Year |
Citation |
Score |
2018 |
Smith JT, Roseweir A, Millar M, Clarke I, Millar RP. Stimulation of growth hormone by kisspeptin antagonists in ewes. The Journal of Endocrinology. PMID 29549187 DOI: 10.1530/Joe-18-0074 |
0.338 |
|
2017 |
Clarke IJ, Li Q, Henry BA, Millar RP. Continuous Kisspeptin restores Luteinizing Hormone pulsatility following cessation by a Neurokinin B antagonist in female sheep. Endocrinology. PMID 29126131 DOI: 10.1210/en.2017-00737 |
0.324 |
|
2016 |
Newton CL, Anderson RC, Millar RP. Therapeutic Neuroendocrine Agonist and Antagonist Analogs of Hypothalamic Neuropeptides as Modulators of the Hypothalamic-Pituitary-Gonadal Axis. Endocrine Development. 30: 106-29. PMID 26684214 DOI: 10.1159/000439337 |
0.337 |
|
2015 |
Fraser GL, Hoveyda HR, Clarke IJ, Ramaswamy S, Plant TM, Rose C, Millar RP. The NK3 Receptor Antagonist ESN364 Interrupts Pulsatile LH Secretion and Moderates Levels of Ovarian Hormones Throughout the Menstrual Cycle. Endocrinology. 156: 4214-25. PMID 26305889 DOI: 10.1210/En.2015-1409 |
0.3 |
|
2015 |
Zmora N, Stubblefield JD, Wong TT, Levavi-Sivan B, Millar RP, Zohar Y. Kisspeptin Antagonists Reveal Kisspeptin 1 and Kisspeptin 2 Differential Regulation of Reproduction in the Teleost, Morone saxatilis. Biology of Reproduction. 93: 76. PMID 26246220 DOI: 10.1095/Biolreprod.115.131870 |
0.361 |
|
2015 |
Millar RP, Babwah AV. KISS1R: Hallmarks of an Effective Regulator of the Neuroendocrine Axis. Neuroendocrinology. 101: 193-210. PMID 25765628 DOI: 10.1159/000381457 |
0.31 |
|
2015 |
Li Q, Millar RP, Clarke IJ, Smith JT. Evidence that Neurokinin B Controls Basal Gonadotropin-Releasing Hormone Secretion but Is Not Critical for Estrogen-Positive Feedback in Sheep. Neuroendocrinology. 101: 161-74. PMID 25677216 DOI: 10.1159/000377702 |
0.304 |
|
2013 |
Roseweir AK, Millar RP. Kisspeptin antagonists. Advances in Experimental Medicine and Biology. 784: 159-86. PMID 23550006 DOI: 10.1007/978-1-4614-6199-9_8 |
0.307 |
|
2013 |
Ubuka T, Son YL, Bentley GE, Millar RP, Tsutsui K. Gonadotropin-inhibitory hormone (GnIH), GnIH receptor and cell signaling. General and Comparative Endocrinology. 190: 10-7. PMID 23499786 DOI: 10.1016/J.Ygcen.2013.02.030 |
0.329 |
|
2013 |
Young J, George JT, Tello JA, Francou B, Bouligand J, Guiochon-Mantel A, Brailly-Tabard S, Anderson RA, Millar RP. Kisspeptin restores pulsatile LH secretion in patients with neurokinin B signaling deficiencies: physiological, pathophysiological and therapeutic implications. Neuroendocrinology. 97: 193-202. PMID 22377698 DOI: 10.1159/000336376 |
0.333 |
|
2012 |
Guerriero KA, Keen KL, Millar RP, Terasawa E. Developmental changes in GnRH release in response to kisspeptin agonist and antagonist in female rhesus monkeys (Macaca mulatta): implication for the mechanism of puberty. Endocrinology. 153: 825-36. PMID 22166978 DOI: 10.1210/En.2011-1565 |
0.34 |
|
2009 |
Roseweir AK, Kauffman AS, Smith JT, Guerriero KA, Morgan K, Pielecka-Fortuna J, Pineda R, Gottsch ML, Tena-Sempere M, Moenter SM, Terasawa E, Clarke IJ, Steiner RA, Millar RP. Discovery of potent kisspeptin antagonists delineate physiological mechanisms of gonadotropin regulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 3920-9. PMID 19321788 DOI: 10.1523/Jneurosci.5740-08.2009 |
