Year |
Citation |
Score |
2024 |
Wong RW, Balachandran A, Cheung PK, Cheng R, Pan Q, Stoilov P, Harrigan PR, Blencowe BJ, Branch DR, Cochrane A. Correction: An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing. Plos Pathogens. 20: e1012155. PMID 38593115 DOI: 10.1371/journal.ppat.1012155 |
0.515 |
|
2023 |
Jahanshahi S, Ouyang H, Ahmed C, Zahedi Amiri A, Dahal S, Mao YQ, Van Ommen DAJ, Malty R, Duan W, Been T, Hernandez J, Mangos M, Nurtanto J, Babu M, Attisano L, ... ... Cochrane A, et al. Broad spectrum post-entry inhibitors of coronavirus replication: Cardiotonic steroids and monensin. Virology. 589: 109915. PMID 37931588 DOI: 10.1016/j.virol.2023.109915 |
0.347 |
|
2023 |
Dahal S, Clayton K, Cabral T, Cheng R, Jahanshahi S, Ahmed C, Koirala A, Villasmil Ocando A, Malty R, Been T, Hernandez J, Mangos M, Shen D, Babu M, Calarco J, ... ... Cochrane A, et al. On a path toward a broad-spectrum anti-viral: inhibition of HIV-1 and coronavirus replication by SR kinase inhibitor harmine. Journal of Virology. e0039623. PMID 37706687 DOI: 10.1128/jvi.00396-23 |
0.645 |
|
2023 |
Monette A, Niu M, Kaddis Maldonado R, Chang J, Lambert GS, Flanagan JM, Cochrane A, Parent LJ, Mouland AJ. Influence of HIV-1 genomic RNA on the formation of Gag biomolecular condensates. Journal of Molecular Biology. 168190. PMID 37385580 DOI: 10.1016/j.jmb.2023.168190 |
0.569 |
|
2023 |
Monette A, Niu M, Maldonado RK, Chang J, Lambert GS, Flanagan JM, Cochrane A, Parent LJ, Mouland AJ. Influence of HIV-1 genomic RNA on the formation of Gag biomolecular condensates. Biorxiv : the Preprint Server For Biology. PMID 36865181 DOI: 10.1101/2023.02.23.529585 |
0.568 |
|
2022 |
Chau BA, Chen V, Cochrane AW, Parent LJ, Mouland AJ. Liquid-liquid phase separation of nucleocapsid proteins during SARS-CoV-2 and HIV-1 replication. Cell Reports. 42: 111968. PMID 36640305 DOI: 10.1016/j.celrep.2022.111968 |
0.341 |
|
2022 |
Dahal S, Clayton K, Been T, Fernet-Brochu R, Ocando AV, Balachandran A, Poirier M, Maldonado RK, Shkreta L, Boligan KF, Guvenc F, Rahman F, Branch D, Bell B, Chabot B, ... ... Cochrane A, et al. Opposing roles of CLK SR kinases in controlling HIV-1 gene expression and latency. Retrovirology. 19: 18. PMID 35986377 DOI: 10.1186/s12977-022-00605-4 |
0.629 |
|
2021 |
Dahal S, Cheng R, Cheung PK, Been T, Malty R, Geng M, Manianis S, Shkreta L, Jahanshahi S, Toutant J, Chan R, Park S, Brockman MA, Babu M, Mubareka S, ... ... Cochrane A, et al. The Thiazole-5-Carboxamide GPS491 Inhibits HIV-1, Adenovirus, and Coronavirus Replication by Altering RNA Processing/Accumulation. Viruses. 14. PMID 35062264 DOI: 10.3390/v14010060 |
0.644 |
|
2021 |
Zamiri M, Cheung PK, Brockman MA, Brumme ZL, Chabot B, Cochrane A, Grierson DS. 2-Trifluoromethylthiazole-5-carboxamides: Analogues of a Stilbene-Based Anti-HIV Agent that Impact HIV mRNA Processing. Acs Medicinal Chemistry Letters. 12: 1818-1823. PMID 34795872 DOI: 10.1021/acsmedchemlett.1c00428 |
0.579 |
|
2021 |
Schonhofer C, Yi J, Sciorillo A, Andrae-Marobela K, Cochrane A, Harris M, Brumme ZL, Brockman MA, Mounzer K, Hart C, Gyampoh K, Yuan Z, Montaner LJ, Tietjen I. Flavonoid-based inhibition of cyclin-dependent kinase 9 without concomitant inhibition of histone deacetylases durably reinforces HIV latency. Biochemical Pharmacology. 114462. PMID 33577894 DOI: 10.1016/j.bcp.2021.114462 |
