Year |
Citation |
Score |
2021 |
Ruff GL, Murphy KE, Smith ZR, Vertino PM, Murphy PJ. Subtype-Independent ANP32E Reduction During Breast Cancer Progression in Accordance with Chromatin Relaxation. Bmc Cancer. 21: 1342. PMID 34922480 DOI: 10.1186/s12885-021-09077-9 |
0.391 |
|
2021 |
Miyauchi T, Takahashi M, Mitsuzuka K, Saiki Y, Okubo T, Vertino PM, Goto A, Arai Y, Horii A, Fukushige S. Aberrant Hypermethylation-Mediated Suppression of PYCARD Is Extremely Frequent in Prostate Cancer with Gleason Score ≥ 7. Disease Markers. 2021: 8858905. PMID 33628338 DOI: 10.1155/2021/8858905 |
0.356 |
|
2020 |
Summerbell ER, Mouw JK, Bell JSK, Knippler CM, Pedro B, Arnst JL, Khatib TO, Commander R, Barwick BG, Konen J, Dwivedi B, Seby S, Kowalski J, Vertino PM, Marcus AI. Epigenetically heterogeneous tumor cells direct collective invasion through filopodia-driven fibronectin micropatterning. Science Advances. 6: eaaz6197. PMID 32832657 DOI: 10.1126/Sciadv.Aaz6197 |
0.517 |
|
2020 |
Pedro B, Rupji M, Dwivedi B, Kowalski J, Konen JM, Owonikoko TK, Ramalingam SS, Vertino PM, Marcus AI. Prognostic significance of an invasive leader cell-derived mutation cluster on chromosome 16q. Cancer. PMID 32315457 DOI: 10.1002/Cncr.32903 |
0.375 |
|
2019 |
Zoeller EL, Pedro B, Konen J, Dwivedi B, Rupji M, Sundararaman N, Wang L, Horton JR, Zhong C, Barwick BG, Cheng X, Martinez ED, Torres MP, Kowalski J, Marcus AI, ... Vertino PM, et al. Genetic heterogeneity within collective invasion packs drives leader and follower cell phenotypes. Journal of Cell Science. PMID 31515279 DOI: 10.1242/Jcs.231514 |
0.391 |
|
2019 |
Barwick BG, Gupta VA, Vertino PM, Boise LH. Cell of Origin and Genetic Alterations in the Pathogenesis of Multiple Myeloma. Frontiers in Immunology. 10: 1121. PMID 31231360 DOI: 10.3389/Fimmu.2019.01121 |
0.318 |
|
2019 |
Barwick BG, Skerget S, Keats JJ, Auclair D, Lonial S, Boise LH, Vertino PM, Powell DR. Multiple Myeloma Epigenetic Programming Prognostic of Outcome Converges with Loci Reprogrammed in Relapsed/Refractory Disease Blood. 134: 858-858. DOI: 10.1182/Blood-2019-124422 |
0.417 |
|
2019 |
Barwick BG, Powell DR, Penaherrera D, Skerget S, Keats JJ, Auclair D, Lonial S, Boise LH, Vertino PM. Abstract 839: Whole genome DNA methylation analysis of multiple myeloma identifies pervasive hypomethylation and biomarkers of survival Cancer Research. 79: 839-839. DOI: 10.1158/1538-7445.Am2019-839 |
0.468 |
|
2019 |
Pedro BA, Konen J, Summerbell E, Mouw JK, Rupji M, Dwivedi B, Kowalski J, Vertino PM, Marcus AI. Abstract 4590: Dissecting the biology of leader and follower cells in collective cancer invasion Cancer Research. 79: 4590-4590. DOI: 10.1158/1538-7445.Am2019-4590 |
0.407 |
|
2019 |
Summerbell ER, Konen J, Kowalski J, Vertino P, Marcus A. Abstract 178: MYO10 aberrant methylation and overexpression in leader cells regulates lung cancer collective cell invasion and fibronectin patterning Cancer Research. 79: 178-178. DOI: 10.1158/1538-7445.Am2019-178 |
0.49 |
|
2018 |
