therapeutic Target in Alcoholic Liver Disease Gastroenterology. 144. DOI: 10.1016/S0016-5085(13)63490-3  0.426
2013 Satishchandran A, Bala S, Szabo G. The role of miR-122 in the pathogenesis of chronic alcoholic liver disease Alcohol. 47: 574. DOI: 10.1016/J.Alcohol.2013.09.032  0.402
2013 Saha B, Bruneau J, Szabo G. Alcohol and hepatitis C virus infection modulates monocytes to macrophage differentiation Alcohol. 47: 574. DOI: 10.1016/J.Alcohol.2013.09.030  0.423
2013 Bala S, Csak T, Zatsiorsky J, Catalano D, Kodys K, Szabo G. Role of microRNA-155 in alcoholic liver disease Alcohol. 47: 568. DOI: 10.1016/J.Alcohol.2013.09.006  0.454
2012 Szabo G, Petrasek J, Bala S. Innate immunity and alcoholic liver disease. Digestive Diseases (Basel, Switzerland). 30: 55-60. PMID 23075869 DOI: 10.1159/000341126  0.466
2012 Dolganiuc A, Kodys K, Marshall C, Saha B, Zhang S, Bala S, Szabo G. Type III interferons, IL-28 and IL-29, are increased in chronic HCV infection and induce myeloid dendritic cell-mediated FoxP3+ regulatory T cells. Plos One. 7: e44915. PMID 23071503 DOI: 10.1371/Journal.Pone.0044915  0.322
2012 Petrasek J, Bala S, Csak T, Lippai D, Kodys K, Menashy V, Barrieau M, Min SY, Kurt-Jones EA, Szabo G. IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice. The Journal of Clinical Investigation. 122: 3476-89. PMID 22945633 DOI: 10.1172/Jci60777  0.349
2012 Bala S, Tilahun Y, Taha O, Alao H, Kodys K, Catalano D, Szabo G. Increased microRNA-155 expression in the serum and peripheral monocytes in chronic HCV infection. Journal of Translational Medicine. 10: 151. PMID 22846613 DOI: 10.1186/1479-5876-10-151  0.385
2012 Bala S, Tang A, Catalano D, Petrasek J, Taha O, Kodys K, Szabo G. Induction of Bcl-3 by acute binge alcohol results in toll-like receptor 4/LPS tolerance. Journal of Leukocyte Biology. 92: 611-20. PMID 22782967 DOI: 10.1189/Jlb.0112050  0.447
2012 Szabo G, Lippai D. Molecular hepatic carcinogenesis: impact of inflammation. Digestive Diseases (Basel, Switzerland). 30: 243-8. PMID 22722548 DOI: 10.1159/000336913  0.358
2012 Morishima C, Shiffman ML, Dienstag JL, Lindsay KL, Szabo G, Everson GT, Lok AS, Di Bisceglie AM, Ghany MG, Naishadham D, Morgan TR, Wright EC. Reduction in Hepatic Inflammation Is Associated With Less Fibrosis Progression and Fewer Clinical Outcomes in Advanced Hepatitis C. The American Journal of Gastroenterology. PMID 22688849 DOI: 10.1038/Ajg.2012.137  0.349
2012 Bala S, Petrasek J, Mundkur S, Catalano D, Levin I, Ward J, Alao H, Kodys K, Szabo G. Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases. Hepatology (Baltimore, Md.). 56: 1946-57. PMID 22684891 DOI: 10.1002/Hep.25873  0.417
2012 Szabo G, Csak T. Inflammasomes in liver diseases. Journal of Hepatology. 57: 642-54. PMID 22634126 DOI: 10.1016/J.Jhep.2012.03.035  0.417
2012 Bala S, Szabo G. MicroRNA Signature in Alcoholic Liver Disease. International Journal of Hepatology. 2012: 498232. PMID 22518321 DOI: 10.1155/2012/498232  0.431
2012 Szabo G, Sarnow P, Bala S. MicroRNA silencing and the development of novel therapies for liver disease. Journal of Hepatology. 57: 462-6. PMID 22504335 DOI: 10.1016/J.Jhep.2012.01.030  0.33
2012 Levin I, Petrasek J, Szabo G. The presence of p47phox in liver parenchymal cells is a key mediator in the pathogenesis of alcoholic liver steatosis. Alcoholism, Clinical and Experimental Research. 36: 1397-406. PMID 22376231 DOI: 10.1111/J.1530-0277.2012.01739.X  0.423
2012 Bukong TN, Lo T, Szabo G, Dolganiuc A. Novel developmental biology-based protocol of embryonic stem cell differentiation to morphologically sound and functional yet immature hepatocytes. Liver International : Official Journal of the International Association For the Study of the Liver. 32: 732-41. PMID 22292891 DOI: 10.1111/J.1478-3231.2011.02743.X  0.326
2012 Nath B, Szabo G. Hypoxia and hypoxia inducible factors: Diverse roles in liver diseases Hepatology. 55: 622-633. PMID 22120903 DOI: 10.1002/Hep.25497  0.385
2012 Csak T, Villai A, Ganz M, Lippai D, Petrasek J, Nath B, Kodys K, Dolganiuc A, Kurt-Jones E, Szabo G. NALP3 inflammasome activation is MYD88-, but not TLR4-dependent and involves both parenchymal and bone marrow derived cells in non-alcoholic steatohepatitis (NASH) Zeitschrift FüR Gastroenterologie. 50. DOI: 10.1055/S-0032-1312444  0.386
2012 Csak T, Bala S, Lippai D, Szabo G. 691 Cell-Specific Roles of miR-155 and miR-122 in Inflammation, Immunity and Fibrosis in Non-Alcoholic Steatohepatitis Gastroenterology. 142: S-921. DOI: 10.1016/S0016-5085(12)63574-4  0.358
2012 Petrasek J, Bala S, Lippai D, Kodys K, Menashy V, Barrieau M, Kurt-Jones EA, Szabo G. 293 Inflammasome Complex Components, ASC and Caspase-1, Mediate Alcoholic Steatohepatitis via Interleukin-1 in Mice Gastroenterology. 142: S-910. DOI: 10.1016/S0016-5085(12)63533-1  0.38
2011 Ganz M, Csak T, Nath B, Szabo G. Lipopolysaccharide induces and activates the Nalp3 inflammasome in the liver World Journal of Gastroenterology. 17: 4772-4778. PMID 22147977 DOI: 10.3748/Wjg.V17.I43.4772  0.399