0.313 |
|
2008 |
Hamid T, Malik MT, Millar RP, Kakar SS. Protein kinase A serves as a primary pathway in activation of Nur77 expression by gonadotropin-releasing hormone in the LbetaT2 mouse pituitary gonadotroph tumor cell line. International Journal of Oncology. 33: 1055-64. PMID 18949369 |
0.306 |
|
2008 |
López de Maturana R, Pawson AJ, Lu ZL, Davidson L, Maudsley S, Morgan K, Langdon SP, Millar RP. Gonadotropin-releasing hormone analog structural determinants of selectivity for inhibition of cell growth: support for the concept of ligand-induced selective signaling. Molecular Endocrinology (Baltimore, Md.). 22: 1711-22. PMID 18467526 DOI: 10.1210/Me.2006-0537 |
0.321 |
|
2008 |
White CD, Stewart AJ, Lu ZL, Millar RP, Morgan K. Antiproliferative effects of GnRH agonists: prospects and problems for cancer therapy. Neuroendocrinology. 88: 67-79. PMID 18309229 DOI: 10.1159/000119093 |
0.324 |
|
2008 |
Smith JT, Rao A, Pereira A, Caraty A, Millar RP, Clarke IJ. Kisspeptin is present in ovine hypophysial portal blood but does not increase during the preovulatory luteinizing hormone surge: evidence that gonadotropes are not direct targets of kisspeptin in vivo. Endocrinology. 149: 1951-9. PMID 18162520 DOI: 10.1210/En.2007-1425 |
0.342 |
|
2008 |
Small TW, Sharp PJ, Bentley GE, Millar RP, Tsutsui K, Mura E, Deviche P. Photoperiod-independent hypothalamic regulation of luteinizing hormone secretion in a free-living Sonoran desert bird, the Rufous-winged Sparrow (Aimophila carpalis). Brain, Behavior and Evolution. 71: 127-42. PMID 18032888 DOI: 10.1159/000111459 |
0.321 |
|
2008 |
Millar RP, Pawson AJ, Morgan K, Rissman EF, Lu ZL. Diversity of actions of GnRHs mediated by ligand-induced selective signaling. Frontiers in Neuroendocrinology. 29: 17-35. PMID 17976709 DOI: 10.1016/j.yfrne.2007.06.002 |
0.334 |
|
2008 |
Stewart AJ, Sellar R, Wilson DJ, Millar RP, Lu ZL. Identification of a novel ligand binding residue Arg38(1.35) in the human gonadotropin-releasing hormone receptor. Molecular Pharmacology. 73: 75-81. PMID 17942747 DOI: 10.1124/mol.107.040816 |
0.309 |
|
2008 |
Sun Y-, Dunn IC, Baines E, Talbot RT, Illing N, Millar RP, Sharp PJ. Distribution and Regulation by Oestrogen of Fully Processed and Variant Transcripts of Gonadotropin Releasing Hormone I and Gonadotropin Releasing Hormone Receptor mRNAs in the Male Chicken: Chicken GnRH I and GnRH receptor mRNAs Journal of Neuroendocrinology. 13: 37-49. DOI: 10.1111/J.1365-2826.2001.00587.X |
0.337 |
|
2007 |
Naor Z, Jabbour HN, Naidich M, Pawson AJ, Morgan K, Battersby S, Millar MR, Brown P, Millar RP. Reciprocal cross talk between gonadotropin-releasing hormone (GnRH) and prostaglandin receptors regulates GnRH receptor expression and differential gonadotropin secretion. Molecular Endocrinology (Baltimore, Md.). 21: 524-37. PMID 17138645 DOI: 10.1210/me.2006-0253 |
0.337 |
|
2006 |
Meddle SL, Bush S, Sharp PJ, Millar RP, Wingfield JC. Hypothalamic pro-GnRH-GAP, GnRH-I and GnRH-II during the onset of photorefractoriness in the white-crowned sparrow (Zonotrichia leucophrys gambelii). Journal of Neuroendocrinology. 18: 217-26. PMID 16454805 DOI: 10.1111/j.1365-2826.2005.01403.x |
0.335 |
|
2005 |
Millar R. [Recent data on GnRH receptors]. Annales D'Urologie. S32-6. PMID 16302708 DOI: 10.1016/s0003-4401(05)80005-1 |