Horton JR, Woodcock CB, Chen Q, Liu X, Zhang X, Shanks J, Rai G, Mott BT, Jansen DJ, Kales SC, Henderson MJ, Cyr M, Pohida K, Hu X, Shah P, ... ... Vertino PM, et al. Structure-based engineering of irreversible inhibitors against histone lysine demethylase KDM5A. Journal of Medicinal Chemistry. PMID 30392349 DOI: 10.1021/Acs.Jmedchem.8B01219 |
0.335 |
|
2018 |
Sharma NV, Pellegrini KL, Ouellet V, Giuste FO, Ramalingam S, Watanabe K, Adam-Granger E, Fossouo L, You S, Freeman MR, Vertino P, Conneely K, Osunkoya AO, Trudel D, Mes-Masson AM, et al. Identification of the Transcription Factor Relationships Associated with Androgen Deprivation Therapy Response and Metastatic Progression in Prostate Cancer. Cancers. 10. PMID 30314329 DOI: 10.3390/Cancers10100379 |
0.318 |
|
2018 |
Kennedy EM, Powell DR, Li Z, Bell JSK, Barwick BG, Feng H, McCrary MR, Dwivedi B, Kowalski J, Dynan WS, Conneely KN, Vertino PM. Galactic Cosmic Radiation Induces Persistent Epigenome Alterations Relevant to Human Lung Cancer. Scientific Reports. 8: 6709. PMID 29712937 DOI: 10.1038/S41598-018-24755-8 |
0.392 |
|
2018 |
Barwick BG, Auclair D, Blanski A, Kirchhoff M, Docter B, Rohrer DC, Keats JJ, Lonial S, Boise LH, Vertino PM. Whole Genome DNA Methylation Analysis of Commpass Identifies Biomarkers of Multiple Myeloma Survival Blood. 132: 3174-3174. DOI: 10.1182/Blood-2018-99-116875 |
0.454 |
|
2017 |
Konen J, Summerbell E, Dwivedi B, Galior K, Hou Y, Rusnak L, Chen A, Saltz J, Zhou W, Boise LH, Vertino P, Cooper L, Salaita K, Kowalski J, Marcus AI. Image-guided genomics of phenotypically heterogeneous populations reveals vascular signalling during symbiotic collective cancer invasion. Nature Communications. 8: 15078. PMID 28497793 DOI: 10.1038/Ncomms15078 |
0.401 |
|
2017 |
Bell JSK, Vertino PM. Orphan CpG islands define a novel class of highly active enhancers. Epigenetics. 1-16. PMID 28448736 DOI: 10.1080/15592294.2017.1297910 |
0.471 |
|
2017 |
Barwick B, Gupta VA, Auclair D, Keats JJ, Lonial S, Vertino PM, Boise LH. High-Risk Myeloma Is Demarcated By Immunoglobulin Lambda Light Chain Translocations Blood. 130: 1780-1780. DOI: 10.1182/Blood.V130.Suppl_1.1780.1780 |
0.329 |
|
2017 |
Zoeller EL, Konen J, Bell J, Summerbell E, Kowalski J, Marcus A, Vertino P. Abstract 1962: Regulation of invasion by lysine demethylase 5B in non-small cell lung cancer cells Cancer Research. 77: 1962-1962. DOI: 10.1158/1538-7445.Am2017-1962 |
0.391 |
|
2016 |
Wang D, Hashimoto H, Zhang X, Barwick BG, Lonial S, Boise LH, Vertino PM, Cheng X. MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myeloma. Nucleic Acids Research. PMID 27903915 DOI: 10.1093/Nar/Gkw1184 |
0.372 |
|
2016 |
Horton JR, Liu X, Gale M, Wu L, Shanks JR, Zhang X, Webber PJ, Bell JS, Kales SC, Mott BT, Rai G, Jansen DJ, Henderson MJ, Urban DJ, Hall MD, ... ... Vertino PM, et al. Structural Basis for KDM5A Histone Lysine Demethylase Inhibition by Diverse Compounds. Cell Chemical Biology. PMID 27427228 DOI: 10.1016/J.Chembiol.2016.06.006 |
0.336 |
|
2016 |
Scott EC, Gardner EJ, Masood A, Chuang NT, Vertino PM, Devine SE. A hot L1 retrotransposon evades somatic repression and initiates human colorectal cancer. Genome Research. PMID 27197217 DOI: 10.1101/Gr.201814.115 |
0.339 |
|
2016 |