2011 Pang M, Bala S, Kodys K, Catalano D, Szabo G. Inhibition of TLR8- and TLR4-induced Type I IFN induction by alcohol is different from its effects on inflammatory cytokine production in monocytes. Bmc Immunology. 12: 55. PMID 21962237 DOI: 10.1186/1471-2172-12-55  0.475
2011 Mandrekar P, Ambade A, Lim A, Szabo G, Catalano D. An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: regulation of proinflammatory cytokines and hepatic steatosis in mice. Hepatology (Baltimore, Md.). 54: 2185-97. PMID 21826694 DOI: 10.1002/Hep.24599  0.491
2011 Szabo G, Zakhari S. Mechanisms of alcohol-mediated hepatotoxicity in human-immunodeficiency-virus-infected patients. World Journal of Gastroenterology. 17: 2500-6. PMID 21633654 DOI: 10.3748/Wjg.V17.I20.2500  0.423
2011 Dienstag JL, Ghany MG, Morgan TR, Di Bisceglie AM, Bonkovsky HL, Kim HY, Seeff LB, Szabo G, Wright EC, Sterling RK, Everson GT, Lindsay KL, Lee WM, Lok AS, Morishima C, et al. A prospective study of the rate of progression in compensated, histologically advanced chronic hepatitis C. Hepatology (Baltimore, Md.). 54: 396-405. PMID 21520194 DOI: 10.1002/Hep.24370  0.342
2011 Nath B, Levin I, Csak T, Petrasek J, Mueller C, Kodys K, Catalano D, Mandrekar P, Szabo G. Hepatocyte-specific hypoxia-inducible factor-1α is a determinant of lipid accumulation and liver injury in alcohol-induced steatosis in mice. Hepatology (Baltimore, Md.). 53: 1526-37. PMID 21520168 DOI: 10.1002/Hep.24256  0.43
2011 Csak T, Ganz M, Pespisa J, Kodys K, Dolganiuc A, Szabo G. Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells. Hepatology (Baltimore, Md.). 54: 133-44. PMID 21488066 DOI: 10.1002/Hep.24341  0.372
2011 Csak T, Dolganiuc A, Kodys K, Nath B, Petrasek J, Bala S, Lippai D, Szabo G. Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice. Hepatology (Baltimore, Md.). 53: 1917-31. PMID 21425308 DOI: 10.1002/Hep.24301  0.385
2011 Dolganiuc A, Szabo G. Dendritic cells in hepatitis C infection: can they (help) win the battle? Journal of Gastroenterology. 46: 432-47. PMID 21327958 DOI: 10.1007/S00535-011-0377-Y  0.323
2011 Szabo G, Mandrekar P, Petrasek J, Catalano D. The unfolding web of innate immune dysregulation in alcoholic liver injury. Alcoholism, Clinical and Experimental Research. 35: 782-6. PMID 21284666 DOI: 10.1111/J.1530-0277.2010.01398.X  0.529
2011 Petrasek J, Dolganiuc A, Csak T, Nath B, Hritz I, Kodys K, Catalano D, Kurt-Jones E, Mandrekar P, Szabo G. Interferon regulatory factor 3 and type I interferons are protective in alcoholic liver injury in mice by way of crosstalk of parenchymal and myeloid cells. Hepatology (Baltimore, Md.). 53: 649-60. PMID 21274885 DOI: 10.1002/Hep.24059  0.484
2011 Gao B, Seki E, Brenner DA, Friedman S, Cohen JI, Nagy L, Szabo G, Zakhari S. Innate immunity in alcoholic liver disease. American Journal of Physiology. Gastrointestinal and Liver Physiology. 300: G516-25. PMID 21252049 DOI: 10.1152/Ajpgi.00537.2010  0.512
2011 Csak T, Velayudham A, Hritz I, Petrasek J, Levin I, Lippai D, Catalano D, Mandrekar P, Dolganiuc A, Kurt-Jones E, Szabo G. Deficiency in myeloid differentiation factor-2 and toll-like receptor 4 expression attenuates nonalcoholic steatohepatitis and fibrosis in mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 300: G433-41. PMID 21233280 DOI: 10.1152/Ajpgi.00163.2009  0.404
2011 Bala S, Marcos M, Kodys K, Csak T, Catalano D, Mandrekar P, Szabo G. Up-regulation of microRNA-155 in macrophages contributes to increased tumor necrosis factor {alpha} (TNF{alpha}) production via increased mRNA half-life in alcoholic liver disease. The Journal of Biological Chemistry. 286: 1436-44. PMID 21062749 DOI: 10.1074/Jbc.M110.145870  0.356
2011 Petrasek J, Dolganiuc A, Csak T, Kurt-Jones EA, Szabo G. Type I interferons protect from Toll-like receptor 9-associated liver injury and regulate IL-1 receptor antagonist in mice. Gastroenterology. 140: 697-708.e4. PMID 20727895 DOI: 10.1053/J.Gastro.2010.08.020  0.426
2011 Cortez-Pinto H, Stickel F, Szabo G, Friedman S. S08Esbra-Niaaa Joint Symposium Alcoholic Liver Disease: From Pathogenesis To Treatments08.1Increasing Burden Of Alcoholic Liver Disease 2011 Alcohol and Alcoholism. 46. DOI: 10.1093/Alcalc/Agr115  0.505
2011 Bukong TN, Lo TC, Szabo G, Dolganiuc A. Alcohol Modulates the Transcriptome Leading to Cell Death and Immaturity of Human Embryonic Stem Cells-Derived Hepatocytes Gastroenterology. 140: S-906. DOI: 10.1016/S0016-5085(11)63760-8  0.341
2011 Bala S, Petrasek J, Ward J, Alao H, Levin I, Szabo G. Serum MicroRNA-122 and miR-155 as Biomarkers of Liver Injury and Inflammation in Models of Acute and Chronic Liver Disease Gastroenterology. 140: S-906. DOI: 10.1016/S0016-5085(11)63758-X  0.352
2011 Petrasek J, Dolganiuc A, Kodys K, Kurt-Jones EA, Szabo G. IL-1 Receptor Antagonist Treatment Attenuates Liver Steatosis and Inflammation in Alcoholic Liver Disease: The Role of Inflammasome Activation and IL-1β-Mediated Hepatocyte Steatosis and Cytotoxicity Gastroenterology. 140: S-887. DOI: 10.1016/S0016-5085(11)63688-3  0.443
2010 Szabo G, Mandrekar P. Focus on: Alcohol and the liver. Alcohol Research & Health : the Journal of the National Institute On Alcohol Abuse and Alcoholism. 33: 87-96. PMID 23579939  0.35