0.304 |
|
2005 |
Millar RP. GnRHs and GnRH receptors. Animal Reproduction Science. 88: 5-28. PMID 16140177 DOI: 10.1016/J.ANIREPROSCI.2005.05.032 |
0.347 |
|
2005 |
Soga T, Ogawa S, Millar RP, Sakuma Y, Parhar IS. Localization of the three GnRH types and GnRH receptors in the brain of a cichlid fish: Insights into their neuroendocrine and neuromodulator functions. The Journal of Comparative Neurology. 487: 28-41. PMID 15861460 DOI: 10.1002/cne.20519 |
0.334 |
|
2004 |
Maudsley S, Davidson L, Pawson AJ, Chan R, López de Maturana R, Millar RP. Gonadotropin-releasing hormone (GnRH) antagonists promote proapoptotic signaling in peripheral reproductive tumor cells by activating a Galphai-coupling state of the type I GnRH receptor. Cancer Research. 64: 7533-44. PMID 15492280 DOI: 10.1158/0008-5472.CAN-04-1360 |
0.342 |
|
2004 |
Millar RP, Lu ZL, Pawson AJ, Flanagan CA, Morgan K, Maudsley SR. Gonadotropin-releasing hormone receptors. Endocrine Reviews. 25: 235-75. PMID 15082521 DOI: 10.1210/er.2003-0002 |
0.322 |
|
2003 |
De Groef B, Geris KL, Manzano J, Bernal J, Millar RP, Abou-Samra AB, Porter TE, Iwasawa A, Kühn ER, Darras VM. Involvement of thyrotropin-releasing hormone receptor, somatostatin receptor subtype 2 and corticotropin-releasing hormone receptor type 1 in the control of chicken thyrotropin secretion Molecular and Cellular Endocrinology. 203: 33-39. PMID 12782401 DOI: 10.1016/S0303-7207(03)00120-5 |
0.349 |
|
2002 |
Parhar IS, Soga T, Sakuma Y, Millar RP. Spatio-temporal expression of gonadotropin-releasing hormone receptor subtypes in gonadotropes, somatotropes and lactotropes in the cichlid fish. Journal of Neuroendocrinology. 14: 657-65. PMID 12153468 DOI: 10.1046/j.1365-2826.2002.00817.x |
0.355 |
|
2001 |
Robison RR, White RB, Illing N, Troskie BE, Morley M, Millar RP, Fernald RD. Gonadotropin-releasing hormone receptor in the teleost Haplochromis burtoni: structure, location, and function. Endocrinology. 142: 1737-43. PMID 11316736 DOI: 10.1210/Endo.142.5.8155 |
0.31 |
|
2000 |
Millar RP, Zhu YF, Struthers RS. Progress towards the development of non-peptide orally-active gonadotropin-releasing hormone (GnRH) antagonists: Therapeutic implications British Medical Bulletin. 56: 761-772. PMID 11255560 DOI: 10.1258/0007142001903346 |
0.332 |
|
2000 |
Yoo MS, Kang HM, Choi HS, Kim JW, Troskie BE, Millar RP, Kwon HB. Molecular cloning, distribution and pharmacological characterization of a novel gonadotropin-releasing hormone ([Trp8] GnRH) in frog brain. Molecular and Cellular Endocrinology. 164: 197-204. PMID 11026571 DOI: 10.1016/S0303-7207(00)00221-5 |
0.374 |
|
2000 |
Troskie BE, Hapgood JP, Millar RP, Illing N. Complementary deoxyribonucleic acid cloning, gene expression, and ligand selectivity of a novel gonadotropin-releasing hormone receptor expressed in the pituitary and midbrain of Xenopus laevis. Endocrinology. 141: 1764-1771. PMID 10803587 DOI: 10.1210/Endo.141.5.7453 |
0.307 |
|
1999 |
Illing N, Troskie BE, Nahorniak CS, Hapgood JP, Peter RE, Millar RP. Two gonadotropin-releasing hormone receptor subtypes with distinct ligand selectivity and differential distribution in brain and pituitary in the goldfish (Carassius auratus) Proceedings of the National Academy of Sciences of the United States of America. 96: 2526-2531. PMID 10051676 DOI: 10.1073/Pnas.96.5.2526 |
