☰

Erinn B. Rankin, Ph.D. - Publications

Affiliations: 
2007 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Molecular Biology, Cell Biology, Genetics
Tree Info Grants Similar researchers PubMed Report error

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Mehibel M, Xu Y, Li CG, Moon EJ, Thakkar KN, Diep AN, Kim RK, Bloomstein JD, Xiao Y, Bacal J, Saldivar JC, Le QT, Cimprich KA, Rankin EB, Giaccia AJ. Eliminating hypoxic tumor cells improves response to PARP inhibitors in homologous recombination-deficient cancer models. The Journal of Clinical Investigation. 131. PMID 34060485 DOI: 10.1172/JCI146256  0.307
2020 Xiao Y, Thakkar KN, Zhao H, Broughton J, Li Y, Seoane JA, Diep AN, Metzner TJ, von Eyben R, Dill DL, Brooks JD, Curtis C, Leppert JT, Ye J, Peehl DM, ... ... Rankin EB, et al. The mA RNA demethylase FTO is a HIF-independent synthetic lethal partner with the VHL tumor suppressor. Proceedings of the National Academy of Sciences of the United States of America. PMID 32817424 DOI: 10.1073/Pnas.2000516117  0.48
2020 Aguilera TA, Elghonaimy E, Shehade H, Rafat M, Castellini L, Jiang D, Kariolis M, Koong A, Le QT, Ellies LG, Rankin EB, Graves EE, Giaccia AJ. Induced tumor heterogeneity reveals factors informing radiation and immunotherapy combinations. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32098769 DOI: 10.1158/1078-0432.Ccr-19-4220  0.319
2020 Li AM, Ducker GS, Li Y, Seoane JA, Xiao Y, Melemenidis S, Zhou Y, Liu L, Vanharanta S, Graves EE, Rankin EB, Curtis C, Massague J, Rabinowitz JD, Thompson CB, et al. Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism. Molecular Cancer Research : McR. PMID 31941752 DOI: 10.1158/1541-7786.Mcr-19-0606  0.329
2020 Li AM, Ducker GS, Li Y, Seoane JA, Xiao Y, Melemenidis S, Zhou Y, Liu L, Vanharanta S, Graves EE, Rankin EB, Curtis C, Massague J, Rabinowitz JD, Thompson CB, et al. Abstract 5713: Reprogramming of serine metabolism during breast cancer progression Cancer Research. 80: 5713-5713. DOI: 10.1158/1538-7445.Am2020-5713  0.347
2019 Xiao Y, Zhao H, Tian L, Nolley R, Diep AN, Ernst A, Fuh KC, Miao YR, von Eyben R, Leppert JT, Brooks JD, Peehl DM, Giaccia AJ, Rankin EB. S100A10 is a critical mediator of GAS6/AXL-induced angiogenesis in renal cell carcinoma. Cancer Research. PMID 31585940 DOI: 10.1158/0008-5472.Can-19-1366  0.437
2019 Qian J, Rankin EB. Hypoxia-Induced Phenotypes that Mediate Tumor Heterogeneity. Advances in Experimental Medicine and Biology. 1136: 43-55. PMID 31201715 DOI: 10.1007/978-3-030-12734-3_3  0.43
2019 Natarajan S, Foreman KM, Soriano MI, Rossen NS, Shehade H, Fregoso DR, Eggold JT, Krishnan V, Dorigo O, Krieg AJ, Heilshorn SC, Sinha S, Fuh KC, Rankin EB. Collagen remodeling in the hypoxic tumor-mesothelial niche promotes ovarian cancer metastasis. Cancer Research. PMID 30862717 DOI: 10.1158/0008-5472.Can-18-2616  0.404
2019 Levy K, Wang J, Natarajan S, Casey K, Eggold JT, Rafat M, Loo BW, Rankin E. Ultra-rapid total abdominal FLASH irradiation in a preclinical model of ovarian cancer. Journal of Global Oncology. 5: 103-103. DOI: 10.1200/Jgo.2019.5.Suppl.103  0.342
2019 Mehibel M, Xu J, Diep A, Thakkar K, Li CG, Xiao Y, Rankin E, Giaccia A. Modulating the tumor microenvironment to enhance efficacy of PARP inhibitors. Journal of Clinical Oncology. 37: e14715-e14715. DOI: 10.1200/Jco.2019.37.15_Suppl.E14715  0.404