2010 Szabo G, Billiar TR, Machida K, Crispe IN, Seki E. Toll-like receptor signaling in liver diseases. Gastroenterology Research and Practice. 2010: 971270. PMID 21789039 DOI: 10.1155/2010/971270  0.488
2010 Szabo G, Bala S, Petrasek J, Gattu A. Gut-liver axis and sensing microbes. Digestive Diseases (Basel, Switzerland). 28: 737-44. PMID 21525758 DOI: 10.1159/000324281  0.499
2010 Nath B, Li Y, Carroll JE, Szabo G, Tseng JF, Shah SA. Alcohol exposure as a risk factor for adverse outcomes in elective surgery. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. 14: 1732-41. PMID 20839071 DOI: 10.1007/S11605-010-1350-4  0.354
2010 Petrasek J, Mandrekar P, Szabo G. Toll-like receptors in the pathogenesis of alcoholic liver disease. Gastroenterology Research and Practice. 2010. PMID 20827314 DOI: 10.1155/2010/710381  0.511
2010 Szabo G, Wands JR, Eken A, Osna NA, Weinman SA, Machida K, Joe Wang H. Alcohol and hepatitis C virus--interactions in immune dysfunctions and liver damage. Alcoholism, Clinical and Experimental Research. 34: 1675-86. PMID 20608905 DOI: 10.1111/J.1530-0277.2010.01255.X  0.483
2010 Szabo G. The 40th anniversary of the National Institute on Alcoholism and Alcohol Abuse: the impact on liver disease. Hepatology (Baltimore, Md.). 52: 10-2. PMID 20578124 DOI: 10.1002/Hep.23790  0.429
2010 Szabo G, Bala S. Alcoholic liver disease and the gut-liver axis. World Journal of Gastroenterology. 16: 1321-9. PMID 20238398 DOI: 10.3748/Wjg.V16.I11.1321  0.509
2010 Fontana RJ, Sanyal AJ, Ghany MG, Lee WM, Reid AE, Naishadham D, Everson GT, Kahn JA, Di Bisceglie AM, Szabo G, Morgan TR, Everhart JE. Factors that determine the development and progression of gastroesophageal varices in patients with chronic hepatitis C. Gastroenterology. 138: 2321-31, 2331.e1-2. PMID 20211180 DOI: 10.1053/J.Gastro.2010.02.058  0.311
2010 Chang S, Kodys K, Szabo G. Impaired expression and function of toll-like receptor 7 in hepatitis C virus infection in human hepatoma cells. Hepatology (Baltimore, Md.). 51: 35-42. PMID 19821521 DOI: 10.1002/Hep.23256  0.356
2010 Szabo G, Csak T, Ganz M, Dolganiuc A, Nath B, Petrasek J, Kodys K. 800 FATTY ACIDS INDUCE INFLAMMASOME ACTIVATION AND SENSITIZE TO LPS-INDUCED INTERLEUKIN-1β (IL-1β) SECRETION IN HEPATOCYTES IN NASH Journal of Hepatology. 52: S311. DOI: 10.1016/S0168-8278(10)60802-1  0.305
2010 Nath B, Li Y, Carroll J, Szabo G, Tseng JF, Shah SA. 791 Alcohol Consumption as a Modifiable Risk Factor in Elective Surgery Gastroenterology. 138. DOI: 10.1016/S0016-5085(10)63960-1  0.331
2010 Petrasek J, Dolganiuc A, Kurt-Jones EA, Szabo G. 238 Type I Interferons Regulate IL-1 Receptor Antagonist and Protect From TollLike Receptor 9-Mediated Liver Injury in Mice Gastroenterology. 138: S-781. DOI: 10.1016/S0016-5085(10)63598-6  0.359
2010 Nath B, Levin I, Szabo G. 71 Hepatocyte-Specific Hypoxia-Inducible Factor 1α Mediates TNFα Secretion and Liver Injury in a Mouse Model of Alcoholic Steatohepatitis Gastroenterology. 138: S-774. DOI: 10.1016/S0016-5085(10)63568-8  0.443
2009 Bala S, Marcos M, Szabo G. Emerging role of microRNAs in liver diseases. World Journal of Gastroenterology. 15: 5633-40. PMID 19960558 DOI: 10.3748/Wjg.15.5633  0.375
2009 Dolganiuc A, Petrasek J, Kodys K, Catalano D, Mandrekar P, Velayudham A, Szabo G. MicroRNA expression profile in Lieber-DeCarli diet-induced alcoholic and methionine choline deficient diet-induced nonalcoholic steatohepatitis models in mice. Alcoholism, Clinical and Experimental Research. 33: 1704-10. PMID 19572984 DOI: 10.1111/J.1530-0277.2009.01007.X  0.352
2009 Mandrekar P, Bala S, Catalano D, Kodys K, Szabo G. The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytes. Journal of Immunology (Baltimore, Md. : 1950). 183: 1320-7. PMID 19561104 DOI: 10.4049/Jimmunol.0803206  0.444
2009 Mandrekar P, Szabo G. Signalling pathways in alcohol-induced liver inflammation. Journal of Hepatology. 50: 1258-66. PMID 19398236 DOI: 10.1016/J.Jhep.2009.03.007  0.52
2009 Nath B, Szabo G. Alcohol-induced modulation of signaling pathways in liver parenchymal and nonparenchymal cells: implications for immunity. Seminars in Liver Disease. 29: 166-77. PMID 19387916 DOI: 10.1055/S-0029-1214372  0.492
2009 Dolganiuc A, Szabo G. In vitro and in vivo models of acute alcohol exposure. World Journal of Gastroenterology. 15: 1168-77. PMID 19291816 DOI: 10.3748/Wjg.15.1168  0.387
2009 Velayudham A, Dolganiuc A, Ellis M, Petrasek J, Kodys K, Mandrekar P, Szabo G. VSL#3 probiotic treatment attenuates fibrosis without changes in steatohepatitis in a diet-induced nonalcoholic steatohepatitis model in mice. Hepatology (Baltimore, Md.). 49: 989-97. PMID 19115316 DOI: 10.1002/Hep.22711  0.401
2009 Lau AH, Szabo G, Thomson AW. Antigen-presenting cells under the influence of alcohol. Trends in Immunology. 30: 13-22. PMID 19059005 DOI: 10.1016/J.It.2008.09.005  0.439
2009 Csak T, Dolganiuc A, Nath B, Patrasek J, Kodys K, Szabo G. Non-alcoholic steatohepatitis sensitizes to TLR9-induced liver injury Zeitschrift FüR Gastroenterologie. 47. DOI: 10.1055/S-0029-1223987  0.467