Bell JS, Kagey JD, Barwick BG, Dwivedi B, McCabe MT, Kowalski J, Vertino PM. Factors affecting the Persistence of Drug-induced Reprogramming of the Cancer Methylome. Epigenetics. 0. PMID 27082926 DOI: 10.1080/15592294.2016.1158364 |
0.787 |
|
2016 |
Kowalski J, Dwivedi B, Newman S, Switchenko JM, Pauly R, Gutman DA, Arora J, Gandhi K, Ainslie K, Doho G, Qin Z, Moreno CS, Rossi MR, Vertino PM, Lonial S, et al. Gene integrated set profile analysis: a context-based approach for inferring biological endpoints. Nucleic Acids Research. PMID 26826710 DOI: 10.1093/Nar/Gkv1503 |
0.302 |
|
2016 |
Bell JS, Kellner WA, Vertino PM. Abstract PR08: GC skew defines distinct RNA polymerase pause sites in CpG island promoters Cancer Research. 76. DOI: 10.1158/1538-7445.Chromepi15-Pr08 |
0.46 |
|
2016 |
Kennedy E, Powell DR, Li Z, Bell JSK, Feng H, Dynan W, Dwivedi B, Kowalski J, Conneely KN, Vertino PM. Abstract B08: Space radiation exposure induces stable epigenome alterations relevant to human lung cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Chromepi15-B08 |
0.403 |
|
2015 |
Horton JR, Engstrom A, Zoeller EL, Liu X, Shanks JR, Zhang X, Johns MA, Vertino PM, Fu H, Cheng X. Characterization of a linked Jumonji domain of the KDM5/JARID1 family of histone H3 lysine 4 demethylases. The Journal of Biological Chemistry. PMID 26645689 DOI: 10.1074/Jbc.M115.698449 |
0.326 |
|
2015 |
Brodie SA, Li G, Harvey D, Khuri FR, Vertino PM, Brandes JC. Small molecule inhibition of the CHFR-PARP1 interaction as novel approach to overcome intrinsic taxane resistance in cancer. Oncotarget. 6: 30773-86. PMID 26356822 DOI: 10.18632/Oncotarget.5040 |
0.343 |
|
2015 |
Kellner WA, Bell JS, Vertino PM. GC skew defines distinct RNA polymerase pause sites in CpG island promoters. Genome Research. 25: 1600-9. PMID 26275623 DOI: 10.1101/Gr.189068.114 |
0.414 |
|
2015 |
Farkas AE, Hilgarth RS, Capaldo CT, Gerner-Smidt C, Powell DR, Vertino PM, Koval M, Parkos CA, Nusrat A. HNF4α regulates claudin-7 protein expression during intestinal epithelial differentiation. The American Journal of Pathology. 185: 2206-18. PMID 26216285 DOI: 10.1016/J.Ajpath.2015.04.023 |
0.349 |
|
2015 |
Hashimoto H, Zhang X, Vertino PM, Cheng X. The Mechanisms of Generation, Recognition, and Erasure of DNA 5-Methylcytosine and Thymine Oxidations. The Journal of Biological Chemistry. 290: 20723-33. PMID 26152719 DOI: 10.1074/Jbc.R115.656884 |
0.391 |
|
2015 |
Stoyanov E, Ludwig G, Mizrahi L, Olam D, Schnitzer-Perlman T, Tasika E, Sass G, Tiegs G, Jiang Y, Nie T, Kohler J, Schinazi RF, Vertino PM, Cedar H, Galun E, et al. Chronic liver inflammation modifies DNA methylation at the precancerous stage of murine hepatocarcinogenesis. Oncotarget. 6: 11047-60. PMID 25918251 DOI: 10.18632/Oncotarget.3567 |
0.323 |
|
2015 |
Gaudette BT, Dwivedi B, Chitta KS, Poulain S, Powell D, Vertino P, Leleu X, Lonial S, Chanan-Khan AA, Kowalski J, Boise LH. Low expression of pro-apoptotic Bcl-2 family proteins sets the apoptotic threshold in Waldenström macroglobulinemia. Oncogene. PMID 25893290 DOI: 10.1038/Onc.2015.103 |
0.33 |
|
2014 |