2019 Natarajan S, Foreman K, Soriano M, Shehade H, Fregoso D, Eggold J, Rosen NS, Heilshorn S, Krieg AJ, Krishnan V, Dorigo O, Sinha S, Fuh KC, Rankin EB. Abstract TMIM-081: THE HYPOXIC TUMOR-MESOTHELIAL NICHE PROMOTES OVARIAN CANCER METASTASIS THROUGH COLLAGEN REMODELING Clinical Cancer Research. 25. DOI: 10.1158/1557-3265.Ovcasymp18-Tmim-081  0.427
2019 Levy K, Eggold J, Rafat M, Schuler E, Shehade H, Fregoso D, Vilches-Moure J, Koong A, Maxim P, Loo BW, Rankin E. Abstract AP25: TOTAL ABDOMINAL ULTRA-RAPID FLASH IRRADIATION DEMONSTRATES DECREASED GASTROINTESTINAL TOXICITY COMPARED TO CONVENTIONAL TOTAL ABDOMINAL IRRADIATION IN MICE Clinical Cancer Research. 25. DOI: 10.1158/1557-3265.Ovcasymp18-Ap25  0.318
2018 Eggold JT, Rankin EB. Erythropoiesis, EPO, macrophages, and bone. Bone. PMID 29551752 DOI: 10.1016/J.Bone.2018.03.014  0.309
2017 Wu PH, Onodera Y, Ichikawa Y, Rankin EB, Giaccia AJ, Watanabe Y, Qian W, Hashimoto T, Shirato H, Nam JM. Targeting integrins with RGD-conjugated gold nanoparticles in radiotherapy decreases the invasive activity of breast cancer cells. International Journal of Nanomedicine. 12: 5069-5085. PMID 28860745 DOI: 10.2147/Ijn.S137833  0.31
2016 Rankin EB, Nam JM, Giaccia AJ. Hypoxia: Signaling the Metastatic Cascade. Trends in Cancer. 2: 295-304. PMID 28741527 DOI: 10.1016/J.Trecan.2016.05.006  0.461
2016 Aguilera TA, Rafat M, Castellini L, Shehade H, Kariolis MS, Hui AB, Stehr H, von Eyben R, Jiang D, Ellies LG, Koong AC, Diehn M, Rankin EB, Graves EE, Giaccia AJ. Reprogramming the immunological microenvironment through radiation and targeting Axl. Nature Communications. 7: 13898. PMID 28008921 DOI: 10.1038/Ncomms13898  0.324
2016 Kariolis MS, Miao YR, Diep A, Nash SE, Olcina MM, Jiang D, Jones DS, Kapur S, Mathews II, Koong AC, Rankin EB, Cochran JR, Giaccia AJ. Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies. The Journal of Clinical Investigation. PMID 27893463 DOI: 10.1172/Jci85610  0.334
2016 Rankin EB, Giaccia AJ. The Receptor Tyrosine Kinase AXL in Cancer Progression. Cancers. 8. PMID 27834845 DOI: 10.3390/Cancers8110103  0.373
2016 Divine LM, Nguyen MR, Meller E, Desai RA, Arif B, Rankin EB, Bligard KH, Meyerson C, Hagemann IS, Massad M, Thaker PH, Hagemann AR, McCourt CK, Powell MA, Mutch DG, et al. AXL modulates extracellular matrix protein expression and is essential for invasion and metastasis in endometrial cancer. Oncotarget. PMID 27764792 DOI: 10.18632/Oncotarget.12637  0.324
2016 Zhao H, Nolley R, Chan AM, Rankin EB, Peehl DM. Cabozantinib inhibits tumor growth and metastasis of a patient-derived xenograft model of papillary renal cell carcinoma with MET mutation. Cancer Biology & Therapy. 0. PMID 27715452 DOI: 10.1080/15384047.2016.1219816  0.384
2016 Mirzamohammadi F, Papaioannou G, Inloes JB, Rankin EB, Xie H, Schipani E, Orkin SH, Kobayashi T. Polycomb repressive complex 2 regulates skeletal growth by suppressing Wnt and TGF-β signalling. Nature Communications. 7: 12047. PMID 27329220 DOI: 10.1038/Ncomms12047  0.336
2016 Rankin EB, Giaccia AJ. Hypoxic control of metastasis. Science (New York, N.Y.). 352: 175-80. PMID 27124451 DOI: 10.1126/Science.Aaf4405  0.483
2016 Rankin EB, Nam JM, Giaccia AJ. Hypoxia: Signaling the Metastatic Cascade Trends in Cancer. 2: 295-304. DOI: 10.1016/j.trecan.2016.05.006  0.363