2009 Petrasek J, Dolganiuc A, Kurt-Jones EA, Szabo G. 537 Type I Interferon Induction and Signaling Protect from Liver Injury and Granulomas Through Regulation of IL-1 Receptor Antagonist and Dendritic Cell Recruitment in Mice Gastroenterology. 136: A-802-A-803. DOI: 10.1016/S0016-5085(09)63703-3  0.378
2009 Bala S, Tang A, Szabo G. Bcl-3 Attenuates LPS-induced macrophage TNFα production through interaction with NF-κB p50 homodimers after acute alcohol exposure Cytokine. 48: 124. DOI: 10.1016/J.Cyto.2009.07.523  0.391
2009 Mandrekar P, Bala S, Catalano D, Kodys K, Szabo G. IRAK-M is a central regulator of the opposite effects of acute and chronic alcohol exposure on LPS-induced inflammation in human monocytes Cytokine. 48: 106. DOI: 10.1016/J.Cyto.2009.07.446  0.398
2009 Mandrekar P, Bala S, Catalano D, Kodys K, Szabo G. IRAK-M plays a central role in differential regulation of acute and chronic alcohol exposure on LPS-induced inflammation in human monocytes Alcohol. 43: 669. DOI: 10.1016/J.Alcohol.2009.09.015  0.444
2009 Bala S, Tang A, Szabo G. Acute alcohol treatment attenuates LPS-induced macrophage TNFα production through Bcl3 induction and Bcl3-NF-κB p50 interaction Alcohol. 43: 666. DOI: 10.1016/J.Alcohol.2009.09.004  0.397
2008 Szabo G, Mandrekar P. A recent perspective on alcohol, immunity, and host defense. Alcoholism, Clinical and Experimental Research. 33: 220-32. PMID 19053973 DOI: 10.1111/J.1530-0277.2008.00842.X  0.397
2008 Dolganiuc A, Paek E, Kodys K, Thomas J, Szabo G. Myeloid dendritic cells of patients with chronic HCV infection induce proliferation of regulatory T lymphocytes. Gastroenterology. 135: 2119-27. PMID 18835391 DOI: 10.1053/J.Gastro.2008.07.082  0.305
2008 Hritz I, Velayudham A, Dolganiuc A, Kodys K, Mandrekar P, Kurt-Jones E, Szabo G. Bone marrow-derived immune cells mediate sensitization to liver injury in a myeloid differentiation factor 88-dependent fashion. Hepatology (Baltimore, Md.). 48: 1342-7. PMID 18798338 DOI: 10.1002/Hep.22557  0.437
2008 Hritz I, Mandrekar P, Velayudham A, Catalano D, Dolganiuc A, Kodys K, Kurt-Jones E, Szabo G. The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88. Hepatology (Baltimore, Md.). 48: 1224-31. PMID 18792393 DOI: 10.1002/Hep.22470  0.519
2008 Szabo G, Dolganiuc A. Hepatitis C and innate immunity: recent advances. Clinics in Liver Disease. 12: 675-92, x. PMID 18625434 DOI: 10.1016/J.Cld.2008.03.003  0.347
2008 Norkina O, Dolganiuc A, Catalano D, Kodys K, Mandrekar P, Syed A, Efros M, Szabo G. Acute alcohol intake induces SOCS1 and SOCS3 and inhibits cytokine-induced STAT1 and STAT3 signaling in human monocytes. Alcoholism, Clinical and Experimental Research. 32: 1565-73. PMID 18616672 DOI: 10.1111/J.1530-0277.2008.00726.X  0.406
2008 Dolganiuc A, Szabo G. T cells with regulatory activity in hepatitis C virus infection: what we know and what we don't. Journal of Leukocyte Biology. 84: 614-22. PMID 18495782 DOI: 10.1189/Jlb.1107770  0.332
2008 Szabo G, Mandrekar P. Human monocytes, macrophages, and dendritic cells: alcohol treatment methods. Methods of Molecular Biology. 447: 113-124. PMID 18369915 DOI: 10.1007/978-1-59745-242-7_9  0.437
2008 Szabo G, Dolganiuc A. The role of plasmacytoid dendritic cell-derived IFN alpha in antiviral immunity. Critical Reviews in Immunology. 28: 61-94. PMID 18298384 DOI: 10.1615/Critrevimmunol.V28.I1.40  0.321
2008 Seeff LB, Curto TM, Szabo G, Everson GT, Bonkovsky HL, Dienstag JL, Shiffman ML, Lindsay KL, Lok AS, Di Bisceglie AM, Lee WM, Ghany MG. Herbal product use by persons enrolled in the hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial. Hepatology (Baltimore, Md.). 47: 605-12. PMID 18157835 DOI: 10.1002/Hep.22044  0.334
2008 Szabo G, Mandrekar P, Dolganiuc A. Innate immune response and hepatic inflammation. Seminars in Liver Disease. 27: 339-50. PMID 17979071 DOI: 10.1055/S-2007-991511  0.458
2008 Velayudham A, Hritz I, Catalano D, Mandrekar P, Szabo G. 107 Liver Fibrosis in Diet-Induced Steatohepatitis Is Attenuated By Deficiency in the Expression of Toll-Like Receptor 4 (TLR4), or the TLR Adapter, MyD88 Gastroenterology. 134: A-753-A-754. DOI: 10.1016/S0016-5085(08)63519-2  0.395
2008 Chang S, Szabo G. 1 HCV Targets TLR7 Receptor Expression By Reducing TLR7 mRNA Stability in HCV Replicating Cells Gastroenterology. 134: A-750. DOI: 10.1016/S0016-5085(08)63501-5  0.318
2008 Bagshahi H, Czerniach DR, Kelly JJ, Litwin DEM, Szabo G, Perugini RA. QS95. Insulin Resistance Is A Predictor for Presence of and Grade of Inflammation in Non-Alcoholic Fatty Liver Disease Journal of Surgical Research. 144: 305. DOI: 10.1016/J.Jss.2007.12.335  0.401
2007 Szabo G, Dolganiuc A. Hepatitis C core protein - the "core" of immune deception? Journal of Hepatology. 48: 8-11. PMID 18023495 DOI: 10.1016/J.Jhep.2007.10.005  0.316
2007 Dolganiuc A, Norkina O, Kodys K, Catalano D, Bakis G, Marshall C, Mandrekar P, Szabo G. Viral and host factors induce macrophage activation and loss of toll-like receptor tolerance in chronic HCV infection. Gastroenterology. 133: 1627-36. PMID 17916356 DOI: 10.1053/J.Gastro.2007.08.003  0.396