0.365 |
|
1998 |
Pawson AJ, Katz A, Sun YM, Lopes J, Illing N, Millar RP, Davidson JS. Contrasting internalization kinetics of human and chicken gonadotropin-releasing hormone receptors mediated by C-terminal tail. The Journal of Endocrinology. 156: R9-12. PMID 9582516 DOI: 10.1677/Joe.0.156R009 |
0.303 |
|
1997 |
Flanagan CA, Millar RP, Illing N. Advances in understanding gonadotrophin-releasing hormone receptor structure and ligand interactions. Reviews of Reproduction. 2: 113-20. PMID 9414473 DOI: 10.1530/Ror.0.0020113 |
0.327 |
|
1996 |
Davidson JS, Flanagan CA, Davies PD, Hapgood J, Myburgh D, Elario R, Millar RP, Forrest-Owen W, McArdle CA. Incorporation of an additional glycosylation site enhances expression of functional human gonadotropin-releasing hormone receptor. Endocrine. 4: 207-12. PMID 21153276 DOI: 10.1007/BF02738686 |
0.301 |
|
1996 |
Flanagan CA, Tetaz T, Smith AI, Millar RP. Development of methods for purification of membrane associated gonadotropin-releasing hormone binding proteins. Biomedical Chromatography : Bmc. 10: 83-8. PMID 8924732 DOI: 10.1002/(SICI)1099-0801(199603)10:2<83::AID-BMC563>3.0.CO;2-Z |
0.312 |
|
1995 |
Sealfon SC, Millar RP. The gonadotrophin-releasing hormone receptor: Structural determinants and regulatory control Human Reproduction Update. 1: 216-230. PMID 9187940 DOI: 10.1093/Humupd/1.3.216 |
0.307 |
|
1995 |
Jacobs GF, Flanagan CA, Roeske RW, Millar RP. Agonist activity of mammalian gonadotropin-releasing antagonists in chicken gonadotropes reflects marked differences in vertebrate gonadotropin-releasing receptors. Molecular and Cellular Endocrinology. 108: 107-13. PMID 7758822 DOI: 10.1016/0303-7207(94)03463-4 |
0.31 |
|
1995 |
King JA, Millar RP. Evolutionary aspects of gonadotropin-releasing hormone and its receptor. Cellular and Molecular Neurobiology. 15: 5-23. PMID 7648610 DOI: 10.1007/BF02069556 |
0.339 |
|
1995 |
Montero M, Le Belle N, King JA, Millar RP, Dufour S. Differential regulation of the two forms of gonadotropin-releasing hormone (mGnRH and cGnRH-II) by sex steroids in the European female silver eel (Anguilla anguilla). Neuroendocrinology. 61: 525-35. PMID 7617130 DOI: 10.1159/000126876 |
0.301 |
|
1994 |
Davidson JS, Flanagan CA, Becker II, Illing N, Sealfon SC, Millar RP. Molecular function of the gonadotropin-releasing hormone receptor: insights from site-directed mutagenesis. Molecular and Cellular Endocrinology. 100: 9-14. PMID 8056165 DOI: 10.1016/0303-7207(94)90271-2 |
0.302 |
|
1994 |
Davidson JS, Wakefield IK, Millar RP. Absence of rapid desensitization of the mouse gonadotropin-releasing hormone receptor. The Biochemical Journal. 300: 299-302. PMID 8002931 DOI: 10.1042/BJ3000299 |
0.334 |
|
1994 |
Joss JM, King JA, Millar RP. Identification of the molecular forms of and steroid hormone response to gonadotropin-releasing hormone in the Australian lungfish, Neoceratodus forsteri. General and Comparative Endocrinology. 96: 392-400. PMID 7883146 DOI: 10.1006/gcen.1994.1195 |
0.308 |
|
1994 |
Flanagan C, Becker I, Davidson J, Wakefield I, Zhou W, Sealfon S, Millar R. Glutamate 301 of the mouse gonadotropin-releasing hormone receptor confers specificity for arginine 8 of mammalian gonadotropin-releasing hormone. Journal of Biological Chemistry. 269: 22636-22641. DOI: 10.1016/S0021-9258(17)31693-9 |