0.549 |
|
2020 |
Tuffy KM, Maldonado RJK, Chang J, Rosenfeld P, Cochrane A, Parent LJ. HIV-1 Gag Forms Ribonucleoprotein Complexes with Unspliced Viral RNA at Transcription Sites. Viruses. 12. PMID 33182496 DOI: 10.3390/v12111281 |
0.625 |
|
2020 |
Wong RW, Balachandran A, Cheung PK, Cheng R, Pan Q, Stoilov P, Harrigan PR, Blencowe BJ, Branch DR, Cochrane A. An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing. Plos Pathogens. 16: e1008307. PMID 32069328 DOI: 10.1371/Journal.Ppat.1008307 |
0.716 |
|
2019 |
Wong RW, Lingwood CA, Ostrowski MA, Cabral T, Cochrane A. Author Correction: Cardiac glycoside/aglycones inhibit HIV-1 gene expression by a mechanism requiring MEK1/2-ERK1/2 signaling. Scientific Reports. 9: 18656. PMID 31796843 DOI: 10.1038/S41598-019-54732-8 |
0.452 |
|
2019 |
McCarthy SDS, Leontyev D, Nicoletti P, Binnington B, Kozlowski HN, Ostrowski M, Cochrane A, Branch DR, Wong RW. Targeting ABL1 or ARG Tyrosine Kinases to Restrict HIV-1 Infection in Primary CD4+ T-Cells or in Humanized NSG Mice. Journal of Acquired Immune Deficiency Syndromes (1999). 82: 407-415. PMID 31658184 DOI: 10.1097/Qai.0000000000002144 |
0.493 |
|
2019 |
Woolley GA, Lu H, Mazumder M, Jaikaran ASI, Kumar A, Leis E, Xu X, Altmann M, Cochrane A. A yeast system for discovering optogenetic inhibitors of eukaryotic translation initiation. Acs Synthetic Biology. PMID 30901519 DOI: 10.1021/Acssynbio.8B00386 |
0.38 |
|
2018 |
Wong RW, Lingwood CA, Ostrowski MA, Cabral T, Cochrane A. Cardiac glycoside/aglycones inhibit HIV-1 gene expression by a mechanism requiring MEK1/2-ERK1/2 signaling. Scientific Reports. 8: 850. PMID 29339801 DOI: 10.1038/S41598-018-19298-X |
0.675 |
|
2017 |
Balachandran A, Cochrane A. Screening for Small Molecule Inhibitors of HIV-1 Gag Expression. Methods (San Diego, Calif.). PMID 28600226 DOI: 10.1016/J.Ymeth.2017.06.007 |
0.603 |
|
2017 |
Balachandran A, Wong R, Stoilov P, Pan S, Blencowe B, Cheung P, Harrigan PR, Cochrane A. Identification of small molecule modulators of HIV-1 Tat and Rev protein accumulation. Retrovirology. 14: 7. PMID 28122580 DOI: 10.1186/S12977-017-0330-0 |
0.696 |
|
2016 |
Shkreta L, Blanchette M, Toutant J, Wilhelm E, Bell B, Story BA, Balachandran A, Cochrane A, Cheung PK, Harrigan PR, Grierson DS, Chabot B. Modulation of the splicing regulatory function of SRSF10 by a novel compound that impairs HIV-1 replication. Nucleic Acids Research. PMID 27928057 DOI: 10.1093/Nar/Gkw1223 |
0.639 |
|
2016 |
Grosso F, Stoilov P, Lingwood C, Brown M, Cochrane A. Suppression of Adenovirus Replication by Cardiotonic Steroids. Journal of Virology. PMID 27881644 DOI: 10.1128/Jvi.01623-16 |
0.504 |
|
2015 |
Platt C, Calimano M, Nemet J, Bubenik J, Cochrane A. Differential Effects of Tra2ß Isoforms on HIV-1 RNA Processing and Expression. Plos One. 10: e0125315. PMID 25970345 DOI: 10.1371/journal.pone.0125315 |
0.66 |
|
2015 |
Ferreira VH, Dizzell S, Nazli A, Kafka JK, Mueller K, Nguyen PV, Tremblay MJ, Cochrane A, Kaushic C. Medroxyprogesterone Acetate Regulates HIV-1 Uptake and Transcytosis but Not Replication in Primary Genital Epithelial Cells, Resulting in Enhanced T-Cell Infection. The Journal of Infectious Diseases. 211: 1745-56. PMID 25538276 DOI: 10.1093/Infdis/Jiu832 |
0.543 |
|
2015 |