Brodie SA, Lombardo C, Li G, Kowalski J, Gandhi K, You S, Khuri FR, Marcus A, Vertino PM, Brandes JC. Aberrant promoter methylation of caveolin-1 is associated with favorable response to taxane-platinum combination chemotherapy in advanced NSCLC. Plos One. 9: e107124. PMID 25222296 DOI: 10.1371/Journal.Pone.0107124 |
0.41 |
|
2014 |
Smith AK, Conneely KN, Pace TW, Mister D, Felger JC, Kilaru V, Akel MJ, Vertino PM, Miller AH, Torres MA. Epigenetic changes associated with inflammation in breast cancer patients treated with chemotherapy. Brain, Behavior, and Immunity. 38: 227-36. PMID 24583204 DOI: 10.1016/J.Bbi.2014.02.010 |
0.517 |
|
2014 |
Kapoor-Vazirani P, Vertino PM. A dual role for the histone methyltransferase PR-SET7/SETD8 and histone H4 lysine 20 monomethylation in the local regulation of RNA polymerase II pausing. The Journal of Biological Chemistry. 289: 7425-37. PMID 24459145 DOI: 10.1074/Jbc.M113.520783 |
0.371 |
|
2014 |
Brodie SA, Li G, El-Kommos A, Kang H, Ramalingam SS, Behera M, Gandhi K, Kowalski J, Sica GL, Khuri FR, Vertino PM, Brandes JC. Class I HDACs are mediators of smoke carcinogen-induced stabilization of DNMT1 and serve as promising targets for chemoprevention of lung cancer. Cancer Prevention Research (Philadelphia, Pa.). 7: 351-61. PMID 24441677 DOI: 10.1158/1940-6207.Capr-13-0254 |
0.477 |
|
2014 |
Zoeller EL, Barsyte-Lovejoy D, Brown PJ, Owen DR, Arrowsmith CH, Vertino PM. Abstract 2105: Regulation of estrogen receptor turnover by lysine 302 methylation Cancer Research. 74: 2105-2105. DOI: 10.1158/1538-7445.Am2014-2105 |
0.517 |
|
2013 |
Yang Z, Garcia A, Xu S, Powell DR, Vertino PM, Singh S, Marcus AI. Withania somnifera root extract inhibits mammary cancer metastasis and epithelial to mesenchymal transition. Plos One. 8: e75069. PMID 24069380 DOI: 10.1371/Journal.Pone.0075069 |
0.462 |
|
2013 |
Zhou W, Marcus AI, Vertino PM. Dysregulation of mTOR activity through LKB1 inactivation. Chinese Journal of Cancer. 32: 427-33. PMID 23668926 DOI: 10.5732/Cjc.013.10086 |
0.402 |
|
2013 |
Brodie SA, Li G, El-Kommos A, Ramalingam SS, Behera M, Kowalski J, Gandhi K, Khuri FH, Vertino P, Brandes JC. Abstract B30: Class I HDACs are mediators of smoke-carcinogen induced stabilization of DNMT1 and serve as promising targets for chemoprevention of lung cancer Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-B30 |
0.475 |
|
2013 |
Kapoor P, Vertino PM. Abstract A57: Dual role of the histone methyltransferase PR-SET7/SETD8 in the local regulation of Pol II promoter-proximal pausing Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-A57 |
0.469 |
|
2012 |
Duncan CG, Barwick BG, Jin G, Rago C, Kapoor-Vazirani P, Powell DR, Chi JT, Bigner DD, Vertino PM, Yan H. A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation. Genome Research. 22: 2339-55. PMID 22899282 DOI: 10.1101/Gr.132738.111 |
0.463 |
|
2012 |
Vertino PM, Wade PA. R loops: lassoing DNA methylation at CpGi. Molecular Cell. 45: 708-9. PMID 22464440 DOI: 10.1016/J.Molcel.2012.03.014 |
0.364 |
|
2012 |
Hashimoto H, Liu Y, Upadhyay AK, Chang Y, Howerton SB, Vertino PM, Zhang X, Cheng X. Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation. Nucleic Acids Research. 40: 4841-9. PMID 22362737 DOI: 10.1093/Nar/Gks155 |
0.331 |