2007 Szabo G, Chang S, Dolganiuc A. Altered innate immunity in chronic hepatitis C infection: cause or effect? Hepatology (Baltimore, Md.). 46: 1279-90. PMID 17886338 DOI: 10.1002/Hep.21938  0.348
2007 Chang S, Dolganiuc A, Szabo G. Toll-like receptors 1 and 6 are involved in TLR2-mediated macrophage activation by hepatitis C virus core and NS3 proteins. Journal of Leukocyte Biology. 82: 479-87. PMID 17595379 DOI: 10.1189/Jlb.0207128  0.402
2007 Szabo G, Mandrekar P, Oak S, Mayerle J. Effect of ethanol on inflammatory responses. Implications for pancreatitis. Pancreatology : Official Journal of the International Association of Pancreatology (Iap) ... [Et Al.]. 7: 115-23. PMID 17592223 DOI: 10.1159/000104236  0.413
2007 Norkina O, Dolganiuc A, Shapiro T, Kodys K, Mandrekar P, Szabo G. Acute alcohol activates STAT3, AP-1, and Sp-1 transcription factors via the family of Src kinases to promote IL-10 production in human monocytes. Journal of Leukocyte Biology. 82: 752-62. PMID 17575268 DOI: 10.1189/Jlb.0207099  0.423
2007 Mandrekar P, Jeliazkova V, Catalano D, Szabo G. Acute alcohol exposure exerts anti-inflammatory effects by inhibiting IκB kinase activity and p65 phosphorylation in human monocytes Journal of Immunology. 178: 7686-7693. PMID 17548605 DOI: 10.4049/Jimmunol.178.12.7686  0.429
2007 Davis GL, Krawczynski K, Szabo G. Hepatitis C virus infection--pathobiology and implications for new therapeutic options. Digestive Diseases and Sciences. 52: 857-75. PMID 17333350 DOI: 10.1007/S10620-006-9484-7  0.36
2007 Szabo G, Dolganiuc A, Dai Q, Pruett SB. TLR4, ethanol, and lipid rafts: a new mechanism of ethanol action with implications for other receptor-mediated effects. Journal of Immunology (Baltimore, Md. : 1950). 178: 1243-9. PMID 17237368 DOI: 10.4049/Jimmunol.178.3.1243  0.332
2007 Szabo G, Dolganiuc A. HCV immunopathogenesis: virus-induced strategies against host immunity. Clinics in Liver Disease. 10: 753-71. PMID 17164116 DOI: 10.1016/J.Cld.2006.08.028  0.313
2007 Velayudham A, Hritz I, Dolganiuc A, Mandrekar P, Kurt-Jones E, Szabo G. MyD88-Dependent Bone Marrow-Derived Cells Mediate Sensitization to Lipopolysaccharide-Induced Acute Liver Injury American Journal of Gastroenterology. 102: S237. DOI: 10.14309/00000434-200709002-00333  0.334
2007 Szabo G, Dolganiuc A, Chang S, Kodys K. [466] TLR-MEDIATED SUBVERSION OF INNATE IMMUNITY IN CHRONIC HCV INFECTION: AUGMENTATION OF MONOCYTE TNFa LEADS TO DECREASED IFN-o PRODUCTION BY PLASMACYTOID DENDRITIC CELLS Journal of Hepatology. 46: S177. DOI: 10.1016/S0168-8278(07)62064-9  0.35
2007 Szabo G. Moderate Drinking, Inflammation, and Liver Disease Annals of Epidemiology. 17. DOI: 10.1016/J.Annepidem.2007.01.012  0.506
2006 Dolganiuc A, Chang SS, Kodys K, Mandrekar P, Bakis G, Cormier M, Szabo G. Hepatitis C Virus (HCV) Core Protein-Induced, Monocyte-Mediated Mechanisms of Reduced IFN-α and Plasmacytoid Dendritic Cell Loss in Chronic HCV Infection Journal of Immunology. 177: 6758-6768. PMID 17082589 DOI: 10.4049/Jimmunol.177.10.6758  0.346
2006 Velayudham A, Hritz I, Dolganiuc A, Mandrekar P, Kurt-Jones E, Szabo G. Critical role of toll-like receptors and the common TLR adaptor, MyD88, in induction of granulomas and liver injury. Journal of Hepatology. 45: 813-24. PMID 16935388 DOI: 10.1016/J.Jhep.2006.06.017  0.401
2006 Brown LA, Cook RT, Jerrells TR, Kolls JK, Nagy LE, Szabo G, Wands JR, Kovacs EJ. Acute and chronic alcohol abuse modulate immunity. Alcoholism, Clinical and Experimental Research. 30: 1624-31. PMID 16930226 DOI: 10.1111/J.1530-0277.2006.00195.X  0.454
2006 Drechsler Y, Dolganiuc A, Norkina O, Romics L, Li W, Kodys K, Bach FH, Mandrekar P, Szabo G. Heme oxygenase-1 mediates the anti-inflammatory effects of acute alcohol on IL-10 induction involving p38 MAPK activation in monocytes. Journal of Immunology (Baltimore, Md. : 1950). 177: 2592-600. PMID 16888021 DOI: 10.4049/Jimmunol.177.4.2592  0.661
2006 Szabo G, Dolganiuc A, Mandrekar P. Pattern recognition receptors: a contemporary view on liver diseases. Hepatology (Baltimore, Md.). 44: 287-98. PMID 16871558 DOI: 10.1002/Hep.21308  0.401
2006 Romics L, Szabo G, Coffey JC, Wang JH, Redmond HP. The emerging role of toll-like receptor pathways in surgical diseases. Archives of Surgery (Chicago, Ill. : 1960). 141: 595-601. PMID 16785361 DOI: 10.1001/Archsurg.141.6.595  0.581
2006 Oak S, Mandrekar P, Catalano D, Kodys K, Szabo G. TLR2- and TLR4-mediated signals determine attenuation or augmentation of inflammation by acute alcohol in monocytes. Journal of Immunology (Baltimore, Md. : 1950). 176: 7628-35. PMID 16751410 DOI: 10.4049/Jimmunol.176.12.7628  0.465
2006 Spies C, Eggers V, Szabo G, Lau A, von Dossow V, Schoenfeld H, Althoff H, Hegenscheid K, Bohm B, Schroeder T, Pfeiffer S, Ziemer S, Paschen C, Klein M, Marks C, et al. Intervention at the level of the neuroendocrine-immune axis and postoperative pneumonia rate in long-term alcoholics. American Journal of Respiratory and Critical Care Medicine. 174: 408-14. PMID 16728716 DOI: 10.1164/Rccm.200506-907Oc  0.363