0.325 |
|
1993 |
Illing N, Jacobs GF, Becker II, Flanagan CA, Davidson JS, Eales A, Zhou W, Sealfon SC, Millar RP. Comparative sequence analysis and functional characterization of the cloned sheep gonadotropin-releasing hormone receptor reveal differences in primary structure and ligand specificity among mammalian receptors. Biochemical and Biophysical Research Communications. 196: 745-51. PMID 7694577 DOI: 10.1006/Bbrc.1993.2312 |
0.302 |
|
1992 |
Habibi HR, Peter RE, Nahorniak CS, Milton RC, Millar RP. Activity of vertebrate gonadotropin-releasing hormones and analogs with variant amino acid residues in positions 5, 7 and 8 in the goldfish pituitary. Regulatory Peptides. 37: 271-84. PMID 1313596 DOI: 10.1016/0167-0115(92)90620-A |
0.339 |
|
1992 |
King JA, Millar RP. Evolution of gonadotropin-releasing hormones Trends in Endocrinology and Metabolism. 3: 339-346. DOI: 10.1016/1043-2760(92)90113-F |
0.308 |
|
1990 |
van der Merwe PA, Millar RP, Wakefield IK, Macrae MB, Davidson JS. Staurosporine enhances gonadotrophin-releasing hormone-stimulated luteinizing hormone secretion. Febs Letters. 267: 111-3. PMID 2163893 DOI: 10.1016/0014-5793(90)80301-X |
0.304 |
|
1989 |
Thomas GB, Cummins JT, Doughton BW, Griffin N, Millar RP, Milton RC, Clarke IJ. Gonadotropin-releasing hormone associated peptide (GAP) and putative processed GAP peptides do not release luteinizing hormone or follicle-stimulating hormone or inhibit prolactin secretion in the sheep. Neuroendocrinology. 48: 342-50. PMID 3145468 DOI: 10.1159/000125033 |
0.331 |
|
1989 |
King JA, Davidson JS, Mehl AE, Wakefield IK, Andersson PB, Millar RP. Gonadal steroid modulation of signal transduction and luteinizing hormone release in cultured chicken pituitary cells. Endocrinology. 124: 1830-40. PMID 2538311 DOI: 10.1210/ENDO-124-4-1830 |
0.327 |
|
1988 |
King JA, Davidson JS, Millar RP. Interaction of endogenous chicken gonadotrophin-releasing hormone-I and -II on chicken pituitary cells. The Journal of Endocrinology. 117: 43-9. PMID 3282021 DOI: 10.1677/JOE.0.1170043 |
0.366 |
|
1988 |
King JA, Hassan MF, Mehl AE, Millar RP. Gonadotropin-releasing hormone molecular forms in mammalian hypothalamus. Endocrinology. 122: 2742-52. PMID 3131123 DOI: 10.1210/endo-122-6-2742 |
0.329 |
|
1987 |
Licht P, Porter D, Millar RP. Specificity of amphibian and reptilian pituitaries for various forms of gonadotropin-releasing hormones in vitro. General and Comparative Endocrinology. 66: 248-55. PMID 3556314 DOI: 10.1016/0016-6480(87)90274-7 |
0.354 |
|
1987 |
Peter RE, Nahorniak CS, Shih S, King JA, Millar RP. Activity of position-8-substituted analogs of mammalian gonadotropin-releasing hormone (mGnRH) and chicken and lamprey gonadotropin-releasing hormones in goldfish. General and Comparative Endocrinology. 65: 385-93. PMID 3549438 DOI: 10.1016/0016-6480(87)90123-7 |
0.307 |
|
1987 |
Sower SA, King JA, Millar RP, Sherwood NM, Marshak DR. Comparative biological properties of lamprey gonadotropin-releasing hormone in vertebrates. Endocrinology. 120: 773-9. PMID 3542509 DOI: 10.1210/Endo-120-2-773 |
0.33 |
|
1987 |