|
2012 |
Kowalski J, Gandhi K, Switchenko J, Liu Y, Kim S, Doho G, Kim SJ, Yang R, Chen L, Qin Z, Newman S, Moreno CS, Vertino PM, Bernal-Mizrachi L, Rossi MR, et al. Integrative, Multi-Platform, Whole-Genome Analyses Identify Clinically Relevant Common- and Cell-Specific Signatures in Multiple Myeloma Blood. 120: 3974-3974. DOI: 10.1182/Blood.V120.21.3974.3974 |
0.393 |
|
2012 |
Abreu E, Patel P, Kline E, Marcus A, Vertino P. Abstract 3246: TMS1 / ASC is critical for primary ciliogenesis and participates in cell migration Cancer Research. 72: 3246-3246. DOI: 10.1158/1538-7445.Am2012-3246 |
0.784 |
|
2011 |
Zhu D, Hunter SB, Vertino PM, Van Meir EG. Overexpression of MBD2 in glioblastoma maintains epigenetic silencing and inhibits the antiangiogenic function of the tumor suppressor gene BAI1. Cancer Research. 71: 5859-70. PMID 21724586 DOI: 10.1158/0008-5472.Can-11-1157 |
0.466 |
|
2011 |
Thaiparambil JT, Bender L, Ganesh T, Kline E, Patel P, Liu Y, Tighiouart M, Vertino PM, Harvey RD, Garcia A, Marcus AI. Withaferin A inhibits breast cancer invasion and metastasis at sub-cytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation. International Journal of Cancer. Journal International Du Cancer. 129: 2744-55. PMID 21538350 DOI: 10.1002/Ijc.25938 |
0.777 |
|
2011 |
Kapoor-Vazirani P, Kagey JD, Vertino PM. SUV420H2-mediated H4K20 trimethylation enforces RNA polymerase II promoter-proximal pausing by blocking hMOF-dependent H4K16 acetylation. Molecular and Cellular Biology. 31: 1594-609. PMID 21321083 DOI: 10.1128/Mcb.00524-10 |
0.759 |
|
2011 |
Thaiparambil JT, Bender L, Ganesh T, Kline E, Patel P, Liu Y, Tighiouart M, Vertino PM, Harvey RD, Garcia A, Marcus A. Abstract 822: Withaferin A inhibits breast cancer invasion and metastasis at subcytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation Cancer Research. 71: 822-822. DOI: 10.1158/1538-7445.Am2011-822 |
0.78 |
|
2010 |
Hashimoto H, Vertino PM, Cheng X. Molecular coupling of DNA methylation and histone methylation. Epigenomics. 2: 657-69. PMID 21339843 DOI: 10.2217/Epi.10.44 |
0.419 |
|
2010 |
Iskow RC, McCabe MT, Mills RE, Torene S, Pittard WS, Neuwald AF, Van Meir EG, Vertino PM, Devine SE. Natural mutagenesis of human genomes by endogenous retrotransposons. Cell. 141: 1253-61. PMID 20603005 DOI: 10.1016/J.Cell.2010.05.020 |
0.312 |
|
2010 |
Kagey JD, Kapoor-Vazirani P, McCabe MT, Powell DR, Vertino PM. Long-term stability of demethylation after transient exposure to 5-aza-2'-deoxycytidine correlates with sustained RNA polymerase II occupancy. Molecular Cancer Research : McR. 8: 1048-59. PMID 20587535 DOI: 10.1158/1541-7786.Mcr-10-0189 |
0.756 |
|
2010 |
Lund MJ, Butler EN, Hair BY, Ward KC, Andrews JH, Oprea-Ilies G, Bayakly AR, O'Regan RM, Vertino PM, Eley JW. Age/race differences in HER2 testing and in incidence rates for breast cancer triple subtypes: a population-based study and first report. Cancer. 116: 2549-59. PMID 20336785 DOI: 10.1002/Cncr.25016 |
0.368 |
|
2010 |
McCabe MT, Powell DR, Zhou W, Vertino PM. Homozygous deletion of the STK11/LKB1 locus and the generation of novel fusion transcripts in cervical cancer cells. Cancer Genetics and Cytogenetics. 197: 130-41. PMID 20193846 DOI: 10.1016/J.Cancergencyto.2009.11.017 |