2006 Crews FT, Bechara R, Brown LA, Guidot DM, Mandrekar P, Oak S, Qin L, Szabo G, Wheeler M, Zou J. Cytokines and alcohol. Alcoholism, Clinical and Experimental Research. 30: 720-30. PMID 16573591 DOI: 10.1111/J.1530-0277.2006.00084.X  0.467
2006 Szabo G, Aloman C, Polyak SJ, Weinman SA, Wands J, Zakhari S. Hepatitis C infection and alcohol use: A dangerous mix for the liver and antiviral immunity. Alcoholism, Clinical and Experimental Research. 30: 709-19. PMID 16573590 DOI: 10.1111/J.1530-0277.2006.00083.X  0.485
2006 Dolganiuc A, Garcia C, Kodys K, Szabo G. Distinct Toll-like receptor expression in monocytes and T cells in chronic HCV infection. World Journal of Gastroenterology. 12: 1198-204. PMID 16534871 DOI: 10.3748/Wjg.V12.I8.1198  0.351
2006 Mandrekar P, Catalano D, White B, Szabo G. Moderate alcohol intake in humans attenuates monocyte inflammatory responses: inhibition of nuclear regulatory factor kappa B and induction of interleukin 10. Alcoholism, Clinical and Experimental Research. 30: 135-9. PMID 16433741 DOI: 10.1111/J.1530-0277.2006.00012.X  0.461
2006 Dolganiuc A, Bakis G, Kodys K, Mandrekar P, Szabo G. Acute ethanol treatment modulates Toll-like receptor-4 association with lipid rafts. Alcoholism, Clinical and Experimental Research. 30: 76-85. PMID 16433734 DOI: 10.1111/J.1530-0277.2006.00003.X  0.423
2005 Szabo G, Velayudham A, Romics L, Mandrekar P. Modulation of non-alcoholic steatohepatitis by pattern recognition receptors in mice: the role of toll-like receptors 2 and 4. Alcoholism, Clinical and Experimental Research. 29: 140S-145S. PMID 16344599 DOI: 10.1097/01.Alc.0000189287.83544.33  0.673
2005 Szabo G, Weinman SA, Gao B, Polyak SJ, Mandrekar P, Thiele GM. RSA 2004: combined basic research satellite symposium - session four: hepatitis virus and alcohol interactions in immunity and liver disease. Alcoholism, Clinical and Experimental Research. 29: 1753-7. PMID 16205377 DOI: 10.1097/01.Alc.0000179319.44684.58  0.489
2005 Mandrekar P, Pruett S, Arteel G, Thiele GM, Szabo G. RSA 2004: Combined Basic Research Satellite Symposium – Session Two: Toll‐Like Receptors and Organ Damage Alcoholism: Clinical and Experimental Research. 29: 1744-1748. PMID 16205375 DOI: 10.1097/01.Alc.0000179315.09591.55  0.465
2005 Romics L, Dolganiuc A, Velayudham A, Kodys K, Mandrekar P, Golenbock D, Kurt-Jones E, Szabo G. Toll-like receptor 2 mediates inflammatory cytokine induction but not sensitization for liver injury by Propioni- bacterium acnes. Journal of Leukocyte Biology. 78: 1255-64. PMID 16204620 DOI: 10.1189/Jlb.0804448  0.648
2005 Szabo G, Dolganiuc A. Subversion of plasmacytoid and myeloid dendritic cell functions in chronic HCV infection. Immunobiology. 210: 237-47. PMID 16164031 DOI: 10.1016/J.Imbio.2005.05.018  0.346
2005 Romics L, Mandrekar P, Kodys K, Velayudham A, Drechsler Y, Dolganiuc A, Szabo G. Increased lipopolysaccharide sensitivity in alcoholic fatty livers is independent of leptin deficiency and toll-like receptor 4 (TLR4) or TLR2 mRNA expression. Alcoholism, Clinical and Experimental Research. 29: 1018-26. PMID 15976528 DOI: 10.1097/01.Alc.0000167744.60838.4A  0.687
2005 Szabo G, Dolganiuc A, Mandrekar P, White B. Inhibition of antigen-presenting cell functions by alcohol: implications for hepatitis C virus infection. Alcohol (Fayetteville, N.Y.). 33: 241-9. PMID 15596093 DOI: 10.1016/J.Alcohol.2004.07.003  0.436
2004 Romics L, Coffey JC, Wang JH, Redmond HP, Szabó G. [Significance of Toll-like receptors in the pathophysiology of surgical sepsis]. Magyar SebéSzet. 57: 229-35. PMID 15570917  0.566
2004 Dolganiuc A, Oak S, Kodys K, Golenbock DT, Finberg RW, Kurt-Jones E, Szabo G. Hepatitis C core and nonstructural 3 proteins trigger toll-like receptor 2-mediated pathways and inflammatory activation. Gastroenterology. 127: 1513-24. PMID 15521019 DOI: 10.1053/J.Gastro.2004.08.067  0.394
2004 Romics L, Kodys K, Dolganiuc A, Graham L, Velayudham A, Mandrekar P, Szabo G. Diverse regulation of NF-kappaB and peroxisome proliferator-activated receptors in murine nonalcoholic fatty liver. Hepatology (Baltimore, Md.). 40: 376-85. PMID 15368442 DOI: 10.1002/Hep.20304  0.681
2004 Romics L, Dolganiuc A, Kodys K, Drechsler Y, Oak S, Velayudham A, Mandrekar P, Szabo G. Selective priming to Toll-like receptor 4 (TLR4), not TLR2, ligands by P. acnes involves up-regulation of MD-2 in mice. Hepatology (Baltimore, Md.). 40: 555-64. PMID 15349893 DOI: 10.1002/Hep.20350  0.631
2004 Mandrekar P, Catalano D, Dolganiuc A, Kodys K, Szabo G. Inhibition of myeloid dendritic cell accessory cell function and induction of T cell anergy by alcohol correlates with decreased IL-12 production. Journal of Immunology (Baltimore, Md. : 1950). 173: 3398-407. PMID 15322204 DOI: 10.4049/Jimmunol.173.5.3398  0.407
2004 Szabo G, Catalano D, White B, Mandrekar P. Acute alcohol consumption inhibits accessory cell function of monocytes and dendritic cells. Alcoholism, Clinical and Experimental Research. 28: 824-8. PMID 15166660 DOI: 10.1097/01.Alc.0000127104.80398.9B  0.433