Milton SC, Millar RP, Milton RC. LH-releasing activity and receptor binding of pHGnRH 14-26 analogues. Biochemical and Biophysical Research Communications. 143: 872-9. PMID 3032187 DOI: 10.1016/0006-291X(87)90330-5 |
0.334 |
|
1986 |
King JA, Millar RP. Identification of His5, Trp7, Tyr8-GnRH (chicken GnRH II) in amphibian brain Peptides. 7: 827-834. PMID 3540909 DOI: 10.1016/0196-9781(86)90102-6 |
0.326 |
|
1986 |
Powell RC, Millar RP, King JA. Diverse molecular forms of gonadotropin-releasing hormone in an elasmobranch and a teleost fish. General and Comparative Endocrinology. 63: 77-85. PMID 3533711 DOI: 10.1016/0016-6480(86)90184-X |
0.322 |
|
1986 |
Sharp PJ, Sterling RJ, Milton RC, Millar RP. Effect of luteinising hormone releasing hormone and its analogues on plasma luteinising hormone concentrations in incubating bantam hens. British Poultry Science. 27: 129-35. PMID 3518873 DOI: 10.1080/00071668608416864 |
0.301 |
|
1986 |
King JA, Davidson JS, Millar RP. Desensitization to gonadotropin-releasing hormone in perifused chicken anterior pituitary cells. Endocrinology. 119: 1510-8. PMID 3093193 DOI: 10.1210/ENDO-119-4-1510 |
0.306 |
|
1986 |
Millar RP, Milton RC, Follett BK, King JA. Receptor binding and gonadotropin-releasing activity of a novel chicken gonadotropin-releasing hormone ([His5, Trp7, Tyr8]GnRH) and a D-Arg6 analog. Endocrinology. 119: 224-31. PMID 3013586 DOI: 10.1210/ENDO-119-1-224 |
0.33 |
|
1984 |
Licht P, Millar R, King JA, McCreery BR, Mendonca MT, Bona-Gallo A, Lofts B. Effects of chicken and mammalian gonadotropin-releasing hormones (GnRH) on in vivo pituitary gonadotropin release in amphibians and reptiles. General and Comparative Endocrinology. 54: 89-96. PMID 6427062 DOI: 10.1016/0016-6480(84)90203-X |
0.335 |
|
1984 |
King JA, Tobler CJ, Roeske RW, Day WA, Rivier JE, Millar RP. A radioimmunoassay specific for [Gln8]LH-RH: application in the confirmation of the structure of chicken hypothalamic luteinizing hormone-releasing hormone. Peptides. 4: 883-7. PMID 6369269 DOI: 10.1016/0196-9781(83)90086-4 |
0.312 |
|
1983 |
Millar RP, King JA. Synthesis and biological activity of [D-Trp6] chicken luteinizing hormone-releasing hormone Peptides. 4: 425-429. PMID 6316292 DOI: 10.1016/0196-9781(83)90044-X |
0.33 |
|
1983 |
Millar RP, King JA. Synthesis, luteinizing hormone-releasing activity, and receptor binding of chicken hypothalamic luteinizing hormone-releasing hormone Endocrinology. 113: 1364-1369. PMID 6311518 DOI: 10.1210/ENDO-113-4-1364 |
0.345 |
|
1983 |
de L Milton RC, King JA, Badminton MN, Tobler CJ, Lindsey GG, Fridkin M, Millar RP. Comparative structure-activity studies on mammalian [Arg8] LH-RH and chicken [Gln8] LH-RH by fluorimetric titration. Biochemical and Biophysical Research Communications. 111: 1082-8. PMID 6301482 DOI: 10.1016/0006-291X(83)91410-9 |
0.344 |
|
1981 |
King JA, Millar RP. Decapeptide luteinizing hormone releasing hormone in ovine pineal gland Journal of Endocrinology. 91: 405-414. PMID 7035594 DOI: 10.1677/JOE.0.0910405 |
0.303 |
|
1979 |
King JA, Millar RP. Hypothalamic luteinizing hormone-releasing hormone content in relation to the seasonal reproductive cycle of Xenopus laevis General and Comparative Endocrinology. 39: 309-312. PMID 387514 DOI: 10.1016/0016-6480(79)90125-4 |
0.328 |
|
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