Platt C, Calimano M, Nemet J, Bubenik J, Cochrane A. Differential effects of Tra2β isoforms on HIV-1 RNA processing and expression Plos One. 10. DOI: 10.1371/Journal.Pone.0125315 |
0.708 |
|
2014 |
Cochrane A. HIV-1 Rev function and RNA nuclear-cytoplasmic export. Methods in Molecular Biology (Clifton, N.J.). 1087: 103-14. PMID 24158817 DOI: 10.1007/978-1-62703-670-2_9 |
0.61 |
|
2013 |
Wong RW, Balachandran A, Haaland M, Stoilov P, Cochrane A. Characterization of novel inhibitors of HIV-1 replication that function via alteration of viral RNA processing and rev function Nucleic Acids Research. 41: 9471-9483. PMID 23945945 DOI: 10.1093/Nar/Gkt727 |
0.704 |
|
2013 |
Wong RW, Balachandran A, Ostrowski MA, Cochrane A. Digoxin Suppresses HIV-1 Replication by Altering Viral RNA Processing Plos Pathogens. 9. PMID 23555254 DOI: 10.1371/Journal.Ppat.1003241 |
0.724 |
|
2013 |
Lochmann TL, Bann DV, Ryan EP, Beyer AR, Mao A, Cochrane A, Parent LJ. NC-mediated nucleolar localization of retroviral gag proteins. Virus Research. 171: 304-18. PMID 23036987 DOI: 10.1016/J.Virusres.2012.09.011 |
0.634 |
|
2013 |
Platt C, Calimano M, Nemet J, Bubenik J, Cochrane A. Differential effects of Tra2β isoforms on HIV-1 RNA processing and expression Retrovirology. 10: 17. DOI: 10.1186/1742-4690-10-S1-P17 |
0.683 |
|
2013 |
Wong R, Balachandran A, Haaland M, Stoilov P, Cochrane A. HIV-1 RNA processing as therapeutic target: characterization of small molecule modulators of HIV-1 RNA processing and transport Retrovirology. 10. DOI: 10.1186/1742-4690-10-S1-O45 |
0.678 |
|
2012 |
Sharma A, Yilmaz A, Marsh K, Cochrane A, Boris-Lawrie K. Thriving under stress: selective translation of HIV-1 structural protein mRNA during Vpr-mediated impairment of eIF4E translation activity. Plos Pathogens. 8: e1002612. PMID 22457629 DOI: 10.1371/Journal.Ppat.1002612 |
0.656 |
|
2012 |
Lund N, Milev MP, Wong R, Sanmuganantham T, Woolaway K, Chabot B, Abou Elela S, Mouland AJ, Cochrane A. Differential effects of hnRNP D/AUF1 isoforms on HIV-1 gene expression. Nucleic Acids Research. 40: 3663-75. PMID 22187150 DOI: 10.1093/Nar/Gkr1238 |
0.6 |
|
2011 |
Wong R, Balachandran A, Mao AY, Dobson W, Gray-Owen S, Cochrane A. Differential effect of CLK SR Kinases on HIV-1 gene expression: potential novel targets for therapy. Retrovirology. 8: 47. PMID 21682887 DOI: 10.1186/1742-4690-8-47 |
0.658 |
|
2011 |
Dobson-Belaire WN, Cochrane A, Ostrowski MA, Gray-Owen SD. Differential response of primary and immortalized CD4+ T cells to Neisseria gonorrhoeae-induced cytokines determines the effect on HIV-1 replication. Plos One. 6: e18133. PMID 21526113 DOI: 10.1371/Journal.Pone.0018133 |
0.523 |
|
2009 |
Christie NM, Willer DO, Lobritz MA, Chan JK, Arts EJ, Ostrowski MA, Cochrane A, Luscher MA, MacDonald KS. Viral fitness implications of variation within an immunodominant CD8+ T-cell epitope of HIV-1 Virology. 388: 137-146. PMID 19368950 DOI: 10.1016/J.Virol.2009.03.003 |
0.448 |
|
2009 |
Cochrane A, Murley LL, Gao M, Wong R, Clayton K, Brufatto N, Canadien V, Mamelak D, Chen T, Richards D, Zeghouf M, Greenblatt J, Burks C, Frappier L. Stable complex formation between HIV Rev and the nucleosome assembly protein, NAP1, affects Rev function. Virology. 388: 103-11. PMID 19339032 DOI: 10.1016/J.Virol.2009.03.005 |
0.659 |
|
2009 |
Cochrane A. Inhibition of HIV-1 gene expression by Sam68 Delta C: multiple targets but a common mechanism? Retrovirology. 6: 22. PMID 19254361 DOI: 10.1186/1742-4690-6-22 |