2004 Velayudham A, Ellis M, Szabo G. VSL#3 TREATMENT RESULTS IN INCREASED LIVER DAMAGE, NFκB, AP-1 ACTIVATION AND REDUCED LEVELS OF HEPATOPROTECTIVE CYTOKINES IN DIET-INDUCED NASH: 292 The American Journal of Gastroenterology. 99. DOI: 10.14309/00000434-200410001-00289  0.362
2004 Romics L, Velayudham A, Dolganiuc A, Szabo G. Upregulation of toll-like receptor 4 (TLR4)/MD-2 complex in LPS hypersensitive livers in mice Zeitschrift FüR Gastroenterologie. 42. DOI: 10.1055/S-2004-827023  0.593
2003 Dolganiuc A, Kodys K, Kopasz A, Marshall C, Mandrekar P, Szabo G. Additive inhibition of dendritic cell allostimulatory capacity by alcohol and hepatitis C is not restored by DC maturation and involves abnormal IL-10 and IL-2 induction. Alcoholism, Clinical and Experimental Research. 27: 1023-31. PMID 12824825 DOI: 10.1097/01.Alc.0000071745.63433.32  0.447
2003 Dolganiuc A, Kodys K, Kopasz A, Marshall C, Do T, Romics L, Mandrekar P, Zapp M, Szabo G. Hepatitis C virus core and nonstructural protein 3 proteins induce pro- and anti-inflammatory cytokines and inhibit dendritic cell differentiation. Journal of Immunology (Baltimore, Md. : 1950). 170: 5615-24. PMID 12759441 DOI: 10.4049/Jimmunol.170.11.5615  0.602
2003 Romics L, Frendl G, Szabó G. [Cellular and molecular changes of the liver in sepsis and in systemic inflammatory response syndrome (SIRS)]. Orvosi Hetilap. 144: 499-506. PMID 12731336  0.599
2003 Szabo G. Pathogenic interactions between alcohol and hepatitis C. Current Gastroenterology Reports. 5: 86-92. PMID 12530953 DOI: 10.1007/S11894-003-0014-X  0.462
2003 Mandrekar P, Bellerose G, Szabo G. Inhibition of NF-kappa B binding correlates with increased nuclear glucocorticoid receptor levels in acute alcohol-treated human monocytes. Alcoholism, Clinical and Experimental Research. 26: 1872-9. PMID 12500112 DOI: 10.1097/01.Alc.0000042220.48841.9E  0.41
2003 MANDREKAR P, BELLEROSE G, CATALANO D, SZABO G. 930 Diverse regulation of NFKAPPAB activation and TNF-alpha production after acute and chronic alcohol treatment in human monocytes Hepatology. 38: 605-605. DOI: 10.1016/S0270-9139(03)80968-0  0.383
2003 DOLGANIUC A, KODYS K, KOPASZ A, OAK S, MANDREKAR P, KURTJONES E, GOLENBOCK D, SZABO G. 610 Pattern recognition of HCV core and NS3 proteins by innate immune cells: Role for TLR2 but not for TLR4 Hepatology. 38: 456-456. DOI: 10.1016/S0270-9139(03)80652-3  0.332
2003 SZABO G, ROMICSJR L, KODYS K, DOLGANIUC A, MANDREKAR P, GOLENBOCK D. 197 Distinct roles for toll-like receptor 2(TLR2) and TLR4 in liver sensitization and injury Hepatology. 38: 250-251. DOI: 10.1016/S0270-9139(03)80240-9  0.388
2003 Romics L, Kodys K, Li W, Dolganiuc A, Szabo G. Propionibacterium acnes sensitizes the liver for toll-like receptor 4, not for Tlr2 mediated injury involving up-regulation of the Tlr4/Md-2 receptor complex Gastroenterology. 124: A720. DOI: 10.1016/S0016-5085(03)83636-3  0.624
2003 Romics L, Kodys K, Golenbock D, Szabo G. Propionibacterium acnes triggers inflammatory responses via toll-like receptor 2 and sensitizes for liver injury via Tlr2-independent pathways Gastroenterology. 124: A720. DOI: 10.1016/S0016-5085(03)83635-1  0.638
2003 Dolganiuc A, Kodys K, Kurt-Jones E, Golenbock D, Szabo G. Hepatitis C virus core and NS3, not E2, proteins activate inflammatory pathways via the pattern recognition receptor, toll-like receptor 2 Gastroenterology. 124: A715. DOI: 10.1016/S0016-5085(03)83609-0  0.335
2002 Szabo G, Romics L, Frendl G. Liver in sepsis and systemic inflammatory response syndrome. Clinics in Liver Disease. 6: 1045-66, x. PMID 12516206 DOI: 10.1016/S1089-3261(02)00058-2  0.626
2002 Thiele GM, Szabo G, Kovacs EJ, Bautista AP, Sosa L, Jerrells TR. Modulation of immunity and viral-host interactions by alcohol. Alcoholism, Clinical and Experimental Research. 26: 1897-908. PMID 12500115 DOI: 10.1111/J.1530-0277.2002.Tb02498.X  0.443
2002 Mandrekar P, Dolganiuc A, Bellerose G, Kodys K, Romics L, Nizamani R, Szabo G. Acute alcohol inhibits the induction of nuclear regulatory factor kappa B activation through CD14/toll-like receptor 4, interleukin-1, and tumor necrosis factor receptors: a common mechanism independent of inhibitory kappa B alpha degradation? Alcoholism, Clinical and Experimental Research. 26: 1609-14. PMID 12436048 DOI: 10.1111/J.1530-0277.2002.Tb02462.X  0.648
2002 Bonkovsky HL, Azar R, Bird S, Szabo G, Banner B. Severe cholestatic hepatitis caused by thiazolidinediones: risks associated with substituting rosiglitazone for troglitazone. Digestive Diseases and Sciences. 47: 1632-7. PMID 12141828 DOI: 10.1023/A:1015895925374  0.336
2002 Szabo G, Mandrekar P. Ethanol-mediated regulation of transcription factors in immunocompetent cells. Frontiers in Bioscience : a Journal and Virtual Library. 7: a80-9. PMID 11991856 DOI: 10.2741/A742  0.323
2002 Szabo G. Ethanol-mediated regulation of transcription factors in immunocompetent cells Frontiers in Bioscience. 7: a80. DOI: 10.2741/Szabo  0.433