0.48 |
|
2009 |
McCabe MT, Brandes JC, Vertino PM. Cancer DNA methylation: molecular mechanisms and clinical implications. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 3927-37. PMID 19509173 DOI: 10.1158/1078-0432.Ccr-08-2784 |
0.479 |
|
2009 |
Lucas ME, Crider KS, Powell DR, Kapoor-Vazirani P, Vertino PM. Methylation-sensitive regulation of TMS1/ASC by the Ets factor, GA-binding protein-alpha. The Journal of Biological Chemistry. 284: 14698-709. PMID 19324871 DOI: 10.1074/Jbc.M901104200 |
0.8 |
|
2009 |
Parsons MJ, Patel P, Brat DJ, Colbert L, Vertino PM. Silencing of TMS1/ASC promotes resistance to anoikis in breast epithelial cells. Cancer Research. 69: 1706-11. PMID 19223547 DOI: 10.1158/0008-5472.Can-08-2351 |
0.759 |
|
2009 |
McCabe MT, Lee EK, Vertino PM. A multifactorial signature of DNA sequence and polycomb binding predicts aberrant CpG island methylation. Cancer Research. 69: 282-91. PMID 19118013 DOI: 10.1158/0008-5472.Can-08-3274 |
0.511 |
|
2008 |
Guo L, Zhong D, Lau S, Liu X, Dong XY, Sun X, Yang VW, Vertino PM, Moreno CS, Varma V, Dong JT, Zhou W. Sox7 Is an independent checkpoint for beta-catenin function in prostate and colon epithelial cells. Molecular Cancer Research : McR. 6: 1421-30. PMID 18819930 DOI: 10.1158/1541-7786.Mcr-07-2175 |
0.339 |
|
2008 |
Zhong D, Liu X, Khuri FR, Sun SY, Vertino PM, Zhou W. LKB1 is necessary for Akt-mediated phosphorylation of proapoptotic proteins. Cancer Research. 68: 7270-7. PMID 18794113 DOI: 10.1158/0008-5472.Can-08-1484 |
0.398 |
|
2008 |
Kapoor-Vazirani P, Kagey JD, Powell DR, Vertino PM. Role of hMOF-dependent histone H4 lysine 16 acetylation in the maintenance of TMS1/ASC gene activity. Cancer Research. 68: 6810-21. PMID 18701507 DOI: 10.1158/0008-5472.Can-08-0141 |
0.762 |
|
2008 |
Subramanian K, Jia D, Kapoor-Vazirani P, Powell DR, Collins RE, Sharma D, Peng J, Cheng X, Vertino PM. Regulation of estrogen receptor alpha by the SET7 lysine methyltransferase. Molecular Cell. 30: 336-47. PMID 18471979 DOI: 10.1016/J.Molcel.2008.03.022 |
0.405 |
|
2008 |
Zhang S, Schafer-Hales K, Khuri FR, Zhou W, Vertino PM, Marcus AI. The tumor suppressor LKB1 regulates lung cancer cell polarity by mediating cdc42 recruitment and activity. Cancer Research. 68: 740-8. PMID 18245474 DOI: 10.1158/0008-5472.Can-07-2989 |
0.393 |
|
2008 |
Evans CO, Moreno CS, Zhan X, McCabe MT, Vertino PM, Desiderio DM, Oyesiku NM. Molecular pathogenesis of human prolactinomas identified by gene expression profiling, RT-qPCR, and proteomic analyses. Pituitary. 11: 231-45. PMID 18183490 DOI: 10.1007/S11102-007-0082-2 |
0.323 |
|
2007 |
Saxena NK, Vertino PM, Anania FA, Sharma D. leptin-induced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3. The Journal of Biological Chemistry. 282: 13316-25. PMID 17344214 DOI: 10.1074/Jbc.M609798200 |
0.496 |
|
2007 |
Sun X, Zhou Y, Otto KB, Wang M, Chen C, Zhou W, Subramanian K, Vertino PM, Dong JT. Infrequent mutation of ATBF1 in human breast cancer. Journal of Cancer Research and Clinical Oncology. 133: 103-5. PMID 16932943 DOI: 10.1007/S00432-006-0148-Y |