0.646 |
|
2009 |
Cochrane A. How does the journey affect the message(RNA)? Rna Biology. 6: 169-70. PMID 19246987 DOI: 10.4161/Rna.6.2.8095 |
0.578 |
|
2009 |
McLaren M, Cochrane A. Mapping of determinants involved in the stimulation of HIV-1 expression by Sam68. Virology. 385: 93-104. PMID 19091369 DOI: 10.1016/J.Virol.2008.10.049 |
0.696 |
|
2008 |
Marsh K, Soros V, Cochrane A. Selective translational repression of HIV-1 RNA by Sam68DeltaC occurs by altering PABP1 binding to unspliced viral RNA. Retrovirology. 5: 97. PMID 18957126 DOI: 10.1186/1742-4690-5-97 |
0.761 |
|
2008 |
McLaren M, Marsh K, Cochrane A. Modulating HIV-1 RNA processing and utilization. Frontiers in Bioscience. 13: 5693. PMID 18508616 DOI: 10.2741/3110 |
0.695 |
|
2007 |
Woolaway K, Asai K, Emili A, Cochrane A. hnRNP E1 and E2 have distinct roles in modulating HIV-1 gene expression. Retrovirology. 4: 28. PMID 17451601 DOI: 10.1186/1742-4690-4-28 |
0.605 |
|
2007 |
Ao Z, Huang G, Yao H, Xu Z, Labine M, Cochrane AW, Yao X. Interaction of human immunodeficiency virus type 1 integrase with cellular nuclear import receptor importin 7 and its impact on viral replication. The Journal of Biological Chemistry. 282: 13456-67. PMID 17360709 DOI: 10.1074/Jbc.M610546200 |
0.588 |
|
2006 |
Sajic R, Lee K, Asai K, Sakac D, Branch DR, Upton C, Cochrane A. Use of modified U1 snRNAs to inhibit HIV-1 replication. Nucleic Acids Research. 35: 247-55. PMID 17158512 DOI: 10.1093/Nar/Gkl1022 |
0.671 |
|
2006 |
Cochrane AW, McNally MT, Mouland AJ. The retrovirus RNA trafficking granule: from birth to maturity. Retrovirology. 3: 18. PMID 16545126 DOI: 10.1186/1742-4690-3-18 |
0.539 |
|
2005 |
Cochrane A. Controlling HIV-1 Rev function. Current Drug Targets. Immune, Endocrine and Metabolic Disorders. 4: 287-95. PMID 15578979 DOI: 10.2174/1568008043339677 |
0.512 |
|
2004 |
Bériault V, Clément JF, Lévesque K, Lebel C, Yong X, Chabot B, Cohen EA, Cochrane AW, Rigby WF, Mouland AJ. A late role for the association of hnRNP A2 with the HIV-1 hnRNP A2 response elements in genomic RNA, Gag, and Vpr localization. The Journal of Biological Chemistry. 279: 44141-53. PMID 15294897 DOI: 10.1074/Jbc.M404691200 |
0.637 |
|
2004 |
Mclaren M, Asai K, Cochrane A. A novel function for Sam68: Enhancement of HIV-1 RNA 3 end processing Rna. 10: 1119-1129. PMID 15208447 DOI: 10.1261/Rna.5263904 |
0.706 |
|
2003 |
Asai K, Platt C, Cochrane A. Control of HIV-1 env RNA splicing and transport: Investigating the role of hnRNP A1 in exon splicing silencer (ESS3a) function Virology. 314: 229-242. PMID 14517076 DOI: 10.1016/S0042-6822(03)00400-8 |
0.585 |
|
2003 |
Suh D, Seguin B, Atkinson S, Ozdamar B, Staffa A, Emili A, Mouland A, Cochrane A. Mapping of determinants required for the function of the HIV-1 env nuclear retention sequence Virology. 310: 85-99. PMID 12788633 DOI: 10.1016/S0042-6822(03)00073-4 |
0.64 |
|
2003 |
Chen A, Boulton IC, Pongoski J, Cochrane A, Gray-Owen SD. Induction of HIV-1 long terminal repeat-mediated transcription by Neisseria gonorrhoeae. Aids (London, England). 17: 625-8. PMID 12598784 DOI: 10.1097/00002030-200303070-00019 |
0.594 |
|
2002 |
Pongoski J, Asai K, Cochrane A. Positive and negative modulation of human immunodeficiency virus type 1 Rev function by cis and trans regulators of viral RNA splicing. Journal of Virology. 76: 5108-5120. PMID 11967326 DOI: 10.1128/Jvi.76.10.5108-5120.2002 |