2015 Zhou L, Liu XD, Sun M, Zhang X, German P, Bai S, Ding Z, Tannir N, Wood CG, Matin SF, Karam JA, Tamboli P, Sircar K, Rao P, Rankin EB, et al. Targeting MET and AXL overcomes resistance to sunitinib therapy in renal cell carcinoma. Oncogene. PMID 26364599 DOI: 10.1038/Onc.2015.343  0.401
2015 Wu C, Rankin EB, Castellini L, Fernandez-Alcudia J, LaGory EL, Andersen R, Rhodes SD, Wilson TL, Mohammad KS, Castillo AB, Guise TA, Schipani E, Giaccia AJ. Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin. Genes & Development. 29: 817-31. PMID 25846796 DOI: 10.1101/Gad.255000.114  0.362
2015 Finger EC, Castellini L, Rankin EB, Vilalta M, Krieg AJ, Jiang D, Banh A, Zundel W, Powell MB, Giaccia AJ. Hypoxic induction of AKAP12 variant 2 shifts PKA-mediated protein phosphorylation to enhance migration and metastasis of melanoma cells. Proceedings of the National Academy of Sciences of the United States of America. 112: 4441-6. PMID 25792458 DOI: 10.1073/Pnas.1418164112  0.383
2015 Fuh K, Rankin E, Wu C, Diep A, Giaccia AJ. Abstract AS19: The role of the receptor tyrosine kinase AXL in an immunocompetent mouse model of invasive endometrioid ovarian cancer Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Ovcasymp14-As19  0.301
2014 Rankin EB, Fuh KC, Castellini L, Viswanathan K, Finger EC, Diep AN, LaGory EL, Kariolis MS, Chan A, Lindgren D, Axelson H, Miao YR, Krieg AJ, Giaccia AJ. Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET. Proceedings of the National Academy of Sciences of the United States of America. 111: 13373-8. PMID 25187556 DOI: 10.1073/Pnas.1404848111  0.461
2014 Mangiavini L, Merceron C, Araldi E, Khatri R, Gerard-O'Riley R, Wilson TL, Rankin EB, Giaccia AJ, Schipani E. Loss of VHL in mesenchymal progenitors of the limb bud alters multiple steps of endochondral bone development. Developmental Biology. 393: 124-36. PMID 24972088 DOI: 10.1016/J.Ydbio.2014.06.013  0.384
2014 Taniguchi CM, Miao YR, Diep AN, Wu C, Rankin EB, Atwood TF, Xing L, Giaccia AJ. PHD inhibition mitigates and protects against radiation-induced gastrointestinal toxicity via HIF2. Science Translational Medicine. 6: 236ra64. PMID 24828078 DOI: 10.1126/Scitranslmed.3008523  0.351
2014 Finger EC, Cheng CF, Williams TR, Rankin EB, Bedogni B, Tachiki L, Spong S, Giaccia AJ, Powell MB. CTGF is a therapeutic target for metastatic melanoma. Oncogene. 33: 1093-100. PMID 23435419 DOI: 10.1038/Onc.2013.47  0.4
2013 Schipani E, Wu C, Rankin EB, Giaccia AJ. Regulation of Bone Marrow Angiogenesis by Osteoblasts during Bone Development and Homeostasis. Frontiers in Endocrinology. 4: 85. PMID 23847596 DOI: 10.3389/Fendo.2013.00085  0.332
2012 Wu C, Rankin EB, Giaccia AJ. Blood and bones: osteoblastic HIF signaling regulates erythropoiesis. Cell Cycle (Georgetown, Tex.). 11: 2221-2. PMID 22627672 DOI: 10.4161/Cc.20635  0.306
2012 Rankin EB, Wu C, Khatri R, Wilson TL, Andersen R, Araldi E, Rankin AL, Yuan J, Kuo CJ, Schipani E, Giaccia AJ. The HIF signaling pathway in osteoblasts directly modulates erythropoiesis through the production of EPO. Cell. 149: 63-74. PMID 22464323 DOI: 10.1016/J.Cell.2012.01.051  0.393
2011 Rankin EB, Giaccia AJ, Schipani E. A central role for hypoxic signaling in cartilage, bone, and hematopoiesis. Current Osteoporosis Reports. 9: 46-52. PMID 21360287 DOI: 10.1007/S11914-011-0047-2  0.441
2011 Finger EC, Banh A, Rankin EB, Vilalta M, Krieg AJ, Broome-Powell M, Giaccia AJ. Abstract 1460: AKAP12 regulates melanoma tumor growth and metastasis Cancer Research. 71: 1460-1460. DOI: 10.1158/1538-7445.Am2011-1460  0.397