0.516 |
|
2006 |
Zhong D, Guo L, de Aguirre I, Liu X, Lamb N, Sun SY, Gal AA, Vertino PM, Zhou W. LKB1 mutation in large cell carcinoma of the lung. Lung Cancer (Amsterdam, Netherlands). 53: 285-94. PMID 16822578 DOI: 10.1016/J.Lungcan.2006.05.018 |
0.379 |
|
2006 |
Sharma D, Saxena NK, Davidson NE, Vertino PM. Restoration of tamoxifen sensitivity in estrogen receptor-negative breast cancer cells: tamoxifen-bound reactivated ER recruits distinctive corepressor complexes. Cancer Research. 66: 6370-8. PMID 16778215 DOI: 10.1158/0008-5472.Can-06-0402 |
0.479 |
|
2006 |
Sharma D, Saxena NK, Vertino PM, Anania FA. Leptin promotes the proliferative response and invasiveness in human endometrial cancer cells by activating multiple signal-transduction pathways. Endocrine-Related Cancer. 13: 629-40. PMID 16728588 DOI: 10.1677/Erc.1.01169 |
0.45 |
|
2006 |
Parsons MJ, Vertino PM. Dual role of TMS1/ASC in death receptor signaling. Oncogene. 25: 6948-58. PMID 16715133 DOI: 10.1038/Sj.Onc.1209684 |
0.758 |
|
2006 |
Feltus FA, Lee EK, Costello JF, Plass C, Vertino PM. DNA motifs associated with aberrant CpG island methylation. Genomics. 87: 572-9. PMID 16487676 DOI: 10.1016/J.Ygeno.2005.12.016 |
0.426 |
|
2005 |
De Aguirre I, Zhong D, Zhou W, Rosell R, Vertino P. PD-008 LKB1/AMPK/TSC2 signaling pathway alterations in non-small cell lung cancer Lung Cancer. 49: S69. DOI: 10.1016/S0169-5002(05)80340-X |
0.324 |
|
2004 |
Stone AR, Bobo W, Brat DJ, Devi NS, Van Meir EG, Vertino PM. Aberrant methylation and down-regulation of TMS1/ASC in human glioblastoma. The American Journal of Pathology. 165: 1151-61. PMID 15466382 DOI: 10.1016/S0002-9440(10)63376-7 |
0.463 |
|
2004 |
Sharma D, Vertino PM. Epigenetic regulation of MDR1 gene in breast cancer: CpG methylation status dominates the stable maintenance of a silent gene. Cancer Biology & Therapy. 3: 549-50. PMID 15254426 DOI: 10.4161/Cbt.3.6.1041 |
0.493 |
|
2004 |
McConnell BB, Vertino PM. TMS1/ASC: the cancer connection. Apoptosis : An International Journal On Programmed Cell Death. 9: 5-18. PMID 14739594 DOI: 10.1023/B:Appt.0000012117.32430.0C |
0.442 |
|
2003 |
Feltus FA, Lee EK, Costello JF, Plass C, Vertino PM. Predicting aberrant CpG island methylation Proceedings of the National Academy of Sciences of the United States of America. 100: 12253-12258. PMID 14519846 DOI: 10.1073/Pnas.2037852100 |
0.447 |
|
2003 |
Levine JJ, Stimson-Crider KM, Vertino PM. Effects of methylation on expression of TMS1/ASC in human breast cancer cells. Oncogene. 22: 3475-88. PMID 12776200 DOI: 10.1038/Sj.Onc.1206430 |
0.787 |
|
2002 |
Vertino PM, Sekowski JA, Coll JM, Applegren N, Han S, Hickey RJ, Malkas LH. DNMT1 is a component of a multiprotein DNA replication complex. Cell Cycle (Georgetown, Tex.). 1: 416-23. PMID 12548018 DOI: 10.4161/Cc.1.6.270 |
0.398 |
|
2002 |
Costello JF, Vertino PM. Methylation matters: A new spin on maspin Nature Genetics. 31: 123-124. PMID 12040372 DOI: 10.1038/Ng0602-123 |
0.4 |
|
2002 |
Stimson KM, Vertino PM. Methylation-mediated silencing of TMS1/ASC is accompanied by histone hypoacetylation and CpG island-localized changes in chromatin architecture. The Journal of Biological Chemistry. 277: 4951-8. PMID 11733524 DOI: 10.1074/Jbc.M109809200 |