0.644 |
|
2001 |
Soros VB, Carvajal HV, Richard S, Cochrane AW. Inhibition of human immunodeficiency virus type 1 Rev function by a dominant-negative mutant of Sam68 through sequestration of unspliced RNA at perinuclear bundles. Journal of Virology. 75: 8203-15. PMID 11483766 DOI: 10.1128/Jvi.75.17.8203-8215.2001 |
0.737 |
|
2001 |
Soros V, Cochrane A. Alterations in HIV-1 Rev Transport in Response to Cell Stress Virology. 280: 199-210. PMID 11162834 DOI: 10.1006/Viro.2000.0752 |
0.725 |
|
2000 |
Derry JJ, Richard S, Valderrama Carvajal H, Ye X, Vasioukhin V, Cochrane AW, Chen T, Tyner AL. Sik (BRK) phosphorylates Sam68 in the nucleus and negatively regulates its RNA binding ability. Molecular and Cellular Biology. 20: 6114-26. PMID 10913193 DOI: 10.1128/Mcb.20.16.6114-6126.2000 |
0.408 |
|
1998 |
Séguin B, Staffa A, Cochrane A. Control of Human Immunodeficiency Virus Type 1 RNA Metabolism: Role of Splice Sites and Intron Sequences in Unspliced Viral RNA Subcellular Distribution Journal of Virology. 72: 9503-9513. PMID 9811683 DOI: 10.1128/Jvi.72.12.9503-9513.1998 |
0.599 |
|
1992 |
Olsen HS, Cochrane AW, Rosen C. Interaction of cellular factors with intragenic Cis-acting repressive sequences within the HIV genome Virology. 191: 709-715. PMID 1448921 DOI: 10.1016/0042-6822(92)90246-L |
0.535 |
|
1991 |
Cochrane AW, Jones KS, Beidas S, Dillon PJ, Skalka AM, Rosen CA. Identification and characterization of intragenic sequences which repress human immunodeficiency virus structural gene expression. Journal of Virology. 65: 5305-13. PMID 1895385 |
0.393 |
|
1990 |
Olsen HS, Nelbock P, Cochrane AW, Rosen CA. Secondary structure is the major determinant for interaction of HIV rev protein with RNA Science. 247: 845-848. PMID 2406903 DOI: 10.1126/Science.2406903 |
0.603 |
|
1990 |
Cochrane AW, Chen CH, Rosen CA. Specific interaction of the human immunodeficiency virus Rev protein with a structured region in the env mRNA Proceedings of the National Academy of Sciences of the United States of America. 87: 1198-1202. PMID 2405396 DOI: 10.1073/pnas.87.3.1198 |
0.427 |
|
1990 |
Cochrane AW, Perkins A, Rosen CA. Identification of sequences important in the nucleolar localization of human immunodeficiency virus rev: Relevance of nucleolar localization to function Journal of Virology. 64: 881-885. PMID 2404140 DOI: 10.1128/jvi.64.2.881-885.1990 |
0.309 |
|
1990 |
Olsen HS, Cochrane AW, Dillon PJ, Nalin CM, Rosen CA. Interaction of the human immunodeficiency virus type 1 Rev protein with a structured region in env mRNA is dependent on multimer formation mediated through a basic stretch of amino acids Genes and Development. 4: 1357-1364. PMID 2227413 DOI: 10.1101/gad.4.8.1357 |
0.562 |
|
1989 |
Cochrane A, Kramer R, Ruben S, Levine J, Rosen CA. The human immunodeficiency virus rev protein is a nuclear phosphoprotein Virology. 171: 264-266. PMID 2741343 DOI: 10.1016/0042-6822(89)90535-7 |
0.317 |
|
1989 |
Cochrane AW, Chen CH, Kramer R, Tomchak L, Rosen CA. Purification of biologically active human immunodeficiency virus rev protein from Escherichia coli Virology. 173: 335-337. PMID 2683363 DOI: 10.1016/0042-6822(89)90252-3 |
0.324 |
|
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