2010 Rankin EB, Fuh KC, Taylor TE, Krieg AJ, Musser M, Yuan J, Wei K, Kuo CJ, Longacre TA, Giaccia AJ. AXL is an essential factor and therapeutic target for metastatic ovarian cancer. Cancer Research. 70: 7570-9. PMID 20858715 DOI: 10.1158/0008-5472.Can-10-1267  0.382
2010 Krieg AJ, Rankin EB, Chan D, Razorenova O, Fernandez S, Giaccia AJ. Regulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1 alpha enhances hypoxic gene expression and tumor growth. Molecular and Cellular Biology. 30: 344-53. PMID 19858293 DOI: 10.1128/Mcb.00444-09  0.485
2009 Rankin EB, Rha J, Selak MA, Unger TL, Keith B, Liu Q, Haase VH. Hypoxia-inducible factor 2 regulates hepatic lipid metabolism. Molecular and Cellular Biology. 29: 4527-38. PMID 19528226 DOI: 10.1128/Mcb.00200-09  0.701
2009 Rankin EB, Giaccia AJ, Hammond EM. Bringing H2AX into the angiogenesis family. Cancer Cell. 15: 459-61. PMID 19477424 DOI: 10.1016/J.Ccr.2009.05.004  0.316
2008 Kimura K, Iwano M, Higgins DF, Yamaguchi Y, Nakatani K, Harada K, Kubo A, Akai Y, Rankin EB, Neilson EG, Haase VH, Saito Y. Stable expression of HIF-1alpha in tubular epithelial cells promotes interstitial fibrosis. American Journal of Physiology. Renal Physiology. 295: F1023-9. PMID 18667485 DOI: 10.1152/Ajprenal.90209.2008  0.717
2008 Rankin EB, Rha J, Unger TL, Wu CH, Shutt HP, Johnson RS, Simon MC, Keith B, Haase VH. Hypoxia-inducible factor-2 regulates vascular tumorigenesis in mice. Oncogene. 27: 5354-8. PMID 18490920 DOI: 10.1038/Onc.2008.160  0.737
2008 Rankin EB, Giaccia AJ. The role of hypoxia-inducible factors in tumorigenesis. Cell Death and Differentiation. 15: 678-85. PMID 18259193 DOI: 10.1038/Cdd.2008.21  0.508
2007 Peyssonnaux C, Zinkernagel AS, Schuepbach RA, Rankin E, Vaulont S, Haase VH, Nizet V, Johnson RS. Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs). The Journal of Clinical Investigation. 117: 1926-32. PMID 17557118 DOI: 10.1172/Jci31370  0.675
2007 Rankin EB, Biju MP, Liu Q, Unger TL, Rha J, Johnson RS, Simon MC, Keith B, Haase VH. Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo. The Journal of Clinical Investigation. 117: 1068-77. PMID 17404621 DOI: 10.1172/Jci30117  0.725
2006 Rankin EB, Tomaszewski JE, Haase VH. Renal cyst development in mice with conditional inactivation of the von Hippel-Lindau tumor suppressor. Cancer Research. 66: 2576-83. PMID 16510575 DOI: 10.1158/0008-5472.Can-05-3241  0.696
2005 Rankin EB, Higgins DF, Walisser JA, Johnson RS, Bradfield CA, Haase VH. Inactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice. Molecular and Cellular Biology. 25: 3163-72. PMID 15798202 DOI: 10.1128/Mcb.25.8.3163-3172.2005  0.737
2004 Rankin EB, Xu W, Silberg DG, Suh E. Putative intestine-specific enhancers located in 5′ sequence of the CDX1 gene regulate CDX1 expression in the intestine American Journal of Physiology - Gastrointestinal and Liver Physiology. 286. PMID 14715525 DOI: 10.1152/Ajpgi.00326.2003  0.339
2003 Rankin EB, Song F, Suh E. CDXI is inactivated by methylation and histone deacetylation in colon cancer Gastroenterology. 124: A283. DOI: 10.1016/S0016-5085(03)81418-X  0.357
2002 Suh ER, Ha CS, Rankin EB, Toyota M, Traber PG. DNA methylation down-regulates CDX1 gene expression in colorectal cancer cell lines. The Journal of Biological Chemistry. 277: 35795-800. PMID 12124393 DOI: 10.1074/Jbc.M205567200  0.355
Show low-probability matches.