0.5 |
|
2002 |
Bobo W, Stone A, Brat D, Devi S, Meir E, Vertino P. Methylation of the novel apoptotic gene TMS1/ASC in human glioblastoma multiforme International Journal of Radiation Oncology*Biology*Physics. 54: 175. DOI: 10.1016/S0360-3016(02)03360-6 |
0.393 |
|
2001 |
Marfatia KA, Harreman MT, Fanara P, Vertino PM, Corbett AH. Identification and characterization of the human MOG1 gene. Gene. 266: 45-56. PMID 11290418 DOI: 10.1016/S0378-1119(01)00364-X |
0.319 |
|
1998 |
Mikovits JA, Young HA, Vertino P, Issa JP, Pitha PM, Turcoski-Corrales S, Taub DD, Petrow CL, Baylin SB, Ruscetti FW. Infection with human immunodeficiency virus type 1 upregulates DNA methyltransferase, resulting in de novo methylation of the gamma interferon (IFN-gamma) promoter and subsequent downregulation of IFN-gamma production. Molecular and Cellular Biology. 18: 5166-77. PMID 9710601 DOI: 10.1128/Mcb.18.9.5166 |
0.382 |
|
1998 |
Ferguson AT, Vertino PM, Spitzner JR, Baylin SB, Muller MT, Davidson NE. Role of estrogen receptor gene demethylation and DNA methyltransferase.DNA adduct formation in 5-aza-2'deoxycytidine-induced cytotoxicity in human breast cancer cells. The Journal of Biological Chemistry. 272: 32260-6. PMID 9405430 DOI: 10.1074/Jbc.272.51.32260 |
0.477 |
|
1998 |
Baylin SB, Herman JG, Graff JR, Vertino PM, Issa JP. Alterations In Dna Methylation : A Fundamental Aspect Of Neoplasia Advances in Cancer Research. 72: 141-196. DOI: 10.1016/S0065-230X(08)60702-2 |
0.456 |
|
1997 |
Graff JR, Herman JG, Myöhänen S, Baylin SB, Vertino PM. Mapping patterns of CpG island methylation in normal and neoplastic cells implicates both upstream and downstream regions in de Novo methylation Journal of Biological Chemistry. 272: 22322-22329. PMID 9268383 DOI: 10.1074/Jbc.272.35.22322 |
0.437 |
|
1997 |
Yoder JA, Yen RW, Vertino PM, Bestor TH, Baylin SB. New 5' regions of the murine and human genes for DNA (cytosine-5)-methyltransferase. The Journal of Biological Chemistry. 271: 31092-7. PMID 8940105 DOI: 10.1074/Jbc.271.49.31092 |
0.433 |
|
1996 |
Issa JP, Vertino PM, Boehm CD, Newsham IF, Baylin SB. Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 93: 11757-62. PMID 8876210 DOI: 10.1073/Pnas.93.21.11757 |
0.435 |
|
1996 |
Vertino PM, Yen RW, Gao J, Baylin SB. De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase. Molecular and Cellular Biology. 16: 4555-65. PMID 8754856 DOI: 10.1128/Mcb.16.8.4555 |
0.439 |
|
1993 |
Issa JP, Vertino PM, Wu J, Sazawal S, Celano P, Nelkin BD, Hamilton SR, Baylin SB. Increased cytosine DNA-methyltransferase activity during colon cancer progression. Journal of the National Cancer Institute. 85: 1235-40. PMID 8331684 DOI: 10.1093/Jnci/85.15.1235 |
0.435 |
|
1992 |
Yen RW, Vertino PM, Nelkin BD, Yu JJ, el-Deiry W, Cumaraswamy A, Lennon GG, Trask BJ, Celano P, Baylin SB. Isolation and characterization of the cDNA encoding human DNA methyltransferase. Nucleic Acids Research. 20: 2287-91. PMID 1594447 DOI: 10.1093/Nar/20.9.2287 |
0.363 |
|
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