2002 Drechsler Y, Chavan SS, Catalano D, Mandrekar P, Szabo G. FcγR cross-linking mediates NF-κB activation, reduced antigen presentation capacity, and decreased IL-12 production in monocytes without modulation of myeloid dendritic cell development Journal of Leukocyte Biology. 72: 657-667. DOI: 10.1189/Jlb.72.4.657  0.33
2001 Szabo G, Catalano D, Bellerose G, Mandrekar P. Interferon alpha and Alcohol Augment Nuclear Regulatory Factor-kappaB Activation in HepG2 Cells, and Interferon alpha Increases Pro-Inflammatory Cytokine Production Alcoholism: Clinical and Experimental Research. 25: 1188-1197. DOI: 10.1111/J.1530-0277.2001.Tb02335.X  0.471
2001 Szabo G, Mandrekar P, Dolganiuc A, Catalano D, Kodys K. Reduced Alloreactive T-Cell Activation After Alcohol Intake is Due to Impaired Monocyte Accessory Cell Function and Correlates With Elevated IL-10, IL-13, and Decreased IFNgamma Levels Alcoholism: Clinical and Experimental Research. 25: 1766-1772. DOI: 10.1111/J.1530-0277.2001.Tb02188.X  0.422
2001 Szabo G, Mandrekar P. Alcohol consumption impairs antigen-specific T cell activation: The rele of monocytes and dendritic cells Gastroenterology. 120: A554. DOI: 10.1016/S0016-5085(08)82753-9  0.369
2000 Szabo G, Katz E, Bonkovsky HL. Management of recurrent hepatitis C after liver transplantation: a concise review The American Journal of Gastroenterology. 95: 2164-2170. PMID 11007212 DOI: 10.1111/J.1572-0241.2000.02296.X  0.338
2000 Fang WC, Saltzman JR, Rososhansky S, Szabo G, Heard SO, Banner BF, Chari R, Katz E. Acceptance of an ABO-Incompatible Mismatched (AB+ to O+) Liver Allograft With the Use of Daclizumab and Mycophenolate Mofetil Liver Transplantation. 6: 497-500. PMID 10915175 DOI: 10.1053/Jlts.2000.6448  0.301
2000 Szabo G. New insights into the the molecular mechanisms of alcoholic hepatitis: a potential role for NF-kappaB activation? The Journal of Laboratory and Clinical Medicine. 135: 367-9. PMID 10811050 DOI: 10.1067/Mlc.2000.106452  0.434
2000 Szabo G. Consequences of alcohol consumption on host defence. Alcohol and Alcoholism (Oxford, Oxfordshire). 34: 830-41. PMID 10659718 DOI: 10.1093/Alcalc/34.6.830  0.435
1999 Mandrekar P, Catalano D, Szabo G. Inhibition of lipopolysaccharide-mediated NFκB activation by ethanol in human monocytes International Immunology. 11: 1781-1790. PMID 10545482 DOI: 10.1093/Intimm/11.11.1781  0.46
1999 Szabo G, Chavan S, Mandrekar P, Catalano D. Acute alcohol consumption attenuates interleukin-8 (IL-8) and monocyte chemoattractant peptide-1 (MCP-1) induction in response to ex vivo stimulation. Journal of Clinical Immunology. 19: 67-76. PMID 10080106 DOI: 10.1023/A:1020518703050  0.453
1999 Szabo G, Girouard L, Mandrekar P, Catalano D. Regulation of monocyte IL-12 production: augmentation by lymphocyte contact and acute ethanol treatment, inhibition by elevated intracellular cAMP. International Journal of Immunopharmacology. 20: 491-503. PMID 9818793 DOI: 10.1016/S0192-0561(98)00046-0  0.328
1998 Szabo G. Monocytes, Alcohol Use, and Altered Immunity Alcoholism: Clinical and Experimental Research. 22: 216S-219S. DOI: 10.1111/J.1530-0277.1998.Tb04005.X  0.443
1998 Girouard L, Mandrekar P, Catalano D, Szabo G. Regulation of Monocyte Interleukin-12 Production by Acute Alcohol: A Role for Inhibition by Interleukin-10 Alcoholism: Clinical and Experimental Research. 22: 211-216. DOI: 10.1111/J.1530-0277.1998.Tb03640.X  0.336
1998 Szabo G, Mandrekar P, Catalano D. Acute alcohol regulation of inflammatory cytokine production in human monocytes: A role for NF-B Gastroenterology. 114: A1350. DOI: 10.1016/S0016-5085(98)85479-6  0.409
1997 Mandrekar P, Catalano D, Girouard L, Szabo G. Human monocyte IL-10 production is increased by acute ethanol treatment. Cytokine. 8: 567-77. PMID 8891438 DOI: 10.1006/Cyto.1996.0076  0.316
1997 Szabo G, Mandrekar P, Girouard L, Catalano D. Regulation of human monocyte functions by acute ethanol treatment: decreased tumor necrosis factor-alpha, interleukin-1 beta and elevated interleukin-10, and transforming growth factor-beta production. Alcoholism, Clinical and Experimental Research. 20: 900-7. PMID 8865966 DOI: 10.1111/J.1530-0277.1996.Tb05269.X  0.356
1997 Mandrekar P, Catalano D, Szabo G. Alcohol-Induced Regulation of Nuclear Regulatory Factor-Kbeta in Human Monocytes Alcoholism: Clinical and Experimental Research. 21: 988-994. DOI: 10.1111/J.1530-0277.1997.Tb04242.X  0.35
1995 Szabo G, Mandrekar P, Catalano D. Inhibition of superantigen-induced T cell proliferation and monocyte IL-1β, TNF-α, and IL-6 production by acute ethanol treatment Journal of Leukocyte Biology. 58: 342-350. PMID 7665990 DOI: 10.1002/Jlb.58.3.342  0.355
1994 Szabo G, Mandrekar P, Verma B, Isaac A, Catalano D. Acute ethanol consumption synergizes with trauma to increase monocyte tumor necrosis factor alpha production late postinjury. Journal of Clinical Immunology. 14: 340-52. PMID 7883861 DOI: 10.1007/Bf01546318  0.371
1990 Miller-Graziano CL, Szabo G, Kodys K, Griffey K. Aberrations in post-trauma monocyte (MO) subpopulation: role in septic shock syndrome. Journal of Trauma-Injury Infection and Critical Care. 30: 86-96. DOI: 10.1097/00005373-199012001-00020  0.308
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